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BY Muhammad Ramzan Ul Rehman Nishtar Ken 1
BY Muhammad Ramzan Ul Rehman Nishtar Ken 
2
—“DEPTH 
PERCEPTION”  The ability to determine 
distance is called depth 
perception. 
 A person normally perceives 
distance by three major 
means: 
 (1) the sizes of the images of 
known objects on the retina 
 (2) the phenomenon of moving 
parallax, 
 (3) the phenomenon of 
stereopsis, binocular Vision. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 3
 by using this mechanism of moving parallax, one can tell the relative distances of 
different objects even though only one eye is used. 
 It is almost entirely this moving or binocular parallax (or stereopsis) that gives a 
person with two eyes far greater ability to judge relative distances when objects 
are nearby than a person who has only one eye. 
 However, stereopsisis virtually useless for depth perception at distances beyond 
50 to 200 feet. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 4
 An instrument to examine the inside 
of eye, especially the retina and optic 
disc 
 It has a light source on the end. 
 Eye can be magnified. 
 We can look directly through the 
pupil to the back of eye. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 5
BY Muhammad Ramzan Ul Rehman Nishtar Ken 6
BY Muhammad Ramzan Ul Rehman Nishtar Ken 7
BY Muhammad Ramzan Ul Rehman Nishtar Ken 8
BY Muhammad Ramzan Ul Rehman Nishtar Ken 9
 Ability of the eye to determine 
the precise shape and details 
of the object is called visual 
acuity 
 For humans, it is 30 seconds of 
an arc. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 10
BY Muhammad Ramzan Ul Rehman Nishtar Ken 11
 Chart for testing eyes consists of 
letters of different sizes placed 20 
feet ( 6 meters) away from the person 
being tested. 
 Person is said to have normal vision 
if he can see the letters from the 
distance of 20 feet or 6 meters. so he 
have vision of 20/20 or 6/6 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 12
 PHOTOCHEMICALS in cones have almost the same 
composition as Rhodopsin in Rods. 
 Protein portion (opsins) in cones are called Photopsins. 
 The color sensitive pigments of the cones, are the 
combinations of retinal and photopsins. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 13
Cones are selectively sensitive to different 
colours: 
Blue 
Green 
Red 
Only one of three types of color pigments is 
present in each of the different cones 
These color pigments are respectively called: 
Blue-sensitive pigment 
Green sensitive pigment 
Red-sensitive pigment 
YOUNG-HELMHOLTZ THEORY(theory of trichromatic color 
vision) 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 14
 BLUE SENSITIVE PIGMENTS 
Peak absorbance of light 
wavelength 445nm 
 GREEN SENSITIVE PIGMENTS 
Peak absorbance of light 
wavelength 535nm 
 RED SENSITIVE PIGMENTS 
Peak absorbance of light 
wavelength 570nm 
 RHODOPSIN 
Peak absorbance of light 
wavelength 505nm 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 15
BY Muhammad Ramzan Ul Rehman Nishtar Ken 16
 Human eye can detect all gradations of colors. 
 Red, green & blue monochromatic light mixed in different combinations. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 17
Orange monochromatic light 
stimulates: 
 Red cones-------99%. 
 Green cones -----42%. 
 Blue cones---------0%. 
 Ratio of stimulation -------99:42:0. 
 CNS interprets this ratio as 
sensation of orange color. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 18
Blue monochromatic light stimulates 
 Red cones-------0%. 
 Green cones -----0%. 
 Blue cones---------97%. 
 Ratio of stimulation -------0:0:97 
 CNS interprets this ratio as 
sensation of blue color. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 19
 Ratio of 83:83:0-------------yellow. 
 Ratio of 31:67:36-----------green. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 20
• When there is Equal stimulation of all cones there is perception of white light. 
• White is combination of all the wavelengths of the spectrum. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 21
 The term Colour blindness is misleading if taken literally, because colourblind 
people CAN see colors, but cannot make out the difference between some 
complementary colors. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 22
 CAUSE: Due to congenital absence of a single group of color receptive cones from 
the eyes 
 Person is unable to distinguish some colors from others. 
 Usually…..absence of either L (Red) cones or M (Green) cones. 
