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Paramedic Inter Facility
Transfer
Training
MEDICATION
CLASSIFICATIONS
Medication and Transport
• Most PIFT medications are not found in
the National Standard Curriculum for
Paramedic
• Medications usually found being
administered to critical care patients
CLASSIFICATIONS OF
MEDICATIONS
18 classifications of
drugs plus OTC
medications
CLASSIFICATIONS OF
MEDICATIONS
• Anticoagulants
• Anticonvulsants
• Antidiabetics
• Antidysrhythmics
• Antihypertensives
• Anti-infectives
• Antipsychotics
• Cardiac glycosides
• Corticosteroids
• Drotrecogin
• GI Agents
• IV fluids
• Narcotics
• Parenteral Nutrition
• Platelet Aggregation Inhibitors
• Respiratory Medications
• Sedatives
• Vasoactive Agents
ALLERGIC REACTIONS
• All medications have the
potential to create an
allergic reaction
• Be vigilant for signs of
allergic reactions or
anaphylaxis
• Treat according to
MEMS protocol
• OK, let’s look at the drug
classifications in the PIFT program
ANTICOAGULANTS
• Used to prevent extension of existing
clot or formation of new blood clots
• Does not dissolve existing clots
• Patients may be on these drugs for
extended periods of time
• PATIENTS ON ANTICOAGULANTS
• MI or suspected MI patients
• DVT—deep vein thrombosis
• pulmonary embolism
• DIC—disseminated intravascular
coagulation
• Other clotting-related disorders
ANTICOAGULANTS
• Most commonly used anticoagulants:
• Heparin
• Lovenox (Enoxaparin)
ANTICOAGULANTS
Generally administered IV but in certain
cases may be given SQ
• What to watch for:
• Signs of bleeding, either internally or
externally
• Monitor vitals frequently
• Signs and symptoms of shock
• Altered level of consciousness
ANTICOAGULANTS
• Potential interventions in case of
adverse reaction:
• Consider discontinuing drug
• Control any external bleeding
• Treat for shock
• Consider contacting medical control
ANTICOAGULANTS
THROMBOLYTICS
• Paramedics are not permitted to
transport patients with thrombolytic
drugs running
• BUT…..
– Paramedics may transport patients shortly
after completion of thrombolytic therapy.
– These patients may present in several
different ways…
• Patients may have received
thrombolytics for either an acute MI or
non-hemorrhagic CVA
• Patients have reperfused and have
improved OR…
• Failed perfusion and continue to show
symptoms
THROMBOLYTICS
• What to watch for during transport:
–Signs of bleeding
• Particularly intracranial or GI bleeding
–Signs of shock
–Altered level of consciousness
–Hypotension
–Dysrhythmias
THROMBOLYTICS
• Potential interventions for adverse
reactions:
–Treat dysrhythmias as per Maine EMS
protocols
–General supportive measures
–Consider fluids for hypotension
–Contact OLMC for options including
diversion
THROMBOLYTICS
ANTICONVULSANTS
• Used primarily to prevent or treat
seizures
• Seizures are often associated with
epilepsy, head injury, fever, infection or
unknown etiology
ANTICONVULSANTS
• Anticonvulsants consist of
three types of drugs:
1.Benzodiazepines
2.Barbiturates
3.Dilantin or Cerebyx
• BENZODIAZEPINES:
–Lorazepam (Ativan)
–Midazolam (Versed)
–Diazepam (Valium)
ANTICONVULSANTS
ANTICONVULSANTS
•May be administered IV, IM,
PO or rectally in infants
•Usually administered by IV
infusion pump during
interfacility transport
• Barbiturate of choice for many years
has been PHENOBARBITAL
• DILANTIN (phenytoin) and CEREBYX
(fosphenytoin) are also frequently used
to suppress and/or control seizure
activity
ANTICONVULSANTS
• It is not uncommon to see 2 or more
different anticonvulsants used in
combination during interfacility
transport
• Doses may have to be altered during
transport due to increased seizure
activity
ANTICONVULSANTS
• What to watch for:
–Hypotension
–Respiratory depression
–Vomiting
–Bradycardia and other
dysrhythmias
–Increased seizure activity
ANTICONVULSANTS
• Potential interventions in case of
adverse reaction:
• Consider discontinuing drug or drugs
• Consider fluids for hypotension
• Support ventilations as necessary
• Treat dysrhythmias per Maine EMS
protocols
• If increased seizure activity occurs,
consider increasing dosage if permitted by
transfer order or contact OLMC
ANTICONVULSANTS
ANTIDIABETICS
• In the context of interfacility transport,
it is not uncommon to encounter
patients that require treatment with
antidiabetic agents
• In most cases, the medication that you
will be monitoring or administering will
be INSULIN.
• Patients will generally have a
diagnosis of:
–Hyperglycemia
–Hyperglycemic coma
–Hyperosmolar hyperglycemic
nonketotic coma
ANTIDIABETICS
• INSULIN comes in many forms. They are
generally either rapid, intermediate or long
acting preparations.
• Common names include the following:
– Humulin
– Novolin
– NPH
– Iletin
– Lantus
ANTIDIABETICS
• Administration will generally be by
IV infusion in the interfacility mode
but…
–In some long distance transfers it may
be necessary to administer the patient’s
routine dose of insulin by subcutaneous
injection
ANTIDIABETICS
• Blood glucose monitoring may be
necessary depending on the patient’s
condition and the length of the transfer
ANTIDIABETICS
• What to watch for during transport:
–Seizures
–Alterations in blood glucose
– Signs and symptoms of hypoglycemia
• Nausea, anxiety, altered level of
consciousness, tachycardia, diaphoresis
ANTIDIABETICS
• Potential interventions:
–Treat hypoglycemia or seizures as per
Maine EMS protocols
–Consider discontinuing or altering the
infusion rate of insulin as per OLMC
–Provide general supportive measures
ANTIDIABETICS
ANTIDYSRHYTHMICS
This is the largest classification
of medication in the PIFT
module as it contains several
sub-classifications
• Contained within this section are the
following sub-classes of medications:
– Beta Blockers
– Calcium Channel Blockers
– Cardiac Glycosides
– Miscellaneous Antidysrhythmics such as:
• Amiodarone (Cordarone)
• Magnesium sulfate
• Procainamide (Pronestyl)
• Phenytoin (Dilantin)
• Lidocaine
ANTIDYSRHYTHMICS
NOTE
• Certain medications will appear in
several different classifications during
this program as some of them are
indicated for different medical
conditions.
– Ex. Beta blockers and calcium channel
blockers appear in this section as
antidysrhythmic agents but will also be seen
in the section on Antihypertensives
• What kinds of patients will we see on
antidysrhythmic medications?
