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Nimesulide tablet synthesis
1. Nimesulide tablet synthesis
Nimesulide, a COX-2 selective drug, possesses anti-inflammatory and analgesic
properties. Moreover, it has low gastro-intestinal and renal toxicity.
Its main purpose is to treat acute pain, the symptomatic treatment of osteoarthritis and
primary dysmenorrhoea .
As for other NSAIDs the use of Nimesulide is preffered for the shortest duration necessary
to control symptoms in patients with acute pain or primary dysmenorrhoea.
The efficacy of Nimesulide was consistently superior to placebo with its particularly rapid
onset action.
The maximum duration and dose of a treatment course with nimesulide is 15 days, 100 mg
twice a day, to minimize the risk of hepatotoxicity.
Nimesulide Tablet shows the result from pain within 15min from the drug intake