Significance and sources of pantothenic acid

1. Significance and sources of
pantothenic acid
Domina Petric, MD

2. Significance
• Pantothenic acid is widely
distributed in many foods.
• Problems of deficiency of the
vitamin are rare.
• The vitamin has critical roles in
metabolism, being an integral part of
the acylation factors coenzyme-A
(CoA) and acyl-carrier protein (ACP).
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
2

3. Significance
Pantothenic acid is required for the
normal metabolism of fatty acids,
amino acids and carbohydrates.
It has important roles in the
acylation of proteins.
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
3

4. Distribution in foods
Pantothenic acid is widely
distributed in nature.
It occurs mainly in bound
forms: CoA, CoA esters, acyl-
carrier protein.
A glycoside has been
identified in tomatoes.
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
4

5. Diary products and other
Diary products Pantothenic acid mg/100 g
Milk 0,2
Cheeses 0,1-0,9
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
5
Other Pantothenic acid mg/100 g
Eggs 2,9
Mushrooms 2,1
Bakers´ yeast 5,3-11

6. Meats
Meat Pantothenic acid mg/100 g
Beef 0,3-2,0
Pork 0,4-3,1
Calf heart 2,5
Calf kidney 3,9
Chicken liver 9,7
Pork liver 7,0
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
6

7. Cereals
Cereal Pantothenic acid mg/100 g
Cornmeal 0,9
Unpolished rice 1,1
Oatmeal 0,9
Wheat 1,0
Wheat bran 2,9
Barley 1,1
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
7

8. Vegetables
Vegetable Pantothenic acid mg/100 g
Avocado 1,1
Broccoli 1,2
Cabbage 0,1-1,4
Carrots 0,27
Cauliflower 1,0
Lentils 1,4
Potatoes 0,3
Soybeans 1,7
Tomatoes 0,3
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
8

9. Fruits
Fruit Pantothenic acid mg/100 g
Apples 0,1
Bananas 0,2
Grapefruits 0,3
Oranges 0,2
Strawberries 0,3
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
9

10. Nuts
Nut Pantothenic acid mg/100 g
Walnuts 0,7
Cashews 1,3
Peanuts 2,8
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
10

11. Stability
• Pantothenic acid in foods and
feedstuffs is fairly stable to ordinary
means of cooking and storage.
• It can be unstable to heat and either
alkaline (pH>7) or acid (pH<5)
conditions.
• Reports indicate losses of 15 to 50%
from cooking meat and of 37 to 78%
from heat-processing vegetables.
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
11

12. Stability
The alcohol derivative,
pantothenol, is more stable.
It is used as a source of the
vitamin in multivitamin
supplements.
April 17, 2018
Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
12

13. Literature
• Combs GF. The Vitamins. Fundamental Aspects in
Nutrition and Health. Elsevier Inc. 2008.
April 17, 2018 13