– CARDIAC PATIENTS
• Confirmed or suspected MIs
• Angina
• Tachydysrhythmias
• Bradydysrhythmias with or without heart blocks
• Atrial fibrillation and flutter
• PVCs and other ectopic conditions
ANTIDYSRHYTHMICS
BETA BLOCKERS
Metoprolol (Lopressor)
Propranolol (Inderal)
Atenolol (Tenormin)
Esmolol (Brevibloc)
• During transport primarily used to treat
various tachydysrhythmias, atrial fibrillation
and atrial flutter
• Used to treat MIs but generally given in
hospital prior to transfer
CALCIUM CHANNEL BLOCKERS
Diltiazem (Cardizem)
Verapamil (Calan)
Nifedipine (Procardia)
•Treatment of tachydysrhythmias,
atrial fibrillation and flutter
CARDIAC GLYCOSIDES
Digoxin (Lanoxin)
• Treatment of tachydysrhythmias,
particularly to control ventricular
rate in atrial fibrillation or flutter;
PSVT
AMIODARONE
• Generally used to treat atrial and
ventricular tachydysrhythmias during
interfacility transport
LIDOCAINE
• Used to treat wide complex
tachycardia and ventricular ectopy
ROUTES OF ADMINISTRATION
•Antidysrhymics will almost always
be administered IV by infusion
pump
• WHAT TO WATCH FOR DURING
TRANSPORT:
–Dysrhythmias
–Altered levels of consciousness
–Hypotension/changes in vital signs
–Seizures
ANTIDYSRHYTHMICS
• Potential interventions in case of
adverse or allergic reaction:
– Treat dysrhythmias and seizures per Maine
EMS protocols
– Consider fluids for hypotension if not
contraindicated by patient’s condition
– OLMC for option of discontinuing drug,
adjusting dosage or diversion
– General supportive measures
ANTIDYSRHYTHMICS
• KEEP IN MIND THAT ALL PATIENTS ON
CARDIAC MEDICATIONS SHOULD BE
TRANSPORTED ON A CARDIAC
MONITOR
• Record any changes in rhythm
• Take frequent vitals
ANTIDYSRHYTHMICS
• REMEMBER THAT CARDIAC PATIENTS
CAN DETERIORATE QUICKLY AND
YOU MUST BE PREPARED FOR A
CODE OR OTHER SERIOUS EVENT AT
ALL TIMES
ANTIDYSRHYTHMICS
ANTI-INFECTIVES
• Includes the following:
• Antibiotics
• Antivirals
• Antifungal agents
Rarely will we see an antiviral or
antifungal agent on an interfacility
transfer
• What types of patients can we expect to
see on anti-infectives?
• Pneumonia/respiratory infections
• Meningitis
• Sepsis
• Cellulitis
• UTI
• Various infectious diseases
ANTI-INFECTIVES
• Most common medications used in
transport:
• Vancomycin
• Rocephin
• Penicillin
• Cefazolin (Ancef)
• Gentamicin
ANTI-INFECTIVES
Almost always administered IV
ANTI-INFECTIVES
• What to look for:
• Signs and symptoms of allergic
reaction
• Induration or redness at the IV site
• Altered level of consciousness
• Nausea/vomiting
ANTI-INFECTIVES
• Note:
–Antibiotics have a greater potential
for allergic reactions than any other
drugs
ANTI-INFECTIVES
ANTIHYPERTENSIVES
• These medications are essentially used to
control hypertensive crisis of various
etiologies
• Included within the classification of
antihypertensives are several other
classes of medications that have
antihypertensive action
• Other classifications and subclassifications
of antihypertensives include:
– ACE Inhibitors
– Beta Blockers
– Alpha Blockers
– Calcium Channel Blockers
– Diuretics
– Vasodilators
ANTIHYPERTENSIVES
COMMONLY USED
ANTIHYPERTENSIVES
COMMONLY USED
ANTIHYPERTENSIVES
• ACE Inhibitors
•Benazepril (Lotensin)
•Enalapril (Vasotec)
•Lisinopril (Zestril)
•Captopril (Capoten)
• Alpha Blockers
–Doxazosin (Cardura)
–Prazosin (Minipress)
–Terazosin (Hytrin)
ANTIHYPERTENSIVES
• Beta Blockers
–Atenolol (Tenormin)
–Propranolol (Inderal)
–Metoprolol (Lopressor)
–Labetalol (Normodyne)
ANTIHYPERTENSIVES
• Calcium Channel Blockers
–Diltiazem (Cardizem)
–Verapamil (Calan)
–Nifedipine (Procardia)
–Amlodipine (Norvasc)
ANTIHYPERTENSIVES
• Diuretics
–Furosemide (Lasix)
–Bumetadine (Bumex)
–Torsemide (Demadex)
ANTIHYPERTENSIVES
• Vasodilators
–Hydralazine (Apresoline)
–Minoxidil (Loniten)
–Nitroglycerin
ANTIHYPERTENSIVES
• Routes of Administration:
–Generally IV but may be given PO in
certain cases on long transfers
ANTIHYPERTENSIVES
• What to watch for during transport
–Severe hypotension
–Nausea/vomiting
–Symptomatic bradycardia
–Other dysrhythmias
ANTIHYPERTENSIVES
• Possible interventions when adverse
reactions occur during transport:
–Treat bradycardia and other
dysrhythmias as per Maine EMS
protocols
–Consider fluids for hypotension if not
contraindicated by patient condition
ANTIHYPERTENSIVES
• Possible Interventions when adverse
reactions occur during transport:
–Consider promethazine ( Phenergan )
for nausea
–Contact OLMC for options of
discontinuing medication, altering
dosage or diversion
ANTIHYPERTENSIVES
• All patients on antihypertensive
medications should be
transferred on a cardiac
monitor
• Take frequent vitals
ANTIHYPERTENSIVES
BREAK
SCENARIO 1
• You are transporting a cardiac patient from a
local community hospital to Eastern Maine
Medical Center. The patient has a diagnosis
of unstable angina. Transport time to EMMC
is approximately 90 minutes.
• As you left the sending facility, the patient
had the following vitals:
• HR---76 BP---122/76 R---18
• Medications
– Oxygen at 4 lpm via nc
– Nitroglycerine IV 14 mcg/min
– Heparin IV 1000u/hour
– Aggrastat IV 80mcg/min
– You also have orders for Morphine 2-5 mg
prn for pain management
SCENARIO 1
• 30 minutes into the transfer your
patient begins to appear anxious,
becomes slightly diaphoretic, and
complains of some SOB.
• You take a new set of vitals:
–HR---104
–BP---96/62
–R-----20
SCENARIO 1
1. What do you suspect?
2. What action would you take?
3. What questions do you have
for medical control?
SCENARIO 1
ANTIPSYCHOTICS
• The number of psychiatric transfers
has increased dramatically in recent
years
• A many patients are transferred with
chemical restraints and sometimes
need to be given additional medication
during transport
• Medication is administered to control
psychotic behavior that is otherwise
difficult to manage in an ambulance
• Patients will have a number of different
diagnoses including agitation,
schizophrenia, depression, delusional
disorders, etc.
ANTIPSYCHOTICS
A number of different
medications are used to
provide chemical restraint
ANTIPSYCHOTICS
• Common Chemical Restraint
Medications:
–Haloperidol (Haldol)
–Chlorpromazine (Thorazine)
–Risperidone (Risperdal)
–Benzodiazepines (Diazepam,
Lorazepam, Midazolam)
CHEMICAL RESTRAINT
• These drugs may be given alone or in
combination with other antipsychotic
drugs
• May also be administered in
combination with other medications
such as diphenhydramine (Benadryl)
for added sedative effect
CHEMICAL RESTRAINT
• Routes of administration
–Generally given IV but may be given IM
or PO in some cases
–For IV medication, the patient should
leave the hospital with a saline lock in
place if possible
ANTIPSYCHOTICS
• Considerations…
– Discuss all medication issues with the
sending physician before leaving the
hospital
– If the patient is sedated upon your arrival,
ask if the drug will last long enough for
you to reach your destination
• Transfers of more than 2 hours are not
uncommon
ANTIPSYCHOTICS
• Considerations…
–If medication will be needed during
transport, do not wait until the patient
becomes disruptive and combative
–Make sure that any patient who is
medicated or may require medication
during transport is “Blue papered”
ANTIPSYCHOTICS
• What to watch for during transport:
–Respiratory depression
–Hypotension
–Seizures
–Extrapyramidal reactions
• Agitation, muscle tremor, drooling,
tremors, etc.
