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1. How does CRISPR-Cas9 gene silencing differ from siRNA? Specifically, what does each one
target for down regulation and how does this contribute to analyzing the function of a gene? (5
points) 2. If you were studying the localization of a gene product in cells, which technology
(siRNA or CRISPR) could you use to tag your protein of interest with GFP and why? (3 points)

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