 People with two functional cones are called Dichromate. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 23
 Person is unable to distinguish red from green due to missing of either of these 
cones. 
 Absence of M (Green)cones :Deuteranopia 
 Absence of L (Red) cones:Protanopia 
 Green, orange, red & yellow colors have wavelength 525 to 675nm. 
 These colors are normally distinguished from one another by red & green cones. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 24
 Genetic disorder only in males 
 Photopsins are coded on X chromosomes. 
 It never occurs in females ,because one of the two X Chromosomes has normal 
gene for each type of Cone. 
 about 8% of women are color blindness carriers 
 Females are only color blindness carrier. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 25
 Rarely blue cones are missing. 
 Genetically inherited state. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 26
Rapid method to determine color blindness. 
 Charts are arranged with a confusion of spots of several 
different colors. 
These charts observe spectral sensitivity curves of the 
different cones at same time. 
 Ideally a collection of 38 plates filled with colored dots 
build the base of this test. The dots are colored in different 
shades and a number is hidden inside with shades of 
another color. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 27
 Ishihara Charts were made by a 
Japanese ophthalmologist Shinobu 
Ishihara (1879-1963). 
 He was working at the Military 
Medical School 
 He was asked to devise a test to 
screen military recruits for 
abnormalities of colour vision. 
 His assistant was a colourblind 
physician who helped him test the 
plates. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 28
The person 
with normal 
color vision 
reads 74, 
where as the 
red green 
blind person 
reads 21. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 29
 Person with 
normal 
vision reads 
42, red 
blind 
person 
reads2,and 
green blind 
person 
reads 4. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 30
Eye Movements are Controlled by 
Neural Pathways for Control of Eye 
Movementairs of Muscles. 
Superior and inferior 
obliques rotate the 
eyes 
Medial and lateral 
recti move eyes side 
to side 
Superior and inferior 
recti move eyes up 
and down 
BY Muhammad Ramzan Ul Rehman Nishtar Ken Figure 51-7; Guyton & Hall 31
 Fixation Movement: 
Movement of eyes to bring a 
discrete portion of visual field into 
focus on the fovea. 
Controlled by 
Frontal eye fields 
Brodmann’s area 8 and 19 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 32
 Fixation movements of the eyes controlled by 
two neuronal mechanisms, voluntary and 
involuntary. 
 Voluntary fixation movements controlled by an area in the 
premotor cortex. 
 Involuntary fixation mechanism causes eyes to “lock” on 
object of attention found with the voluntary fixation 
mechanism. Controlled by secondary visual areas of the 
occipital cortex. 
 Results from negative feedback mechanism controlled at the 
level of the superior colliculus that prevents objects of 
attention from leaving the foveal portion of the retina. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 33
Saccadic Movement 
Jumping of eyes from one object to another. 
each jump is called a Saccade and the 
movement is called Opticokinetic movements. 
Pursuit Movement 
Fixation of eyes to a moving object 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 34
When the visual scene is moving (turning the 
head), the eyes fix on one highlight after 
another in the visual field jumping at a rate of 2 
to 3 jumps/sec. These jumps are called saccades, 
and the movements are called opticokinetic 
movements. 
 Saccades occur very rapidly (only 10% of the 
time is spent making saccades). 
