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LITERATURE REVIEWS
PRESENTED BY:
Clara Fowler, Manager of Research
Services & Assessment
Literature reviews are a summary and critical evaluation
of particular topic within a specific discipline.
They are often connected with a case report or case
series.
They can point out where literature is lacking or
further research is needed.
Image by Mark Smicklas,
https://www.flickr.com/photos/intersectionconsulting/albums/72157614274686504
Literature reviews are part of an ongoing scholarly
conversation. No one piece of scholarly work usually
represents the only perspective.
Image by Mark Smicklas,
https://www.flickr.com/photos/intersectionconsulting/albums/72157614274686504
Developing a literature reviews comes with the
responsibility to seek out accurate and reliable
information.
It is important to assess the information you find and
understand its context.
Image by Mark Smicklas,
https://www.flickr.com/photos/intersectionconsulting/albums/72157614274686504
A well-research literature review aims to:
• relevant sources that are highly-cited in the literature
• relevant sources from other disciplines
• authors that are experts in the field
Photo by Matthias Werner
https://www.flickr.com/photos/matthiaswerner1984/5723015665/
Databases to start your search:
• UpToDate
• PubMed
• Scopus
• TRIP (Turning Research Into Practice)
Photo by Robin Byles
https://www.flickr.com/photos/robinbyles/3158141956/
Use the PICO format for clinical
questions
In patients with Dry Eye Disease, does
the new drug Xiidra improve quality of
life over OTC eye drops?
Patient/Population: Dry Eye Disease
Intervention: Xiidra
Comparison: OTC eye drops
Outcome: Quality of life
PICO QUESTIONS
Search strategies
1. Keyword searching
2. Subject heading searching
3. (MeSH, EMTREE, CINAHL Headings)
4. Reference lists
5. Cited references
Photo by Hasin Hayder
https://www.flickr.com/photos/storyteller/6436685931/
Search strategies: Keywords
• Create a list of commonly used terms to
describe each of your concepts
• As you find relevant articles, see if there
are keywords to add to the search
• Combine synonyms using OR
• Combine different concepts using AND
Photo by Paul Wilkinson
https://www.flickr.com/photos/eepaul/7008085799/
Constructing a Search
keywords & subject headings
Drug names:
Brand: Xiidra
Scientific: Lifitegrast
Experimental: SAR 1118
Class: lymphocyte function-associated
antigen 1 (LFA-1) antagonist
Condition names:
Dry Eye Disease
Dry Eye Syndromes (MeSH)
Comparison names:
Nonprescription drugs (MeSH), Over the
counter, OTC, non-prescription
Lubricant Eye Drops (MeSH), artificial tear
drops, artificial tears, lubricating eye-drops
Photo by Wayne SH Lin
https://www.flickr.com/photos/wayne_lin/8319765817/
Boolean Operators:
Combining terms using AND and OR
(Xiidra OR Lifitegrast OR
SAR 1118) AND (dry eye
syndrome OR dry eye
disease)
Xiidra OR
Lifitegrast OR
SAR 1118
dry eye
syndrome OR
dry eye
disease
AND = different concepts
OR = synonyms for same concept
Organizing results
• Staying organized is key for a successful search
• Keep like items together
• Organize your search by concept or search technique
• Use a citation management system from the beginning (the Library
teaches classes in EndNote)
• Save or document your search strategies
Photo by Sarah Parrott
https://www.flickr.com/photos/thingsarebetterwithaparrott/2448698383/
Finishing a search
You are finished when you’ve:
• Searched multiple databases
• Identified the key authors/researchers
• Looked at the reference lists for on-target articles and found nothing new
Photo by Glamhag
https://www.flickr.com/photos/glamhag/1348879124/
QUESTIONS?
