2. The Liver
• Largest gland in the body (1.5 Kg)
• Under the diaphragm, within the rib
cage in the upper right quadrant of the
abdomen
3. The Liver
•4 Lobes
Major: left and
right
Minor: caudate and
quadrate
•Ducts
Common hepatic
Cystic
From gallbladder
Common bile -
Choledochus
Joins pancreatic duct at
hepatopancreatic ampulla
4. liver
•Liver lobules – hexagonal structures consisting of
hepatocytes
• Hepatocytes radiate outward from a central vein
•Hepatocytes produce bile
Bile flows through canals called bile canaliculi to a bile
duct
Bile ducts leave the liver via the common hepatic duct
• At each of the six corners of a lobule is a portal
triad
• Liver sinusoids
9. Functions of Liver
• Metabolic
Synthesis
Breakdown
Other functions – storage of vitamin
A,D,B12,F…
• Excretion of waste products from bloodstream
into bile
• Vascular – storage of blood