Keynote paper at the 2016 Alzheimers NZ Biennial Conference and 19th Asia Pacific Regional Conference of Alzheimer’s Disease International, Wellington, New Zealand, November 2016
This document discusses the economic burden of diabetes in India. It notes that diabetes leads to a 17 times higher risk of blindness, over 50% of dialysis patients and amputations are due to diabetes, and diabetes is associated with a 4 times higher risk of hypertension. The costs of managing diabetes are high due to factors like delayed diagnosis, complications from the disease, and costs of drugs, hospitalizations, and surgeries. The costs are expected to rise significantly in the future. Currently, about two-thirds of healthcare spending in India is out-of-pocket. The document discusses the need for health insurance and social health insurance models to help address the rising economic burden of diabetes.
The document provides an agenda and background information for a stakeholder scoping workshop on long term conditions. The workshop aims to define the scope of a joint strategic needs assessment on long term conditions by gaining consensus on key conditions and cross-cutting themes to focus on. Presentations will cover the changing landscape of long term conditions, definitions and prevalence locally, and identifying priority conditions and common issues. Breakout groups will discuss potential conditions and themes to prioritize. Understanding local data availability and stakeholder priorities will help shape the needs assessment.
As the burden of NCDs increases, various countries have introduced new and innovative modes of managing them in primary healthcare setting. APO, in conjunction with Duke Kunshan University, China, conducted a 4-country study (Bangladesh, China, Nepal and Viet Nam) to understand the different approaches used in involving CHWs in preventing and managing NCDs. Access full publication here http://bit.ly/2XnWwcd
This document summarizes Thailand's response to the COVID-19 pandemic between September 2020 and November 2020. It covers preventing local transmission through measures like health communication, physical distancing, and testing. It also discusses ensuring infrastructure and workforce capacity, providing health services, financing coverage, governance, and multi-sectoral measures. The November 2020 update focuses on gradually lifting restrictions while maintaining preparedness for a potential second wave through ongoing surveillance, prevention, and rapid response systems.
This review outlines the main organizational, financing, human resources and service delivery features of the health-care system. Although there has been implement in overall health outcomes since the 1990’s the current levels are still below average for the country’s Pacific neighbors. The remoteness of the many rural communities has hampered improvements in health services. This is one of the major challenges that the country faces in order to achieve SDG heath targets by 2030. This Hits highlights steps taken to overcome challenges especially in the face of epidemiological change in disease burden that is slowly taking place in the country.
World Psychiatric Association - Health Systems' Performance Roundtable cana...Université de Montréal
This was part of a roundtable presentation on health systems' performance around the world, focusing on psychiatric care. My contribution was a survey of the Canadian health care system's performance.
This document discusses improving health information systems for monitoring non-communicable diseases in the Pacific region. It outlines the importance of health information systems and cause-specific mortality data for policymaking and evaluating disease prevention programs. Current issues with mortality data quality in many Pacific countries are described, where many deaths occur outside of health institutions and cause of death is often misclassified. Efforts underway to improve data quality include training doctors in cause of death certification and developing national strategies to strengthen civil registration and vital statistics systems.
Risk profiling, multiple long term conditions & complex patients, integrated ...Dr Bruce Pollington
Dr Bruce Pollington web-ex presentation to LTC QIPP programme
Utilising risk profiling, and risk stratification to identify patients with multiple long term conditions requiring complex care through integrated care teams.
This document discusses the economic burden of diabetes in India. It notes that diabetes leads to a 17 times higher risk of blindness, over 50% of dialysis patients and amputations are due to diabetes, and diabetes is associated with a 4 times higher risk of hypertension. The costs of managing diabetes are high due to factors like delayed diagnosis, complications from the disease, and costs of drugs, hospitalizations, and surgeries. The costs are expected to rise significantly in the future. Currently, about two-thirds of healthcare spending in India is out-of-pocket. The document discusses the need for health insurance and social health insurance models to help address the rising economic burden of diabetes.
The document provides an agenda and background information for a stakeholder scoping workshop on long term conditions. The workshop aims to define the scope of a joint strategic needs assessment on long term conditions by gaining consensus on key conditions and cross-cutting themes to focus on. Presentations will cover the changing landscape of long term conditions, definitions and prevalence locally, and identifying priority conditions and common issues. Breakout groups will discuss potential conditions and themes to prioritize. Understanding local data availability and stakeholder priorities will help shape the needs assessment.
As the burden of NCDs increases, various countries have introduced new and innovative modes of managing them in primary healthcare setting. APO, in conjunction with Duke Kunshan University, China, conducted a 4-country study (Bangladesh, China, Nepal and Viet Nam) to understand the different approaches used in involving CHWs in preventing and managing NCDs. Access full publication here http://bit.ly/2XnWwcd
This document summarizes Thailand's response to the COVID-19 pandemic between September 2020 and November 2020. It covers preventing local transmission through measures like health communication, physical distancing, and testing. It also discusses ensuring infrastructure and workforce capacity, providing health services, financing coverage, governance, and multi-sectoral measures. The November 2020 update focuses on gradually lifting restrictions while maintaining preparedness for a potential second wave through ongoing surveillance, prevention, and rapid response systems.
This review outlines the main organizational, financing, human resources and service delivery features of the health-care system. Although there has been implement in overall health outcomes since the 1990’s the current levels are still below average for the country’s Pacific neighbors. The remoteness of the many rural communities has hampered improvements in health services. This is one of the major challenges that the country faces in order to achieve SDG heath targets by 2030. This Hits highlights steps taken to overcome challenges especially in the face of epidemiological change in disease burden that is slowly taking place in the country.