Call: 713-792-2282
Text: 281-369-4872
Twitter: @MDAndersonLib
Visit: Pickens Floor 21
Email: rml-help@mdanderson.org
Photo by Louis Vest
https://www.flickr.com/photos/oneeighteen/13960057990/

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Literature reviews: Finding the Evidence

  • 1. LITERATURE REVIEWS PRESENTED BY: Clara Fowler, Manager of Research Services & Assessment
  • 2. Literature reviews are a summary and critical evaluation of particular topic within a specific discipline. They are often connected with a case report or case series. They can point out where literature is lacking or further research is needed. Image by Mark Smicklas, https://www.flickr.com/photos/intersectionconsulting/albums/72157614274686504
  • 3. Literature reviews are part of an ongoing scholarly conversation. No one piece of scholarly work usually represents the only perspective. Image by Mark Smicklas, https://www.flickr.com/photos/intersectionconsulting/albums/72157614274686504
  • 4. Developing a literature reviews comes with the responsibility to seek out accurate and reliable information. It is important to assess the information you find and understand its context. Image by Mark Smicklas, https://www.flickr.com/photos/intersectionconsulting/albums/72157614274686504
  • 5. A well-research literature review aims to: • relevant sources that are highly-cited in the literature • relevant sources from other disciplines • authors that are experts in the field Photo by Matthias Werner https://www.flickr.com/photos/matthiaswerner1984/5723015665/
  • 6. Databases to start your search: • UpToDate • PubMed • Scopus • TRIP (Turning Research Into Practice) Photo by Robin Byles https://www.flickr.com/photos/robinbyles/3158141956/
  • 7. Use the PICO format for clinical questions In patients with Dry Eye Disease, does the new drug Xiidra improve quality of life over OTC eye drops? Patient/Population: Dry Eye Disease Intervention: Xiidra Comparison: OTC eye drops Outcome: Quality of life PICO QUESTIONS
  • 8. Search strategies 1. Keyword searching 2. Subject heading searching 3. (MeSH, EMTREE, CINAHL Headings) 4. Reference lists 5. Cited references Photo by Hasin Hayder https://www.flickr.com/photos/storyteller/6436685931/
  • 9. Search strategies: Keywords • Create a list of commonly used terms to describe each of your concepts • As you find relevant articles, see if there are keywords to add to the search • Combine synonyms using OR • Combine different concepts using AND Photo by Paul Wilkinson https://www.flickr.com/photos/eepaul/7008085799/
  • 10. Constructing a Search keywords & subject headings Drug names: Brand: Xiidra Scientific: Lifitegrast Experimental: SAR 1118 Class: lymphocyte function-associated antigen 1 (LFA-1) antagonist Condition names: Dry Eye Disease Dry Eye Syndromes (MeSH) Comparison names: Nonprescription drugs (MeSH), Over the counter, OTC, non-prescription Lubricant Eye Drops (MeSH), artificial tear drops, artificial tears, lubricating eye-drops Photo by Wayne SH Lin https://www.flickr.com/photos/wayne_lin/8319765817/
  • 11. Boolean Operators: Combining terms using AND and OR (Xiidra OR Lifitegrast OR SAR 1118) AND (dry eye syndrome OR dry eye disease) Xiidra OR Lifitegrast OR SAR 1118 dry eye syndrome OR dry eye disease AND = different concepts OR = synonyms for same concept
  • 12. Organizing results • Staying organized is key for a successful search • Keep like items together • Organize your search by concept or search technique • Use a citation management system from the beginning (the Library teaches classes in EndNote) • Save or document your search strategies Photo by Sarah Parrott https://www.flickr.com/photos/thingsarebetterwithaparrott/2448698383/
  • 13. Finishing a search You are finished when you’ve: • Searched multiple databases • Identified the key authors/researchers • Looked at the reference lists for on-target articles and found nothing new Photo by Glamhag https://www.flickr.com/photos/glamhag/1348879124/
  • 14. QUESTIONS? Call: 713-792-2282 Text: 281-369-4872 Twitter: @MDAndersonLib Visit: Pickens Floor 21 Email: rml-help@mdanderson.org Photo by Louis Vest https://www.flickr.com/photos/oneeighteen/13960057990/