Personal connected health is currently characterized by limited thought leadership, insufficient coordination and collaboration, and a lack of awareness and understanding of the full potential by all stakeholders: public, providers, policymakers, industry and patients. The Personal Connected Health Alliance is defining the the field of personal connected health to inspire market and policy innovation, research and collective action for sustained adoption of personal connected health technology. The vision is better health and well being for all through increased personal responsibilities and connectivity as well as improved care delivery enabled by technology.
The Internet of Things (IoT) is the latest buzzword out of the interface between information technology and business. As technologies like Bluetooth and sensors enable connections between devices and networks, innovation has brought connections between devices and a human interface. In healthcare, this has been termed the Internet of Medical Things or Healthy things. Medical devices and consumer health devices generate data which can be analyzed, synthesized and displayed for the consumer and healthcare provider to get a broader picture of one’s health. Everything from fitness devices to glucose monitors can give us information about our current health status as never before. How this will integrate into a clinician’s workflow is a new journey of discovery as medical practice catches up with these innovations.
HxRefactored 2015: Charles Boicey "Interoperability Exercise, Triple Store & ...HxRefactored
Charles Boicey, RN and Enterprise Analytics Architect for Stony Brook Medicine shares how RDF Triples can reconcile data from multiple and disparate sources to unlock great insight.
To make remote monitoring devices interoperable, we must examine a variety of use cases and the current evidence of their effectiveness. The presentation is from the January 2020 IHE Connectathon in Cleveland, Oho.
The Internet of Things (IoT) is the latest buzzword out of the interface between information technology and business. As technologies like Bluetooth and sensors enable connections between devices and networks, innovation has brought connections between devices and a human interface. In healthcare, this has been termed the Internet of Medical Things or Healthy things. Medical devices and consumer health devices generate data which can be analyzed, synthesized and displayed for the consumer and healthcare provider to get a broader picture of one’s health. Everything from fitness devices to glucose monitors can give us information about our current health status as never before. How this will integrate into a clinician’s workflow is a new journey of discovery as medical practice catches up with these innovations.
HxRefactored 2015: Charles Boicey "Interoperability Exercise, Triple Store & ...HxRefactored
Charles Boicey, RN and Enterprise Analytics Architect for Stony Brook Medicine shares how RDF Triples can reconcile data from multiple and disparate sources to unlock great insight.
To make remote monitoring devices interoperable, we must examine a variety of use cases and the current evidence of their effectiveness. The presentation is from the January 2020 IHE Connectathon in Cleveland, Oho.
An edited version of my presentation at the Mobile Health Workshop for Engineers and PhD scholars at National Institute of Technology Surathkal, Mangalore.
2016 IBM Interconnect - medical devices transformationElizabeth Koumpan
Emerging technologies such as Internet of Things, 3D Printing are driving the creation of new business models and forcing the Industry for transformation. The product centric model where the Industry main objective was to develop the device, is moving to software and services model, with the focus on Big Data & Analytics, Integration and Cloud.
The maturation of technologies such as social, mobile, analytics, cloud, 3D printing, bio- and nanotechnology are rapidly shifting the competitive landscape. These emerging technologies create an environment that is connected and open, simple and intelligent, fast and scalable. Organizations must embrace disruptive technologies to drive innovation
Mobile Health at Ochsner: The Apple HealthKit and Epic EMR IntegrationRahlyn Gossen
These slides are from the April 2, 2015 meeting of Health 2.0 New Orleans with special guest Jonathan Wilt, the Assistant Vice President of the Center for Innovation at Ochsner Health System. Jonathan spoke about Ochsner's Health System's integration of Apple HealthKit with the Epic EMR.
Audio is here: http://www.youtube.com/watch?v=UsSKui7m4VY
Virtual health is supporting continuing efforts to further humanize health care by extending and expanding the concept of a patient-centric care delivery model into one that is truly life-centric.
Virtual health uses telecommunication and networked technologies to connect clinicians with patients (and with other clinicians) to remotely deliver health care services and support well-being. For providers, committing to virtual health at a personal and organizational level affords ever-increasing opportunities to deliver the right care at the right time in the right place, in a connected and coordinated manner.
