Zigbir is a synergistic blend of phytochemical actives possess all characteristics of ideal growth promoter which have proved number of times, since last decade.

1. Z i gb
ir
Zigbir
Complete Performance Enhancer
Global trend
Nowadays, Natural Growth Enhancers (NGEs) are
commonly included in feed and water for poultry to
prevent gut infections and enhance overall performances
with reducing the medication costs. NGEs are promoted
as potential substitutes to antibiotics, which are used for
growth promotion.
The use of antibiotics due to their residues in food and
Benefits of natural the resistance of some pathogens (ie, Salmonella,
performance enhancer Campylobacter, E.Coli, among others) in animals and
humans, turned into a topic of immense interest in the
Balances gut bacterial flora recent years. Antibiotic was a great discovery for animal
production in the 1940'/1950's, in the late 1990's in Europe,
Reduces the nutrients available for
the pressure to remove antibiotic growth promoters
pathogens
(AGPs) was gradually increasing. AGPs have even been
Improves growth performances banned by the European Union since 2006 in feed and also
and feed efficiency by an important fast food chain in USA. Unfortunately, in
Improves food safety animal production and especially in poultry, the misuse
and the overuse of antibiotics have lead to the emergence
Enhances animal welfare by of bacteria resistances in animals.
decreasing all kinds of stress The restriction on the use of AGPs resulted in a
negative impact on poultry performance. Undigested
feed is a potential substrate for microbial fermentation.
Ideal performance The use of poorly digested ingredients runs the risk not
enhancer only of poor performance, but there is an additional
danger from microbial overgrowth and subsequent
Should be effective & economical disease/intestinal disorders. So, NGEs became a pragmatic
for regular use option to substitute antibiotic use for enhancing growth.
Should not be absorbed from the
gut into edible tissue (residual
effect) Z
Should not be involved with I
transferable drug resistance/cross- G
resistance
B
Should be readily bio-degradable
and nontoxic to birds and human
I Counteracts ill effects of chemical toxins
handlers (J.Walter,1980) R

2. “Andrographolide”
The wonder phytochemical in Zigbir
Improves bile flow
Treatment Dose Bile Flow Rate
Better bile flow supports optimum utilization of fat, Groups (mg/kg) (Mean+SE)*
thereby optimum weight gain, feed conversion,
utilization of fat soluble vitamins & pigment Control – 21.83 + 1.27
(xanthophyll).
Andrographolide
Better Choleretic effect treatment 80 35.49 + 1.51
Andrographolide extends better Choleretic effect
*Bile flow was measured as mg/5min/100g body weight
compared to Silymacin with respect to bile flow, bile (Ref: G.S.Tripathi & Y.B.Tripathi - Phytotherapy Research, Vol. 5, 176-178 (1991))
salts, cholic acids and deoxycholic acid. (Shukla et al
1992, Planta medica, 58,146 – 149) Treatment Dose Sleeping time
Better liver metabolism Groups (mg/kg) (Mean+SE)
Andrographolide treatment significantly reduces Control – 76.33 + 2.25
sleeping time (induced by Pentobarbitone sodium),
indicates enhancement in process of liver metabolism. Andrographolide
treatment 80 31.00 + 2.29
(Ref: G.S.Tripathi & Y.B.Tripathi - Phytotherapy Research, Vol. 5, 176-178 (1991))
Major constituent in Zigbir
Andrographis paniculata Active Principle: Andrographolide
is readily bio-degradable
is safe to birds and human handlers
Zigbir is not involved in drug resistance
mixes well with feed
is thermally stable
enhances the performance effectively &
economically

3. Improves gut metabolism: Activates intestinal S-Transferase, DT-diaphorase & Superoxidase
brush border membrane-bound hydrolases viz. dismutase indicate improvement in process of
lactase, maltase and sucrase in all three regions of hepatic detoxification. (Singh et al, (2001)
small intestine (viz. duodenum, jejunum and Phytoether. Res. 15, 382-390)
ileum). Usage
Oral administration of Andrographis paniculata To optimize body weight gain, FCR & livability
®
accelerates intestinal digestion & absorption of in commercial broilers. While, uniform sexual
c a r b o h y d r a t e s b y a c t i va t i n g i n t e s t i n a l maturity, optimum egg production, FCR,
disaccharideses. (Ref: Choudhary BR, Poddar livability and shell thickness in commercial
MK; Methods Find Exp Clin Pharmacol, 1985 Dec; 7 layers and breeders.
(12): 617-21)
To optimize hepatic functions including
®
Improves xanthophyll pigmentation: Premium detoxification.
prices are received for eggs of guaranteed high
Mixing Rate: 300 to 400 gms per ton of feed.
NEPA number (National Egg & Poultry
Please ensure thorough mixing.
Association standard for pigmentation). Many
consumers still associate yellow shank and skin During high risk period: Depending on the
colour of broilers with healthy chicken. (Source : quality of feed ingredients and atmospheric moisture
Scott et.al., 1982) content, the mixing rate may be altered up to 400 g
per ton of feed or as suggested by nutritionist.
Improvement hepatic detoxification: Significant
increase in levels of Acid soluble sulphydryl (-SH) Recommendation
content, Cytochrome P450, Cytochrome P450 Broilers and Layers : From day one continuously,
reductase, Cytochrome b5 reductase, Glutathione till marketing.
10 kg multilayer bag
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