Vision is suppressed during a saccadic 
movement. 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 35
BY Muhammad Ramzan Ul Rehman Nishtar Ken 36
BY Muhammad Ramzan Ul Rehman Nishtar Ken 37
By Muhammad Ramzan UL Rehman 
BY Muhammad Ramzan Ul Rehman Nishtar Ken 
38

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Eye physiology from guyton and halls physiology Part 4

  • 1. BY Muhammad Ramzan Ul Rehman Nishtar Ken 1
  • 2. BY Muhammad Ramzan Ul Rehman Nishtar Ken 2
  • 3. —“DEPTH PERCEPTION”  The ability to determine distance is called depth perception.  A person normally perceives distance by three major means:  (1) the sizes of the images of known objects on the retina  (2) the phenomenon of moving parallax,  (3) the phenomenon of stereopsis, binocular Vision. BY Muhammad Ramzan Ul Rehman Nishtar Ken 3
  • 4.  by using this mechanism of moving parallax, one can tell the relative distances of different objects even though only one eye is used.  It is almost entirely this moving or binocular parallax (or stereopsis) that gives a person with two eyes far greater ability to judge relative distances when objects are nearby than a person who has only one eye.  However, stereopsisis virtually useless for depth perception at distances beyond 50 to 200 feet. BY Muhammad Ramzan Ul Rehman Nishtar Ken 4
  • 5.  An instrument to examine the inside of eye, especially the retina and optic disc  It has a light source on the end.  Eye can be magnified.  We can look directly through the pupil to the back of eye. BY Muhammad Ramzan Ul Rehman Nishtar Ken 5
  • 6. BY Muhammad Ramzan Ul Rehman Nishtar Ken 6
  • 7. BY Muhammad Ramzan Ul Rehman Nishtar Ken 7
  • 8. BY Muhammad Ramzan Ul Rehman Nishtar Ken 8
  • 9. BY Muhammad Ramzan Ul Rehman Nishtar Ken 9
  • 10.  Ability of the eye to determine the precise shape and details of the object is called visual acuity  For humans, it is 30 seconds of an arc. BY Muhammad Ramzan Ul Rehman Nishtar Ken 10
  • 11. BY Muhammad Ramzan Ul Rehman Nishtar Ken 11
  • 12.  Chart for testing eyes consists of letters of different sizes placed 20 feet ( 6 meters) away from the person being tested.  Person is said to have normal vision if he can see the letters from the distance of 20 feet or 6 meters. so he have vision of 20/20 or 6/6 BY Muhammad Ramzan Ul Rehman Nishtar Ken 12
  • 13.  PHOTOCHEMICALS in cones have almost the same composition as Rhodopsin in Rods.  Protein portion (opsins) in cones are called Photopsins.  The color sensitive pigments of the cones, are the combinations of retinal and photopsins. BY Muhammad Ramzan Ul Rehman Nishtar Ken 13
  • 14. Cones are selectively sensitive to different colours: Blue Green Red Only one of three types of color pigments is present in each of the different cones These color pigments are respectively called: Blue-sensitive pigment Green sensitive pigment Red-sensitive pigment YOUNG-HELMHOLTZ THEORY(theory of trichromatic color vision) BY Muhammad Ramzan Ul Rehman Nishtar Ken 14
  • 15.  BLUE SENSITIVE PIGMENTS Peak absorbance of light wavelength 445nm  GREEN SENSITIVE PIGMENTS Peak absorbance of light wavelength 535nm  RED SENSITIVE PIGMENTS Peak absorbance of light wavelength 570nm  RHODOPSIN Peak absorbance of light wavelength 505nm BY Muhammad Ramzan Ul Rehman Nishtar Ken 15
  • 16. BY Muhammad Ramzan Ul Rehman Nishtar Ken 16
  • 17.  Human eye can detect all gradations of colors.  Red, green & blue monochromatic light mixed in different combinations. BY Muhammad Ramzan Ul Rehman Nishtar Ken 17
  • 18. Orange monochromatic light stimulates:  Red cones-------99%.  Green cones -----42%.  Blue cones---------0%.  Ratio of stimulation -------99:42:0.  CNS interprets this ratio as sensation of orange color. BY Muhammad Ramzan Ul Rehman Nishtar Ken 18
  • 19. Blue monochromatic light stimulates  Red cones-------0%.  Green cones -----0%.  Blue cones---------97%.  Ratio of stimulation -------0:0:97  CNS interprets this ratio as sensation of blue color. BY Muhammad Ramzan Ul Rehman Nishtar Ken 19
  • 20.  Ratio of 83:83:0-------------yellow.  Ratio of 31:67:36-----------green. BY Muhammad Ramzan Ul Rehman Nishtar Ken 20
  • 21. • When there is Equal stimulation of all cones there is perception of white light. • White is combination of all the wavelengths of the spectrum. BY Muhammad Ramzan Ul Rehman Nishtar Ken 21