ANTIPSYCHOTICS
• Potential interventions in cases of
adverse or allergic reactions:
– Treat allergic reactions and seizures as per
Maine EMS protocols
– Support ventilations as necessary and be
prepared to intubate
– Consider fluids for hypotension
– Diphenhydramine for extrapyramidal reactions
– OLMC for other options including diversion
ANTIPSYCHOTICS
CARDIAC GLYCOSIDES
• These are essentially digitalis
preparations
–The most commonly used drug is digoxin
(Lanoxin)
–Generally used to treat atrial fibrillation,
atrial flutter or atrial tachycardias
–Sometimes used to treat CHF
Route of Administration:
• Generally IV infusion
CARDIAC GLYCOSIDES
• What to watch for during transport:
–Dysrhythmias including heart blocks
–Cardiac arrest
–Nausea/vomiting
–Digitalis toxicity
CARDIAC GLYCOSIDES
• Potential interventions for adverse
reactions:
–Treat all dysrhythmias per Maine EMS
protocols
–Consider promethazine for
nausea/vomiting
–Contact OLMC for options of
discontinuing drug, altering dose or
diversion
CARDIAC GLYCOSIDES
• All patients on cardiac glycosides
must be transported on a cardiac
monitor and watched carefully for
developing adverse reactions
CARDIAC GLYCOSIDES
CORTICOSTEROIDS
• Medications in this class are primarily
used to treat the following:
– Cerebral edema associated with head injury
– Status asthmaticus
– To suppress the immune system in cases of
severe allergic reactions/anaphylactic shock
– Chronic inflammatory conditions
• Routes of administration:
–IV infusion in most cases
–Also used in inhaled form for certain
respiratory conditions
CORTICOSTEROIDS
• Commonly used medications in
this class
–Betamethasone (Celestone)
–Dexamethasone (Decadron)
–Methylprednisolone (Solu-Medrol)
–Hydrocortisone (Solu-Cortef)
CORTICOSTEROIDS
• Also in inhaled form…
–Beclomethasone (Beconase, Beclovent)
–Triamcinolone (Azmacort, Kenalog)
–Flunisolide (Aerobid)
CORTICOSTEROIDS
• What to watch for during
transport:
–Hypertension
–Nausea/vomiting
–CHF
CORTICOSTEROIDS
• Potential interventions in case of
adverse reactions:
–Follow Maine EMS protocols for allergic
reactions, CHF or nausea/vomiting
–Contact OLMC for options of
discontinuing drug
CORTICOSTEROIDS
DROTRECOGIN
• An antisepsis agent
• Used to treat severe sepsis or septic
shock
• Administered by IV infusion only
• What to watch for during
transport:
–Be alert for signs of internal
bleeding
–Shock symptoms
DROTRECOGIN
• Potential interventions during
transport :
–Treat for shock
–Contact OLMC for option of
discontinuing drug
DROTRECOGIN
GASTROINTESTINAL AGENTS
• Used to treat a variety of GI
disorders
• Several different sub-
classifications of GI medications:
1. Proton Pump Inhibitors
2. Somatostatin Analogues
3. H2 Blockers
4. Anti-emetics
• Commonly used drugs:
–Protonix
–Prevacid
Protein Pump Inhibitors
• Commonly used drug:
–Sandostatin
Somatostatin Analogues
• Commonly used drug:
–Famotidine (Pepcid)
–Cometidine (Tagamet)
H2 Blockers
Anti-emetics
• metoclopramide (Reglan)
• ondansetron (Zofran)
• prochlorperazine (Compazine)
• What kind of patients will we see being
transported on these medications?
–Active duodenal or gastric ulcers
–GERD—gastric esophageal reflux
disease
–Upper GI bleed
–Esophageal varices
GASTROINTESTINAL AGENTS
• Routes of Administration:
–IV infusion
–PO
GASTROINTESTINAL AGENTS
• What to watch for during transport:
–Adverse reactions are rare but may
consist of dysrhythmias
–Hypoglycemia is possible but will
probably only be seen on longer
transfers
GASTROINTESTINAL AGENTS
• Potential interventions for adverse
or allergic reactions:
–Treat dysrhythmias and hypoglycemia
per Maine EMS protocols
–Consider termination of drug
–OLMC for further options
GASTROINTESTINAL AGENTS
IV FLUIDS
• Consists of a wide variety of fluids
including the following:
–Normal saline, ½ NS
–Lactated Ringers
–D5W and D10W
–Dextran, Plasmanate
–Hetastarch, albumin
• Why do we give IV fluids during
transport?
–Increase or maintain blood volume and
blood pressure
–Maintain hydration
–Access for medication
–Treat hypoglycemia (D10W)
IV FLUIDS
• What to watch for during transport:
–Signs of fluid overload
–Edema
–Pulmonary edema
–Take vitals often to monitor BP
IV FLUIDS
• Potential interventions in cases of
adverse reactions:
–Consider discontinuing or reducing
rate of infusion
–Treat CHF per Maine EMS
protocols
IV FLUIDS
ELECTROLYTES
• Electrolytes consist of the following:
–Potassium
–Calcium
–Sodium chloride
–Sodium bicarbonate (alkalizing agent)
• What type of patients will we see who
require electrolyte therapy?
–Patients requiring potassium
supplementation due to deficiency
diseases when oral replacement is not
feasible
–Those who have lost potassium due to
severe vomiting or diarrhea
ELECTROLYTES
• What type of patients will we see who
require electrolyte therapy?
–Patients with severe hypocalcemia
–Sodium depletion
–Patients requiring sodium bicarbonate to
treat hyperacidity or metabolic acidosis
due to shock or dehydration
ELECTROLYTES
• Route of administration:
–Primarily IV infusion
ELECTROLYTES
• What to watch for during transport:
–Dysrhythmias
–Seizures
–Signs and symptoms of allergic
reactions (rare)
ELECTROLYTES
• Potential interventions in cases of
adverse reactions:
–Treat seizures and dysrhythmias per
Maine EMS protocols
–Consider option of discontinuing drug or
modifying dose as per OLMC or transfer
orders
ELECTROLYTES
NARCOTICS
• Used to control moderate to severe
pain
• May be administered by IV infusion
pump but may also be given by IV or IM
injection as per transfer order
• Commonly used narcotics:
–Fentanyl
–Morphine
–Hydromorphone (Dilaudid)
–Meperidine (Demerol)
–Pentazocine (Talwin)
NARCOTICS
• What to watch for during transport:
–Respiratory depression
–Hypotension
–Nausea/vomiting
–Bradycardia
NARCOTICS
• Potential interventions in cases of
adverse reactions:
–Consider discontinuing medication
–Treat dysrhythmias per Maine EMS
protocols
–Consider Naloxone
–Assist ventilations as necessary and be
prepared to intubate
NARCOTICS
PARENTERAL NUTRITION
• Used to treat the following:
–Patients requiring nutrition who are
unable to take food and/or fluids by
mouth
–Patients requiring vitamin supplements
to prevent or treat vitamin deficiency
conditions
• Common forms include the following:
–Vitamin solutions
–TPN (Total Parenteral Nutrition)
• An individualized solution designed to meet
the needs of the patient
PARENTERAL NUTRITION
• What to watch for during transport:
–Adverse or allergic reactions are rare
but have been seen
–Hypoglycemia
• Can occur since most TPN preparations
contain Insulin
PARENTERAL NUTRITION
• Potential interventions in case of
adverse reactions:
–Treat hypoglycemia as per Maine EMS
protocols
–Consider discontinuing drug
PARENTERAL NUTRITION
GLYCOPROTEIN
IIb/IIa Platelet Inhibitors
• What are these drugs all about?
–They are potent agents that inhibit
platelets from aggregating or clumping
together in the context of coronary
artery disease.