By strengthening and facilitating a therapeutic alliance between clinicians and patients, virtual health is an important step on our continuous journey to humanize health care. It works within and around a patient’s life, as opposed to their sickness, to deliver care when, where, and how they need and want it. Also, virtual health works its way into consumers’ daily routines by being embedded in electronic devices associated with living life (e.g., smartphones and personal computers) more so than caring for sickness.
The healthcare industry is primed for expanded adoption of virtual health; a 2016 report estimated that the US virtual health market will reach $3.5 billion in revenues by 2022. Several factors are elevating stakeholder interest, including expected physician shortages, continued growth in digital technologies, changing reimbursement models, increasing consumer demand, and the evolving regulatory landscape. One game-changer: Today, nine in 10 American adults use the internet, giving clinicians the capability and flexibility to communicate with and serve health care consumers via the web.
Pharma must change the ways it deals with physicians and patients. These three digital health technology companies will revolutionize the way Pharma does business.
Health device makers, to date, have primarily targeted consumers who are either fitness focused or chronically ill. But between these two extremes sits a large, fragmented and often overlooked population who seek better information to effectively manage their health. Our research suggests that successful solution providers will approach this market opportunity as an ecosystem of partners – with an integrated solution that extends beyond the device itself. By plugging the information gap for these consumers, solution providers can help fuel healthcare innovation.
Presentation of Top 10 eHealth & Healthcare trends presented at IDC Content Management Evolution 2014: Portals, Mobile and Social. Madrid (Spain), 11th of March 2014. www.cesaralonso.com
HXR 2016: The Health IoT: Remote Care and Mobile Solutions -Manu Varma, PhilipsHxRefactored
Through new telehealth technologies and increased data analysis physicians are gaining insights into patients like never before, allowing them to facilitate early interventions, improve adherence, and reduce readmission rates -- not to mention at a price more affordable than ever. The companies you’ll hear from in this session are using a healthy and innovative mix of data, educational tools, sensors, and more to improve patient outcomes.
Breakout Session: Cybersecurity in Medical DevicesHealthegy
Presentation by PwC at Medtech Conference 2016.
Participant:
Geoff Fisher, Director – PwC
Powered by:
Healthegy
For more healthcare innovation
Visit us at Healthegy.com
Creating Interoperable Medical Devices that fit into Hospital Enterprise IT E...Shahid Shah
Creating connected medical devices is challenging but doing so in an interoperable manner that can easily and flexibly fit into modern hospital IT environments is even more difficult. This presentation provides sage advice on how to design connected life-critical medical devices so that they work well within modern hospital environments.
An edited version of my presentation at the Mobile Health Workshop for Engineers and PhD scholars at National Institute of Technology Surathkal, Mangalore.
2016 IBM Interconnect - medical devices transformationElizabeth Koumpan
Emerging technologies such as Internet of Things, 3D Printing are driving the creation of new business models and forcing the Industry for transformation. The product centric model where the Industry main objective was to develop the device, is moving to software and services model, with the focus on Big Data & Analytics, Integration and Cloud.
The maturation of technologies such as social, mobile, analytics, cloud, 3D printing, bio- and nanotechnology are rapidly shifting the competitive landscape. These emerging technologies create an environment that is connected and open, simple and intelligent, fast and scalable. Organizations must embrace disruptive technologies to drive innovation
Mobile Health at Ochsner: The Apple HealthKit and Epic EMR IntegrationRahlyn Gossen
These slides are from the April 2, 2015 meeting of Health 2.0 New Orleans with special guest Jonathan Wilt, the Assistant Vice President of the Center for Innovation at Ochsner Health System. Jonathan spoke about Ochsner's Health System's integration of Apple HealthKit with the Epic EMR.
Audio is here: http://www.youtube.com/watch?v=UsSKui7m4VY
Virtual health is supporting continuing efforts to further humanize health care by extending and expanding the concept of a patient-centric care delivery model into one that is truly life-centric.
