The document discusses risk factors for alcoholism and drug addiction in the U.S., noting that about 28% of adults drink at risky levels while a significant percentage of youth engage in substance use. Key risk factors include age, gender, family history, race, and psychiatric disorders, with early use often leading to higher addiction rates. Substance abuse affects various demographic groups differently, with increasing rates among women and the elderly, and particular vulnerabilities observed in those with a history of abuse and behavioral disorders.