The document discusses various aspects of aging, including its association with cellular energy decline, organ dysfunction, and inflammation. It details the LifeWave Aeon approach, which aims to reduce stress and inflammation, thus potentially improving overall health and longevity through specific biochemical mechanisms. Clinical evidence indicates that regular use of Aeon can enhance energy levels, organ function, and skin quality while addressing inflammation-related issues.

1. A New Era in Anti-Aging

2. Facts About Aging: Aging is associated with the decrease in cellular energy Aging is associated with a decline in organ function Aging is associated with a state of dehydration Aging is associated with the depletion of vital nutrients

3. Age - Related Symptom Solution Decrease in cellular energy Energy Enhancer Decline in organ function Multiple Patches Tissue damage Glutathione/ Carnosine State of dehydration Energy Enhancer/ Water Decline in hormones level Supplementation / Bioindenticals Stress on body Aeon Genetic damage/ loss of info To be determine

4. The Lifewave Approach To Date : Energy Enhancer increases cellular energy from fat burning Silent Nights improves the quality of sleep which promotes better tissue repair Carnosine promotes restoration of cells to youthful levels and retention of body mass Glutathione protects our body from damage Research shows that regular stimulation of ST36 may lengthen telomeres extending life span How does Aeon improve on this system and improve on this powerful anti aging effects ? What benefits can you expect from Aeon ?

5. How did this new development come about ?: Cutting - edge doctors are looking at the factors that causes cancer and aging and specifically how aging and toxins can cause stress, inflammation and damage to our DNA David Schmidt and Dr Steve believe that it is possible to reverse this stress, inflammation and genetic damage Best of all this is possible with Lifewave technology

6. How did this new development come about ?: For more then 50 years physiologist have known that putting stress on an animal causes it to age very quickly. When you place a mouse on an electric grid and administer shocks …. you arouse the mouse’s stress response. After a few days of such stress the mouse will die, and on autopsy its tissue will display many signs of accelerated aging. Deepak Chopra, Ageless Body, Timeless Mind

7. Facts About Aging : What is so striking about long term consequences of stress is that taken all together it looks like growing old. Hypertensions, ulcers, impotence, wasted muscles, and diabetes are all common signs of aging. On the surface all these appear to be unrelated symptoms but they become unified as extreme results of the stress response . Deepak Chopra – Ageless Body, Timeless Mind

8. Stress and its connection to aging : Stress is a term that refers to a failure in an organism – human or animal – to respond appropriately to emotional or physical threats, whether actual or imagine. Stress symptoms normally include adrenaline production exhaustion, irritability and muscular tension, inability to concentrate, headache and elevated heart rate

9. Chronic stress can effectively effect the body’s immune system Immune sytem changes can create more vulnerability to infection and have been observe to increase the potential for an outbreak in Psoriasis for people with that skin disorder

10. Aging & Inflammation (source – Life Extension magazine) : Systemic inflammation can cause degenerative effects Inflammation is caused by an increase in destructive chemicals A clear sign of aging is elevated levels of inflammation Chronic inflammation is also found in atherosclerosis cancer, obesity, diabetes, congestive heart failure, digestive disorder, Alzheimer's disease and others,

11. Conclusion: Many seemingly unrelated disorders have a common link: Inflammation . Most importantly inflammation can damage DNA resulting in shortened life span

12. New Surgical Horizons: Chronic inflammation and oxidative stress in the genesis and perpetuations of cancer: role of lipid peroxidation, DNA damage, and repair Helmut Bartsch & Jagadeesan Nair, published 15 th Aug 2006 # Springer-Verlag 2006. Conclusion: Persistent oxidative stress are induced by inflammatory processes in a self perpetuating process and cause progressive accumulation of DNA damage in target organs. Together with deregulation of cell homeostasis, the resulting genetic changes act as driving force in chronic inflammation associated human disease pathogenesis

13. “ Everyone assume we age by rust. But how do you explain animals that don’ t age?. Some tortoise may lay eggs at age 100 years, there are whales that live to be 200 and clams that make it past 400 years” Stuart Kim,PHD, Stanford University Professor of Development Biology and Genetics (May, 2010) A prevailing theory of aging has been challenged by Stanford University Medical School researchers. Their discovery contradicts the theory that aging is a build up of tissue damage similar to rust. The Stanford findings suggest specific genetic instructions drive the process. If they are right, science might one day find ways of switching the signals off and halting or even reversing aging

14. The Basic Premise of Lifewave Aeon: Develop a signaling mechanism to reduce stress on the human body Develop a signaling mechanism to reduce inflammation Develop a signaling mechanism to protect and restore our DNA to a youthful state

15. Simple explanation: Lifewave Aeon elevates multiple “anti-stress factors” and decreases inflammation So the Lifewave Aeon patch is not a single mechanism. Instead, multiple “anti-stress” pathways are targeted to reduce stress and inflammation, thereby increasing life span through multiple pathways

16. Phenylacetylglutamine (PG) : Lifewave research also shows a connection between and altered levels of a polypeptide called Phenylacetylgutamime (PG) PG could turn up to be the most important anti aging polypeptide in the human body

17. At conception, most genes in our body are active. In our youth we have the optimum balance between active and inactive genes, but as we age more and more of our genes (genetic information) becomes silenced (methylated) When the gene is no longer needed it is “methylated” To make it inactive (loss of genetic information).

