Iron absorption

1. Absorption of Iron
• the iron absorb in small intestine mucosa mainly
in duodenum.
• the acidic ph of stomach favours the absorption.
• Iron is mostly found in ferris form (fe+++).
• The ferric ions are reduced by ascorbic acid and
glutathione of food to more

2. • Soluble ferrou (fe++)from wich is ir wich is more
readily absorbed

3. Transporting:-

4. • The iron(fe++) entering the mucosa cell by
absorption is oxidized to ferric form by
• enzyme ferroxidase .
• the (Fe+++) combines with apoferritin to form
ferritin wich the temporary storage form of iron.

5. • From mucosa cells iron may entering the blood
stream.
• Iron enters plasma in ferrous state its oxidized
to fferric form by copper containing protein
ceruloplasimin ,ferroxidase activity.

6. • Ferric iron binds with specific iron binding
protein t( transferrin) is aglycoprotein synthesized
in liver.
• one molecules of transferrin can transport two
ferric aotms

7. • factor affecting iron absorption :
• 1_ increasing
• In effective erthropoesis
• Iron deficence
• 2_decreasing:-
• gastrointestinal deases

8. Iron storge
• Liver
• Spleen
• bone marrow
• Intestine

9. Excretion:-
faeces
urine
Menstruation