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Nimesulide composition
1. Nimesulide composition
Nimesulide is a Non steroidal anti inflammatory drug (NSAID) and targets COX-
2 an enzyme responsible for inflammation & pain.
The nimesulide is preferably used in the composition in an amount of 0.1-5%
by weight, more preferably in an amount of 0.1-3% by weight, most preferably
in an amount of around 1 % by weight of the composition.
This medication is for the most part used as an issue of the treatment of
inflammatory torment and also used for postoperative trauma, sports injuries,
acute musculoskeletal disorders.
Nimesulide have pain relieving and antipyretic properties which, specially
restrains the protein cyclooxygenase-2 (COX-2) and has better gastro-
intestinal bearableness in addition to different Nsaids in its class.
Nimesulide is indicated in the treatment of a variety of painful inflammatory
conditions including those associated with osteoarthritis, postoperative
trauma, sports injuries, acute musculoskeletal disorders including tendonitis,
tenosynovitis, sprains, strains and low back pain, ear, nose and throat
disorders, dental surgery, bursitis/tendonitis, thrombophlebitis, pharyngitis
and gynaecological disorders.