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*Corresponding Author: S Parvej, Email: s.parvej.solanki@gmail.com
RESEARCH ARTICLE
ISSN 0976 – 3333
REVIEW ARTICLE
Available Online at www.ijpba.info
International Journal of Pharmaceutical & Biological Archives 2016; 8 (1): 10-12
Mimosa hamata Willd. : A Review on Ethnobotanical, Phytochemical and
Pharmacological Profile
S Parvej*, Kumkum Mathur, M Goyal, S K Yadav
Department of Pharmacology, Lachoo Memorial College of Science and Technology, Pharmacy wing
Autonomous, Jodhpur (Raj)
Received 28 Nov 2016; Revised 05 Feb 2016; Accepted 14 Feb 2016
ABSTRACT
Mimosa hamata willd. is a flowering shrub of Mimosacae family which is used in various traditional
medicines to cure various diseases. Mimosa hamata willd. and Mimosa pudica are also known as Touch-
me-not plant. This weed have been known to posses anti asthmatic, wound-healing, analgesic, anti-
inflammatory, contraceptive, anti-microbial, anti-viral, anti-fungal, antioxidant, anti-diarrheal blood-
purifier and contraceptive properties in ancient literatures. A wide range of chemical compounds
including 4-ethyl-gallic acid, triterpinic saponin A, B, ethylgallate, mimonoside A, B, C, etc have been
isolated from this plant. Present review summarizes the information concerning botany,
ethnopharmacology, phytochemistry, biological activity of Mimosa hamata willd.
Keywords: Mimosa hamata willd, Ethnopharmacology, Phytochemistry, Pharmacological activities
INTRODUCTION
Mimosa hamata willd. (Fig.1)(Family mimosacae)
(Genus Mimosa) commonly known as Alai is a
flowering shrub of pea family and is native to arid
regions of Indian subcontinent.
Fig 1: A picture of Mimosa hamata willd.
Taxonomical classification
Table 1: Taxonomical classification of Mimosa hamata willd
Kingdom: Plantae
Order: Fabales
Family: Fabaceae
Genus: Mimosa
Species: M. hamata
Vernacular names
Common Names - Hooked Mimosa
• Hindi - Mundi, Bander-ki-Rakhi
• Marathi- Gulabi babul
• Telugu- Undrakampa
Botanical name: Mimosa hamata
Family: Mimosaceae (Touch-me-not)
Synonyms: Mimosa armata
Plant description
The plant is branched and is thicket
forming, height is around 1.5 meter.
• Roots are brown in colour.
• Stem is cylindrical in shape with brown
branches, the branches posses pinkish stiff
spines which are generally straight or
curved near apex, young branches with
longitudinal ribs and downy with dense
growth of small hairs are present.
• Leaves are alternate, stipulate, compound,
bipinnate, 1.5 to 2.5 cm with rachis
densely covered with hairs with 2-4 small
curved spines on its abaxial surface.
• Leaflets are present 5 to 9 pairs, ovate,
oblong, tip acute or mucronate, glabrous
on the adaxial surface but densely
pubescent beneath, rounded but oblique at
base.
Parvej et al. Mimosa Hamata Willd. : A Review On Ethnobotanical, Phytochemical And Pharmacological Profile
11
© 2010, IJPBA. All Rights Reserved.
• Inflorescence: globose head born in the
axil of leaves, mostly crowded near the
distal ends of young branches.
• Flowers are sessile pinkish, tetramerous,
actinomorphic.
• Calyx are 2 mm long, divided nearly half
way down.
• Corolla are lobed, ovate-oblong and acute.
• Stamens are pink, anther-lobed, creamy
yellow, bithecous, basifixed.
• Gynoecium: monocarpellary, unilocular,
marginal placentation, superior, present on
a stalk, elongated, curved and pubescent.
• Stigmas are inconspicuous.
• Fruits are legume, falcate or spirally
coiled, one seeded.
• Seeds are oval, green when young turning
to chestnut brown on maturation.
