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End-Tidal CO2
(EtCO2)

The Wave Of The Future
EtCO2 Basics
EtCO2 measures ventilation

SAo2 measures oxygenation

Uses infra-red light to measure exhaled air

Vacuum in LP15 draws 50mL/min
EtCO2 Basics
Tachypnea - abnormally rapid breathing

Hyperventilation - Increased minute
ventilation that results in decreased EtCO2
levels (hypocapnea)

Hypoventilation - Decreased minute
ventilation that results in increased EtCO2
levels (hypercapnea)
Cellular Ventilation
Alveolar Ventilation
EtCO2 Basics
EtCO2 monitoring is continuous - changes
are immediately seen (CO2 diffuses across
membranes < 0.5 sec)

SAo2 monitoring relies on trending
EtCO2 Basics
Normal Values 35-45mmHg



<35 = hyperventilation

decreased metabolic state





>45 = hypoventilation

increased metabolic state
EtCO2 Basics
< 35mmHg (Hyperventilation)



Increased CO2 clearance (tachypnea)



Decreased CO2 production

(hypothermia, sedation, paralysis)



Decreased delivery to lungs

(decreased cardiac output)



V/Q mismatch (ventilating non-perfused

lungs - Pulmonary embolism)
EtCO2 Basics
> 45mmHg (Hypoventilation)



Decreased central drive, muscle

weakness, diffusion problems



Increased CO2 production

(Fever, burns, Hyperthyroidism, sz,

Bicarb, ROSC, reperfusion)
EtCO2 Basics
Normal Capnogram















EtCO2 Basics
Baseline - CO2-free air in dead spaces















EtCO2 Basics
Expiratory Upstroke (exhalation)













EtCO2 Basics
Expiratory plateau (exhalation of mostly
alveolar gases)













EtCO2 Basics
Inspiration (inhalation of CO2-free gases)















Bronchospasm
Normal Bronchospasm

(Uneven alveolar emptying)
Emphysema
Pulmonary Edema
Poor Plateau
Differential Lung
Emptying
Curare Cleft
Carbonated Beverages
Esophageal Intubation
Ineffective Respirations
Pain Management/
Sedation
Hypothermia/

Low Metabolic Demand
Malignant Hyperthermia
Metabolic States
Diabetes/Dehydration

EtCO2 tracks serum HCO3 & degree of acidosis

↓EtCO2 = metabolic acidosis

















Metabolic States
Sepsis

EtCO2 inversely related to Lactate

The lower the EtCO2, the higher the
lactate levels

Lactate levels >4 = sepsis

EtCO2 levels <25 = sepsis alert
Cardiac Output
Cardiac
CHF/Heart Failure
Cardiac Arrest

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