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MINISTRY OF HEALTH OF UKRAINE
LUGANSK STATE MEDICAL UNIVERSITY
DEPARTMENT OF PEDIATRICS
REPORT PRESENTED BY RUBEN
GOMBALANDI .
SUPERVISED BY ASST.PROF. OKSANA
BABINOVA.
ON
Lool at this cute being!!!!!
The next morning ,you find this!!!!!!!!!!!!!!!!!!
INTRODUCTION
Sudden infant death syndrome continues to be the most
common cause of post neonatal death, account for 25% of all
death between 1month of age and 1 year of Age.
SIDS Goes , by different names ‘’COT Death , Cribs.
Some environmental risk factors are modifiable
Reducing exposure to modifiable risk factors has lowered the
incidence of SIDS
New research indicates genetic risk factors
Actual risk of SIDS may depend on interaction of environmental
and genetic risk factors
DEFINITION
Sudden Infant Death Syndrome (SIDS) is a medical term that describes
the sudden death of an infant which remains unexplained after all
known and possible causes have been carefully ruled out through
autopsy, death scene investigation, and review of the medical history
EPIDEMIOLOGY
SIDS is responsible for more deaths than any
other cause in childhood for babies one month
to one year of age, claiming - 7,000 babies
each year -nearly one baby every hour of every
day
EPIDEMIOLOGICAL FACTS
Strikes families of all races, ethnic and
socioeconomic origins without warning; neither
parent nor physician can predict that something
is going wrong. In fact, most SIDS victims appear
healthy prior to death
DEMOGRAPHY
1.Sids is less frequent in the 1st month of life
2.Peak month of occurance is between 2-4 month
3.Boys are more likely to be affected than girls
4.Low socioeconomic stance enhances SIDS Occurance
What Causes SIDS?
No adequate medical explanations for SIDS
deaths, current theories include:
*Tobacco, cocaine and heroin use by mothers during pregnancy
puts the infant at a higher risk for SIDS.
*Infants who sleep on their sides and stomachs have a higher risk
of SIDS than babies who sleep on their backs. (Remember to lay
the baby BACK to bed)
*Babies born to teenage mothers have a higher risk of SIDS than
babies who are born to older mothers.
PATHOPHYSIOLOGY
Multifactorial in origin
Triple Risk Hypothesis
Vulnerable infant
Critical developmental period in homeostatic control
Exogenous stressors
Final pathway believed to involve immature cardiorespiratory and autonomic
control along with failure of arousal responsiveness from sleep
SIDS FINDINGS
External Appearance:
*Normal state of hydration & nutrition
*Small amount of frothy fluid in or about mouth & nose
*Vomitus present
*Postmortem lividity &/or rigors
*Livormortis
*Disfiguration/Unusual position - dependant blood pooling/pressure
marks
Internal Appearances On Autopsy:
Pulmonary congestion & edema
Intrathoracic petechiae 90% of time
Stomach contents in trachea
RISKS FACTORS DIVIDED INTO:
SOCIAL FACTORS
Increased risk with:
Lower socioeconomic
status
Younger maternal age
Lower maternal education
MOTHER RELATED FACTORS
Mothers of SIDS infants:
Less prenatal care
Low birth weight
Preterm birth
IUGR
Shorter intervals between
pregnancies (< 18 mo)
SMOKING
OVER HEATING
PRONE SLEEPING
WHEN THE CHILD IS IN PRONE POSITION
SUBSTANCE USE AS A PREDISPOSING FACTOR
GENETICS RISK
FACTORS
Sodium and Potassium channel
polymorphisms associated with long QT
syndrome
Polymorphisms in serotonin
transporter (5-HTT) gene
DIAGNOSIS
By definition, SIDS is a diagnosis of exclusion
 declaration of Sids is made after:
 Complete autopsy, Investigation of child’s death
scene.
RISK REDUCTION
POSSIBLE MEASURES TO BE
TAKEN INCLUDE:
BACK TO SLEEP IS PARAMOUNT
HARD
Surface
Sleeping clothes
PROTECTIVE GUARD
DO NOT SMOKE DURING PREGNANCY AND AROUND THE INFANT
AVIOD OVERHEATING THE BABY’S
SURROUNDING
BREAST FEED THE INFANT
GET A SEPARATE BED FOR THE INFANT
CONCLUSIONS
SIDS is:
 Major cause of death in infants after 1st
month of life
 Sudden & silent in an apparently healthy
infant
 Unpredictable & unpreventable
 Quick death with no signs of suffering -
usually during sleep
REFERENCE
Hunt CE, Hauck FR. Sudden infant death syndrome. Cmaj. Jun 20
2006;174(13):1861-1869.
Moon RY, Horne RS, Hauck FR. Sudden infant death syndrome. Lancet.
Nov 3 2007;370(9598):1578-1587.
Weese-Mayer DE, Ackerman MJ, Marazita ML, Berry-Kravis EM. Sudden
Infant Death Syndrome: review of implicated genetic factors. Am J Med
Genet A. Apr 15 2007;143A(8):771-788.
Gurbutt D, Gurbutt R. Risk reduction and sudden infant death syndrome.
Community Pract. Jan 2007;80(1):24-27.
Fleming P, Blair PS. Sudden Infant Death Syndrome and parental smoking.
Early Hum Dev. Nov 2007;83(11):721-725.
Damato EG. Safe sleep: can pacifiers reduce SIDS risk? Nurs Womens
Health. Feb 2007;11(1):72-76.
