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biochemistry chapter 1.pdf
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Biochemistry And Clinical Pathology Chapter 1
Introduction To Biochemistry
Introduction To Biochemistry
The Word Biochemistry is formed by Bio means living , and chemistry means chemical
reaction or chemical molecule .
so we can say:
Biochemistry is a branch of science in which we study about chemical reaction or
biomolecule inside the living organism .
Biomolecules
The cell of living organism is composed of a few elements like C , H, O ,and N etc. are
called biomolecules .
More than 10,000 or 100,000 biomolecules are present in human body but some them
recognised . example
1) amino acids 2) monosaccharide 3) nucleotide
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Scope Of Biochemistry In Pharmacy
1) Drug Formulation : The biochemistry helps in drug formulation .
2) Drug Improvement : The biochemistry helps in the improvement of drug .
3) half Life : The biochemistry helps to know the half life of a drug , and biochemical test
is performed to check how long a drug is stable on a given temperature .
4) Drug Storage : The storage condition required for a drug is estimated by biochemical
test .
5) Expiry : The biochemistry helps to know the expiry of a drug .
Cell and Its biochemical organisation
Cell
Cell is the smallest structural and functional unit of living organism , About 100 trillion
cells are found in a normal human being .
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Biochemical organisation of Cell
As the tissues are made up of cells , in the same way cells are made up of molecules (
biomolecules ) . In other words we can say as cells are building blocks of tissues ,
biomolecules are building blocks of cells .
Biomolecules
Biomolecules are those elements( like C,H, O , N) which make different type of
chemical compounds and structures .
More than 10,000 or 100,000 biomolecules are present in human body but some them
recognised .
when different small organic compounds like amino acids , monosaccharide ,
nucleotides get together and form chemical compounds or structures called complex
Biomolecules , major complexx biomolecules are following
1) Carbohydrate 2) Protein 3) lipids 4) Nucleic Acid
Biomolecules Building Blocks Major Functions
Protein Amino acids Form basic frame work of cell
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DNA Deoxyribonucleotides Carry the genetic material
RNA Ribonucleotides Carry information for protein
synthesis
Carbohydrates Monosaccharide It stored in the form of glycogen and
fulfill short term energy requirement
Lipids Fatty acids glycerol It is second major source of energy
and fulfill long term requirement .
Micromolecules
Macromolecules