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Clinical considerations of adverse drug effects

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This document summarizes various types of adverse drug effects including pharmacological toxicity, idiosyncratic reactions, drug allergies, hepatotoxicity, nephrotoxicity, drug interactions, photosensitization, and local pain and tissue injuries. It discusses the mechanisms, clinical signs, and management of these adverse effects for different drug classes in veterinary medicine. Risk factors, treatment approaches, and ways to minimize adverse reactions are also covered.

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CLINICAL CONSIDEARTIONS IN ADVERSE EFFECTS OF DRUGS
An adverse drug effect ,[object Object],[object Object],[object Object],[object Object]
An adverse drug reaction (ADR) ,[object Object],[object Object],[object Object],[object Object]
Types of adverse drug reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IDIOSYNCRACY ,[object Object],[object Object],[object Object]
IDIOSYNCRACY …. contd ,[object Object],[object Object],[object Object],[object Object]
DRUG ALLERGY/ HYPERSENSITIVITY ,[object Object],[object Object],[object Object]
DRUG ALLERGY/ HYPERSENSITIVITY… contd ,[object Object],[object Object],[object Object]
Clinical manifestations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HEPATOTOXICITY ,[object Object],[object Object],[object Object]
HEPATOTOXICITY… contd ,[object Object],[object Object],[object Object],[object Object],[object Object]
NEPHROTOXICITY ,[object Object],[object Object]
NEPHROTOXICITY….contd ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
INCOMPATIBILITY ,[object Object],[object Object],[object Object],[object Object],[object Object]
TERATOGENICITY ,[object Object],[object Object],[object Object],[object Object]
TERATOGENICITY…contd ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TERATOGENICITY…contd ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TERATOGENICITY…contd ,[object Object],[object Object],[object Object],[object Object],[object Object]
CARCINOGENICITY AND MUTAGENICITY ,[object Object],[object Object],[object Object]
CNS DISTURBANCES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
GASTROINTESTINAL DISTURBANCES ,[object Object],[object Object]
DRUG INTERACTIONS ,[object Object],[object Object]
DRUG INTERACTIONS….contd ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DRUG INTERACTIONS….contd ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DRUG INTERACTIONS….contd ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PHOTOSENSITIZATION ,[object Object],[object Object],[object Object]
PHOTOSENSITIZATION…contd ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PHOTOSENSITIZATION..contd ,[object Object],[object Object],[object Object],[object Object]
PHOTOSENSITIZATION..contd ,[object Object],[object Object],[object Object],[object Object],[object Object]
LOCAL PAIN, TISSUE INJURY AND IRRITATION ,[object Object],[object Object],[object Object],[object Object],[object Object]
LOCAL PAIN, TISSUE INJURY AND IRRITATION….contd ,[object Object],[object Object],[object Object],[object Object]
LOCAL PAIN, TISSUE INJURY AND IRRITATION….contd ,[object Object],[object Object],[object Object],[object Object],[object Object]
LOCAL PAIN, TISSUE INJURY AND IRRITATION….contd ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LOCAL PAIN, TISSUE INJURY AND IRRITATION….contd ,[object Object],[object Object],[object Object],[object Object]
LOCAL PAIN, TISSUE INJURY AND IRRITATION….contd ,[object Object],[object Object],[object Object],[object Object],[object Object]
Guidelines for avoiding injection site complications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]

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Clinical considerations of adverse drug effects

  • 1. CLINICAL CONSIDEARTIONS IN ADVERSE EFFECTS OF DRUGS
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