Virtual health uses telecommunication and networked technologies to connect clinicians with patients (and with other clinicians) to remotely deliver health care services and support well-being. For providers, committing to virtual health at a personal and organizational level affords ever-increasing opportunities to deliver the right care at the right time in the right place, in a connected and coordinated manner.
By strengthening and facilitating a therapeutic alliance between clinicians and patients, virtual health is an important step on our continuous journey to humanize health care. It works within and around a patient’s life, as opposed to their sickness, to deliver care when, where, and how they need and want it. Also, virtual health works its way into consumers’ daily routines by being embedded in electronic devices associated with living life (e.g., smartphones and personal computers) more so than caring for sickness.
The healthcare industry is primed for expanded adoption of virtual health; a 2016 report estimated that the US virtual health market will reach $3.5 billion in revenues by 2022. Several factors are elevating stakeholder interest, including expected physician shortages, continued growth in digital technologies, changing reimbursement models, increasing consumer demand, and the evolving regulatory landscape. One game-changer: Today, nine in 10 American adults use the internet, giving clinicians the capability and flexibility to communicate with and serve health care consumers via the web.
Pharma must change the ways it deals with physicians and patients. These three digital health technology companies will revolutionize the way Pharma does business.
Health device makers, to date, have primarily targeted consumers who are either fitness focused or chronically ill. But between these two extremes sits a large, fragmented and often overlooked population who seek better information to effectively manage their health. Our research suggests that successful solution providers will approach this market opportunity as an ecosystem of partners – with an integrated solution that extends beyond the device itself. By plugging the information gap for these consumers, solution providers can help fuel healthcare innovation.
Presentation of Top 10 eHealth & Healthcare trends presented at IDC Content Management Evolution 2014: Portals, Mobile and Social. Madrid (Spain), 11th of March 2014. www.cesaralonso.com
HXR 2016: The Health IoT: Remote Care and Mobile Solutions -Manu Varma, PhilipsHxRefactored
Through new telehealth technologies and increased data analysis physicians are gaining insights into patients like never before, allowing them to facilitate early interventions, improve adherence, and reduce readmission rates -- not to mention at a price more affordable than ever. The companies you’ll hear from in this session are using a healthy and innovative mix of data, educational tools, sensors, and more to improve patient outcomes.
Breakout Session: Cybersecurity in Medical DevicesHealthegy
Presentation by PwC at Medtech Conference 2016.
Participant:
Geoff Fisher, Director – PwC
Powered by:
Healthegy
For more healthcare innovation
Visit us at Healthegy.com
Creating Interoperable Medical Devices that fit into Hospital Enterprise IT E...Shahid Shah
Creating connected medical devices is challenging but doing so in an interoperable manner that can easily and flexibly fit into modern hospital IT environments is even more difficult. This presentation provides sage advice on how to design connected life-critical medical devices so that they work well within modern hospital environments.
To view recording of this webinar please use the below link:
https://wso2.com/library/webinars/2015/02/connected-health-reference-architecture/
The key focus areas of this session are
Overview of healthcare IT landscape
Standards and protocols widely used in healthcare platforms
SOA is healthcare domain
Quality of services in healthcare platforms
A connected healthcare reference model
The 2016 - 2020 strategy for the Personal Connected Health Alliance defines the field of personal connected health to provide one common definition and reviews the scope of this space, its market insights and more. Utilize this presentation to understand PCHAlliance's vision of personal connected health's strategic role and how we aim in pursuing this potential.
What hope do social networks offer the future of person-centered health? Tune in to see one disruptive woman’s vision for social network- driven wellness, Jen Hyatt, CEO, Big White Wall.
Can a custom Drupal 8 Theme be created in 40 minutes? The results might not be pretty but we're going to create a theme from start to finish. In the process you'll get to see all the components that make up a theme and get acquainted with tools that get the job done.