18. Here is the problem with this: When we have a balance in gene expression, we are in a youthful healthy state. When we age and this gene expression changes we will lose genetic information : … . That supports detoxification pathways … . That regulates cholesterol metabolism … . That regulates inflammation … . That regulates cell life/ death cycle … . And many undesirable side effects

19. Clinical testing by Lifewave has demonstrated the following : A unique biochemistry with a chain of beneficial effects: Dr Clark – rapid reduction in inflammation Dr Greenberg – improved cellular repair & organ function Dr Budzynski – normalization of the nervous system; a key to anti-aging and stress reduction Dr Haltiwanger -

20. Clinical testing by Lifewave has demonstrated the following : Aeon reduces stress as measured by increase activity of the parasympathetic nervous system By reducing tissue and organ damage we can reduce the wear and tear associated with aging - NOW Aeon reduces the biochemical markers of inflammation that cause tissue and organ damage

21. Future Clinical Testing to follow : We will test to see if Lifewave Aeon has a direct effect on DNA; specifically biochemical mechanism that repairs genetic damage, increasing life span Dramatic synergistic effects between regular use of Lifewave Aeon and other Lifewave patches

22. What will Lifewave Aeon mean to you TODAY ? : Improved Energy Reduction in pain and inflammation Improved in skin quality and appearance Reduction in stress and inflammation Improvement in organ function Improvement in the way you handle stress The patch compliments all the other Lifewave patches

23. The patch compliments all the other Lifewave patches Have low energy? Use Energy Enhancer and Aeon Have pain ? Use Icewave and Aeon Have poor skin ? Use the Y-Age System Trouble Sleeping ? Use Silent Nights and Aeon Appetite Control ? Use SP6 Complete and Aeon

24. Aging Stress Oxidative Inflammation Cell & Organ Damage

25. Aeon Patch Points

26. aeon (ē ‘ ŏn., ē ‘ an). noun An immeasurable or infinite space of time; eternity, a long space of time; an age.* A Revolutionary New Anti-Aging Product From Lifewave

27. Biochemical Markers of Inflammation Increased C-Reactive Protein Increased in Fibrinogen Increase in Homocysteine Increase in Lipid Peroxides Increased Cytokine production with an imbalance inflammatory Cytokines

28. Parasympathetic activity curbs sympathetic activity DHEA reduces oxidative stress and increase anti-inflammatory signals Inflammatory Cytokines Anti-Inflammatory Cytokines Oxidative Stress Parasympathetic Sympathetic Cortisol DHEA

29. Fibrinogen, a protein made by the liver, may rise sharply in any condition that cause inflammation or tissue damage A high fibrinogen level is significantly associated with coronary artery disease, carotid atherosclerosis and strokes. (De Luca et al, 2010, Kwaan, 2010) These conditions cause 60% of the death in the elderly

30. High fibrinogen can cause a heart attack or stroke via several mechanisms, including increased blood clots and excessive blood thickening The new England Journal of Medicine studies showed that those with high levels of fibrinogen were more then twice to die of a heart attack. Lef.org

31. Elevated C-reactive protein (CRP) is a biochemical marker of underlying chronic inflammation (Vasovic et al., 2010) C-reactive protein is often sharply elevated in aged people with multiple degenerative diseases Systemic chronic inflammation plays a central role in age-related diseases

32. “ People with high levels of CRP, one of the cardinal markers of inflammation , were over 4 times more likely to have heart attacks then those with low levels of CRP (Sinatra, 2004) Aeon testing showed a trend of lower CPR levels

33. Varying degrees of high levels of homocysteine are detectable in all inflammatory diseases and it is a marker for inflammation (Wu, 2007) Via Oxidative Stress High Homocysteine Acute & Chronic Inflammation

34. Organs most affected by chronic inflammation: Brain Heart Kidneys Lungs Arteries Homocysteine – induced oxidative stress: Damages blood vessels Favors lipid peroxidation and Induces production of inflammatory factors (Lin et al 2009)

35. Why are lipid peroxides important ? The level of lipid peroxides is a measure of cellular membrane damage caused by the action of free radicals (Miquel et al., 1998) The elevation of lipid peroxides is an early warning of the potential of oxidative stress The outcome of long term oxidative stress is chronic degenerative disease ( Halliwell et al., 1998)

36. Damage to the structure of cell membrane molecules lead to changes in their: Permeability Transport mechanism Communication signalling This disrupts many cellular processes

37. Reduction of inflammation by Aeon Decreased C-Reactive protein levels Decreased Fibrinogen levels Decreased Homocysteine levels Decreased Lipid Peroxide levels