Neutraceuticals products have very big share in today's market. This presentation briefs about basic nutrients that are used as neutraceuticals

1. Nutraceutical
products
used in the treatment of diseases

2. Lifestyle
Disorders

3. Consumption of junk food has increased manifold, which has led to a
number of diseases related to nutritional deficiencies.

4. The term was coined by Stephen Defelice
According to him “a nutraceutical is any substance that is a food or a part
of food and provides medical or health benefits, including the prevention
and treatment of disease”.
plays an important role

5. The nutraceutical industry is growing at a rate far exceeding expansio
n in the food and pharmaceutical industries.

6. The nutraceutical industry is growing at a rate far exceeding expansio
n in the food and pharmaceutical industries.
Here the focus is on optimizing or fine-tuning normal dietary components to
provide the best health or functional outcomes.
Typically the products revolve around the levels of
• micronutrients (vitamins, minerals) and
• macronutrients (proteins, lipids, carbohydrates)
that need to be consumed in order to alleviate or prevent deficiencies as w
ell as improving the quality of particularly macronutrients to exert certain heal
th benefits
Examples of this approach are
• Supplementation or fortification products with vitamins and Minerals,‘
• Light products with less sugar or fat,
• Alternative energy sources,
• claims related to the health impact of lipids from different omega families

7. Health claims of food and nutraceuticals are not permitted to claim the
treatment, cure, diagnosis, or mitigation of disease

8. A vitamin is an organic molecule (or related set of molecules)
that is an essential micronutrient that an organism needs in s
mall quantities for the proper functioning of its metabolism

9. A very old example is the introduction of high dose oral folate therapy
as an alternative to vitamin B12 in treating pernicious anaemia in the
1930s. An issue that is still unresolved and reflected in divergent public
health policy is the fortification of flour with folate, done in the USA
with probable benefit in terms of reduced neonatal neural tube
defects, but not in the UK

10. Vitamin A deficiency symptoms include:
• Night blindness (early) leading to full blindness
• Dry eyes, skin, and other tissue
• Increased infections
• Thinning and ulceration of the cornea
• Oval, triangular, or irregular foamy patches on the white of t
he eye[
• Dry hair
• Pruritis
• Broken fingernails
Food sources of vitamin A include:
• Carrots
• Dark leafy greens
• Mango
• Sweet potatoes
• Tuna

12. Vitamin C is credited with boosting immunity, but that’s not all it
does. It helps heal wounds; repairs cartilage, bones, and teeth; an
d is an antioxidant
Sorses
Broccoli
Oranges
Grapefruit
Cantaloupe
Cauliflower
Kiwi fruit
Leafy greens
Mango
Papaya
Peppers, green and red
Pineapple
Potatoes (sweet and white)

13. Vitamin D deficiency symptoms include:
• osteomalacia (or rickets when it occurs in children)
• impaired bone mineralization and bone damage

14. Dietary fibre is the food material, more precisely the plant material
that is not hydrolyzed by enzymes secreted by the digestive tract,
but digested by microflora in the gut.
Persons consuming generous amounts of dietary fibre, compared t
o those who have minimal fibre intake, are
having low risk of CHR ,
stroke
Hypertension
diabetes
obesity and
certain gastrointestinal disorders
Again, increase in the intake of high fibre food improves
serum lipoprotein values
lowers blood pressure level

15. PUFAs are also called “essential fatty acids” as these are
crucial to the body’s function and are introduced externally
through the diet
omega-3
omega-6
Studies suggest that omega-3-fatty acids have three
major effects as cardiovascular diseases0
anti-arrhythmic
and antithrombotic
FDA recommends a maximum of 3 g/day intake of EPA and
DHA omega-3 fatty acids, with no more than 2 g per
day from a dietary supplement

16. A probiotic can be defined as live microbial feed supplement,
which when administered in adequate amounts beneficially affe
cts the host animal by improving its intestinal microbial balance.
Specific probiotics are generally used to treat gastrointestinal
conditions such as
• Lactose intolerance,
• Acute diarrhea and
• Antibioticassociated GI side effects

17. Prebiotics are dietary ingredients that beneficially affect the host
by selectively altering the composition or metabolism of the gut
microbiota
These are short-chain polysaccharides that have unique chemical
structures that are not digested by humans; in particular fructose-
based oligosaccharides that exist naturally in food or are added
in the food
The prebiotic consumption generally promotes the Lactobacillus a
nd Bifidobacterial growth in the gut, thus helping in metabolism
Sources:

18. Selenium is an essential trace element that is involved in the
defense against the toxicity of reactive oxygen species, the regulat
ion of the redox state of cells and in the regulation of thyroid
hormone metabolism.
Its deficiency has caused serious health effects in human, such as
Keshan’s disease, a potentially fatal form of cardiomyopathy, that
affects young women and child.
Sourses:

19. Polyphenols form a large group of phytochemicals, which are
produced by plants as secondary metabolites to protect them
from photosynthetic stress, reactive oxygen species.
There are approximately 8,000 different classes of polyphenols,
the most important being
• flavonols,
• flavones,
• flavan-3-ols,
• flavanones and
• anthocyanins.
Polyphenols are mostly acknowledged for their antioxidant
activities
Tea (Camellia sinensis) is a rich source of polyphenols, such as
catechins.
Tea also constitutes of flavonols like quercetin and myricetin. T
ea, mainly consumed in the form of black tea and green tea h
as been found to have cancer-preventing activities

20. Legumes are consumed worldwide as an alternative source of
proteins, since they are rich in amino acids like lysine and trypt
ophan and they are much cheaper than animal proteins.
Studies have revealed that in addition to complex carbohydrat
es, soluble fibers, essential vitamins, and metals, legumes also
supply the diet with polyphenols like flavonoids, isoflavones an
d lignans. Of all legumes, soyabean has received most attentio
n. Soyabe n is most significant source of dietary isoflavones.

21. Spices are esoteric food adjuncts that are used for thousands of
years to enhance the sensory quality of foods.
These impart characteristic flavor, aroma, or piquancy and colour
to foods, stimulating our appetite as well as modify the texture of
food

24. I express Deepest gratitute to Dr. Abhay Dharamsi for providing such an opp
ortunity.
I heartily thank Dr. Falguni Tandel for always entrusting me.
I thank Gujarat State Pharmacy Council for sponsoring the event.