Boothby an introduction to differentiable manifolds and riemannian geometry

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Riemannian Geometry

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ERTHROPOIESIS: Dr. E. Muralinath & R. Gnana Lahari

muralinath2

Cell Immobilization Methods and Applications.pptx

Cherry

There are two types of lymphocytes namely B-cells and T-cells, which are critical for the immune system. In addition, several accessory cells and effector cells also participate. The site of development and maturation of B-cells occurs in bursa fabricius in birds, and bone marrow in mammals. During the course of immune response. B-cells mature into plasma cells and secrete antibodies (immunoglobulins). The B-cells possess the capability to specifically recognize each antigen and produce antibodies (i.e. immunoglobulins) against it.

B lymphocytes, Receptors, Maturation and Activation

Bhanu Krishan

The highest priority recommendation of the Astro2020 Decadal Survey for space-based astronomy was the construction of an observatory capable of characterizing habitable worlds. In this paper series we explore the detectability of and interference from exomoons and exorings serendipitously observed with the proposed Habitable Worlds Observatory (HWO) as it seeks to characterize exoplanets, starting in this manuscript with Earth-Moon analog mutual events. Unlike transits, which only occur in systems viewed near edge-on, shadow (i.e., solar eclipse) and lunar eclipse mutual events occur in almost every star-planet-moon system. The cadence of these events can vary widely from ∼yearly to multiple events per day, as was the case in our younger Earth-Moon system. Leveraging previous space-based (EPOXI) lightcurves of a Moon transit and performance predictions from the LUVOIR-B concept, we derive the detectability of Moon analogs with HWO. We determine that Earth-Moon analogs are detectable with observation of ∼2-20 mutual events for systems within 10 pc, and larger moons should remain detectable out to 20 pc. We explore the extent to which exomoon mutual events can mimic planet features and weather. We find that HWO wavelength coverage in the near-IR, specifically in the 1.4 µm water band where large moons can outshine their host planet, will aid in differentiating exomoon signals from exoplanet variability. Finally, we predict that exomoons formed through collision processes akin to our Moon are more likely to be detected in younger systems, where shorter orbital periods and favorable geometry enhance the probability and frequency of mutual events.

Exomoons & Exorings with the Habitable Worlds Observatory I: On the Detection...

Sérgio Sacani

Mitosis...............................pptx

Cherry

Hadean zircons provide a potential record of Earth's earliest subduction 4.3 billion years ago. Itremains enigmatic how subduction could be initiated so soon after the presumably Moon‐forming giant impact(MGI). Earlier studies found an increase in Earth's core‐mantle boundary (CMB) temperature due to theaccumulation of the impactor's core, and our recent work shows Earth's lower mantle remains largely solid, withsome of the impactor's mantle potentially surviving as the large low‐shear velocity provinces (LLSVPs). Here,we show that a hot post‐impact CMB drives the initiation of strong mantle plumes that can induce subductioninitiation ∼200 Myr after the MGI. 2D and 3D thermomechanical computations show that a high CMBtemperature is the primary factor triggering early subduction, with enrichment of heat‐producing elements inLLSVPs as another potential factor. The models link the earliest subduction to the MGI with implications forunderstanding the diverse tectonic regimes of rocky planets.

A Giant Impact Origin for the First Subduction on Earth

Sérgio Sacani

Triploidy ...............................pptx

Cherry

The concepts of plant disease management are primarily centered on identifying the disease and reducing damage or loss below the threshold of economic detriment. Whetzel (1919) was the first to define disease control approaches as Exclusion, Eradication, Protection, and Resistance, with two more methods added later: Avoidance and Therapy (National Science Academy, 1968). Thus, management methods refer to steps done to lower the incidence and intensity of the illness, limit the number of inoculums that originate and propagate the disease, and, eventually, minimize the disease's losses.

