The document discusses several plant-derived compounds, the plant species they are biosynthesized in, and their typical site of accumulation. Some examples mentioned are shikonin from lithospermum which is biosynthesized and accumulates in the root, and nicotine from nicotiana which is biosynthesized in the root but accumulates throughout the whole plant. It also lists some challenges with plant-derived compounds, such as plants needing to reach maturity, difficulties increasing plantation areas, and limited natural resources and harvesting.