Creative Biogene has been perfecting plasmid DNA production for many years. We offer a wide range of plasmid preparation services for many applications, including research, preclinical, clinical, and diagnostic applications. The plasmid DNA isolation service will be suitable for transfection and animal studies to both biotechnology researchers and pharmaceutical companies. Our goal is to provide you with the most affordable, high-quality plasmid DNA manufacturing services that ensure your satisfaction in a timely and professional manner.

1. Plasmid DNA—An Indispensable
Tool for Molecular Biology
by Creative Biogene

2. Definition
• A plasmid is a small DNA molecule within
a cell that is physically separated from
a chromosomal DNA and can replicate
independently.
• Mostly found in bacteria (presents to be as
a small, circular, double-stranded DNA
molecule—as the picture shows), also
found in archaea and eukaryotic
organisms.

3. Natural and Artificial Plasmids
In nature, plasmids often carry genes that is essential for the survival of
an organism. Therefore people generate artificial plasmids that are
widely used as vectors to drive the replication of recombinant
DNA sequences within host organisms. They can be used for:
• Cloning
• Protein production
• Gene therapy
• Disease models
Or we could say that plasmids serve as cell transfection, support DNA
vaccine development, antibody production, and other preclinical and
clinical research projects.

4. Advantages
In addition to reasons above, factors that make plasmids
either more useful or easier to work with include:
1. They are small. If they are small, they are easier to
isolate (you get more), handle (less shearing), and
transform.
2. They have multiple restriction enzyme sites. More
sites give you greater flexibility in cloning, perhaps even
allowing for directional cloning.
• 3. They have multiple ORIs. It is important to note that
two genes must have different ORIs if they are going to
be inserted in the same plasmid.

5. Plasmid DNA Purification
• Plasmid DNA purification is an very
important technique for various molecular
biology and biochemistry labs. They can
be used for a variety of applications such
as, research, transfection, preclinical,
bacterial transformation, clinical, restriction
endonuclease digestion, diagnostic, PCR,
sequencing, and in vitro transcription, etc.

6. Commercial Supplier—Creative Biogene
• Creative Biogene has been perfecting plasmid DNA
production for many years. We offer a wide range of
plasmid preparation services for many applications,
including research, preclinical, clinical, and diagnostic
applications. The plasmid DNA isolation service will be
suitable for transfection and animal studies to both
biotechnology researchers and pharmaceutical
companies. Our goal is to provide you with the most
affordable, high-quality plasmid DNA manufacturing
services that ensure your satisfaction in a timely and
professional manner.

7. Features of Creative Biogene’s
Plasmid DNA Production Service:
• Construct your plasmid according to your
requirements.
• Produce plasmids for applications both in
vitro and in vivo.
• Robust manufacturing protocols.
• Flexible scale: up to gram level.
• High standard quality control.
• Short turn-around time.

8. Other services provided by
Creative Biogene:
• Custom Viral Service
• RNAi Service
• Gene Service
• Aptamer Service
• Plasmid DNA Production Service
• Stable Cell Line Generation
• Oligonucleotide Synthesis Service

9. Contact
• USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Email ： info@creative-biogene.com
• United Kingdom
St John's Innovation Centre, Cowley Road, Cambridge CB4 0WS,
UK
Tel: 44-207-048-3343
Email ： info@creative-biogene.com
• Web: http://www.creative-biogene.com/Services/Plasmid-DNA-
Production-Service.html

10. Contact
• USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Email ： info@creative-biogene.com
• United Kingdom
St John's Innovation Centre, Cowley Road, Cambridge CB4 0WS,
UK
Tel: 44-207-048-3343
Email ： info@creative-biogene.com
• Web: http://www.creative-biogene.com/Services/Plasmid-DNA-
Production-Service.html