A presentation showing the conversion of a html+css template to a simple Drupal theme. Theme files can be found at http://groups.drupal.org/node/23694#comment-83107
In this session, we will explore the how the recent explosion of devices has disrupted the process of designing a website that we've crafted over the past decade.
When designers only have one instance of website (i.e., desktop) to design, the layout is uniform. The header, content area, sidebar, and footer all remain static. Furthermore, the elements are relatively uniform as well. Buttons, navigation, typography, and images are all basically the same across across the various pages. But if you are designing a responsive website – one whose look and feel adapts depending whether you're using a phone, laptop, or tablet – then these elements and especially the layout begin to diverge.
After this session, you should leave with the confidence to argue the importance of responsive design to your client or boss – and that the with the proper strategy, the extra effort and costs can be justified (and hopefully minimized).
Minimalist Theming: How to Build a Lean, Mean Drupal 8 ThemeSuzanne Dergacheva
Back in the Drupal 7 days (aka last year), we came across some pretty large, hard-to-maintain Drupal 7 sites. The theme was often responsible for a lot of the cruft. We saw themes with excess code, too many template files, and not enough documentation.
The Drupal 8 theme layer provides new features like libraries and Twig blocks that can help us to build cleaner, better-organized themes. So now is a good time for themers to re-visit which theming techniques to use to create themes that are smaller, maintainable, and well organized.
[Srijan Wednesday Webinars] Drupal 8: Goodbye to 10 Years of Theming HeadachesSrijan Technologies
Drupal 8 has many new and exciting features, but none are as radical and essential as the changes made to the theme system. For over 10 years, Drupal's front end was designed and built by developers who tried their very best to figure out what the front end needed. The lack of dedicated front-enders in core resulted in a less than ideal front end architecture.
In this webinar, our speaker would share how Drupal 8 and Twig have changed it all. He would cover what’s new in Drupal 8 theme system, and how to use Twig to relieve the headache that you, as a themer, have been suffering from.
You can watch the complete webinar recording here: https://youtu.be/PxEpnGI5z6w
IBM Smart Home Vision Using Cloud TechnologyIBMElectronics
There is more to the smart home than installation of smarter devices. In this vision of the smarter home, one that is enabled by cloud technology, partnerships among ecosystem players will be vital.
Creating Layouts and Landing Pages for Drupal 8 - DrupalCon DublinSuzanne Dergacheva
This presentation from DrupalCon Dublin covered site building techniques for creating landing pages and layouts, including using custom blocks, paragraphs, and panels, and then different theming approaches for creating these layouts.
Jake Williams - Navigating the FDA Recommendations on Medical Device Security...centralohioissa
In January, the FDA has draft recommendations for medical device security after the sale. Among other things, the recommendations tell manufacturers how to evaluate security risks, how to build a program for coordinated vulnerability disclosure program, and how to intake vulnerability reports from researchers. While the security of medical devices is especially important given the potential consequences, we can learn from the FDA recommendations regardless of our industry. Any recommendations adopted by the FDA for medical devices are likely to be implemented across other verticals for their IoT devices as well. Whether you manufacture, purchase, integrate, implement, or generally try to run away from IoT devices, there’s plenty to take away from this session while learning about the future of IoT device security.
Med Device Vendors Have Big Opportunities in Health IT Software, Services, an...Shahid Shah
If you’re in the medical device manufacturing or hardware sales business your revenue growth (CAGR) is under pressure like never before. You’re being asked to do more with less but you’re probably going to find that hard to accomplish because of one or more of the following challenges:
* Longer product development timelines caused by more FDA and other government regulations
* Increased demand by customers to have your devices deliver user experiences that are more like “consumer” devices such as cell phones and tablets
* Lower margins as a reaction to commodity competition (your sensor hardware business will be commoditized faster and faster over time)
* More complex and longer sales cycles because devices are now being approved for sale not by facilities and clinical executives alone but increasingly by CIOs and IT teams
* Increased cost of risk management and compliance caused by connectivity requirements
Any one of these challenges is difficult to meet but these days you’re probably being asked to meet more than one simultaneously. The solutions are not simple but the good news is that medical device manufacturers have many revenue generation opportunities today that can fund the new strategic imperatives you’ll need to put into place to meet the challenges listed above.