World Psychiatric Association - Health Systems' Performance Roundtable cana...Université de Montréal
This was part of a roundtable presentation on health systems' performance around the world, focusing on psychiatric care. My contribution was a survey of the Canadian health care system's performance.
This document discusses improving health information systems for monitoring non-communicable diseases in the Pacific region. It outlines the importance of health information systems and cause-specific mortality data for policymaking and evaluating disease prevention programs. Current issues with mortality data quality in many Pacific countries are described, where many deaths occur outside of health institutions and cause of death is often misclassified. Efforts underway to improve data quality include training doctors in cause of death certification and developing national strategies to strengthen civil registration and vital statistics systems.
Risk profiling, multiple long term conditions & complex patients, integrated ...Dr Bruce Pollington
Dr Bruce Pollington web-ex presentation to LTC QIPP programme
Utilising risk profiling, and risk stratification to identify patients with multiple long term conditions requiring complex care through integrated care teams.
This document describes a quality improvement project to reduce readmissions among uninsured cardiac patients at a large public hospital on the U.S.-Mexico border. The project implemented a protocol to provide uninsured patients with a 30-day supply of essential medications upon discharge. Retrospective data showed high readmission rates and costs prior to the protocol. After implementing the protocol, zero readmissions occurred during the study period. The protocol demonstrated the value of ensuring uninsured patients can access needed medications to improve outcomes and reduce costly readmissions.
This document discusses the importance of preventive healthcare and screening for early detection of diseases. It provides guidance on screening recommendations and intervals for various common conditions like cancer, cardiovascular disease, diabetes, osteoporosis and others. The risks and benefits of different screening tests are presented to facilitate informed decision making. Emphasis is placed on integrating preventive services and chronic disease management into primary care to improve outcomes and reduce healthcare costs.
This document discusses the Heartland Telehealth Resource Center (HTRC), which provides technical assistance and resources to implement telehealth programs for rural and underserved communities in Kansas, Missouri, and Oklahoma. It is one of 14 regional telehealth centers funded by the U.S. Department of Health and Human Services. The HTRC works with rural communities, community health centers, and rural health clinics to help organizations overcome barriers and advance telehealth education. It provides consultation services, webinars, workshops and online resources to support telehealth implementation. The document also describes several telehealth programs operated by the University of Kansas Medical Center that provide behavioral health services to children, schools and disaster-affected communities using a telehealth model.
Indonesia has a mixed health system with both public and private provision of care. Key achievements include increased life expectancy and reductions in communicable disease rates. However, challenges remain such as the dual burden of disease, natural disasters, weak health information systems, and high out-of-pocket expenditures. Future prospects include expanding the use of telemedicine, incentivizing an even workforce distribution, and passing more legislation to clarify the health system framework.
Jacquie White, Deputy Director of NHS England Long Term Conditions, Older People & End of Life Care and Claire Cordeaux SIMUL8 Executive Director for Health & Social Care were invited by Centers for Medicare & Medicaid Services to discuss how NHS England work in chronic disease.
The Thailand HiT reports that sustained political commitment to the health of the population since the 1970s has resulted in significant investment in health infrastructure, in particular primary health care, district and provincial referral hospitals, and strengthened the overall functioning of the Thai health system. After Thailand achieved universal health coverage in 2002, public expenditure on health significantly increased from 63% to 77% and out-of-pocket expense was reduced from 27.2% to 12.4% of the total health spending in 2011.
This paper presents analysis of a Kent ‘whole population’ dataset, linking wholepopulation demographics with activity and cost data for the population from acute, community, mental health and social care providers. The data helps commissioners to understand the impact of different selections methods for people with ‘very complex’ health and social care needs, particularly in relation to the development of a LTC year of care currency.
This document should be seen alongside the ‘Recovery, Rehabilitation and Reablement – step-by-step guide’ which describes how providers can carry out the audit in their own organisation. Other documents and learning materials This document is part of a suite of learning materials being produced by the LTC Year of Care Commissioning Programme to support the spread and adoption of capitated budgets for people with complex care needs.
This second edition of the health system review of Philippines shows the major changes that have occurred over the 7 years since the last review. Channelling of funds from sin tax to Health has shown unprecedented levels of finances are now available for UHC. PhilHealth has dramatically increased coverage of people as well as service providers that it works with from both government and non-government sectors. However major challenges remain; regional and socioeconomic disparities in the availability and accessibility of resources are prominent and there is a need to improve regulation of service providers. Philippines HiT reports on the current health system reforms undertaken including challenges of incorporating primary health care as in the overall health architecture of the country.
This is primarily based on a chapter from our most recent publication.