–Frequently used in combination with
Heparin
• Patients being transported on these
drugs
– Acute MI
– Unstable angina
– Acute coronary syndrome
– Many of these patients are being transported
to the cath lab for diagnostic and/or
interventional catherization---angioplasty
GLYCOPROTEIN
IIb/IIa Platelet Inhibitors
• Route of Administration:
–IV infusion only
GLYCOPROTEIN
IIb/IIa Platelet Inhibitors
• What to watch for during transport:
–Any signs of bleeding
–Signs and symptoms of shock
–Changes in level of consciousness
GLYCOPROTEIN
IIb/IIa Platelet Inhibitors
• Potential interventions in cases of
adverse or allergic reactions:
– Control any external bleeding
– Treat for shock as needed
– Contact OLMC for options of discontinuing
drug, altering dose or diversion
– In cases of suspected bleeding, the provider
may also have to D/C heparin if it is also
being administered
– Treat dysrhythmias and allergic reactions as
per Maine EMS protocols
GLYCOPROTEIN
IIb/IIa Platelet Inhibitors
MULTIPLE MEDICATIONS
• Keep in mind that you will often be
transporting patients on 2, 3 or even
more medications
– Eg.: It is common to transport a cardiac
patient on nitroglycerin, Heparin and
Aggrastat with an order to administer Fentanyl
for pain as needed.
SCENARIO 2
• We have discussed the option of
diversion to a nearby hospital in almost
each of the classifications that we have
examined
• This is often a difficult decision to
make for a number of reasons
• What are the potential benefits of
diversion?
• What are the potential negative aspects
of diversion?
• What factors should be considered in
deciding to divert?
• Can you divert without authorization
from OLMC?
SCENARIO 2
• DIVERSION CONSIDERATIONS
–Patient condition
–Transfer orders
–Ability to treat
–Distance to receiving or sending
facility
–Consult with OLMC
–Comfort level of paramedic
SCENARIO 2
RESPIRATORY MEDICATIONS
• Within this classification are several
subclassifications of drugs that are used in
treating patients with respiratory conditions
– Beta agonists
– Anticholinergics
– Steroids
– Mucolytics
– Miscellaneous
• Albuterol (Proventil)
• Terbutaline
• Metaproterenol (Alupent)
• Piruterol (Maxair)
BETA AGONISTS
These drugs provide relief through bronchodilation
ANTICHOLINERGICS
• Ipratropium (Atrovent)
These drugs provide long term
maintenance of bronchodilation
STEROIDS
• Beclomethasone (Beclovent)
• Flunisolide (AeroBid)
• Fluticasone (Flovent)
• Triamcinolone (Azmacort)
These drugs provide relief by reducing
inflammation
MISCELLANEOUS
• Aminophylline
• Montelukast (Singulair)
• What kinds of patients will you be
transporting on respiratory
medications?
– The respiratory problem may be primary or
secondary
– Acute or chronic
RESPIRATORY MEDICATIONS
• Asthma
• COPD
• Emphysema
• Certain cases of allergic reaction
RESPIRATORY MEDICATIONS
• Routes of administration:
–Most of these drugs will be administered
by inhaler or nebulized
• Aminophylline is given by IV infusion
• Terbutaline may be IV or by inhalation
• Is epinephrine a respiratory medication?
RESPIRATORY MEDICATIONS
• Transport respiratory medication
patients on cardiac monitor
RESPIRATORY MEDICATIONS
• What to watch for during transport:
–Dysrhythmias
• Beta agonists such as Albuterol can
cause tachydysrhythmias
–Palpitations, chest pain
RESPIRATORY MEDICATIONS
• Potential interventions in case
of adverse reaction:
–Treat dysrhythmias and chest pain
per Maine EMS protocols
RESPIRATORY MEDICATIONS
SEDATIVES
• Sedatives consist of a variety of
medications from several different
classifications (Some that we have
already reviewed)
– Narcotics
– Benzodiazepines
– Antipsychotics
– Barbiturates and anesthetics
• Narcotics
– Fentanyl, morphine, dilaudid, meperidine, etc.
• Benzodiazepines
– Diazepam, lorazepam, midazolam
• Antipsychotics
– Haloperidol, risperidone, chlorpromazine, etc.
• Barbiturates
– Phenobarbital, thiopental, amobarbital
• Anesthetics
– Etomidate, propofol
SEDATIVES
• NOTE: Paramedics will not
transport patients on anesthetics
unless accompanied by an RN
–Most patients on anesthetics are
intubated
SEDATIVES
• Types of patients on sedatives…
–Agitation and combativeness associated
with head injury, psychosis, etc.
–Control of seizure activity
–Any condition where it is necessary to
provide sedation
SEDATIVES
• What to watch for during transport:
–Respiratory depression
–Hypotension
–Bradycardia
SEDATIVES
• Potential interventions in cases of
adverse reactions:
–Oxygen, Support ventilations as
necessary and be prepared to intubate
–Treat bradycardia per Maine EMS
protocols
–Consider fluids for hypotension
–OLMC for other options
SEDATIVES
• Take vitals often
• Transport on cardiac monitor
SEDATIVES
VASOACTIVE AGENTS
• These are medications that have an
effect on the tone and caliber or
diameter of blood vessels
– Vasopressors and sympathomimetic drugs
cause constriction of blood vessels…….
– Nitrates, vasodilators, Calcium Channel
Blockers and ACE Inhibitors cause relaxation
and dilation of vessels, thereby reducing BP
• What kinds of patients will we see on
Vasopressors and Sympathomimetics?
–Patients on these drugs are generally
being treated for hypotension and
certain types of shock
VASOACTIVE AGENTS
• Commonly used vasopressors and
sympathomimetics:
–Vasopressin (Pitressin)
–Metaraminol (Aramine)
–Dopamine (Intropin)
–Dobutamine (Dobutrex)
–Epinephrine and norepinephrine
–Isoproterenol (Isuprel)
VASOACTIVE AGENTS
• Patients taking nitrates are generally
being treated for ischemic chest
pain or hypertensive crisis
NITRATES
NITRATES
• Commonly used nitrates include:
–Nitroglycerin
–Nitroprusside (Nipride)
VASODILATORS
• Used primarily for treatment of
hypertensive crisis and
management of CHF
• Calcium Channel Blockers and ACE
Inhibitors are primarily used to treat
hypertension as we saw in the section
on Antihypertensives
VASOACTIVE AGENTS
• Routes of administration:
–IV infusion
• Usually by infusion pump
VASOACTIVE AGENTS
• What to watch for during transport:
–Severe hypotension or
hypertension
–Dysrhythmias
–Dyspnea
–Altered level of consciousness
–Nausea/vomiting
VASOACTIVE AGENTS
• Potential interventions in case of
adverse or allergic reactions:
– Treat dysrhythmias as per Maine EMS
protocols
– Consider fluids for hypotension
– Consider discontinuing drug or modifying
dose as per OLMC or transfer order
– Diversion
VASOACTIVE AGENTS
• NOTE:
–These patients must be transported on a
cardiac monitor
–Monitor vitals frequently
VASOACTIVE AGENTS
OTC MEDICATIONS
• During the course of a transport,
particularly a long distance transfer, it
may be necessary to administer certain
commonly used OTC medications
• May include medications for the
following:
• Pain (Ibuprofen, acetaminophen, etc.)
• Motion sickness (Dramamine)
• Antacids
• Antihistamines
OTC MEDICATIONS
• Guidelines for administration:
–Written order by physician that includes
name of drug, route of administration,
indication, dose and time of initial and
repeat dosing
–Drug must be supplied by the sending
facility
–Drug must have been used previously
by patient without adverse reactions
OTC MEDICATIONS
• Administration must be documented as
with all other medications
• Remember that even OTC drugs can
result in adverse or allergic reactions
so watch for any such reactions
following administration
OTC MEDICATIONS
PRESCRIPTION DRUGS
• During longer transports you may need
to administer one or more of the
patient’s regular prescription drugs
• The drug must be included in one of
the classifications that are part of the
PIFT module
CONCLUSIONS
• Be constantly alert—patients can
change in seconds
• Know your drugs---use resources
• Remember that every drug, even OTC
drugs, have the potential to result in a
serious adverse reaction
CONCLUSIONS
• Never leave the sending facility unless
you feel thoroughly comfortable with
your patient and with the medications
you are being asked to administer or
monitor
• Make sure that you are thoroughly
prepared for any complication
• Know where possible diversion
hospitals are located
• Use OLMC whenever necessary
CONCLUSIONS
Questions?

