1. The document is a material safety data sheet for Niax® silicone L-540, which is used in polyurethane foam manufacturing.
2. It contains polyalkylene glycol, polyalkyleneoxidemethylsiloxane copolymer, polyalkylene glycol, and octamethylcyclotetrasiloxane.
3. The product may cause eye irritation and contains a component that may cause reproductive effects based on animal data. Proper personal protective equipment should be used when handling.
Mattingly "AI & Prompt Design: The Basics of Prompt Design"
Msds l 540
1. MATERIAL SAFETY DATA SHEET
Revision: 1.0
2006.06.23
Page: 1 of 8
Product name: Niax® silicone L-540
1. PRODUCT AND COMPANY IDENTIFICATION
Product name: Niax® silicone L-540
Chemical name: Polyalkyleneoxidemethylsiloxane copolymer
Use(s): Used in polyurethane foam manufacturing.
Supplier: GE Canada
1063 Copperstone Drive
Pickering, Ontario L1W 3V8, Canada
Manufacturer: GE Silicones
3500 South State Route 2
Friendly, WV 26146, USA
Prepared by/For MSDS, Product Product Safety Department
Safety, or regulatory inquiries, call: 304-652-8446 or 304-652-8155
Issue date: 2006.06.23
Emergency telephone number: CANUTEC (24 hours) 613-996-6666
2. COMPOSITION / INFORMATION ON INGREDIENTS
COMPONENT CAS# %W/W
Polyalkylene glycol- WHMIS Non-Haz Trade secret 30.0 - 60.0 %
Polyalkyleneoxidemethylsiloxane copolymer-WHMIS- Trade secret 30.0 - 60.0 %
Non-Haz
Polyalkylene glycol-WHMIS-Non-Haz Trade secret 7.0 - 13.0 %
Octamethylcyclotetrasiloxane 556-67-2 0.1 - 0.5 %
3. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
WARNING!
MAY CAUSE EYE IRRITATION.
CONTAINS OCTAMETHYLCYCLOTETRASILOXANE WHICH MAY CAUSE REPRODUCTIVE EFFECTS
BASED ON ANIMAL DATA.
2. MATERIAL SAFETY DATA SHEET
Revision: 1.0
2006.06.23
Page: 2 of 8
Product name: Niax® silicone L-540
4. FIRST AID MEASURES
Swallowing
Give water to drink. Obtain medical attention.
Skin
Remove contaminated clothing. Wash skin with soap and water. Obtain medical attention if discomfort persists.
Inhalation
Remove to fresh air. Obtain medical attention.
Notes to physician
There is no specific antidote. Treatment of overexposure should be directed at the control of symptoms and the
clinical condition of the patient.
5. FIRE-FIGHTING MEASURES
Flash point: 103 °C
Flammable limits
Lower limit: Not available
Upper limit: Not available
Hazardous combustion products
Burning can produce the following combustion products:
Oxides of carbon.
Oxides of silicon.
Carbon monoxide is highly toxic if inhaled; carbon dioxide in sufficient concentrations can act as an asphyxiant.
Acute overexposure to the products of combustion may result in irritation of the respiratory tract.
Special fire fighting procedures
Do not direct a solid stream of water or foam into hot, burning pools: this may cause frothing and increase fire
intensity.
Special protective equipment for firefighters
Self-contained breathing apparatus. Body covering protective clothing.
Extinguishing media
Suitable: Large fires:
- alcohol-type foam or universal-type foams
Small fires:
- CO2
- dry chemical
Unsuitable: None.
Unusual fire and explosion hazards
None known.
3. MATERIAL SAFETY DATA SHEET
Revision: 1.0
2006.06.23
Page: 3 of 8
Product name: Niax® silicone L-540
6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Avoid contact with eyes and skin. Avoid contact with liquid and vapors. Wear suitable protective equipment.
Environmental precautions
Prevent runoff.
Methods for cleaning up
Cover with absorbent or contain.
Collect for disposal.
Observe government regulations.
7. HANDLING AND STORAGE
HANDLING
Handling precautions
Do not swallow. Do not get in eyes, on skin, on clothing. Avoid breathing vapor, aerosol and mist. Use with
adequate ventilation. Wash thoroughly after handling.
STORAGE
Storage requirements
Keep away from heat and flame. Keep container closed.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
PERSONAL PROTECTION
Respiratory protection
Self-contained breathing apparatus in high vapor concentrations.
