1. Pulmonary Aerosol
SUBJECT NAME – NOVEL DRUG DELIVERY SYSTEM
SUBJECT CODE - PT716B
Rima samanta
Roll – 19301920034
Reg no – 201930201910072
4th year, 7th semester
Bengal school of technology
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2. What is Pulmonary Aerosol?
Pulmonary aerosol refers to the
inhalation of small particles or
droplets into the lungs. These
particles can be solid or liquid and
are typically suspended in air.
Pulmonary aerosol plays a crucial
role in the delivery of medications
and treatment of respiratory
diseases.
Photo by cottonbro studio
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3. Sources of Pulmonary Aerosols
Pulmonary aerosols can come
from a variety of sources, both
natural and man-made.
Natural sources include dust,
pollen, and smoke from wildfires.
Man-made sources include
industrial emissions, vehicle
exhaust, and aerosol sprays.
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4. Importance of Pulmonary Aerosol
Pulmonary aerosol offers several
advantages in the field of medicine.
It allows targeted drug delivery
directly to the lungs, minimizing
systemic side effects. It is also a
non-invasive method for
administering medications,
providing convenience to patients.
Additionally, it enables rapid
absorption of drugs into the
bloodstream due to the large
surface area of the lungs.
Photo by ALINA MATVEYCHEVA
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5. Devices for Pulmonary Aerosol
Delivery
Various devices are used for
delivering aerosol to the lungs.
These include metered dose inhalers
(MDIs), dry powder inhalers (DPIs),
nebulizers, and vibrating mesh
nebulizers. Each device has its own
mechanism of generating and
delivering aerosol particles.
Photo by Karolina Grabowska
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6. Treating Pulmonary Aerosols
The treatment of pulmonary
aerosols depends on the type and
severity of the effects.
Common treatments include
bronchodilators to open the
airways, corticosteroids to reduce
inflammation, and antibiotics to
treat infections.
It is important to seek medical
attention if symptoms persist or
worsen.
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7. Types of Pulmonary Aerosol
Medications
There are different types of medications that can be delivered
via pulmonary aerosol. These include bronchodilators,
corticosteroids, antibiotics, antivirals, and mucolytics. Each
medication targets specific respiratory conditions and helps in
managing symptoms or treating underlying diseases.
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8. Factors Affecting Pulmonary
Aerosol Deposition
Several factors influence the
deposition of aerosol particles in the
lungs. These include particle size,
inhalation technique, breath-hold
duration, lung diseases, and patient
variability. Understanding these
factors is essential for optimizing
aerosol therapy and ensuring
effective drug delivery.
Photo by Michael Burrows
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9. Challenges in Pulmonary Aerosol
Delivery
Despite its benefits, pulmonary
aerosol delivery faces certain
challenges. One of the major
challenges is the coordination
required between the patient's
inhalation and device actuation.
Inadequate inhalation technique,
device misuse, and poor patient
adherence also pose challenges to
achieving optimal drug delivery.
Photo by Cas Holmes
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10. Applications of Pulmonary Aerosol
Therapy
Pulmonary aerosol therapy is used
for various applications. It is
commonly employed in the
treatment of asthma, chronic
obstructive pulmonary disease
(COPD), cystic fibrosis, and
respiratory infections. It can also be
used for diagnostic purposes such as
lung function testing.
Photo by Luci
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11. Advancements in Pulmonary
Aerosol Technology
Advancements in technology have
led to the development of novel
pulmonary aerosol delivery systems.
These include smart inhalers with
integrated sensors to monitor
medication usage, portable
nebulizers for on-the-go treatment,
and particle engineering techniques
for optimizing drug delivery
efficiency.
Photo by Karolina Grabowska
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12. Safety Considerations in
Pulmonary Aerosol Therapy
Safety is a crucial aspect of
pulmonary aerosol therapy. It is
important to ensure proper cleaning
and maintenance of devices to
prevent contamination. Patient
education regarding correct device
usage and adherence to prescribed
medication dosage is also essential.
Additionally, healthcare
professionals must monitor for any
adverse effects or drug interactions.
Photo by Anamul Rezwan
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13. Future Directions of Pulmonary
Aerosol Research
Ongoing research in the field of
pulmonary aerosol aims to improve
drug delivery efficiency and
enhance treatment outcomes. Areas
of focus include the development of
more precise and personalized
inhalation therapies, exploring
nanotechnology for targeted drug
delivery, and investigating the use of
gene therapy in respiratory diseases.
Photo by ALINA MATVEYCHEVA
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14. Conclusion
Pulmonary aerosol plays a vital role
in the treatment of respiratory
diseases. It enables targeted drug
delivery, offers convenience to
patients, and allows for rapid
absorption of medications. However,
challenges such as coordination and
patient adherence need to be
addressed for optimal outcomes.
Ongoing advancements and research
in this field hold promise for further
improving pulmonary aerosol
therapy.
Photo by CDC
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References
2. Tekade, Rakesh K., ed. (30 November 2018). Basic fundamentals of drug
delivery
1. Tiwari, Gaurav; Tiwari, Ruchi; Sriwastawa, Birendra; Bhati, L;
Pandey, S; Pandey, P; Bannerjee, Saurabh K (2012). "Drug delivery
systems: An updated review
