2. Purpose Highlight retinal and choroidal circulation Detect early vascular pathologies Confirm diagnosis
3. How does it work? Charateristics applications Absorbs 465-490nm, emits 520-530nm Binding to plasma proteins, espAlbumin Selective visualization of its passage Confined to natural blood retinal barrier
4. The sequence: passage of dye after inj. Visualization 10 to 15 sec : Short posterior ciliary arteries. Choroidal flush, optic nerve head, cilioretinal artery. 11-18 sec: Retinal circulatiion, arteries-capillaries-veins. 20-25 sec: juxtrafoveal and perifoveal capillaries Maximal fluorescence around FAZ. The best time for PEAK PHASE IMAGING. 30 sec: First passage completed. Recirculation starts After 10min: total disappearance of dye.
5. The Interpretation Hypo-fluorescence Hyper-fluorescence Blocked: Media opacity, Hem Vascular Filling Defects: Occlusions, capillary non perfusion Autofluorescence Transmitted fluorescence Hyperfluorescence: 1. Abnormal Vessels: Angiomas, Tumours 2. Leakage: NV, Plebitis 3. Pooling: CSR, PED 4. Staining: Disc, drusen, chorioret. scar