I want to acknowledge the authors of the chapter:
Melisa Tan, Victoria Haldane, Sue-Anne Toh & Helena Legido-Quigley from NUS
Martin McKee from LSHTM
Summary of the current 4 main NCDs situation in Asia including risk factors
Examples of health system response
Challenges
Η διαχείριση των μειζόνων συμπεριφορικών παραγόντων κινδύνου στην ΠΦΥEvangelos Fragkoulis
Παρουσίαση μου στα πλαίσια του Consensus Meeting: "Η διαχείριση και ο έλεγχος των Μείζονων Συμπεριφορικών Παραγόντων Κινδύνου για την Υγεία: η συμβολή νέων "εργαλείων" για την αντιμετώπιση τους", Ελληνική Επιστημονική Εταιρεία Οικονομίας και Πολιτικής της Υγείας, Ξυλόκαστρο 6-8 Ιουλίου 2018
Η συνεισφορά της Γενικής Οικογενειακής Ιατρικής στη ΦαρμακοεπιδημιολογίαEvangelos Fragkoulis
The document discusses the contribution of general/family medicine to pharmacoepidemiology. It describes pharmacoepidemiology as the study of drug use and effects in large populations to support rational drug use and improve health outcomes. Primary care physicians are well-positioned to identify drug safety issues and provide data from electronic health records for pharmacoepidemiology research. Routinely collected healthcare data can be used to study drug patterns, safety, and effectiveness in real-world populations.
Mobility is Medicine
Loretta Schoen Dillon, PT, DPT, MS
Director of Clinical Education and Clinical Associate Professor
UTEP Physical Therapy Program
Mano y Corazón Binational Conference of Multicultural Health Care Solutions, El Paso, Texas, September 27-28, 2013
Human Genomics and Public Health in a Global World: Challenges for Low & Midd...Human Variome Project
This document discusses challenges for low and middle income countries regarding human genomics and public health in a global context. It notes that while genomics activity is increasing in about 50 countries, it remains fragmented without systematic monitoring or links to health policymakers. Five priorities for international genomics are identified: building an evidence base for genomic medicine, addressing health disparities, managing diverse patient populations, implications for medical education, and coordination across diseases. The document argues for greater global collaboration to improve access, establish standards, and promote equity and justice.
International Health Policy and Practice: Comparing the U.S. and Canada on Ac...The Commonwealth Fund
Dr. Eric Schneider's presentation on international health policy and practice. This presentation was delivered at the 2015 AcademyHealth Annual Research Meeting on June 14, 2015.
The People’s Republic of China has made great achievements in improving health status over the past six decades, mainly due to the government’s commitment to health, provision of cost effective public health programmes, growing coverage of health financial protection mechanisms and investments in an extensive health-care delivery network.
Population Health Management PresentationCANorfolk
The document discusses population health management (PHM) and its role in supporting integrated care systems (ICS) in the UK. Key points:
- ICSs will be established everywhere by 2021 to integrate primary/specialist care, physical/mental health, and health/social care.
- PHM solutions will help ICSs understand health needs and match NHS services accordingly through data analysis.
- PHM aims to improve population health through proactive, data-driven care that prevents illness and reduces health inequalities.
Mike Bewick: Primary care transformation: what for and whyThe King's Fund
Mike Bewick looks at the challenges currently facing primary care in the NHS, including unacceptable variations in care, oversupply and undersupply in the health workforce, and the impact of an ageing population. What would great primary care look like in an ideal world?
Professor Liam Smeeth: Big Data, 30 June 2014Nuffield Trust
- The Farr Institute was established in 2012 with £19 million in funding to conduct health informatics research using large electronic health databases. It includes centers in London, Scotland, Wales, and Manchester.
- Examples are given of research using big data that would not otherwise be possible, such as studies of MMR vaccination and autism and the relationship between BMI and cancer risk.
- Challenges of randomized trials include recruitment, generalizability, and costs, and electronic health records may help address these challenges through trials like one testing text message reminders for flu vaccines.
This presentation has made to health workers who have more than two decades of experience of managing/implementing public health programs in Nepal, especially at district level and below.
Alzheimer's disease is a progressive brain disorder that destroys memory and cognitive skills. Dr. Alois Alzheimer first described it in 1906 after examining a woman with dementia. The disease is characterized by beta-amyloid plaques and neurofibrillary tangles in the brain. Current treatments aim to improve symptoms but do not stop the underlying disease process. Researchers are exploring therapies targeting amyloid and tau proteins as well as other mechanisms to find a cure.
The document provides an overview of dementia in the 21st century, including definitions, types, symptoms, progression, treatment, and future outlook. It discusses the increasing prevalence and costs of dementia globally. Key points covered include the cognitive domains impaired in dementia, diagnostic criteria and stages, distinguishing activities of daily living from instrumental activities, common behavioral changes, pharmacological and non-pharmacological interventions, and risk factors. The document also explores causes of dementia such as oxidative stress and inflammation and provides hope that effective treatments may be available within the next decade.
This document describes a quality improvement project to reduce readmissions among uninsured cardiac patients at a large public hospital on the U.S.-Mexico border. The project implemented a protocol to provide uninsured patients with a 30-day supply of essential medications upon discharge. Retrospective data showed high readmission rates and costs prior to the protocol. After implementing the protocol, zero readmissions occurred during the study period. The protocol demonstrated the value of ensuring uninsured patients can access needed medications to improve outcomes and reduce costly readmissions.
This document discusses the importance of preventive healthcare and screening for early detection of diseases. It provides guidance on screening recommendations and intervals for various common conditions like cancer, cardiovascular disease, diabetes, osteoporosis and others. The risks and benefits of different screening tests are presented to facilitate informed decision making. Emphasis is placed on integrating preventive services and chronic disease management into primary care to improve outcomes and reduce healthcare costs.