• Flowering: July-October;
• Fruiting: August-November.
Phytoconstituents
All the plant parts (stem, leaves, flowers and
roots) of Mimosa hamata were investigated for the
chemical constituents. Therapeutically important
compounds isolated from M. hamata include 4-
ethylgallic acid from fresh flowers. [2]
, triterpene
saponin B (3-O-Larabinosyl-D-glucosyl morolic
acid), mimonoside A, B, C and saponin A (3-O-D-
glucosyl-L-rhamnosyl morolic acid) from the
roots [3], [4], [7]
, ethylgallate and gallic acid from
leaves [3]
Pharmacological activity
Antimicrobial activity
M. hamata willd. posses antimicrobial activity,
crude ethanolic extract of aerial part of Mimosa
hamata and deproteinized leaf extract showed
their inhibitory effect against microorganisms
such as bacteria and fungi. [5]
Antiviral activity
Ethanolic extract of aerial part of Mimosa hamata
posses antiviral activities against Herpes simplex,
Poliomylietes and Stomatitis. Petroleum ether and
chloroform extracts also exhibited potential effect
against V. Stomatitis and Herpes simplex. Studies
revealed that the bio efficacy of the extracts of
whole plant were more effective than the fractions
obtained from callus tissues. Methanolic extract of
roots were also reported for their antiviral
activities against Measles, Semliki forest, Herpes
simplex and Vesicular stomatitis.[3], [5], [6]
Antioxidant activity
Methanolic extracts of this plant was studied for
higher antioxidant activity and result was positive
with 6.5 μg ml-1
RC value and Comparison to the
dichloromethane extracts also revealed that extract
of leaves, stem, root and seeds of M. hamata have
antioxidant potential. [7, 8, 9]
Aphrodisiac activity
Mimosa hamata is also used as herbal aphrodisiac
for providing ameliorating effect on sexual
dysfunction but it has not been clinically
evaluated for its aphrodisiac activities. Many
herbal aphrodisiac plants have large gap between
traditional knowledge and pharmacological
evidence.
Tradition Claims
The plant is widely used as an anti asthmatic;
wound healing, analgesic, anti-inflammatory,
contraceptive, anti-microbial, anti-viral, anti
fungal, antioxidant, blood-purifier, anti-diarrheal
and contraceptive agent. Kanjar tribe in Rajasthan
use this plant for treatment of bronchitis and
diarrhea in children. In Maharashtra its leaves are
used for offering prayers to god for the good
health of new born. The plant is also used as
ornament among various tribes in Maharashtra.
DISCUSSION
Mimosa hamata is found in arid regions of india
and is easily seen in regions like thar desert. This
plant is used as fodder for goats and camels. The
plant is widely use as a traditional medicine in
various tribes from north to south in India. The
plant has its traditional use as anti-asthmatic,
wound-healing, analgesic, anti-inflammatory,
contraceptive, anti-microbial, anti-viral, anti
fungal, antioxidant, anti-diarrheal, blood-purifier
and contraceptive agent and is used by different
tribes and societies in India but very little
scientific research has been done on this plant till
now. Therefore there is need of scientific research
on M. hamata to evaluate traditional medicinal
use of this plant.
REFERENCE
1. Singh Renu, Jasrai Yogesh T (2010
Mimosa hamta willd, A plant with anti
pathogenic property, International Journal
of aromatic medicinal plants vol.no.2 no. 4
page no. 677-682(2249-4340).
2. Mehta, B.K., Sharma, S., Dubey, A. 1988.
4- ethylgallic acid from two Mimosa
IJPBA,
Jan-Feb,
2016,
Vol.
8,
Issue,
1
Parvej et al. Mimosa Hamata Willd. : A Review On Ethnobotanical, Phytochemical And Pharmacological Profile
12
© 2010, IJPBA. All Rights Reserved.
species, Phytochemistry, 27(9): 3004-
3005.
3. Jain, R., Arora, R. 1997. 3-O-L-
Arabinosyl-Dglucosyl morolic acid from
Mimosa hamata. Journal of Medicinal and
Aromatic Plant Sciences, 19: 22-23.