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PIFTPharmacology2_0.ppt

  • 2. Medication and Transport • Most PIFT medications are not found in the National Standard Curriculum for Paramedic • Medications usually found being administered to critical care patients
  • 4. CLASSIFICATIONS OF MEDICATIONS • Anticoagulants • Anticonvulsants • Antidiabetics • Antidysrhythmics • Antihypertensives • Anti-infectives • Antipsychotics • Cardiac glycosides • Corticosteroids • Drotrecogin • GI Agents • IV fluids • Narcotics • Parenteral Nutrition • Platelet Aggregation Inhibitors • Respiratory Medications • Sedatives • Vasoactive Agents
  • 5. ALLERGIC REACTIONS • All medications have the potential to create an allergic reaction • Be vigilant for signs of allergic reactions or anaphylaxis • Treat according to MEMS protocol
  • 6. • OK, let’s look at the drug classifications in the PIFT program
  • 7. ANTICOAGULANTS • Used to prevent extension of existing clot or formation of new blood clots • Does not dissolve existing clots • Patients may be on these drugs for extended periods of time
  • 8. • PATIENTS ON ANTICOAGULANTS • MI or suspected MI patients • DVT—deep vein thrombosis • pulmonary embolism • DIC—disseminated intravascular coagulation • Other clotting-related disorders ANTICOAGULANTS
  • 9. • Most commonly used anticoagulants: • Heparin • Lovenox (Enoxaparin) ANTICOAGULANTS Generally administered IV but in certain cases may be given SQ
  • 10. • What to watch for: • Signs of bleeding, either internally or externally • Monitor vitals frequently • Signs and symptoms of shock • Altered level of consciousness ANTICOAGULANTS
  • 11. • Potential interventions in case of adverse reaction: • Consider discontinuing drug • Control any external bleeding • Treat for shock • Consider contacting medical control ANTICOAGULANTS
  • 12. THROMBOLYTICS • Paramedics are not permitted to transport patients with thrombolytic drugs running • BUT….. – Paramedics may transport patients shortly after completion of thrombolytic therapy. – These patients may present in several different ways…
  • 13. • Patients may have received thrombolytics for either an acute MI or non-hemorrhagic CVA • Patients have reperfused and have improved OR… • Failed perfusion and continue to show symptoms THROMBOLYTICS
  • 14. • What to watch for during transport: –Signs of bleeding • Particularly intracranial or GI bleeding –Signs of shock –Altered level of consciousness –Hypotension –Dysrhythmias THROMBOLYTICS
  • 15. • Potential interventions for adverse reactions: –Treat dysrhythmias as per Maine EMS protocols –General supportive measures –Consider fluids for hypotension –Contact OLMC for options including diversion THROMBOLYTICS
  • 16. ANTICONVULSANTS • Used primarily to prevent or treat seizures • Seizures are often associated with epilepsy, head injury, fever, infection or unknown etiology
  • 17. ANTICONVULSANTS • Anticonvulsants consist of three types of drugs: 1.Benzodiazepines 2.Barbiturates 3.Dilantin or Cerebyx
  • 18. • BENZODIAZEPINES: –Lorazepam (Ativan) –Midazolam (Versed) –Diazepam (Valium) ANTICONVULSANTS
  • 19. ANTICONVULSANTS •May be administered IV, IM, PO or rectally in infants •Usually administered by IV infusion pump during interfacility transport
  • 20. • Barbiturate of choice for many years has been PHENOBARBITAL • DILANTIN (phenytoin) and CEREBYX (fosphenytoin) are also frequently used to suppress and/or control seizure activity ANTICONVULSANTS
  • 21. • It is not uncommon to see 2 or more different anticonvulsants used in combination during interfacility transport • Doses may have to be altered during transport due to increased seizure activity ANTICONVULSANTS
  • 22. • What to watch for: –Hypotension –Respiratory depression –Vomiting –Bradycardia and other dysrhythmias –Increased seizure activity ANTICONVULSANTS
  • 23. • Potential interventions in case of adverse reaction: • Consider discontinuing drug or drugs • Consider fluids for hypotension • Support ventilations as necessary • Treat dysrhythmias per Maine EMS protocols • If increased seizure activity occurs, consider increasing dosage if permitted by transfer order or contact OLMC ANTICONVULSANTS
  • 24. ANTIDIABETICS • In the context of interfacility transport, it is not uncommon to encounter patients that require treatment with antidiabetic agents • In most cases, the medication that you will be monitoring or administering will be INSULIN.
  • 25. • Patients will generally have a diagnosis of: –Hyperglycemia –Hyperglycemic coma –Hyperosmolar hyperglycemic nonketotic coma ANTIDIABETICS
  • 26. • INSULIN comes in many forms. They are generally either rapid, intermediate or long acting preparations. • Common names include the following: – Humulin – Novolin – NPH – Iletin – Lantus ANTIDIABETICS
  • 27. • Administration will generally be by IV infusion in the interfacility mode but… –In some long distance transfers it may be necessary to administer the patient’s routine dose of insulin by subcutaneous injection ANTIDIABETICS
  • 28. • Blood glucose monitoring may be necessary depending on the patient’s condition and the length of the transfer ANTIDIABETICS
  • 29. • What to watch for during transport: –Seizures –Alterations in blood glucose – Signs and symptoms of hypoglycemia • Nausea, anxiety, altered level of consciousness, tachycardia, diaphoresis ANTIDIABETICS
  • 30. • Potential interventions: –Treat hypoglycemia or seizures as per Maine EMS protocols –Consider discontinuing or altering the infusion rate of insulin as per OLMC –Provide general supportive measures ANTIDIABETICS
  • 31. ANTIDYSRHYTHMICS This is the largest classification of medication in the PIFT module as it contains several sub-classifications
  • 32. • Contained within this section are the following sub-classes of medications: – Beta Blockers – Calcium Channel Blockers – Cardiac Glycosides – Miscellaneous Antidysrhythmics such as: • Amiodarone (Cordarone) • Magnesium sulfate • Procainamide (Pronestyl) • Phenytoin (Dilantin) • Lidocaine ANTIDYSRHYTHMICS
  • 33. NOTE • Certain medications will appear in several different classifications during this program as some of them are indicated for different medical conditions. – Ex. Beta blockers and calcium channel blockers appear in this section as antidysrhythmic agents but will also be seen in the section on Antihypertensives
  • 34. • What kinds of patients will we see on antidysrhythmic medications? – CARDIAC PATIENTS • Confirmed or suspected MIs • Angina • Tachydysrhythmias • Bradydysrhythmias with or without heart blocks • Atrial fibrillation and flutter • PVCs and other ectopic conditions ANTIDYSRHYTHMICS
  • 35. BETA BLOCKERS Metoprolol (Lopressor) Propranolol (Inderal) Atenolol (Tenormin) Esmolol (Brevibloc) • During transport primarily used to treat various tachydysrhythmias, atrial fibrillation and atrial flutter • Used to treat MIs but generally given in hospital prior to transfer
  • 36. CALCIUM CHANNEL BLOCKERS Diltiazem (Cardizem) Verapamil (Calan) Nifedipine (Procardia) •Treatment of tachydysrhythmias, atrial fibrillation and flutter
  • 37. CARDIAC GLYCOSIDES Digoxin (Lanoxin) • Treatment of tachydysrhythmias, particularly to control ventricular rate in atrial fibrillation or flutter; PSVT
  • 38. AMIODARONE • Generally used to treat atrial and ventricular tachydysrhythmias during interfacility transport
  • 39. LIDOCAINE • Used to treat wide complex tachycardia and ventricular ectopy
  • 40. ROUTES OF ADMINISTRATION •Antidysrhymics will almost always be administered IV by infusion pump