This document discusses the Heartland Telehealth Resource Center (HTRC), which provides technical assistance and resources to implement telehealth programs for rural and underserved communities in Kansas, Missouri, and Oklahoma. It is one of 14 regional telehealth centers funded by the U.S. Department of Health and Human Services. The HTRC works with rural communities, community health centers, and rural health clinics to help organizations overcome barriers and advance telehealth education. It provides consultation services, webinars, workshops and online resources to support telehealth implementation. The document also describes several telehealth programs operated by the University of Kansas Medical Center that provide behavioral health services to children, schools and disaster-affected communities using a telehealth model.
Indonesia has a mixed health system with both public and private provision of care. Key achievements include increased life expectancy and reductions in communicable disease rates. However, challenges remain such as the dual burden of disease, natural disasters, weak health information systems, and high out-of-pocket expenditures. Future prospects include expanding the use of telemedicine, incentivizing an even workforce distribution, and passing more legislation to clarify the health system framework.
Jacquie White, Deputy Director of NHS England Long Term Conditions, Older People & End of Life Care and Claire Cordeaux SIMUL8 Executive Director for Health & Social Care were invited by Centers for Medicare & Medicaid Services to discuss how NHS England work in chronic disease.
The Thailand HiT reports that sustained political commitment to the health of the population since the 1970s has resulted in significant investment in health infrastructure, in particular primary health care, district and provincial referral hospitals, and strengthened the overall functioning of the Thai health system. After Thailand achieved universal health coverage in 2002, public expenditure on health significantly increased from 63% to 77% and out-of-pocket expense was reduced from 27.2% to 12.4% of the total health spending in 2011.
This paper presents analysis of a Kent ‘whole population’ dataset, linking wholepopulation demographics with activity and cost data for the population from acute, community, mental health and social care providers. The data helps commissioners to understand the impact of different selections methods for people with ‘very complex’ health and social care needs, particularly in relation to the development of a LTC year of care currency.
This document should be seen alongside the ‘Recovery, Rehabilitation and Reablement – step-by-step guide’ which describes how providers can carry out the audit in their own organisation. Other documents and learning materials This document is part of a suite of learning materials being produced by the LTC Year of Care Commissioning Programme to support the spread and adoption of capitated budgets for people with complex care needs.
This second edition of the health system review of Philippines shows the major changes that have occurred over the 7 years since the last review. Channelling of funds from sin tax to Health has shown unprecedented levels of finances are now available for UHC. PhilHealth has dramatically increased coverage of people as well as service providers that it works with from both government and non-government sectors. However major challenges remain; regional and socioeconomic disparities in the availability and accessibility of resources are prominent and there is a need to improve regulation of service providers. Philippines HiT reports on the current health system reforms undertaken including challenges of incorporating primary health care as in the overall health architecture of the country.
This is primarily based on a chapter from our most recent publication.
I want to acknowledge the authors of the chapter:
Melisa Tan, Victoria Haldane, Sue-Anne Toh & Helena Legido-Quigley from NUS
Martin McKee from LSHTM
Summary of the current 4 main NCDs situation in Asia including risk factors
Examples of health system response
Challenges
Η διαχείριση των μειζόνων συμπεριφορικών παραγόντων κινδύνου στην ΠΦΥEvangelos Fragkoulis
Παρουσίαση μου στα πλαίσια του Consensus Meeting: "Η διαχείριση και ο έλεγχος των Μείζονων Συμπεριφορικών Παραγόντων Κινδύνου για την Υγεία: η συμβολή νέων "εργαλείων" για την αντιμετώπιση τους", Ελληνική Επιστημονική Εταιρεία Οικονομίας και Πολιτικής της Υγείας, Ξυλόκαστρο 6-8 Ιουλίου 2018
Η συνεισφορά της Γενικής Οικογενειακής Ιατρικής στη ΦαρμακοεπιδημιολογίαEvangelos Fragkoulis
The document discusses the contribution of general/family medicine to pharmacoepidemiology. It describes pharmacoepidemiology as the study of drug use and effects in large populations to support rational drug use and improve health outcomes. Primary care physicians are well-positioned to identify drug safety issues and provide data from electronic health records for pharmacoepidemiology research. Routinely collected healthcare data can be used to study drug patterns, safety, and effectiveness in real-world populations.
Mobility is Medicine
Loretta Schoen Dillon, PT, DPT, MS
Director of Clinical Education and Clinical Associate Professor
UTEP Physical Therapy Program
Mano y Corazón Binational Conference of Multicultural Health Care Solutions, El Paso, Texas, September 27-28, 2013
Human Genomics and Public Health in a Global World: Challenges for Low & Midd...Human Variome Project
This document discusses challenges for low and middle income countries regarding human genomics and public health in a global context. It notes that while genomics activity is increasing in about 50 countries, it remains fragmented without systematic monitoring or links to health policymakers. Five priorities for international genomics are identified: building an evidence base for genomic medicine, addressing health disparities, managing diverse patient populations, implications for medical education, and coordination across diseases. The document argues for greater global collaboration to improve access, establish standards, and promote equity and justice.
International Health Policy and Practice: Comparing the U.S. and Canada on Ac...The Commonwealth Fund
Dr. Eric Schneider's presentation on international health policy and practice. This presentation was delivered at the 2015 AcademyHealth Annual Research Meeting on June 14, 2015.
The People’s Republic of China has made great achievements in improving health status over the past six decades, mainly due to the government’s commitment to health, provision of cost effective public health programmes, growing coverage of health financial protection mechanisms and investments in an extensive health-care delivery network.