4. Jain, R., Arora, R., Jain, S.C. 1997b.
Saponins from the roots of Mimosa
hamata Willd. Indian Journal of
Chemistry, 36B: 61-64.
5. Mukadam, D.S., Balkhande, L.D.,
Umalkar, G.V. 1976. Antifungal activities
indeproteinized leaf extracts of weeds and
non-weeds. Indian Journal of
Microbiology, 16: 78.
6. Jain, S.C., Jain, R., Vlietinck, A.J. 2004. In
vivo and in vitro antimicrobial efficacy of
Mimosa hamata. Indian Journal of
Biotechnology,3: 271-273.
7. Jain, R., Arora, R., Alam, S., Jain, S.C.
1997a. Pharmacological evaluation of
Mimosa hamata roots. Fitoterapia, 68(4):
377-388.
8. Singh, S.C., Jain, R. 2009. Antioxidant
activity of some medicinally important
arid zone plants. Asian Journal of
Experimental Sciences, 23(1): 215-221.
9. Jain, S.C., Jain, R., Singh, R. 2009b.
Antioxidant activity of mimonosides
isolated from in vitro regenerated plants of
Mimosa hamata Willd. Indian Journal of
Plant Physiology, 14(2): 124-129.
10. Singh, R., Jain, S.C. 2009. Antioxidant
activity of some medicinally important
arid zone plants. Asian Journal of
Experimental Sciences, 23(1): 215-221.
11. Jain Renuka, Jain S.C. Studies (2014) on
Antimicrobial and Antioxidant Potentials
of Triterpenoidal Saponins from Mimosa
hamata Willd. International Journal of
Pharmaceutical and Phytopharmacological
Research (eIJPPR) SSN (Online) 2249-
6084 (Print) 2250-1029.
12. Ali, M.S., Azhar, I., Ahmad, F., Ahmad
V.U., Usman ghani R.U. 2001.
Antimicrobial screening of Mimoaceous
plants. Pharmaceutical Biology, 39(1): 43-
46.
IJPBA,
Jan-Feb,
2016,
Vol.
8,
Issue,
1

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3. S.Pervej final for publication.pdf

  • 1. *Corresponding Author: S Parvej, Email: s.parvej.solanki@gmail.com RESEARCH ARTICLE ISSN 0976 – 3333 REVIEW ARTICLE Available Online at www.ijpba.info International Journal of Pharmaceutical & Biological Archives 2016; 8 (1): 10-12 Mimosa hamata Willd. : A Review on Ethnobotanical, Phytochemical and Pharmacological Profile S Parvej*, Kumkum Mathur, M Goyal, S K Yadav Department of Pharmacology, Lachoo Memorial College of Science and Technology, Pharmacy wing Autonomous, Jodhpur (Raj) Received 28 Nov 2016; Revised 05 Feb 2016; Accepted 14 Feb 2016 ABSTRACT Mimosa hamata willd. is a flowering shrub of Mimosacae family which is used in various traditional medicines to cure various diseases. Mimosa hamata willd. and Mimosa pudica are also known as Touch- me-not plant. This weed have been known to posses anti asthmatic, wound-healing, analgesic, anti- inflammatory, contraceptive, anti-microbial, anti-viral, anti-fungal, antioxidant, anti-diarrheal blood- purifier and contraceptive properties in ancient literatures. A wide range of chemical compounds including 4-ethyl-gallic acid, triterpinic saponin A, B, ethylgallate, mimonoside A, B, C, etc have been isolated from this plant. Present review summarizes the information concerning botany, ethnopharmacology, phytochemistry, biological activity of Mimosa hamata willd. Keywords: Mimosa hamata willd, Ethnopharmacology, Phytochemistry, Pharmacological activities INTRODUCTION Mimosa hamata willd. (Fig.1)(Family mimosacae) (Genus Mimosa) commonly known as Alai is a flowering shrub of pea family and is native to arid regions of Indian subcontinent. Fig 1: A picture of Mimosa hamata willd. Taxonomical classification Table 1: Taxonomical classification of Mimosa hamata willd Kingdom: Plantae Order: Fabales Family: Fabaceae Genus: Mimosa Species: M. hamata Vernacular names Common Names - Hooked Mimosa • Hindi - Mundi, Bander-ki-Rakhi • Marathi- Gulabi babul • Telugu- Undrakampa Botanical name: Mimosa hamata Family: Mimosaceae (Touch-me-not) Synonyms: Mimosa armata Plant description The plant is branched and is thicket forming, height is around 1.5 meter. • Roots are brown in colour. • Stem is cylindrical in shape with brown branches, the branches posses pinkish stiff spines which are generally straight or curved near apex, young branches with longitudinal ribs and downy with dense growth of small hairs are present. • Leaves are alternate, stipulate, compound, bipinnate, 1.5 to 2.5 cm with rachis densely covered with hairs with 2-4 small curved spines on its abaxial surface. • Leaflets are present 5 to 9 pairs, ovate, oblong, tip acute or mucronate, glabrous on the adaxial surface but densely pubescent beneath, rounded but oblique at base.
  • 2. Parvej et al. Mimosa Hamata Willd. : A Review On Ethnobotanical, Phytochemical And Pharmacological Profile 11 © 2010, IJPBA. All Rights Reserved. • Inflorescence: globose head born in the axil of leaves, mostly crowded near the distal ends of young branches. • Flowers are sessile pinkish, tetramerous, actinomorphic. • Calyx are 2 mm long, divided nearly half way down. • Corolla are lobed, ovate-oblong and acute. • Stamens are pink, anther-lobed, creamy yellow, bithecous, basifixed. • Gynoecium: monocarpellary, unilocular, marginal placentation, superior, present on a stalk, elongated, curved and pubescent. • Stigmas are inconspicuous. • Fruits are legume, falcate or spirally coiled, one seeded. • Seeds are oval, green when young turning to chestnut brown on maturation. • Flowering: July-October; • Fruiting: August-November. Phytoconstituents All the plant parts (stem, leaves, flowers and roots) of Mimosa hamata were investigated for the chemical constituents. Therapeutically important compounds isolated from M. hamata include 4- ethylgallic acid from fresh flowers. [2] , triterpene saponin B (3-O-Larabinosyl-D-glucosyl morolic acid), mimonoside A, B, C and saponin A (3-O-D- glucosyl-L-rhamnosyl morolic acid) from the roots [3], [4], [7] , ethylgallate and gallic acid from leaves [3] Pharmacological activity Antimicrobial activity M. hamata willd. posses antimicrobial activity, crude ethanolic extract of aerial part of Mimosa hamata and deproteinized leaf extract showed their inhibitory effect against microorganisms such as bacteria and fungi. [5] Antiviral activity Ethanolic extract of aerial part of Mimosa hamata posses antiviral activities against Herpes simplex, Poliomylietes and Stomatitis. Petroleum ether and chloroform extracts also exhibited potential effect against V. Stomatitis and Herpes simplex. Studies revealed that the bio efficacy of the extracts of whole plant were more effective than the fractions obtained from callus tissues. Methanolic extract of roots were also reported for their antiviral activities against Measles, Semliki forest, Herpes simplex and Vesicular stomatitis.[3], [5], [6] Antioxidant activity Methanolic extracts of this plant was studied for higher antioxidant activity and result was positive with 6.5 μg ml-1 RC value and Comparison to the dichloromethane extracts also revealed that extract of leaves, stem, root and seeds of M. hamata have antioxidant potential. [7, 8, 9] Aphrodisiac activity Mimosa hamata is also used as herbal aphrodisiac for providing ameliorating effect on sexual dysfunction but it has not been clinically evaluated for its aphrodisiac activities. Many herbal aphrodisiac