8. I-Infectious diarrhea Calf Ages
A-Bacterial Causes:
E. coli <5 da
C. perfringens B, C 5-30 da
Salmonella >15 da
1-Infectious calf diarrhea
المعدى االسهال
11. السالمونيال مرض اسباب
• Salmonella is a genus of gram-negative, facultative
anaerobic bacteria that belong to the family of
Enterobacteriaceae.
• There are 2 recognized species within the genus:
• S .Dublin
• S .Enterica
•
16. بالسالمونيال االصابة ووقت االنتقال طرق
• Salmonella Dublin infection is increasingly common
during the late nursing and postweaning period.
• Salmonella infection is most commonly transmitted
by fecal–oral contamination
• from other livestock,
• Rodents
• birds.
17. Pathogenesis
المرض سير خط
• Salmonella invade the intestinal mucosa, multiply within
the lymphoid tissues, and to evade host defense
mechanisms. الليمفاوية االنسجة فى ويتضاعف االمعاء جدار يخترق الميكروب
• Enterocolitis is due to inflammation with subsequent
maldigestion and malabsorption, and to a lesser extent
from secretory mechanisms.
• Inflammation in the colon leads to the commonly observed
fresh blood in the feces of both adults and calves.
19. اآلتية العوامل على االعراض شدة يتوقف
• The strain of bacteria. العترة نوع
• The immune resistance of the animal infected.
• الحالة
المناعية
للحيوان
• The amount of bacteria taken in.
• كمية
البكتريا
التى
اصيب
بها
الحيوان
•
20. االعراض
1-Septicemic Form:
• This is the characteristic form of the disease in newborn
calves, up to 4 months old.
• Profound depression.
• Dullness.
• prostration.
• high fever (40.5-42°C).
• Death within 24-48 hours.
Septicemia, or sepsis
• is the clinical name for blood
poisoning by bacteria.
• It is the body's most extreme
response to an infection.
• Sepsis that progresses to
septic shock has a death rate
as high as 50%, depending on
the type of organism involved.
21. االعراض
2- Acute entritis.
• Animals look ‘tucked up’ and miserable, may kick at the
belly, and grind their teeth. الحيوانات تبدو
"
مطوية
"
ترفس وقد ، وبائسة
•
أسنانها وتطحن بطنها
.
• fever
• marked dehydration
• Pneumonia
• Respiratory distress (e.g., elevated respiratory rate,
coughing, etc.)
• Arthritis and foci of osteomyelitis
22. االسهال طبيعة
• The diarrhea is watery and may contain blood or mucus.
The diarrhea has a putrid smell that may be suggestive of
salmonellosis.
• Death can occur within a few hours in per acute cases,
and these animals may die before developing diarrhea or
other severe clinical signs.
•
االسهال
مائى
مدمم
او
يحتوى
على
مخاط
•
االسهال
له
رائحة
كريهه
•
يحدث
نفوق
للعجل
بعد
ساعات
قليلة
فى
الحاالت
الحادة
•
23. العشار االبقار فى االجهاض
• 2) Salmonella induced abortion :
• Salmonella dublin infection. دبلن سالمونيال الميكروب
• Abortion usually occurs in the last third of pregnancy.
• االجهاض
يكون
غالبا
فى
الثلث
األخير
الحمل من
• Abortion is often associated with retention of the foetal
membranes. االجهاض بعد للمشيمة احتباس يحدث دائما
30. التشخيص طرق تابع
3-Antibody testing :
Serologic tests to identify specific antibodies in serum or
milk .
4-Isolation of the organism from:
diarrhea, aborted foetus - uterine discharge- organs after
PM
5- (PCR) techniques
6-PM
31. الحادة الحاالت فى التشريحية الصفة
1-Mucoenteritis to diffuse haemorrhagic enteritis
2-Severe necrotic enteritis of ileum and large intestine
caused by S. typhimurium
3-Abomasitis in S. dublin infection
4-Enlarged, edematous and haemorrhagic lymph nodes
5-Thickened inflamed gall bladder wall
6-Fatty change of the enlarged liver
7-Subserous and epicardial haemorrhage
32.
33. الحاالت فى التشريحية الصفة
المزمنة
1-Areas of necrosis in the wall of caecum and colon
2-Swollen mesenteric lymph nodes and spleen
3-Chronic pneumonia
35. أعراض بدون النفوق حالة فى
• Salmonella should be included in the list
of differential diagnoses.
• Thus requiring samples of liver, spleen,
lung, and intestine for complementary
laboratory diagnostic tests.
40. Main Line of Treatment
للعالج العامة الخطوط
Fluid therapy( oral& systemic)
Antiacid.
Antibiotic drugs.
Non steroidal anti-inflammatory
41. 1-Fluid therapy
Administering an oral electrolyte solution between
milk feedings will assist with the management of
dehydration and acidosis.
More severely affected calves would require
intravenous fluid therapy with alkalinizing agents
(e.g., bicarbonate) and energy sources like
dextrose.
45. السالمونيال لعالج الحيوية المضادات افضل
• R/Third-generation cephalosporins:
• Ceftiofur
• R/(2.2 mg/kg given intramuscularly [IM]
• Every 12 h for at least 3 days.
49. الوقاية طرق
The treatment response to all Salmonella
infections is generally poor and
prevention is much better than treatment.
50. األلبان مزارع فى االسهال من الوقاية أساسيات
• The 3 main principles of diarrhea prevention in both beef
and dairy cattle include:
• (1) Vaccine in late gestation cattle ( Escherichia coli,
rotavirus, and coronavirus;).
• (2) A good colostrum program is in place ensuring
adequate intake of immunoglobulins by the calf;
• (3) Sanitation, hygiene, housing, and pasture management.
51. In an outbreak of salmonellosis
مزرعة فى وباء حدوث حالة فى
• Infected animals should be identified and either culled or
isolated. عزل
الحاالت
المصابة
او
التخلص
منها
• Vigorous treatment is required in animals showing signs of
systemic disease. عالج
الحاالت
المريضة
• Treated animals must be rechecked several times to
confirm they are not carriers.
• التأكد
من
الحاالت
التى
تم
عالجها
انها
غير
حاملة
للميكروب
52. الوقاية طرق
The control measures for salmonellosis are based on
sanitation and management.
Individual calf hutches or pens provide adequate
isolation if sufficient spacing and good sanitation are
maintained.
55. Vacination
The Salmonella vaccines presently available provide
limited protection; however, live vaccines made from
auxotrophic strains of Salmonella appear to be more
efficacious.
عمل
لقاحات
من
العترات
المعزولة
محليا
فى
االماكن
المصابة
يعطى
نتائج
أفضل
فى
الوقاية
.