THANK YOU FOR YOUR ATTENTION

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Sids ruben copy

  • 1. MINISTRY OF HEALTH OF UKRAINE LUGANSK STATE MEDICAL UNIVERSITY DEPARTMENT OF PEDIATRICS REPORT PRESENTED BY RUBEN GOMBALANDI . SUPERVISED BY ASST.PROF. OKSANA BABINOVA. ON
  • 2. Lool at this cute being!!!!!
  • 3. The next morning ,you find this!!!!!!!!!!!!!!!!!!
  • 4. INTRODUCTION Sudden infant death syndrome continues to be the most common cause of post neonatal death, account for 25% of all death between 1month of age and 1 year of Age. SIDS Goes , by different names ‘’COT Death , Cribs. Some environmental risk factors are modifiable Reducing exposure to modifiable risk factors has lowered the incidence of SIDS New research indicates genetic risk factors Actual risk of SIDS may depend on interaction of environmental and genetic risk factors
  • 5. DEFINITION Sudden Infant Death Syndrome (SIDS) is a medical term that describes the sudden death of an infant which remains unexplained after all known and possible causes have been carefully ruled out through autopsy, death scene investigation, and review of the medical history
  • 6. EPIDEMIOLOGY SIDS is responsible for more deaths than any other cause in childhood for babies one month to one year of age, claiming - 7,000 babies each year -nearly one baby every hour of every day
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  • 8. EPIDEMIOLOGICAL FACTS Strikes families of all races, ethnic and socioeconomic origins without warning; neither parent nor physician can predict that something is going wrong. In fact, most SIDS victims appear healthy prior to death
  • 9. DEMOGRAPHY 1.Sids is less frequent in the 1st month of life 2.Peak month of occurance is between 2-4 month 3.Boys are more likely to be affected than girls 4.Low socioeconomic stance enhances SIDS Occurance
  • 10. What Causes SIDS? No adequate medical explanations for SIDS deaths, current theories include: *Tobacco, cocaine and heroin use by mothers during pregnancy puts the infant at a higher risk for SIDS. *Infants who sleep on their sides and stomachs have a higher risk of SIDS than babies who sleep on their backs. (Remember to lay the baby BACK to bed) *Babies born to teenage mothers have a higher risk of SIDS than babies who are born to older mothers.
  • 11. PATHOPHYSIOLOGY Multifactorial in origin Triple Risk Hypothesis Vulnerable infant Critical developmental period in homeostatic control Exogenous stressors Final pathway believed to involve immature cardiorespiratory and autonomic control along with failure of arousal responsiveness from sleep
  • 12. SIDS FINDINGS External Appearance: *Normal state of hydration & nutrition *Small amount of frothy fluid in or about mouth & nose *Vomitus present *Postmortem lividity &/or rigors *Livormortis *Disfiguration/Unusual position - dependant blood pooling/pressure marks Internal Appearances On Autopsy: Pulmonary congestion & edema Intrathoracic petechiae 90% of time Stomach contents in trachea
  • 13. RISKS FACTORS DIVIDED INTO: SOCIAL FACTORS Increased risk with: Lower socioeconomic status Younger maternal age Lower maternal education MOTHER RELATED FACTORS Mothers of SIDS infants: Less prenatal care Low birth weight Preterm birth IUGR Shorter intervals between pregnancies (< 18 mo)
  • 17. WHEN THE CHILD IS IN PRONE POSITION
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  • 19. SUBSTANCE USE AS A PREDISPOSING FACTOR
  • 20. GENETICS RISK FACTORS Sodium and Potassium channel polymorphisms associated with long QT syndrome Polymorphisms in serotonin transporter (5-HTT) gene
  • 21. DIAGNOSIS By definition, SIDS is a diagnosis of exclusion  declaration of Sids is made after:  Complete autopsy, Investigation of child’s death scene.
  • 22. RISK REDUCTION POSSIBLE MEASURES TO BE TAKEN INCLUDE:
  • 23. BACK TO SLEEP IS PARAMOUNT HARD Surface Sleeping clothes PROTECTIVE GUARD
  • 24. DO NOT SMOKE DURING PREGNANCY AND AROUND THE INFANT
  • 25. AVIOD OVERHEATING THE BABY’S SURROUNDING
  • 26. BREAST FEED THE INFANT
  • 27. GET A SEPARATE BED FOR THE INFANT
  • 28. CONCLUSIONS SIDS is:  Major cause of death in infants after 1st month of life  Sudden & silent in an apparently healthy infant  Unpredictable & unpreventable  Quick death with no signs of suffering - usually during sleep
  • 29. REFERENCE Hunt CE, Hauck FR. Sudden infant death syndrome. Cmaj. Jun 20 2006;174(13):1861-1869. Moon RY, Horne RS, Hauck FR. Sudden infant death syndrome. Lancet. Nov 3 2007;370(9598):1578-1587. Weese-Mayer DE, Ackerman MJ, Marazita ML, Berry-Kravis EM. Sudden Infant Death Syndrome: review of implicated genetic factors. Am J Med Genet A. Apr 15 2007;143A(8):771-788. Gurbutt D, Gurbutt R. Risk reduction and sudden infant death syndrome. Community Pract. Jan 2007;80(1):24-27. Fleming P, Blair PS. Sudden Infant Death Syndrome and parental smoking. Early Hum Dev. Nov 2007;83(11):721-725. Damato EG. Safe sleep: can pacifiers reduce SIDS risk? Nurs Womens Health. Feb 2007;11(1):72-76.
  • 30. THANK YOU FOR YOUR ATTENTION