plants have large gap between traditional knowledge and pharmacological evidence. Tradition Claims The plant is widely used as an anti asthmatic; wound healing, analgesic, anti-inflammatory, contraceptive, anti-microbial, anti-viral, anti fungal, antioxidant, blood-purifier, anti-diarrheal and contraceptive agent. Kanjar tribe in Rajasthan use this plant for treatment of bronchitis and diarrhea in children. In Maharashtra its leaves are used for offering prayers to god for the good health of new born. The plant is also used as ornament among various tribes in Maharashtra. DISCUSSION Mimosa hamata is found in arid regions of india and is easily seen in regions like thar desert. This plant is used as fodder for goats and camels. The plant is widely use as a traditional medicine in various tribes from north to south in India. The plant has its traditional use as anti-asthmatic, wound-healing, analgesic, anti-inflammatory, contraceptive, anti-microbial, anti-viral, anti fungal, antioxidant, anti-diarrheal, blood-purifier and contraceptive agent and is used by different tribes and societies in India but very little scientific research has been done on this plant till now. Therefore there is need of scientific research on M. hamata to evaluate traditional medicinal use of this plant. REFERENCE 1. Singh Renu, Jasrai Yogesh T (2010 Mimosa hamta willd, A plant with anti pathogenic property, International Journal of aromatic medicinal plants vol.no.2 no. 4 page no. 677-682(2249-4340). 2. Mehta, B.K., Sharma, S., Dubey, A. 1988. 4- ethylgallic acid from two Mimosa IJPBA, Jan-Feb, 2016, Vol. 8, Issue, 1
  • 3. Parvej et al. Mimosa Hamata Willd. : A Review On Ethnobotanical, Phytochemical And Pharmacological Profile 12 © 2010, IJPBA. All Rights Reserved. species, Phytochemistry, 27(9): 3004- 3005. 3. Jain, R., Arora, R. 1997. 3-O-L- Arabinosyl-Dglucosyl morolic acid from Mimosa hamata. Journal of Medicinal and Aromatic Plant Sciences, 19: 22-23. 4. Jain, R., Arora, R., Jain, S.C. 1997b. Saponins from the roots of Mimosa hamata Willd. Indian Journal of Chemistry, 36B: 61-64. 5. Mukadam, D.S., Balkhande, L.D., Umalkar, G.V. 1976. Antifungal activities indeproteinized leaf extracts of weeds and non-weeds. Indian Journal of Microbiology, 16: 78. 6. Jain, S.C., Jain, R., Vlietinck, A.J. 2004. In vivo and in vitro antimicrobial efficacy of Mimosa hamata. Indian Journal of Biotechnology,3: 271-273. 7. Jain, R., Arora, R., Alam, S., Jain, S.C. 1997a. Pharmacological evaluation of Mimosa hamata roots. Fitoterapia, 68(4): 377-388. 8. Singh, S.C., Jain, R. 2009. Antioxidant activity of some medicinally important arid zone plants. Asian Journal of Experimental Sciences, 23(1): 215-221. 9. Jain, S.C., Jain, R., Singh, R. 2009b. Antioxidant activity of mimonosides isolated from in vitro regenerated plants of Mimosa hamata Willd. Indian Journal of Plant Physiology, 14(2): 124-129. 10. Singh, R., Jain, S.C. 2009. Antioxidant activity of some medicinally important arid zone plants. Asian Journal of Experimental Sciences, 23(1): 215-221. 11. Jain Renuka, Jain S.C. Studies (2014) on Antimicrobial and Antioxidant Potentials of Triterpenoidal Saponins from Mimosa hamata Willd. International Journal of Pharmaceutical and Phytopharmacological Research (eIJPPR) SSN (Online) 2249- 6084 (Print) 2250-1029. 12. Ali, M.S., Azhar, I., Ahmad, F., Ahmad V.U., Usman ghani R.U. 2001. Antimicrobial screening of Mimoaceous plants. Pharmaceutical Biology, 39(1): 43- 46. IJPBA, Jan-Feb, 2016, Vol. 8, Issue, 1