Population Health Management PresentationCANorfolk
The document discusses population health management (PHM) and its role in supporting integrated care systems (ICS) in the UK. Key points:
- ICSs will be established everywhere by 2021 to integrate primary/specialist care, physical/mental health, and health/social care.
- PHM solutions will help ICSs understand health needs and match NHS services accordingly through data analysis.
- PHM aims to improve population health through proactive, data-driven care that prevents illness and reduces health inequalities.
Mike Bewick: Primary care transformation: what for and whyThe King's Fund
Mike Bewick looks at the challenges currently facing primary care in the NHS, including unacceptable variations in care, oversupply and undersupply in the health workforce, and the impact of an ageing population. What would great primary care look like in an ideal world?
Professor Liam Smeeth: Big Data, 30 June 2014Nuffield Trust
- The Farr Institute was established in 2012 with £19 million in funding to conduct health informatics research using large electronic health databases. It includes centers in London, Scotland, Wales, and Manchester.
- Examples are given of research using big data that would not otherwise be possible, such as studies of MMR vaccination and autism and the relationship between BMI and cancer risk.
- Challenges of randomized trials include recruitment, generalizability, and costs, and electronic health records may help address these challenges through trials like one testing text message reminders for flu vaccines.
This presentation has made to health workers who have more than two decades of experience of managing/implementing public health programs in Nepal, especially at district level and below.
Alzheimer's disease is a progressive brain disorder that destroys memory and cognitive skills. Dr. Alois Alzheimer first described it in 1906 after examining a woman with dementia. The disease is characterized by beta-amyloid plaques and neurofibrillary tangles in the brain. Current treatments aim to improve symptoms but do not stop the underlying disease process. Researchers are exploring therapies targeting amyloid and tau proteins as well as other mechanisms to find a cure.
The document provides an overview of dementia in the 21st century, including definitions, types, symptoms, progression, treatment, and future outlook. It discusses the increasing prevalence and costs of dementia globally. Key points covered include the cognitive domains impaired in dementia, diagnostic criteria and stages, distinguishing activities of daily living from instrumental activities, common behavioral changes, pharmacological and non-pharmacological interventions, and risk factors. The document also explores causes of dementia such as oxidative stress and inflammation and provides hope that effective treatments may be available within the next decade.
This document discusses the importance of working on interdisciplinary teams to care for the growing population of individuals with dementia. It emphasizes the need for social workers to practice mindfulness and minimize power imbalances when working with this vulnerable group. Key points include:
- Dementia is a major public health issue due to the aging population and increased longevity. Interdisciplinary teams are crucial to address the complex needs of those with dementia.
- Social workers must be self-aware and culturally sensitive to reduce power dynamics and oppression in their work. Building trust and respecting clients' dignity is important.
- Person-centered care that acknowledges individual needs and autonomy, even as cognition declines, improves quality of life for those with dementia. Interdisciplinary
Alzheimer’s disease is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually even the ability to carry out the simplest tasks of daily living. In most people with Alzheimer’s, symptoms first appear after age 60. Alzheimer’s disease is the most common cause of dementia among older people.
El documento describe la enfermedad de Alzheimer, incluyendo sus causas, tipos, síntomas, pruebas de diagnóstico, tratamiento, pronóstico y prevención. La enfermedad de Alzheimer causa pérdida de memoria y otros problemas cognitivos, y los factores de riesgo incluyen la edad y tener antecedentes familiares de la enfermedad. No existe una cura, pero los tratamientos pueden ayudar a manejar los síntomas.
There are approximately 5.3 million Americans diagnosed with Alzheimer's dementia currently. This represents 14% of those over 71 and over 50% of those over 85. The most common form is Alzheimer's disease, which causes brain changes resulting in memory loss, thinking impairment, and behavioral changes. While aging increases risk, Alzheimer's is not normal aging, and other conditions like strokes can also cause dementia.
Presentation made by Dr. Michael Heneka at the Alzheimer Research Forum Live Webinar of March 20, 2013 - http://www.alzforum.org/res/for/journal/detail.asp?liveID=209
Dementia is a progressive decline in cognitive function including memory loss and at least one other cognitive deficit. Alzheimer's disease is the most common cause of dementia, characterized by plaques and tangles in the brain. Symptoms start with memory problems and gradually worsen to include problems with language, orientation, judgment, and ability to perform daily tasks. Dementia progresses through mild, moderate, and severe stages with increasing impairment. It can be caused by reversible or irreversible factors and is diagnosed through cognitive assessments and medical tests.
¿ES LA ENFERMEDAD DE ALZHEIMER CAUSADA POR UNA INFECCIÓN?Guillermo Rivera
La hipótesis de un origen infeccioso de la enfermedad de alzheimer se discute desde hace 30 años. Existe numerosa literatura que vincula diversos agentes infecciosos, como son el virus del herpes y algunas espiroquetas y su posible relación con el alzheimer. Estas evidencias sobre la existencia de infecciones en pacientes con la enfermedad de Alzheimer abre un nuevo campo de investigación de la etiología de esta enfermedad.
This document provides an overview of Alzheimer's disease including its causes, symptoms, stages, diagnosis, and treatment approaches. It discusses how Alzheimer's is characterized by plaques and tangles in the brain made up of beta-amyloid and tau proteins. Current treatment aims to improve cognitive function and behaviors through cholinesterase inhibitors and memantine, though none can stop or reverse the disease. Non-pharmacological interventions like education, communication, and stimulation therapies may provide additional support.