  • 41. • WHAT TO WATCH FOR DURING TRANSPORT: –Dysrhythmias –Altered levels of consciousness –Hypotension/changes in vital signs –Seizures ANTIDYSRHYTHMICS
  • 42. • Potential interventions in case of adverse or allergic reaction: – Treat dysrhythmias and seizures per Maine EMS protocols – Consider fluids for hypotension if not contraindicated by patient’s condition – OLMC for option of discontinuing drug, adjusting dosage or diversion – General supportive measures ANTIDYSRHYTHMICS
  • 43. • KEEP IN MIND THAT ALL PATIENTS ON CARDIAC MEDICATIONS SHOULD BE TRANSPORTED ON A CARDIAC MONITOR • Record any changes in rhythm • Take frequent vitals ANTIDYSRHYTHMICS
  • 44. • REMEMBER THAT CARDIAC PATIENTS CAN DETERIORATE QUICKLY AND YOU MUST BE PREPARED FOR A CODE OR OTHER SERIOUS EVENT AT ALL TIMES ANTIDYSRHYTHMICS
  • 45. ANTI-INFECTIVES • Includes the following: • Antibiotics • Antivirals • Antifungal agents Rarely will we see an antiviral or antifungal agent on an interfacility transfer
  • 46. • What types of patients can we expect to see on anti-infectives? • Pneumonia/respiratory infections • Meningitis • Sepsis • Cellulitis • UTI • Various infectious diseases ANTI-INFECTIVES
  • 47. • Most common medications used in transport: • Vancomycin • Rocephin • Penicillin • Cefazolin (Ancef) • Gentamicin ANTI-INFECTIVES
  • 48. Almost always administered IV ANTI-INFECTIVES
  • 49. • What to look for: • Signs and symptoms of allergic reaction • Induration or redness at the IV site • Altered level of consciousness • Nausea/vomiting ANTI-INFECTIVES
  • 50. • Note: –Antibiotics have a greater potential for allergic reactions than any other drugs ANTI-INFECTIVES
  • 51. ANTIHYPERTENSIVES • These medications are essentially used to control hypertensive crisis of various etiologies • Included within the classification of antihypertensives are several other classes of medications that have antihypertensive action
  • 52. • Other classifications and subclassifications of antihypertensives include: – ACE Inhibitors – Beta Blockers – Alpha Blockers – Calcium Channel Blockers – Diuretics – Vasodilators ANTIHYPERTENSIVES
  • 53. COMMONLY USED ANTIHYPERTENSIVES COMMONLY USED ANTIHYPERTENSIVES • ACE Inhibitors •Benazepril (Lotensin) •Enalapril (Vasotec) •Lisinopril (Zestril) •Captopril (Capoten)
  • 54. • Alpha Blockers –Doxazosin (Cardura) –Prazosin (Minipress) –Terazosin (Hytrin) ANTIHYPERTENSIVES
  • 55. • Beta Blockers –Atenolol (Tenormin) –Propranolol (Inderal) –Metoprolol (Lopressor) –Labetalol (Normodyne) ANTIHYPERTENSIVES
  • 56. • Calcium Channel Blockers –Diltiazem (Cardizem) –Verapamil (Calan) –Nifedipine (Procardia) –Amlodipine (Norvasc) ANTIHYPERTENSIVES
  • 57. • Diuretics –Furosemide (Lasix) –Bumetadine (Bumex) –Torsemide (Demadex) ANTIHYPERTENSIVES
  • 58. • Vasodilators –Hydralazine (Apresoline) –Minoxidil (Loniten) –Nitroglycerin ANTIHYPERTENSIVES
  • 59. • Routes of Administration: –Generally IV but may be given PO in certain cases on long transfers ANTIHYPERTENSIVES
  • 60. • What to watch for during transport –Severe hypotension –Nausea/vomiting –Symptomatic bradycardia –Other dysrhythmias ANTIHYPERTENSIVES
  • 61. • Possible interventions when adverse reactions occur during transport: –Treat bradycardia and other dysrhythmias as per Maine EMS protocols –Consider fluids for hypotension if not contraindicated by patient condition ANTIHYPERTENSIVES
  • 62. • Possible Interventions when adverse reactions occur during transport: –Consider promethazine ( Phenergan ) for nausea –Contact OLMC for options of discontinuing medication, altering dosage or diversion ANTIHYPERTENSIVES
  • 63. • All patients on antihypertensive medications should be transferred on a cardiac monitor • Take frequent vitals ANTIHYPERTENSIVES
  • 64.
  • 65. BREAK
  • 66. SCENARIO 1 • You are transporting a cardiac patient from a local community hospital to Eastern Maine Medical Center. The patient has a diagnosis of unstable angina. Transport time to EMMC is approximately 90 minutes. • As you left the sending facility, the patient had the following vitals: • HR---76 BP---122/76 R---18
  • 67. • Medications – Oxygen at 4 lpm via nc – Nitroglycerine IV 14 mcg/min – Heparin IV 1000u/hour – Aggrastat IV 80mcg/min – You also have orders for Morphine 2-5 mg prn for pain management SCENARIO 1
  • 68. • 30 minutes into the transfer your patient begins to appear anxious, becomes slightly diaphoretic, and complains of some SOB. • You take a new set of vitals: –HR---104 –BP---96/62 –R-----20 SCENARIO 1
  • 69. 1. What do you suspect? 2. What action would you take? 3. What questions do you have for medical control? SCENARIO 1
  • 70. ANTIPSYCHOTICS • The number of psychiatric transfers has increased dramatically in recent years • A many patients are transferred with chemical restraints and sometimes need to be given additional medication during transport
  • 71. • Medication is administered to control psychotic behavior that is otherwise difficult to manage in an ambulance • Patients will have a number of different diagnoses including agitation, schizophrenia, depression, delusional disorders, etc. ANTIPSYCHOTICS
  • 72. A number of different medications are used to provide chemical restraint ANTIPSYCHOTICS
  • 73. • Common Chemical Restraint Medications: –Haloperidol (Haldol) –Chlorpromazine (Thorazine) –Risperidone (Risperdal) –Benzodiazepines (Diazepam, Lorazepam, Midazolam) CHEMICAL RESTRAINT
  • 74. • These drugs may be given alone or in combination with other antipsychotic drugs • May also be administered in combination with other medications such as diphenhydramine (Benadryl) for added sedative effect CHEMICAL RESTRAINT
  • 75. • Routes of administration –Generally given IV but may be given IM or PO in some cases –For IV medication, the patient should leave the hospital with a saline lock in place if possible ANTIPSYCHOTICS
  • 76. • Considerations… – Discuss all medication issues with the sending physician before leaving the hospital – If the patient is sedated upon your arrival, ask if the drug will last long enough for you to reach your destination • Transfers of more than 2 hours are not uncommon ANTIPSYCHOTICS
  • 77. • Considerations… –If medication will be needed during transport, do not wait until the patient becomes disruptive and combative –Make sure that any patient who is medicated or may require medication during transport is “Blue papered” ANTIPSYCHOTICS
  • 78. • What to watch for during transport: –Respiratory depression –Hypotension –Seizures –Extrapyramidal reactions • Agitation, muscle tremor, drooling, tremors, etc. ANTIPSYCHOTICS
  • 79. • Potential interventions in cases of adverse or allergic reactions: – Treat allergic reactions and seizures as per Maine EMS protocols – Support ventilations as necessary and be prepared to intubate – Consider fluids for hypotension – Diphenhydramine for extrapyramidal reactions – OLMC for other options including diversion ANTIPSYCHOTICS
  • 80. CARDIAC GLYCOSIDES • These are essentially digitalis preparations –The most commonly used drug is digoxin (Lanoxin) –Generally used to treat atrial fibrillation, atrial flutter or atrial tachycardias –Sometimes used to treat CHF
  • 81. Route of Administration: • Generally IV infusion CARDIAC GLYCOSIDES
  • 82. • What to watch for during transport: –Dysrhythmias including heart blocks –Cardiac arrest –Nausea/vomiting –Digitalis toxicity CARDIAC GLYCOSIDES
  • 83. • Potential interventions for adverse reactions: –Treat all dysrhythmias per Maine EMS protocols –Consider promethazine for nausea/vomiting –Contact OLMC for options of discontinuing drug, altering dose or diversion CARDIAC GLYCOSIDES
