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Chapter 15
Expectorants and
Antitussive Agents
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 2
Expectorants and
Antitussive Agents
 Drugs that aid in the expectoration
(removal) of mucus
 Reduce the viscosity of secretions
 Stimulate the flow of respiratory
secretions
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 3
Secretions
 By loosening and thinning sputum and
bronchial secretions, the tendency to
cough is indirectly diminished.
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 4
Cough Relief
 Relief of nonproductive coughs:
 Pertussis
 Common cold
 Bronchitis
 Laryngitis
 Sinusitis
 Influenza
 Pharyngitis
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 5
Expectorants: Side Effects
 Common side effects
 Guaifenesin
 Nausea, vomiting
 Gastric irritation
 Terpin hydrate
 Gastric upset (elixir has high alcohol content)
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 6
Expectorants: Nursing
Implications
 Use with caution.
 Elderly
 Encourage client to drink fluids.
 Monitor for therapeutic effects.
 Report a fever lasting longer than a
week.
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 7
Antitussives
 Drugs used to control coughing
 Opioids and nonopioids
 Narcotics
 Used for nonproductive coughs
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 8
Opioid Antitussives
 Suppress the cough reflex by direct
action on the cough center in the medulla
 Example: codeine + guiafenesin =
Robitussin AC
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 9
Non-narcotic Antitussives
 Dextromethorphan
 Suppresses the cough reflex by direct action
on the cough center in the medulla; a
chemical derivative of the opiate narcotics
 Result: diminished cough
 Produces no respiratory depression,
analgesia, or dependence
 Example: Robitussin-DM
(continues)
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 10
Non-narcotic Antitussives
 Benzonatate
 A derivative of procaine (local anesthetic
action); impairs the sensation of the stretch
receptors in the respiratory tract
 Example
 Tessalon
(continued)
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 11
Antitussive Agents: Side Effects
 Benzonatate
 Dizziness, headache, sedation
 Dextromethorphan
 Dizziness, drowsiness, nausea
 Opioids
 Sedation, nausea, vomiting,
lightheadedness, constipation
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 12
Antitussive Agents: Nursing
Interventions
 Perform respiratory assessment.
 Instruct clients to:
 Avoid driving or operating heavy
equipment
 Not drink liquids for 30 to 35 minutes
after taking a cough syrup or using a
cough lozenge
Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.
15 - 13
Antitussive Agents: Client
Teaching
 Report any of the following symptoms to
the health care professional:
 Cough that lasts more than 2 weeks
 A persistent headache
 Fever
 Rash

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Antitussive s and Expectorants.ppt

  • 2. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 2 Expectorants and Antitussive Agents  Drugs that aid in the expectoration (removal) of mucus  Reduce the viscosity of secretions  Stimulate the flow of respiratory secretions
  • 3. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 3 Secretions  By loosening and thinning sputum and bronchial secretions, the tendency to cough is indirectly diminished.
  • 4. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 4 Cough Relief  Relief of nonproductive coughs:  Pertussis  Common cold  Bronchitis  Laryngitis  Sinusitis  Influenza  Pharyngitis
  • 5. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 5 Expectorants: Side Effects  Common side effects  Guaifenesin  Nausea, vomiting  Gastric irritation  Terpin hydrate  Gastric upset (elixir has high alcohol content)
  • 6. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 6 Expectorants: Nursing Implications  Use with caution.  Elderly  Encourage client to drink fluids.  Monitor for therapeutic effects.  Report a fever lasting longer than a week.
  • 7. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 7 Antitussives  Drugs used to control coughing  Opioids and nonopioids  Narcotics  Used for nonproductive coughs
  • 8. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 8 Opioid Antitussives  Suppress the cough reflex by direct action on the cough center in the medulla  Example: codeine + guiafenesin = Robitussin AC
  • 9. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 9 Non-narcotic Antitussives  Dextromethorphan  Suppresses the cough reflex by direct action on the cough center in the medulla; a chemical derivative of the opiate narcotics  Result: diminished cough  Produces no respiratory depression, analgesia, or dependence  Example: Robitussin-DM (continues)
  • 10. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 10 Non-narcotic Antitussives  Benzonatate  A derivative of procaine (local anesthetic action); impairs the sensation of the stretch receptors in the respiratory tract  Example  Tessalon (continued)
  • 11. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 11 Antitussive Agents: Side Effects  Benzonatate  Dizziness, headache, sedation  Dextromethorphan  Dizziness, drowsiness, nausea  Opioids  Sedation, nausea, vomiting, lightheadedness, constipation
  • 12. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 12 Antitussive Agents: Nursing Interventions  Perform respiratory assessment.  Instruct clients to:  Avoid driving or operating heavy equipment  Not drink liquids for 30 to 35 minutes after taking a cough syrup or using a cough lozenge
  • 13. Copyright 2007 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. 15 - 13 Antitussive Agents: Client Teaching  Report any of the following symptoms to the health care professional:  Cough that lasts more than 2 weeks  A persistent headache  Fever  Rash