PLANT DISEASE MANAGEMENT PRINCIPLES AND ITS IMPORTANCE

TALAPATI ARUNA CHENNA VYDYANAD

Below are the important points I note from the 2020 paper by Martin Grohe: - 1-WL distinguishes almost all graphs, in a probabilistic sense - Classical WL is two dimensional Weisfeiler-Leman - DeepWL is an unlimited version of WL graph that runs in polynomial time. - Knowledge graphs are essentially graphs with vertex/edge attributes ABSTRACT: Vector representations of graphs and relational structures, whether handcrafted feature vectors or learned representations, enable us to apply standard data analysis and machine learning techniques to the structures. A wide range of methods for generating such embeddings have been studied in the machine learning and knowledge representation literature. However, vector embeddings have received relatively little attention from a theoretical point of view. Starting with a survey of embedding techniques that have been used in practice, in this paper we propose two theoretical approaches that we see as central for understanding the foundations of vector embeddings. We draw connections between the various approaches and suggest directions for future research.

word2vec, node2vec, graph2vec, X2vec: Towards a Theory of Vector Embeddings o...

Subhajit Sahu

GBSN - Microbiology (Unit 6) Human and Microbial interaction

Areesha Ahmad

The recently reported observation of VFTS 243 is the first example of a massive black-hole binary system with negligible binary interaction following black-hole formation. The black-hole mass (≈10M⊙) and near-circular orbit (e ≈ 0.02) of VFTS 243 suggest that the progenitor star experienced complete collapse, with energy-momentum being lost predominantly through neutrinos. VFTS 243 enables us to constrain the natal kick and neutrino-emission asymmetry during black-hole formation. At 68% confidence level, the natal kick velocity (mass decrement) is ≲10 km=s (≲1.0M⊙), with a full probability distribution that peaks when ≈0.3M⊙ were ejected, presumably in neutrinos, and the black hole experienced a natal kick of 4 km=s. The neutrino-emission asymmetry is ≲4%, with best fit values of ∼0–0.2%. Such a small neutrino natal kick accompanying black-hole formation is in agreement with theoretical predictions.

Constraints on Neutrino Natal Kicks from Black-Hole Binary VFTS 243

Sérgio Sacani

Within the uncertainties of involved astronomical and biological parameters, the Drake Equation typically predicts that there should be many exoplanets in our galaxy hosting active, communicative civilizations (ACCs). These optimistic calculations are however not supported by evidence, which is often referred to as the Fermi Paradox. Here, we elaborate on this long-standing enigma by showing the importance of planetary tectonic style for biological evolution. We summarize growing evidence that a prolonged transition from Mesoproterozoic active single lid tectonics (1.6 to 1.0 Ga) to modern plate tectonics occurred in the Neoproterozoic Era (1.0 to 0.541 Ga), which dramatically accelerated emergence and evolution of complex species. We further suggest that both continents and oceans are required for ACCs because early evolution of simple life must happen in water but late evolution of advanced life capable of creating technology must happen on land. We resolve the Fermi Paradox (1) by adding two additional terms to the Drake Equation: foc (the fraction of habitable exoplanets with significant continents and oceans) and fpt (the fraction of habitable exoplanets with significant continents and oceans that have had plate tectonics operating for at least 0.5 Ga); and (2) by demonstrating that the product of foc and fpt is very small (< 0.00003–0.002). We propose that the lack of evidence for ACCs reflects the scarcity of long-lived plate tectonics and/or continents and oceans on exoplanets with primitive life.

The importance of continents, oceans and plate tectonics for the evolution of...