This briefing, presented by Netspective CEO Shahid Shah, describes some of the opportunities and how device vendors can take advantage of them.
Little documentation and few base themes with 8.x branches - what's a front end developer to do? I'll show you what's changing in Drupal theming between D7 and D8 and how to create a custom theme based on the Classy base theme, step by step. We'll go over Twig basics and Twig debugging.
This whitepaper is written by Pieter Rahusen, Clara Aguilo and Lydia Goerig Market Development
Managers Healthcare, from Ricoh Europe. This document is meant for colleagues, prospects,
customers and relations from Ricoh. This whitepaper shows Ricoh’s vision about a paperless hospital
via digitalization and management of patient/client and company records in healthcare. Ricoh’s vision
is based on years of experience with information processes in European healthcare institutions. It has
led to a modular solution that consists of several building blocks. These blocks guarantee a seamless
integration of several processes. The solution also uses the standards from existing infrastructures and
work methods.
The existing primary business and care applications, the IT environment and the work methods are
therefore the starting point for change management. Ricoh’s healthcare specialists have a broad
understanding and knowledge of the procedures and laws within healthcare. This makes Ricoh
an excellent and reliable partner that can guide and support healthcare organizations with issues
regarding a paperless office.
This whitepaper describes the building blocks of the complete solution for Smart Document
Management from Ricoh. It enables healthcare institutions to gradually switch to a paper less hospital
(step-by-step). The goal of this whitepaper is to offer objective and relevant information that supports
the decision making process about the implementation of a paperless office.
In search of a digital health compass: My data, my decision, our powerchronaki
Knowledge is power. Despite extensive investments in digital health technology, navigating the health system online is challenging for most citizens. Also for eHealth, the “Inverse Care Law” proposed by Hart in 1971, seems to apply. Availability of good medical or social care services and tools online, varies inversely with the need of the population. The low adoption of eHealth services, and persistent disparities in health triggers a call for multidisciplinary action.
Barriers and challenges are not to be underestimated. Culture, education, skills, costs, perceptions of power and role, are essential for multidisciplinary action. This comes together in digital health literacy, which ought to become an integral part to navigate any health system. Patients living with an implanted device or coping with persistent, chronic disease such as diabetes, as well as citizens engaged in self-care, caring for an elderly relative, a neighbor, or their child with illness or deteriorating health, need a digital health compass.
The panel will engage the audience to elaborate on a vision for this personal, digital health compass and drive advancement in health informatics and digital health standards. The transformative power of health data fueled by targeted digital health literacy interventions can be leveraged by open, massive, and individualized delivery. This way, digital health literate, confident patients and citizens join health professionals, researchers and policy makers to address age-related health and wellness changes to shape the emerging precision medicine and population health initiatives.
From a panel in the eHealthweek 2016. http://www.ehealthweek.org/ehome/128630/hl7-efmi-sessions/
Using technology-enabled social prescriptions to disrupt healthcareDr Sven Jungmann
As chronic diseases are increasingly straining healthcare systems, social factors are gaining importance. Since the birth of social medicine (19th century), we saw many failed attempts to beat the dominance of the biomedical model. Social prescriptions have come, raising hopes that non-biomedical solutions will improve outcomes and optimise resource use. Social Prescriptions connect citizens to support to address social determinants of health and encourage self-care for physical and mental health. Social prescriptions can make us healthier cheaper and with fewer side effects than most drugs. Social prescriptions can become a disruptive force as they can be personalised, improve lifestyle-related diseases, and support non-biomedical issues affected by social determinants of health.
20 tendencias digitales en salud digital_ The Medical FuturistRichard Canabate
Resaltado de las tendencias que darán forma a la atención médica post COVID19.
No se trata de enumerar estas tendencias, sino de dar una valiosa visión de los factores de conducción detrás de ellas mientras que es muy específico. Se trata de mostrar cuáles son las áreas exactas que deben destacarse entre todas las áreas en el tema "IA en la atención médica", por ejemplo.
