This document provides guidance for promoting responsible agricultural supply chains. It discusses why businesses should adopt responsible business conduct practices to obtain and retain their social license to operate, reduce risks, protect and create value, and facilitate participation in global value chains. It also outlines several existing standards for responsible business conduct related to issues like human rights, labor rights, land tenure rights, and environmental sustainability. The guidance advocates for a risk-based due diligence approach and provides an example of risk mitigation measures related to land tenure rights. It proposes applying this framework to all enterprises along agricultural supply chains.