  • 22.  The term Colour blindness is misleading if taken literally, because colourblind people CAN see colors, but cannot make out the difference between some complementary colors. BY Muhammad Ramzan Ul Rehman Nishtar Ken 22
  • 23.  CAUSE: Due to congenital absence of a single group of color receptive cones from the eyes  Person is unable to distinguish some colors from others.  Usually…..absence of either L (Red) cones or M (Green) cones.  People with two functional cones are called Dichromate. BY Muhammad Ramzan Ul Rehman Nishtar Ken 23
  • 24.  Person is unable to distinguish red from green due to missing of either of these cones.  Absence of M (Green)cones :Deuteranopia  Absence of L (Red) cones:Protanopia  Green, orange, red & yellow colors have wavelength 525 to 675nm.  These colors are normally distinguished from one another by red & green cones. BY Muhammad Ramzan Ul Rehman Nishtar Ken 24
  • 25.  Genetic disorder only in males  Photopsins are coded on X chromosomes.  It never occurs in females ,because one of the two X Chromosomes has normal gene for each type of Cone.  about 8% of women are color blindness carriers  Females are only color blindness carrier. BY Muhammad Ramzan Ul Rehman Nishtar Ken 25
  • 26.  Rarely blue cones are missing.  Genetically inherited state. BY Muhammad Ramzan Ul Rehman Nishtar Ken 26
  • 27. Rapid method to determine color blindness.  Charts are arranged with a confusion of spots of several different colors. These charts observe spectral sensitivity curves of the different cones at same time.  Ideally a collection of 38 plates filled with colored dots build the base of this test. The dots are colored in different shades and a number is hidden inside with shades of another color. BY Muhammad Ramzan Ul Rehman Nishtar Ken 27
  • 28.  Ishihara Charts were made by a Japanese ophthalmologist Shinobu Ishihara (1879-1963).  He was working at the Military Medical School  He was asked to devise a test to screen military recruits for abnormalities of colour vision.  His assistant was a colourblind physician who helped him test the plates. BY Muhammad Ramzan Ul Rehman Nishtar Ken 28
  • 29. The person with normal color vision reads 74, where as the red green blind person reads 21. BY Muhammad Ramzan Ul Rehman Nishtar Ken 29
  • 30.  Person with normal vision reads 42, red blind person reads2,and green blind person reads 4. BY Muhammad Ramzan Ul Rehman Nishtar Ken 30
  • 31. Eye Movements are Controlled by Neural Pathways for Control of Eye Movementairs of Muscles. Superior and inferior obliques rotate the eyes Medial and lateral recti move eyes side to side Superior and inferior recti move eyes up and down BY Muhammad Ramzan Ul Rehman Nishtar Ken Figure 51-7; Guyton & Hall 31
  • 32.  Fixation Movement: Movement of eyes to bring a discrete portion of visual field into focus on the fovea. Controlled by Frontal eye fields Brodmann’s area 8 and 19 BY Muhammad Ramzan Ul Rehman Nishtar Ken 32
  • 33.  Fixation movements of the eyes controlled by two neuronal mechanisms, voluntary and involuntary.  Voluntary fixation movements controlled by an area in the premotor cortex.  Involuntary fixation mechanism causes eyes to “lock” on object of attention found with the voluntary fixation mechanism. Controlled by secondary visual areas of the occipital cortex.  Results from negative feedback mechanism controlled at the level of the superior colliculus that prevents objects of attention from leaving the foveal portion of the retina. BY Muhammad Ramzan Ul Rehman Nishtar Ken 33
  • 34. Saccadic Movement Jumping of eyes from one object to another. each jump is called a Saccade and the movement is called Opticokinetic movements. Pursuit Movement Fixation of eyes to a moving object BY Muhammad Ramzan Ul Rehman Nishtar Ken 34
  • 35. When the visual scene is moving (turning the head), the eyes fix on one highlight after another in the visual field jumping at a rate of 2 to 3 jumps/sec. These jumps are called saccades, and the movements are called opticokinetic movements.  Saccades occur very rapidly (only 10% of the time is spent making saccades). Vision is suppressed during a saccadic movement. BY Muhammad Ramzan Ul Rehman Nishtar Ken 35
  • 36. BY Muhammad Ramzan Ul Rehman Nishtar Ken 36
  • 37. BY Muhammad Ramzan Ul Rehman Nishtar Ken 37
  • 38. By Muhammad Ramzan UL Rehman BY Muhammad Ramzan Ul Rehman Nishtar Ken 38