Sérgio Sacani

We report on the discovery of Gliese 12 b, the nearest transiting temperate, Earth-sized planet found to date. Gliese 12 is a bright (V = 12.6 mag, K = 7.8 mag) metal-poor M4V star only 12.162 ± 0.005 pc away from the Solar system with one of the lowest stellar activity levels known for M-dwarfs. A planet candidate was detected by TESS based on only 3 transits in sectors 42, 43, and 57, with an ambiguity in the orbital period due to observational gaps. We performed follow-up transit observations with CHEOPS and ground-based photometry with MINERVA-Australis, SPECULOOS, and Purple Mountain Observatory, as well as further TESS observations in sector 70. We statistically validate Gliese 12 b as a planet with an orbital period of 12.76144 ± 0.00006 d and a radius of 1.0 ± 0.1 R⊕, resulting in an equilibrium temperature of ∼315 K. Gliese 12 b has excellent future prospects for precise mass measurement, which may inform how planetary internal structure is affected by the stellar compositional environment. Gliese 12 b also represents one of the best targets to study whether Earth-like planets orbiting cool stars can retain their atmospheres, a crucial step to advance our understanding of habitability on Earth and across the galaxy.

Gliese 12 b, a temperate Earth-sized planet at 12 parsecs discovered with TES...

Sérgio Sacani

SCHISTOSOMA HEAMATOBIUM life cycle .pdf

DebdattaGhosh6

Recent observations of galaxy clusters and groups with misalignments between their central AGN jets and X-ray cavities, or with multiple misaligned cavities, have raised concerns about the jet – bubble connection in cooling cores, and the processes responsible for jet realignment. To investigate the frequency and causes of such misalignments, we construct a sample of 16 cool core galaxy clusters and groups. Using VLBA radio data we measure the parsec-scale position angle of the jets, and compare it with the position angle of the X-ray cavities detected in Chandra data. Using the overall sample and selected subsets, we consistently find that there is a 30% – 38% chance to find a misalignment larger than ∆Ψ = 45◦ when observing a cluster/group with a detected jet and at least one cavity. We determine that projection may account for an apparently large ∆Ψ only in a fraction of objects (∼35%), and given that gas dynamical disturbances (as sloshing) are found in both aligned and misaligned systems, we exclude environmental perturbation as the main driver of cavity – jet misalignment. Moreover, we find that large misalignments (up to ∼ 90◦ ) are favored over smaller ones (45◦ ≤ ∆Ψ ≤ 70◦ ), and that the change in jet direction can occur on timescales between one and a few tens of Myr. We conclude that misalignments are more likely related to actual reorientation of the jet axis, and we discuss several engine-based mechanisms that may cause these dramatic changes.

Jet reorientation in central galaxies of clusters and groups: insights from V...

Sérgio Sacani

The thermal continuum emission observed from accreting black holes across X-ray bands has the potential to be leveraged as a powerful probe of the mass and spin of the central black hole. The vast majority of existing ‘continuum fitting’ models neglect emission sourced at and within the innermost stable circular orbit (ISCO) of the black hole. Numerical simulations, however, find non-zero emission sourced from these regions. In this work, we extend existing techniques by including the emission sourced from within the plunging region, utilizing new analytical models that reproduce the properties of numerical accretion simulations. We show that in general the neglected intra-ISCO emission produces a hot-and-small quasi-blackbody component, but can also produce a weak power-law tail for more extreme parameter regions. A similar hot-and-small blackbody component has been added in by hand in an ad hoc manner to previous analyses of X-ray binary spectra. We show that the X-ray spectrum of MAXI J1820+070 in a soft-state outburst is extremely well described by a full Kerr black hole disc, while conventional models that neglect intra-ISCO emission are unable to reproduce the data. We believe this represents the first robust detection of intra-ISCO emission in the literature, and allows additional constraints to be placed on the MAXI J1820 + 070 black hole spin which must be low a• < 0.5 to allow a detectable intra-ISCO region. Emission from within the ISCO is the dominant emission component in the MAXI J1820 + 070 spectrum between 6 and 10 keV, highlighting the necessity of including this region. Our continuum fitting model is made publicly available.