A patient has a history of recurrent gum bleeding since childhood. While platelet counts and coagulation tests are normal, an inherited platelet disorder is suspected. The doctor's diagnostic approach would include a detailed bleeding history, physical exam looking for bruises/petechiae, and first-line screening tests like a bleeding time and platelet function analyzer. Further specific tests may include light transmission aggregometry to assess platelet aggregation in response to various agonists and help identify potential defects in adhesion, activation, secretion or aggregation. Interpreting the different waveforms is important to determine abnormalities consistent with disorders like Glanzmann's thrombasthenia or storage pool disease.
New treatment trends in alzheimer diseaseSarath Menon
This document summarizes new treatment trends in Alzheimer's disease. It discusses current treatments for mild-moderate Alzheimer's like donepezil, rivastigmine, and galantamine which are cholinesterase inhibitors. Memantine is used for more severe Alzheimer's as an NMDA receptor antagonist. Experimental therapies discussed include vaccines, secretase inhibitors, and stem cell therapy. Lifestyle factors like diet, exercise, and social support are also reviewed for prevention and management of Alzheimer's symptoms.
Professor Tony Elliott presents information on dementia and Alzheimer's disease, including:
1) Dementia is characterized by memory loss and functional decline, while Alzheimer's is the most common cause of dementia.
2) The prevalence of dementia doubles every 5 years after age 65, affecting 5% of those over 65 and up to 32% of those over 90.
3) The brain changes in Alzheimer's include plaques, tangles, and loss of connections between neurons.
4) Risk factors include age, family history, and genetic factors like ApoE4, while preventative factors include diet, exercise, and mental activity.
The document discusses various types of dementia, their causes and symptoms. It describes Alzheimer's disease, vascular dementia, dementia caused by Parkinson's disease, Huntington's disease, Pick's disease, Creutzfeldt-Jakob disease, Wernicke-Korsakoff syndrome, normal pressure hydrocephalus, mixed dementia, and dementia not otherwise specified. Symptoms include memory loss, confusion, problems with language and motor skills. Causes include neurological disorders, traumatic brain injuries, infections, substance abuse, and unknown etiologies.
This document provides an overview of dementia, including:
- The DSM-IV criteria for diagnosing dementia which requires memory impairment plus deficits in other cognitive domains as well as functional impairment.
- The most common causes of dementia, with Alzheimer's disease accounting for 70% of cases and vascular dementia 10-15%.
- Methods for diagnosing dementia including clinical assessments, neuropsychological testing, brain imaging, and lab tests to identify reversible causes.
- Approaches to managing dementia focusing on reducing cognitive and behavioral symptoms, slowing progression, and treating underlying conditions. Pharmacological options include cholinesterase inhibitors and memantine to alleviate symptoms.
The document discusses the Play web framework and how it compares to traditional Java web development using servlets and XML configuration. Play allows building web applications in Java without servlets and XML by embedding the web framework directly into the code using a convention over configuration approach. It also supports features like asynchronous programming and websockets. Several companies that have used Play in production are mentioned.
Alzheimer's disease is the most common form of dementia. It is a neurodegenerative disease that causes deterioration of the brain and destruction of nerve cells. This leads to a loss of functioning in the brain and difficulties sending proper signals. While the cause is unknown, family history increases risk. Alzheimer's affects the brain, causing shrinkage and clumps/tangles that impair intellectual functioning. Symptoms worsen over 7 stages, from mild memory loss to severe impairment. Currently there is no cure, but drugs can help treat some symptoms.
Jacquie White, Deputy Director of NHS England Long Term Conditions, Older People & End of Life Care and Dr Eileen Pepler, Academic, Researcher and Consultant in the Canadian Healthcare will discuss how NHS England work in chronic disease is being translated into a Canadian context.
Greece: Primary Care in a time of crisis. 2nd VdGM Forum, Dublin 2015Evangelos Fragkoulis
2nd Vasco Da Gama Movement Forum, Dublin 2015
The Effect of the Economic Crisis on the Health Systems of the peripheral countries: Greece, Ireland, Spain, Portugal and Italy.
This document provides an agenda and materials for a workshop on personalization for long term conditions. The agenda includes sessions on local priorities, national overviews, interactive exercises, simulation modeling, and developing declarations. Key topics covered include person-centered care, long term conditions, coordinated rather than integrated care, strategies for embedding personal care planning, and new models of care. Simulation modeling is demonstrated as a way to test new integrated care service models and discharge planning. The workshop aims to support moving care delivery toward a more whole-person approach.
Long term conditions like diabetes place a large burden on healthcare systems. A study in Yorkshire examined experiences providing care for long term conditions. It found that telehealth interventions can reduce hospital admissions, bed days, and costs while improving patients' quality of life. The Whole System Demonstrator Programme trial of telehealth and telecare in various UK regions showed a 45% reduction in mortality rates and 20% fewer emergency admissions among other benefits. Telehealth represents an opportunity to deliver more specialized care while reducing strain on hospitals and caregivers.
This document discusses Elder Medical, a division of IPC Healthcare that provides elder care services across the continuum of care. It outlines Elder Medical's focus on personalized medicine through risk assessment, prevention, early detection, accurate diagnosis, targeted treatment, disease management, and seamless information sharing. The document discusses the growing elder population and increasing prevalence of chronic diseases as attractive markets. It also discusses integrated delivery networks and partnerships that can improve coordination of care, reduce costs, and increase quality. The role of Elder Medical in providing medical management and care coordination for post-acute care facilities is highlighted.