  • 84. • All patients on cardiac glycosides must be transported on a cardiac monitor and watched carefully for developing adverse reactions CARDIAC GLYCOSIDES
  • 85. CORTICOSTEROIDS • Medications in this class are primarily used to treat the following: – Cerebral edema associated with head injury – Status asthmaticus – To suppress the immune system in cases of severe allergic reactions/anaphylactic shock – Chronic inflammatory conditions
  • 86. • Routes of administration: –IV infusion in most cases –Also used in inhaled form for certain respiratory conditions CORTICOSTEROIDS
  • 87. • Commonly used medications in this class –Betamethasone (Celestone) –Dexamethasone (Decadron) –Methylprednisolone (Solu-Medrol) –Hydrocortisone (Solu-Cortef) CORTICOSTEROIDS
  • 88. • Also in inhaled form… –Beclomethasone (Beconase, Beclovent) –Triamcinolone (Azmacort, Kenalog) –Flunisolide (Aerobid) CORTICOSTEROIDS
  • 89. • What to watch for during transport: –Hypertension –Nausea/vomiting –CHF CORTICOSTEROIDS
  • 90. • Potential interventions in case of adverse reactions: –Follow Maine EMS protocols for allergic reactions, CHF or nausea/vomiting –Contact OLMC for options of discontinuing drug CORTICOSTEROIDS
  • 91. DROTRECOGIN • An antisepsis agent • Used to treat severe sepsis or septic shock • Administered by IV infusion only
  • 92. • What to watch for during transport: –Be alert for signs of internal bleeding –Shock symptoms DROTRECOGIN
  • 93. • Potential interventions during transport : –Treat for shock –Contact OLMC for option of discontinuing drug DROTRECOGIN
  • 94. GASTROINTESTINAL AGENTS • Used to treat a variety of GI disorders • Several different sub- classifications of GI medications: 1. Proton Pump Inhibitors 2. Somatostatin Analogues 3. H2 Blockers 4. Anti-emetics
  • 95. • Commonly used drugs: –Protonix –Prevacid Protein Pump Inhibitors
  • 96. • Commonly used drug: –Sandostatin Somatostatin Analogues
  • 97. • Commonly used drug: –Famotidine (Pepcid) –Cometidine (Tagamet) H2 Blockers
  • 98. Anti-emetics • metoclopramide (Reglan) • ondansetron (Zofran) • prochlorperazine (Compazine)
  • 99. • What kind of patients will we see being transported on these medications? –Active duodenal or gastric ulcers –GERD—gastric esophageal reflux disease –Upper GI bleed –Esophageal varices GASTROINTESTINAL AGENTS
  • 100. • Routes of Administration: –IV infusion –PO GASTROINTESTINAL AGENTS
  • 101. • What to watch for during transport: –Adverse reactions are rare but may consist of dysrhythmias –Hypoglycemia is possible but will probably only be seen on longer transfers GASTROINTESTINAL AGENTS
  • 102. • Potential interventions for adverse or allergic reactions: –Treat dysrhythmias and hypoglycemia per Maine EMS protocols –Consider termination of drug –OLMC for further options GASTROINTESTINAL AGENTS
  • 103. IV FLUIDS • Consists of a wide variety of fluids including the following: –Normal saline, ½ NS –Lactated Ringers –D5W and D10W –Dextran, Plasmanate –Hetastarch, albumin
  • 104. • Why do we give IV fluids during transport? –Increase or maintain blood volume and blood pressure –Maintain hydration –Access for medication –Treat hypoglycemia (D10W) IV FLUIDS
  • 105. • What to watch for during transport: –Signs of fluid overload –Edema –Pulmonary edema –Take vitals often to monitor BP IV FLUIDS
  • 106. • Potential interventions in cases of adverse reactions: –Consider discontinuing or reducing rate of infusion –Treat CHF per Maine EMS protocols IV FLUIDS
  • 107. ELECTROLYTES • Electrolytes consist of the following: –Potassium –Calcium –Sodium chloride –Sodium bicarbonate (alkalizing agent)
  • 108. • What type of patients will we see who require electrolyte therapy? –Patients requiring potassium supplementation due to deficiency diseases when oral replacement is not feasible –Those who have lost potassium due to severe vomiting or diarrhea ELECTROLYTES
  • 109. • What type of patients will we see who require electrolyte therapy? –Patients with severe hypocalcemia –Sodium depletion –Patients requiring sodium bicarbonate to treat hyperacidity or metabolic acidosis due to shock or dehydration ELECTROLYTES
  • 110. • Route of administration: –Primarily IV infusion ELECTROLYTES
  • 111. • What to watch for during transport: –Dysrhythmias –Seizures –Signs and symptoms of allergic reactions (rare) ELECTROLYTES
  • 112. • Potential interventions in cases of adverse reactions: –Treat seizures and dysrhythmias per Maine EMS protocols –Consider option of discontinuing drug or modifying dose as per OLMC or transfer orders ELECTROLYTES
  • 113. NARCOTICS • Used to control moderate to severe pain • May be administered by IV infusion pump but may also be given by IV or IM injection as per transfer order
  • 114. • Commonly used narcotics: –Fentanyl –Morphine –Hydromorphone (Dilaudid) –Meperidine (Demerol) –Pentazocine (Talwin) NARCOTICS
  • 115. • What to watch for during transport: –Respiratory depression –Hypotension –Nausea/vomiting –Bradycardia NARCOTICS
  • 116. • Potential interventions in cases of adverse reactions: –Consider discontinuing medication –Treat dysrhythmias per Maine EMS protocols –Consider Naloxone –Assist ventilations as necessary and be prepared to intubate NARCOTICS
  • 117. PARENTERAL NUTRITION • Used to treat the following: –Patients requiring nutrition who are unable to take food and/or fluids by mouth –Patients requiring vitamin supplements to prevent or treat vitamin deficiency conditions
  • 118. • Common forms include the following: –Vitamin solutions –TPN (Total Parenteral Nutrition) • An individualized solution designed to meet the needs of the patient PARENTERAL NUTRITION
  • 119. • What to watch for during transport: –Adverse or allergic reactions are rare but have been seen –Hypoglycemia • Can occur since most TPN preparations contain Insulin PARENTERAL NUTRITION
  • 120. • Potential interventions in case of adverse reactions: –Treat hypoglycemia as per Maine EMS protocols –Consider discontinuing drug PARENTERAL NUTRITION
  • 121. GLYCOPROTEIN IIb/IIa Platelet Inhibitors • What are these drugs all about? –They are potent agents that inhibit platelets from aggregating or clumping together in the context of coronary artery disease. –Frequently used in combination with Heparin
  • 122. • Patients being transported on these drugs – Acute MI – Unstable angina – Acute coronary syndrome – Many of these patients are being transported to the cath lab for diagnostic and/or interventional catherization---angioplasty GLYCOPROTEIN IIb/IIa Platelet Inhibitors
  • 123. • Route of Administration: –IV infusion only GLYCOPROTEIN IIb/IIa Platelet Inhibitors
  • 124. • What to watch for during transport: –Any signs of bleeding –Signs and symptoms of shock –Changes in level of consciousness GLYCOPROTEIN IIb/IIa Platelet Inhibitors
  • 125. • Potential interventions in cases of adverse or allergic reactions: – Control any external bleeding – Treat for shock as needed – Contact OLMC for options of discontinuing drug, altering dose or diversion – In cases of suspected bleeding, the provider may also have to D/C heparin if it is also being administered – Treat dysrhythmias and allergic reactions as per Maine EMS protocols GLYCOPROTEIN IIb/IIa Platelet Inhibitors
  • 126. MULTIPLE MEDICATIONS • Keep in mind that you will often be transporting patients on 2, 3 or even more medications – Eg.: It is common to transport a cardiac patient on nitroglycerin, Heparin and Aggrastat with an order to administer Fentanyl for pain as needed.