Continuum emission from within the plunging region of black hole discs

Sérgio Sacani

The Scientific names of some important families of Industrial plants .pdf

Mohamed Said

Cyanobacteria (also known as blue-green algae) are ubiquitous photosynthetic microorganisms found in diverse habitats such as fresh water, marine water, moist rocks, etc. The photosynthetic mode of nutrition makes them significant global oxygen producers along with nitrogen-fixing ability of heterocyst and carbon sequestration. Some cyanobacterial species have the ability to perform a dual mode of nutritional procurement. This unique capability of cyanobacteria to utilize both organic (heterotrophic) and inorganic (autotrophic) carbon sources for energy production and growth is termed as mixotrophy which impart nutritional flexibility and competitive ability to them. Cyanobacterial mixotrophy provides the promising avenues in biotechnological applications such as wastewater treatment, bioremediation, pharmaceuticals, food supplements, biofertilizer, coloring agents, synthesis of bioactive compounds and as an agent for eco-friendly bio-fuels generation, etc Mixotrophically grown cyanobacteria, demonstrate significant potential for efficient and economical applications beyond their conventional agricultural application, thereby offering a versatile and impactful resource for future technological and environmental challenges.

mixotrophy in cyanobacteria: a dual nutritional strategy

MansiBishnoi1

In this work, we assess the potential detectability of solar panels made of silicon on an Earth-like exoplanet as a potential technosignature. Silicon-based photovoltaic cells have high reflectance in the UV-VIS and in the near-IR, within the wavelength range of a space-based flagship mission concept like the Habitable Worlds Observatory (HWO). Assuming that only solar energy is used to provide the 2022 human energy needs with a land cover of ∼ 2.4%, and projecting the future energy demand assuming various growth-rate scenarios, we assess the detectability with an 8 m HWO-like telescope. Assuming the most favorable viewing orientation, and focusing on the strong absorption edge in the ultraviolet-to-visible (0.34 − 0.52 µm), we find that several 100s of hours of observation time is needed to reach a SNR of 5 for an Earth-like planet around a Sun-like star at 10pc, even with a solar panel coverage of ∼ 23% land coverage of a future Earth. We discuss the necessity of concepts like Kardeshev Type I/II civilizations and Dyson spheres, which would aim to harness vast amounts of energy. Even with much larger populations than today, the total energy use of human civilization would be orders of magnitude below the threshold for causing direct thermal heating or reaching the scale of a Kardashev Type I civilization. Any extraterrrestrial civilization that likewise achieves sustainable population levels may also find a limit on its need to expand, which suggests that a galaxy-spanning civilization as imagined in the Fermi paradox may not exist.

Detectability of Solar Panels as a Technosignature

Sérgio Sacani

Mammals have dominated Earth for approximately 55 Myr thanks to their adaptations and resilience to warming and cooling during the Cenozoic. All life will eventually perish in a runaway greenhouse once absorbed solar radiation exceeds the emission of thermal radiation in several billions of years. However, conditions rendering the Earth naturally inhospitable to mammals may develop sooner because of long-term processes linked to plate tectonics (short-term perturbations are not considered here). In ~250 Myr, all continents will converge to form Earth’s next supercontinent, Pangea Ultima. A natural consequence of the creation and decay of Pangea Ultima will be extremes in pCO2 due to changes in volcanic rifting and outgassing. Here we show that increased pCO2, solar energy (F⨀; approximately +2.5% W m−2 greater than today) and continentality (larger range in temperatures away from the ocean) lead to increasing warming hostile to mammalian life. We assess their impact on mammalian physiological limits (dry bulb, wet bulb and Humidex heat stress indicators) as well as a planetary habitability index. Given mammals’ continued survival, predicted background pCO2 levels of 410–816 ppm combined with increased F⨀ will probably lead to a climate tipping point and their mass extinction. The results also highlight how global landmass configuration, pCO2 and F⨀ play a critical role in planetary habitability.

Climate extremes likely to drive land mammal extinction during next supercont...

Sérgio Sacani

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ERTHROPOIESIS: Dr. E. Muralinath & R. Gnana Lahari

Cell Immobilization Methods and Applications.pptx

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Mitosis...............................pptx

A Giant Impact Origin for the First Subduction on Earth

Triploidy ...............................pptx

PLANT DISEASE MANAGEMENT PRINCIPLES AND ITS IMPORTANCE

word2vec, node2vec, graph2vec, X2vec: Towards a Theory of Vector Embeddings o...

