1. How does CRISPR-Cas9 gene silencing differ from siRNA? Specifically, what does each one target for down regulation and how does this contribute to analyzing the function of a gene? (5 points) 2. If you were studying the localization of a gene product in cells, which technology (siRNA or CRISPR) could you use to tag your protein of interest with GFP and why? (3 points).