Hand protection / protective gloves
Recommended order of use:
4H
Butyl
Neoprene
Nitrile (NBR)
PVC-coated
Eye protection
Monogoggles
Skin protection
Chemical protective clothing.
4. MATERIAL SAFETY DATA SHEET
Revision: 1.0
2006.06.23
Page: 4 of 8
Product name: Niax® silicone L-540
Other protective equipment
Eye bath
Safety shower
ENGINEERING CONTROLS
Ventilation
General mechanical room ventilation is satisfactory for normal handling and storage operations.
Special, local ventilation is needed at points where vapors can be expected to escape to the workplace air.
EXPOSURE LIMITS
Component Type Value Remark
Octamethylcyclotetrasil TWA, Internal Exposure 5.0 ppm
oxane Limit
Consult local authorities for acceptable provincial values.
9. PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Physical state Liquid
Color Clear, pale
Odor Polyether
Odor threshold No data available.
OTHER PROPERTIES
Boiling point > 150 °C at STP unless specified below.
Copolymer
Melting point < 0 °C at STP unless specified below.
pH Not available
Specific gravity (H2O=1) 1.0300 at 25 °C ( 1,013 hPa)
Vapor pressure < 1.33 hPa (1.00 mmHg) at 20 °C
Vapor density (air=1) Heavier than air
Solubility in water Soluble
Evaporation rate (Butyl <1
Acetate=1)
Partitioning coefficient No data available.
Flash point 103 °C
Method: Pensky-Martens closed cup ASTM D 93
Percent volatiles Not determined
5. MATERIAL SAFETY DATA SHEET
Revision: 1.0
2006.06.23
Page: 5 of 8
Product name: Niax® silicone L-540
Molecular weight Copolymer
10. STABILITY AND REACTIVITY
Stability: Stable.
Stability - Conditions to avoid
None known.
Incompatible materials
None currently known.
Hazardous polymerization: Will not occur.
Hazardous polymerization - Conditions to avoid
None known.
11. TOXICOLOGICAL INFORMATION
SWALLOWING
Acute effects
May cause the following effects:
- abdominal discomfort
- nausea
- vomiting
May affect the gastrointestinal and respiratory systems, kidneys, liver, heart,|and cause severe CNS depression and
death. Lung damage may result from accidental aspiration.
Long-term oral exposure affected the brain, heart, liver, kidney, and bladder in laboratory animals.
SKIN ABSORPTION
Acute effects
No evidence of harmful effects from available information.
INHALATION
Acute effects
Short-term harmful health effects are not expected from vapor generated at ambient temperature.
An ingredient in the controlled product has a major effect on the CNS, causing initial excitation (tremors, increased
locomotor activity) followed by depression (incoordination, narcosis, anaesthesia). Acute exposure affects behaviour,
performance, sleep cycle, the respiratory and cardiovascular systems and kidneys.
An ingredient in the controlled product is a respiratory irritant, a CNS depressant and anaesthetic, causing headache,
dizziness, acute behavioral effects (hilarity, irritability, confusion), impaired reaction time, poor coordination, visual
disturbances, collapse, death as well as reversible kidney and liver damage.||Lethal cardiac irregularities may occur in
predisposed individuals.
Chronic exposure causes inflammation and degeneration of the respiratory lining, permanent hearing loss, behavioral
changes and decreased learning and toxic changes in the optic nerve in experimental animals.
CNS disturbances (headache, dizziness, abnormal gait, tremors, memory loss, incoordination), reduced dexterity,
reduced ability to concentrate have been reported following long-term occupational exposure to an ingredient in the
controlled product which may have involved simultaneous exposure to other solvents. An extensive review of
available data suggests there may be peripheral nerve effects (paraesthesia, reduced conduction velocity), hearing
6. MATERIAL SAFETY DATA SHEET
Revision: 1.0
2006.06.23
Page: 6 of 8
Product name: Niax® silicone L-540
damage and reversible liver and kidney damage, abnormal numbers of blood cells, but that no completely adequate
studies are available.
SKIN CONTACT
Acute effects
In experimental animals, an ingredient in the controlled product causes damage to the upper skin layers within 15
minutes, which may extend into the lower skin layers within an hour.
May cause skin damage due to degreasing action.