GBSN - Microbiology (Unit 6) Human and Microbial interaction

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Jet reorientation in central galaxies of clusters and groups: insights from V...

Continuum emission from within the plunging region of black hole discs

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mixotrophy in cyanobacteria: a dual nutritional strategy

Detectability of Solar Panels as a Technosignature

Climate extremes likely to drive land mammal extinction during next supercont...

Featured

ChatGPT is a revolutionary addition to the world since its introduction in 2022. A big shift in the sector of information gathering and processing happened because of this chatbot. What is the story of ChatGPT? How is the bot responding to prompts and generating contents? Swipe through these slides prepared by Expeed Software, a web development company regarding the development and technical intricacies of ChatGPT!

Everything You Need To Know About ChatGPT

Expeed Software

Product Design Trends in 2024 | Teenage Engineerings

Pixeldarts

Mental health has been in the news quite a bit lately. Dozens of U.S. states are currently suing Meta for contributing to the youth mental health crisis by inserting addictive features into their products, while the U.S. Surgeon General is touring the nation to bring awareness to the growing epidemic of loneliness and isolation. The country has endured periods of low national morale, such as in the 1970s when high inflation and the energy crisis worsened public sentiment following the Vietnam War. The current mood, however, feels different. Gallup recently reported that national mental health is at an all-time low, with few bright spots to lift spirits. To better understand how Americans are feeling and their attitudes towards mental health in general, ThinkNow conducted a nationally representative quantitative survey of 1,500 respondents and found some interesting differences among ethnic, age and gender groups. Technology For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did. While technology has helped us keep in touch with friends and family in faraway places, it appears to have degraded our ability to connect in person. Staying connected online is a double-edged sword since the same news feed that brings us pictures of the grandkids and fluffy kittens also feeds us news about the wars in Israel and Ukraine, the dysfunction in Washington, the latest mass shooting and the climate crisis. Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad. Age and Gender When asked how individuals rate their mental health, men rate it higher than women by 11 percentage points, and Baby Boomers rank it highest at 83%, saying it’s good or excellent vs. 57% of Gen Z saying the same. Gen Z spends the most amount of time on social media, so the notion that social media negatively affects mental health appears to be correlated. Unfortunately, Gen Z is also the generation that’s least comfortable discussing mental health concerns with healthcare professionals. Only 40% of them state they’re comfortable discussing their issues with a professional compared to 60% of Millennials and 65% of Boomers. Race Affects Attitudes As seen in previous research conducted by ThinkNow, Asian Americans lag other groups when it comes to awareness of mental health issues. Twenty-four percent of Asian Americans believe that having a mental health issue is a sign of weakness compared to the 16% average for all groups. Asians are also considerably less likely to be aware of mental health services in their communities (42% vs. 55%) and most likely to seek out information on social media (51% vs. 35%).