  • 127.
  • 128. SCENARIO 2 • We have discussed the option of diversion to a nearby hospital in almost each of the classifications that we have examined • This is often a difficult decision to make for a number of reasons • What are the potential benefits of diversion?
  • 129. • What are the potential negative aspects of diversion? • What factors should be considered in deciding to divert? • Can you divert without authorization from OLMC? SCENARIO 2
  • 130. • DIVERSION CONSIDERATIONS –Patient condition –Transfer orders –Ability to treat –Distance to receiving or sending facility –Consult with OLMC –Comfort level of paramedic SCENARIO 2
  • 131. RESPIRATORY MEDICATIONS • Within this classification are several subclassifications of drugs that are used in treating patients with respiratory conditions – Beta agonists – Anticholinergics – Steroids – Mucolytics – Miscellaneous
  • 132. • Albuterol (Proventil) • Terbutaline • Metaproterenol (Alupent) • Piruterol (Maxair) BETA AGONISTS These drugs provide relief through bronchodilation
  • 133. ANTICHOLINERGICS • Ipratropium (Atrovent) These drugs provide long term maintenance of bronchodilation
  • 134. STEROIDS • Beclomethasone (Beclovent) • Flunisolide (AeroBid) • Fluticasone (Flovent) • Triamcinolone (Azmacort) These drugs provide relief by reducing inflammation
  • 136. • What kinds of patients will you be transporting on respiratory medications? – The respiratory problem may be primary or secondary – Acute or chronic RESPIRATORY MEDICATIONS
  • 137. • Asthma • COPD • Emphysema • Certain cases of allergic reaction RESPIRATORY MEDICATIONS
  • 138. • Routes of administration: –Most of these drugs will be administered by inhaler or nebulized • Aminophylline is given by IV infusion • Terbutaline may be IV or by inhalation • Is epinephrine a respiratory medication? RESPIRATORY MEDICATIONS
  • 139. • Transport respiratory medication patients on cardiac monitor RESPIRATORY MEDICATIONS
  • 140. • What to watch for during transport: –Dysrhythmias • Beta agonists such as Albuterol can cause tachydysrhythmias –Palpitations, chest pain RESPIRATORY MEDICATIONS
  • 141. • Potential interventions in case of adverse reaction: –Treat dysrhythmias and chest pain per Maine EMS protocols RESPIRATORY MEDICATIONS
  • 142. SEDATIVES • Sedatives consist of a variety of medications from several different classifications (Some that we have already reviewed) – Narcotics – Benzodiazepines – Antipsychotics – Barbiturates and anesthetics
  • 143. • Narcotics – Fentanyl, morphine, dilaudid, meperidine, etc. • Benzodiazepines – Diazepam, lorazepam, midazolam • Antipsychotics – Haloperidol, risperidone, chlorpromazine, etc. • Barbiturates – Phenobarbital, thiopental, amobarbital • Anesthetics – Etomidate, propofol SEDATIVES
  • 144. • NOTE: Paramedics will not transport patients on anesthetics unless accompanied by an RN –Most patients on anesthetics are intubated SEDATIVES
  • 145. • Types of patients on sedatives… –Agitation and combativeness associated with head injury, psychosis, etc. –Control of seizure activity –Any condition where it is necessary to provide sedation SEDATIVES
  • 146. • What to watch for during transport: –Respiratory depression –Hypotension –Bradycardia SEDATIVES
  • 147. • Potential interventions in cases of adverse reactions: –Oxygen, Support ventilations as necessary and be prepared to intubate –Treat bradycardia per Maine EMS protocols –Consider fluids for hypotension –OLMC for other options SEDATIVES
  • 148. • Take vitals often • Transport on cardiac monitor SEDATIVES
  • 149. VASOACTIVE AGENTS • These are medications that have an effect on the tone and caliber or diameter of blood vessels – Vasopressors and sympathomimetic drugs cause constriction of blood vessels……. – Nitrates, vasodilators, Calcium Channel Blockers and ACE Inhibitors cause relaxation and dilation of vessels, thereby reducing BP
  • 150. • What kinds of patients will we see on Vasopressors and Sympathomimetics? –Patients on these drugs are generally being treated for hypotension and certain types of shock VASOACTIVE AGENTS
  • 151. • Commonly used vasopressors and sympathomimetics: –Vasopressin (Pitressin) –Metaraminol (Aramine) –Dopamine (Intropin) –Dobutamine (Dobutrex) –Epinephrine and norepinephrine –Isoproterenol (Isuprel) VASOACTIVE AGENTS
  • 152. • Patients taking nitrates are generally being treated for ischemic chest pain or hypertensive crisis NITRATES
  • 153. NITRATES • Commonly used nitrates include: –Nitroglycerin –Nitroprusside (Nipride)
  • 154. VASODILATORS • Used primarily for treatment of hypertensive crisis and management of CHF
  • 155. • Calcium Channel Blockers and ACE Inhibitors are primarily used to treat hypertension as we saw in the section on Antihypertensives VASOACTIVE AGENTS
  • 156. • Routes of administration: –IV infusion • Usually by infusion pump VASOACTIVE AGENTS
  • 157. • What to watch for during transport: –Severe hypotension or hypertension –Dysrhythmias –Dyspnea –Altered level of consciousness –Nausea/vomiting VASOACTIVE AGENTS
  • 158. • Potential interventions in case of adverse or allergic reactions: – Treat dysrhythmias as per Maine EMS protocols – Consider fluids for hypotension – Consider discontinuing drug or modifying dose as per OLMC or transfer order – Diversion VASOACTIVE AGENTS
  • 159. • NOTE: –These patients must be transported on a cardiac monitor –Monitor vitals frequently VASOACTIVE AGENTS
  • 160. OTC MEDICATIONS • During the course of a transport, particularly a long distance transfer, it may be necessary to administer certain commonly used OTC medications
  • 161. • May include medications for the following: • Pain (Ibuprofen, acetaminophen, etc.) • Motion sickness (Dramamine) • Antacids • Antihistamines OTC MEDICATIONS
  • 162. • Guidelines for administration: –Written order by physician that includes name of drug, route of administration, indication, dose and time of initial and repeat dosing –Drug must be supplied by the sending facility –Drug must have been used previously by patient without adverse reactions OTC MEDICATIONS
  • 163. • Administration must be documented as with all other medications • Remember that even OTC drugs can result in adverse or allergic reactions so watch for any such reactions following administration OTC MEDICATIONS
  • 164. PRESCRIPTION DRUGS • During longer transports you may need to administer one or more of the patient’s regular prescription drugs • The drug must be included in one of the classifications that are part of the PIFT module
  • 165. CONCLUSIONS • Be constantly alert—patients can change in seconds • Know your drugs---use resources • Remember that every drug, even OTC drugs, have the potential to result in a serious adverse reaction
  • 166. CONCLUSIONS • Never leave the sending facility unless you feel thoroughly comfortable with your patient and with the medications you are being asked to administer or monitor
  • 167. • Make sure that you are thoroughly prepared for any complication • Know where possible diversion hospitals are located • Use OLMC whenever necessary CONCLUSIONS