Prolonged contact may result in:
- drying of the skin
- defatting of the skin
- development of fissures
- dermatitis
EYE CONTACT
Acute effects
Causes irritation.
Causes the following effects:
- stinging
- discomfort
- pain
May cause the following effects:
- excess redness of the conjunctivae
- swelling of the conjunctivae
Medical conditions aggravated by exposure
A knowledge of the available toxicology information and of the physical and chemical properties of the material
suggests that overexposure is unlikely to aggravate existing medical conditions.
Other effects of exposure
Solvents such as benzene and chlorinated hydrocarbons are toxicologically synergistic products in combination with
an ingredient in the controlled product.
SIGNIFICANT DATA WITH POSSIBLE RELEVANCE TO HUMAN HEALTH
The following information is based on analogy with a similar material:
This material was negative in a Salmonella Typhimurium/ Escherichia coli mutagenicity assay.
Octamethylcyclotetrasiloxane:
Repeated exposure to octamethylcyclotetrasiloxane by inhalation (300 ppm) or by the oral route in rodents produced
increased liver weight, which was generally reversible after exposure ceased. Repeated exposure by inhalation in
pregnant rats (700 ppm) did not produce any developmental effects, but certain reproductive parameters (reduction in
mean live litter size, and implantation sites) were affected.
The relevance of these data to humans is unclear. Further studies are on-going.
Octamethylcyclotetrasiloxane was not clastogenic in an in-vivo bone marrow chromosomal assay in Sprague Dawley
rats following inhalation of vapor.
A 2 yr. combined chronic/carcinogenicity assay was conducted on octamethylcyclotetrasiloxane (D4). Fischer-344
rats were exposed by whole-body vapor inhalation 6 hrs/day, 5 days/week for up to 104 weeks to 0, 10, 30, 150 or
700 ppm of D4. A statistically significant increase in incidence of (uterine) endometrial cell hyperplasia and uterine
adenomas (benign tumors) were observed in female rats at 700 ppm. Since these effects only occurred at 700 ppm, a
level that greatly exceeds typical workplace or consumer exposure, it is unlikely that industrial, commercial or
consumer uses of products containing D4 would result in a significant risk to humans.
7. MATERIAL SAFETY DATA SHEET
Revision: 1.0
2006.06.23
Page: 7 of 8
Product name: Niax® silicone L-540
12. ECOLOGICAL INFORMATION
All available ecological data have been taken into account for the development of the hazard and precautionary
information contained in this Material Safety Data Sheet.
13. DISPOSAL CONSIDERATIONS
General: Incinerate in a furnace where permitted under appropriate federal, provincial, and local
regulations.
14. TRANSPORT INFORMATION
TDG - Canada
This product is not regulated by TDG.
IMDG Classification
This product is not regulated by IMDG.
ICAO Classification
This product is not regulated by ICAO.
15. REGULATORY INFORMATION
WHMIS CLASSIFICATION
D2A Very toxic material causing other effects.
CPR Compliance
This product has been classified with the hazard criteria of the CPR, and the MSDS contains all the information
required by CPR.
CHEMICAL INVENTORY
Canada: The ingredients of this product are on the DSL.
Europe: The ingredients of this mixture are on the EINECS inventory.
United States: The ingredients of this product are listed on the TSCA inventory or are exempt.
Australia: This product, or the components, is listed or exempt from listing on the Australian
Inventory of Chemical Substances (AICS).
Japan: This product, or the components, is listed or exempt from listing on the Existing and New
Chemical Substances (ENCS) list.
Korea: This product is listed on the Existing Chemicals List (ECL).
Philippines: This product, or the components, is listed or exempt from listing on the Philippines
Inventory of Chemicals and Chemical Substances (PICCS).
8. MATERIAL SAFETY DATA SHEET
Revision: 1.0
2006.06.23
Page: 8 of 8
Product name: Niax® silicone L-540
16. OTHER INFORMATION
RECOMMENDED USES AND RESTRICTIONS
Please consult the product and/or application information bulletins for this product.
LEGEND
STP Standard temperature and pressure
W/W Weight/Weight
The opinions expressed herein are those of qualified experts within GE Silicones. We believe that the information
contained herein is current as of the date of this Safety Data Sheet. Since the use of this information and of these
opinions and the conditions of use of this product are not within the control of GE Silicones, it is the user's obligation
to determine the conditions of safe use of the products.