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A report by thenetworkone and Kurio. The contributing experts and agencies are (in an alphabetical order): Sylwia Rytel, Social Media Supervisor, 180heartbeats + JUNG v MATT (PL), Sharlene Jenner, Vice President - Director of Engagement Strategy, Abelson Taylor (USA), Alex Casanovas, Digital Director, Atrevia (ES), Dora Beilin, Senior Social Strategist, Barrett Hoffher (USA), Min Seo, Campaign Director, Brand New Agency (KR), Deshé M. Gully, Associate Strategist, Day One Agency (USA), Francesca Trevisan, Strategist, Different (IT), Trevor Crossman, CX and Digital Transformation Director; Olivia Hussey, Strategic Planner; Simi Srinarula, Social Media Manager, The Hallway (AUS), James Hebbert, Managing Director, Hylink (CN / UK), Mundy Álvarez, Planning Director; Pedro Rojas, Social Media Manager; Pancho González, CCO, Inbrax (CH), Oana Oprea, Head of Digital Planning, Jam Session Agency (RO), Amy Bottrill, Social Account Director, Launch (UK), Gaby Arriaga, Founder, Leonardo1452 (MX), Shantesh S Row, Creative Director, Liwa (UAE), Rajesh Mehta, Chief Strategy Officer; Dhruv Gaur, Digital Planning Lead; Leonie Mergulhao, Account Supervisor - Social Media & PR, Medulla (IN), Aurelija Plioplytė, Head of Digital & Social, Not Perfect (LI), Daiana Khaidargaliyeva, Account Manager, Osaka Labs (UK / USA), Stefanie Söhnchen, Vice President Digital, PIABO Communications (DE), Elisabeth Winiartati, Managing Consultant, Head of Global Integrated Communications; Lydia Aprina, Account Manager, Integrated Marketing and Communications; Nita Prabowo, Account Manager, Integrated Marketing and Communications; Okhi, Web Developer, PNTR Group (ID), Kei Obusan, Insights Director; Daffi Ranandi, Insights Manager, Radarr (SG), Gautam Reghunath, Co-founder & CEO, Talented (IN), Donagh Humphreys, Head of Social and Digital Innovation, THINKHOUSE (IRE), Sarah Yim, Strategy Director, Zulu Alpha Kilo (CA).

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The search marketing landscape is evolving rapidly with new technologies, and professionals, like you, rely on innovative paid search strategies to meet changing demands. It’s important that you’re ready to implement new strategies in 2024. Check this out and learn the top trends in paid search advertising that are expected to gain traction, so you can drive higher ROI more efficiently in 2024. You’ll learn: - The latest trends in AI and automation, and what this means for an evolving paid search ecosystem. - New developments in privacy and data regulation. - Emerging ad formats that are expected to make an impact next year. Watch Sreekant Lanka from iQuanti and Irina Klein from OneMain Financial as they dive into the future of paid search and explore the trends, strategies, and technologies that will shape the search marketing landscape. If you’re looking to assess your paid search strategy and design an industry-aligned plan for 2024, then this webinar is for you.

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From their humble beginnings in 1984, TED has grown into the world’s most powerful amplifier for speakers and thought-leaders to share their ideas. They have over 2,400 filmed talks (not including the 30,000+ TEDx videos) freely available online, and have hosted over 17,500 events around the world. With over one billion views in a year, it’s no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively. The article “5 Public-Speaking Tips TED Gives Its Speakers”, by Carmine Gallo for Forbes, gives speakers five practical ways to connect with their audience, and effectively share their ideas on stage. Whether you are gearing up to get on a TED stage yourself, or just want to master the skills that so many of their speakers possess, these tips and quotes from Chris Anderson, the TED Talks Curator, will encourage you to make the most impactful impression on your audience. See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers See the original article on Forbes here: http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9b

5 Public speaking tips from TED - Visualized summary

SpeakerHub

Everyone is in agreement that ChatGPT (and other generative AI tools) will shape the future of work. Yet there is little consensus on exactly how, when, and to what extent this technology will change our world. Businesses that extract maximum value from ChatGPT will use it as a collaborative tool for everything from brainstorming to technical maintenance. For individuals, now is the time to pinpoint the skills the future professional will need to thrive in the AI age. Check out this presentation to understand what ChatGPT is, how it will shape the future of work, and how you can prepare to take advantage.

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Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...

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During this webinar, Anand Bagmar demonstrates how AI tools such as ChatGPT can be applied to various stages of the software development life cycle (SDLC) using an eCommerce application case study. Find the on-demand recording and more info at https://applitools.info/b59 Key takeaways: • Learn how to use ChatGPT to add AI power to your testing and test automation • Understand the limitations of the technology and where human expertise is crucial • Gain insight into different AI-based tools • Adopt AI-based tools to stay relevant and optimize work for developers and testers * ChatGPT and OpenAI belong to OpenAI, L.L.C.

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