Healthcare as an industry is transforming. The concept of wellbeing is increasing in importance. Living environments are evolving, including smart homes, assisted living and robotics. Technologies and innovations are having major impacts to individual’s life. Individuals are taking more control and recognizing also their responsibility.
Business Finland and Future Watch commissioned a study on the landscape of developments that will impact the delivery of Health & Wellbeing, to better understand the anticipated transformations, impacts and opportunities to support its strategy for ensuring Finland is well positioned to take advantage of such trends and to help drive better decision making for all stakeholders in Finland. Results of the study are published and discussed with stakeholders and companies in Business Finland’s Smart Life Finland program webinars.
با گسترش فناوری اطلاعات و سرویس های مختلفی امروزه در زندگی انسان ها ارائه می شود حوزه سلامت و درمان هم بی بهره از این گسترش فناوری نبوده و در صورتی که سیاستمداران و برنامه ریزان کشور بتوانند از ظرفیت های ترکیب دانش پزشکی و فناوری اطلاعات بهره ببرند شاید با وجود افزایش جمعیت کهنسال و نیاز به رسیدگی های خاصی که در این قشر احساس می شود بتوان در کاهش هزینه های درمان گامی برداشت
mHealth Israel_GEARING COMMUNICATIONS TO RAISE CAPITAL AND ATTRACT CUSTOMERS_...Levi Shapiro
Presentation by Gil Bashe, Managing Director, Healthcare Practice, Finn Partners: "GEARING COMMUNICATIONS TO RAISE CAPITAL AND ATTRACT CUSTOMERS- FROM PLAN TO PARTNERS TO PATIENTS". Includes tips to avoid failure by embracing complexity, description of the Health Ecosystem Landscape, developing a plan to impact care, cost and outcomes, overview of the US Payer market, and top digital health influencers.
The 2023 Digital Health Barometer_compressed.pdfJordiCarreras13
Data interoperability requires the adoption and
implementation of common and (ideally) open
standards. Lack of interoperability limits the
re-use of data between healthcare organisations
within a country and across borders. The rise of
cloud platforms and mobile technology further
complicates the data environment. “Data gets
captured and it is quite complex and hard to
share,” says David Hansen, CEO of the Australian
e-Health Research Centre, CSIRO. “When shared,
it is often not computable. Human intervention
is needed to do analytics and this is really
expensive.”
All countries except Spain achieve the highest
score on this indicator, demonstrating that
digital health and health information industrybased
technical standards for data exchange,
transmission, messaging, security, privacy and
hardware are in use in the majority of applications
and systems to ensure the availability of highquality
data.
Digital health literacy and internet connectivity
are ‘super’ social determinants of health, as
they have the power to affect the wider social
determinants of health.17 Although the use of
digital tools – such as apps, patient portals, and
monitoring devices – provides better support
beyond clinical settings, greater reliance on them
can increase the disparity between people with
digital access and skills and those without, and (by
extension) health disparities.18 “One of the major
concerns globally in digital health has been tech
equity,” says Majmudar. “The digital divide could
worsen. You need access to the internet, tools
and resources. Every country should focus on
connectivity, including the US. Can people afford
the data plans they need to access telemedicine
and remote care? Do we have connectivity in
every area, urban or rural?”
Similar to What is personal connected health? (20)
We are truly on the edge of a new and exciting era. Here are the top five ways AI is revolutionizing healthcare and what could be in store over the coming years.
Can new technologies like artificial intelligence, wearables and digital therapeutics transform healthcare? Rapid changes in new technology show promise to move healthcare forward and improve efficiency.
Ipsos Healthcare executed a study on the future of connected health in the areas of patient-generated health data, security and the role of connected health in care outcomes.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
2. Wikipedia: “Connected health is a model for healthcare delivery that uses
technology to provide healthcare remotely. Connected health aims to maximize
healthcare resources and provide increased, flexible opportunities for consumers to
engage with clinicians and better self-manage their care. It uses technology – often
leveraging readily available consumer technologies – to deliver patient care outside
of the hospital or doctor's office.”
