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Expectorants and
Antitussive Agents
Drugs that aid in the expectoration
(removal) of mucus
Reduce the viscosity of secretions
Stimulate the flow of respiratory
secretions
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Secretions
By loosening and thinning sputum and
bronchial secretions, the tendency to
cough is indirectly diminished.
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Cough Relief
Relief of nonproductive coughs:
Pertussis
Common cold
Bronchitis
Laryngitis
Sinusitis
Influenza
Pharyngitis
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Expectorants: Side Effects
Common side effects
Guaifenesin
Nausea, vomiting
Gastric irritation
Terpin hydrate
Gastric upset (elixir has high alcohol content)
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Expectorants: Nursing
Implications
Use with caution.
Elderly
Encourage client to drink fluids.
Monitor for therapeutic effects.
Report a fever lasting longer than a
week.
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Antitussives
Drugs used to control coughing
Opioids and nonopioids
Narcotics
Used for nonproductive coughs
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Opioid Antitussives
Suppress the cough reflex by direct
action on the cough center in the medulla
Example: codeine + guiafenesin =
Robitussin AC
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Non-narcotic Antitussives
Dextromethorphan
Suppresses the cough reflex by direct action
on the cough center in the medulla; a
chemical derivative of the opiate narcotics
Result: diminished cough
Produces no respiratory depression,
analgesia, or dependence
Example: Robitussin-DM
(continues)
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Non-narcotic Antitussives
Benzonatate
A derivative of procaine (local anesthetic
action); impairs the sensation of the stretch
receptors in the respiratory tract
Example
Tessalon
(continued)
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Antitussive Agents: Side Effects
Benzonatate
Dizziness, headache, sedation
Dextromethorphan
Dizziness, drowsiness, nausea
Opioids
Sedation, nausea, vomiting,
lightheadedness, constipation
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Antitussive Agents: Nursing
Interventions
Perform respiratory assessment.
Instruct clients to:
Avoid driving or operating heavy
equipment
Not drink liquids for 30 to 35 minutes
after taking a cough syrup or using a
cough lozenge
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Antitussive Agents: Client
Teaching
Report any of the following symptoms to
the health care professional:
Cough that lasts more than 2 weeks
A persistent headache
Fever
Rash