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World Alzheimer Report 2016: Improving healthcare for people living with dementia
1. World Alzheimer Report 2016:
Improving healthcare for people living
with dementia
COVERAGE, QUALITYAND COSTS NOW AND IN THE FUTURE
2016 Alzheimers NZ Biennial Conference and 19th Asia Pacific
Regional Conference of Alzheimer’s Disease International,
Wellington, New Zealand.
Adelina Comas-Herrera
Personal Social Services Research Unit (PSSRU)
London School of Economics and Political Science
a.comas@lse.ac.uk
@adelinacohe
1
2. About the report:
• Authors: Martin Prince,
Adelina Comas-
Herrera, Martin Knapp,
Maelenn Guerchet,
Maria Karagiannidou.
• Commissioned by
Alzheimer’s Disease
International.
2
www.alz.co.uk/worldreport2016
3. Disclaimer
The opinions, comments and interpretations of all the
material presented here are my own and not those of my
current and former co-authors and research funders.
3
4. THE NUMBER OF PEOPLE
LIVING WITH DEMENTIA IS
GROWING ALL OVER THE
WORLD
And at a much faster pace in low- and middle-income
countries
4
5. The majority of people with dementia live in
low and middle income countries (LMICs)
www.alz.co.uk/worldreport2015
7. Source: estimates from the World Alzheimer Report 2015,
Prince et al.
7
Canada, 59%
China, 70%
Indonesia, 87%
Mexico, 95%
New Zealand, 60%
South Africa, 48%
South Korea, 110%
Switzerland, 45%
0% 20% 40% 60% 80% 100% 120%
Canada
China
Indonesia
Mexico
New Zealand
South Africa
South Korea
Switzerland
% change in the numbers of people living with dementia, 2015 to 2030
8. HOW TO EXPAND CARE
SUSTAINABLY
Dementia Healthcare Pathways: exploring task-shifting
and task sharing
8
9. Why do we start with dementia healthcare
pathways?
• Diagnostic: gateway for access to health & social care.
But low coverage: 40-50% in most HIC, around 5-10% in
most LMIC
• Lack of specialist services: very few in LMIC. In HIC,
struggle to keep up with rapidly increasing numbers
• Even interventions with a strong evidence-base (e.g.
anti-dementia drugs) are not being delivered to all who
might benefit
• Most health expenditure for people with dementia is for
hospital care: potential to reduce avoidable
hospitalisations
9
10. Two different challenges:
• High Income Countries: Adapting well-established
health systems, dominated by a tradition of “curative”
health care, to the needs of increasing numbers of people
with dementia.
• Low and Middle Income Countries: Developing new
health care provision to meet the needs of increasing
numbers of people with dementia (and other chronic
conditions).
• Context: rapid ageing, competing demands and low resource
availability.
10
11. How can we do better in healthcare for
people with dementia?
• Improve diagnosis rates, and access to:
• Post-diagnostic support
• Continuing care and treatments that moderate symptoms (anti-
dementia drugs, non-pharmacological therapies)
• Prevention of additional risks (falls, UTIs, etc).
• End-of-life care
• Ensure that access to healthcare for other comorbidities
is timely and appropriate for a person with dementia
• In the event of new treatments that alter course of
dementia, we need healthcare systems capable of
delivering them.
11
12. Expanding healthcare for people with dementia:
task-shifting and task-sharing
• Task-shifting: delegating selected tasks to existing
or new health professional cadres with either less
training or narrowly tailored training.
• Task-sharing: in reality, almost all task-shifted
models of service delivery include an element of
task-sharing between specialist and non-specialist
services.
12
13. Task-shifting (contd.)
• Shifting tasks from higher to lower skilled workers (eg from a
neurologist specialist doctor to a general practitioner)
• Shifting tasks from workers with general training to workers with specific
training for a particular task (e.g. from a GP to a dementia case
manager).
• Assumptions:
• The unit cost of task-shifted option is cheaper, and that the quality of care
and outcomes are equivalent.
• Less-specialised staff are more numerous and can be trained more quickly: the
dementia healthcare workforce could be scaled up more quickly.
13
14. Evidence on task-shifting so far:
With adaptation and appropriate training and supervision, it
is feasible for interventions usually delivered by specialist
doctors to be taken on by non-specialists (and non-doctors)
without adverse effect on clinical outcomes (growing
evidence of moderate quality).
14
15. Proposal: a task-shifted dementia
healthcare pathway
1. Diagnostic (mostly primary care, GPs and case
managers)
2. Initial treatment and post-diagnostic support:
1. Assessment for anti-dementia drugs
2. Post-diagnostic support package
3. Carer training and support
3. Continuing care
1. Anti-dementia medication reviews
2. Management of behavioural and psychological symptoms
3. Case management
4. End of Life care
Complex cases referred to specialist pathway
15
17. Costing a task-shifted dementia
healthcare pathway: 2015-2030
Methods:
• Demographic & prevalence data to calculate N of people
with dementia in 2015 and 2030.
• Assuming diagnostic rates increase (50% in 2015 to 75%
in 2030 for HIC; 10% to 50% in LMIC).
• Apply unit costs to different elements of the care pathway.
• Assume real costs of care increase in line with GDP per
capita.
• For HIC we also compared with the cost of a “typical”
specialist care pathway.
• We only cost dedicated dementia pathway, not all
health care use by people with dementia.