Accenture: “Connected health is an approach to healthcare delivery that leverages
the systematic application of healthcare information technology to facilitate the
accessing and sharing of information, as well as to allow subsequent analysis of
health data across healthcare systems. “…The ambition of connected health is to
connect all parts of a healthcare delivery system, seamlessly, through interoperable
health information processes and technologies so that critical health information is
available when and where it is needed.”
First Things First: The Need to Define the Field
2
Many working
definitions assume that
users of personal
connected health are
“patients” who are
already in a healthcare
system—as opposed to
individuals attempting
to remain, or to
become healthy.
3. Let’s break down the terms:
Personal: unique to a specific person – different for every
individual, customized, bespoke.
Connected: individuals’ information flows seamlessly, with their
consent, to and from a clinician, caregiver, or community.
Health: the state of a person’s physical, social, and mental well-
being, including but not limited to the absence or control of a
disease.
3
Arriving at a Common Definition
The Personal
Connected
Health Alliance
(PCHA) has an
opportunity to
define what
personal
connected
health is.
4. 4
The Scope of the “Personal Connected Health” Space
After identifying
the different
terms and
conducting
market analysis,
we arrived at
these
boundaries for
the personal
connected
health space.
5. Different sources reach
consensus on >30%
Compounded Annual
Growth Rate (CAGR); health
and wellness main source
of growth:
5
Market size, growth, and segmentation
Sources: TechNavio - Global Connected Health M2M Market 2015-2019 Size and Forecast, Overview, share, Demand, Technology, Services,
Segmentation, Market research report; Markets and Markets: “mHealth Solutions Market Connected Devices, AppS, Services - Global Forecast
to 2020”; Tractica – Home Health Technologies; CEA white paper - connected health and wellness market; WHO global status report on
noncommunicable diseases; Mhealth knowledge - Using mobile technologies for healthier ageing; PWC - The global mhealth market
opportunity and sustainable reimbursement models
Mobile health market
by geography
Latin America 7%
Africa 5%
North
America
28%
Asia
30%
Europe
30%
Mobile health market
by submarket (2017)
Wellness & Prevention 7%
Treatment 10%
Diagnostic
Services
15%
Independent
Ageing
22%
Chronic Disease
Management
46%
● Estimates converge on global market
size between $50-$60bn in 2020
● Health and wellness has highest
CAGR (48.1%) in the mobile market
● 78.5 million consumers using home
health technologies by 2020
● Split between chronic diseases
depends on geography: China more
cardiovascular, US more obesity
6. In remote patient monitoring, there are a number of opportunities and barriers:
● In the US, lack of an economic model with aligned incentives through reimbursement,
as well as concerns about liability for prescribing devices and analyzing incoming data.
● Scientific evidence and ‘portable’ models for remote monitoring still developing.
● Worldwide, 4.9 million people are remotely monitored.
In consumer health, there are more opportunities than barriers to growth. The main
challenge is of consistent usage for health purposes over fashion purposes rather than
adoption.
● 50% of owners of fitness trackers stop using their device within 6 months.
● Clinicians are wary of patient-generated data from consumer grade devices.
● Potential opportunity for PCHA in directing the inevitable growth of wearables, Internet
of Things, “quantified self” towards consumers taking charge of their health.
6
Key qualitative insights to two primary sub-markets
Sources: Key Stakeholder Interviews;
Economist Intelligence Unit – How
technology is transforming healthcare;
ATKearney - “Mobile Health: Mirage or
Growth Opportunity”; PWC: The global
mhealth market opportunity
The opportunities
and barriers to
growth in each sub-
market are different
and require tailored
approaches.
7. 1. Lack of awareness and understanding of full potential of personal
connected health on all sides: public, providers, policymakers, industry,
patients. No common definition or language exists for personal
connected health.
2. Poorly defined market creates an “application gap” between what the
real needs are, and what the technology market is currently doing.
