It is available in a variety of forms: tablets, powder for dissolution in water, suppositories, mouth dissolving tablets and topical gel.

1. Nimesulide dosage
An NSAID agent- Nimesulide is widely used in the treatment of variety of painful inflammatory
conditions including those associated with osteoarthritis, postoperative trauma, sports injuries, acute
musculoskeletal disorders.
Nimesulide is been available since 1985 with a multifactorial mode of action.
Nimesulide is indicated for the treatment of acute pain, Painful osteoarthritis (Swelling in the joints) and
primary dysmenorrhoea. It is considered as the most prescribed tablet for various pain relief
The maximum duration and dose of a treatment course with nimesulide is recommended with the
shortest period of 15 days, 100 mg twice a day, to minimize the risk of hepatotoxicity.
Nimesulide should only be prescribed as second line treatment. The decision to prescribe nimesulide
should be based on assessment of the individual patient.
Nimesulide has superior gastrointestinal safety as compared to other NSAIDs. Its multifactorial mode of
action gives it a unique and broad action on inflammatory processes.
Nimesulide also improves the skin tone and to increase in energy levels. Food, gender and advanced
age have negligible effects on Nimesulide pharmacokinetics.
The approved dosage of Nimesulide should be 100mg twice daily and the duration of the
treatment should not exceed 15days to minimize the risk of hepatotoxicity.