17
18. Comparable unit costs of care?
• Difficult to obtain unit costs for most services and most
countries.
• Calculated “international unit costs”:
• Used Unit costs of Care from the UK (PSSRU Unit Costs 2015 and
DH) to obtain the relative cost difference between care professionals
(and interventions/services/tests/drugs).
• Used WHO Choice 2008 unit costs of care data to obtain the relative
unit costs differences between countries (in PPP International $ and
including the UK).
• Adjusted the “between country cost differences” for changes in PPP
2008 to 2015, between each country and the UK.
• Adjusted the 2015 UK Unit costs to reflect country differences and
applied exchange rate to US$ 2015.
• Where local data was available (e.g. costs of GP, specialists,
nurses, or for particular drugs or tests, this was used).
18
19. Some costing considerations:
• The relative cost of different healthcare professionals is
not the same (i.e. in the UK GPs unit costs are higher
than specialists).
• Not all professionals are the same: most primary care
doctors in rural China do not have a university degree.
• There are huge differences in the costs of drugs,
depending on patent durations, policies with regards
generics and additional prescription fees.
• The costs of equipment such as MRI scans can also be
very different in LMIC and HIC.
19
20. Proportional contribution to the costs of
different parts of the pathway, 2015.
Canada China Indonesia Mexico South
Africa
South Korea Switzerland
Specialist Task-
shifted
Task-
shifted
Task-
shifted
Task-
shifted
Task-
shifted
Specialist Task-
shifted
Specialist Task-
shifted
Staff 67.9% 50.4% 4.6% 16.6% 42.8% 15.2% 8.6% 4.2% 39.1% 23.3%
Neuroimaging 7.4% 2.5% 1.4% 1.6% 0.5% 0.5% 1.1% 0.2% 6.0% 1.6%
Anti-dementia drugs 19.7% 34.0% 91.9% 81.5% 54.7% 84.0% 88.8% 93.4% 48.0% 63.1%
Hospital stays 5.0% 9.6% 1.3% 0.2% 1.9% 0.3% 1.5% 1.8% 5.4% 8.0%
Other 0.1% 3.5% 0.7% 0.1% 0.0% 0.1% 0.0% 0.4% 1.4% 4.0%
20
21. Cost of the pathways in 2030, with current local drug
prices vs. England drug prices (in US$),
assuming we reach 50% diagnosticrate in HIC and 75% in LMIC
If all countries had the same drug prices as England’s prices today (uprated)
Canada China Indonesia Mexico South
Africa
South Korea Switzerland
2030 Specialist Task-
shifted
Task-
shifted
Task-
shifted
Task-
shifted
Task-
shifted
Specialist Task-
shifted
Specialist Task-
shifted
Cost of
pathways
(millions)
629 311 260 24 27 5 213 129 186 103
Cost per
person
with
dementia
761 377 16 11 17 17 212 120 960 530
21
Current drug prices, uprated
Canada China Indonesia Mexico South
Africa
South Korea Switzerland
2030 Specialist Task-
shifted
Task-
shifted
Task-
shifted
Task-
shifted
Task-
shifted
Specialist Task-
shifted
Specialist Task-
shifted
Cost of
pathways
(millions)
756 438 2,660 384 48 26 1,652 1,568 334 251
Cost per
person
with
dementia
914 530 164 169 30 93 1,641 1,558 1,723 1,294
23. Canada:
• National clinical standards already support a task-shifted
approach with central role for primary care.
• Despite national clinical guidelines, variability in
implementation across and within regions.
• Difficulties with access to care in rural and remote areas
(role for technology?).
• Higher rates of undiagnosed dementia for people in
nursing homes, suggesting poor access to healthcare.
• Lack of a National Dementia Strategy makes it difficult to
coordinate research and programmes to improve care.
23
24. Mexico
• Fragmented healthcare financing and provision system,
resulting in unequal coverage.
• Relatively low availability of healthcare services and small
role of primary care.
• Consolidated drug purchasing helps ensure affordable
medication.
• National Dementia Plan: emphasis on training of staff and
increasing public awareness.
• To deliver improved dementia healthcare coverage it
would be fundamental to ensure consistency across the
insurance schemes and to strengthen the role of primary
care.
24
26. Conclusions (1): affordability
• The costs of the dementia healthcare pathways are
relatively low, compared to overall health spending.
• In countries where generics are not available or not widely
prescribed, specially if wages are low, anti-dementia drugs
may not be cost-effective.
• If, by 2030, drug costs were low, the cost of implementing
the task-shifted pathway would be 40% lower than the
specialist pathway (in all the HIC modelled).
26
27. Healthcare system features needed to improve coverage
sustainably:
• Universal Health Coverage,
• a central role (gate-keeping) for primary care,
• low out-of-pocket payments,
• dedicated dementia plans
• improved dementia training for all healthcare staff
• access to drugs at generic prices
27
Conclusions (2):
Necessary healthcare system conditions
28. Questions for future research:
• Modelling the impact of improving coverage of diagnostic
and continuing care using a task-shifted model:
• What will be the impact on improved outcomes (cognition, quality
of life, etc.)?
• Does it result in a reduction in avoidable admissions and other
“bad costs of care”?
• We still know relatively little about what works in dementia
care, treatment and support.
• And we know even less about how to translate evidence to
different countries with different economic contexts.
• Extending the pathways to cover all the care, treatment
and support for people with dementia and their carers
(health, social care, family care).
28