3. Not enough thought leadership and a “research gap” enables these
problems to continue.
4. Lack of coordination and collaboration across diverse groups of
stakeholders contributes to all of the above.
5. Lack of widely accepted framework for behavioral change, and
measuring personal connected health outcomes exacerbates the
problem.
7
Overarching Nature of the Problem
Each stakeholder
group only sees
their little piece,
not the full picture.
Consequently,
there is a poor
match between
health needs and
innovation.
8. 8
Key Barriers & Obstacles
The market
for Personal
Connected
Health is
characterized
by misaligned
incentives,
concerns,
and silos.
Misaligned Incentives Concerns Silos
● Competing priorities
● Lack of clarity on
reimbursements and
viable economic
models
● Healthcare community
skepticism (liability,
workflow, confidence,
reimbursement)
● Privacy concerns
● Disconnected data silos, especially with regard
to Employee Health Records versus patient-
collected data and consumer experience of
health in daily life
● Technologies are not designed to address the
experience of individuals outside and within
health system
● Research is not integrated across the continuum
of behavioral health and care or fast enough to
keep up with the pace of innovation
Drivers and Root Causes
● Prevention, public
health not valued
● Disengagement of
individuals from
behavioral causes of
poor health
● Economic models do
not keep pace with
technology
● Lack of processes or
mechanisms to address
concerns systematically
● Regulation does not keep
pace with innovation
● Lack of coordination between diverse players
● Lack of interoperability between technology
platforms and systems
9. 9
Assets & Opportunities
PCHA will leverage
current market
opportunities and
the unique assets
that it brings to
establish itself as
the driving force
behind the personal
connected health
movement.
Internal PCHA Assets External Opportunities
● Critical mass of key relationships from
which to build
● Resources
● Team
● HIMSS
● Global reach and footprint
● Continua guidelines
● Continua certification
● Convening venues that are established
and known
● Consumerization of health
● Rapid uptake and proliferation of
personal connected health devices
● New investors and new entrants in the
market
● Renewed focus on personal,
community, and public health
● Increasingly tech-savvy 50+ generation
● Good models emerging for
interoperable personal connected
health in Scandinavia
● Market hungry for leadership
10. IF we support thought leadership, facilitate coordination and collaboration
in innovation and research, and increase awareness and understanding on
the part of all stakeholders…
THEN we will address the “app and research gaps,” increase the adoption
and long-term use of personal connected health devices, maximize
customized individual and population-specific health promotion...
THAT contributes to a world in which personal responsibility for health and
positive behavior change is the norm and improved health outcomes
through technology is a reality.
10
PCHA’s Proposed “Theory of Change”
11. Vision: Better health and well-being for all through increased personal
responsibility and connectivity as well as improved care delivery
enabled by technology.
Mission: The Personal Connected Health Alliance responds to
individual, community, and public health needs by catalyzing market
and policy innovation, research, and collective action for sustained
adoption of personal connected health.
11
Proposed Vision & Mission
12. 12
Overall Approach and Resulting Strategic Roles
The link between the nature of
the problem, and what we
propose to do about it, lies in
addressing the overarching
factors that contribute to the
current state of affairs (the lack
of: thought leadership;
coordination and collaboration;
and, awareness and
understanding of full personal
connected health potential on all
sides) through five strategic
roles. They are the critical
ingredients for bringing about
broad-based change.
Thought
Leadership
Thought
Leadership
Convening
Role
Galvanising
Collective Action
Policy &
Advocacy
Raising the Bar &
Monitoring Progress
Coordination &
Collaboration
Awareness &
Understanding
13. Approach Strategic Roles Desired Outcomes & Outputs
Thought
Leadership
Coordination &
Collaboration
Awareness &
Understanding
Thought leadership
● The field of personal connected health is well
established
● Key research and health associations are driving
the personal connected health agenda forward
● An evidence base is built
● A robust library of publications is produced
● Key media outlets are actively engaged on
personal connected health issues
● Continua is a trusted voice for ensuring that
competing technology standards are arbitrated in
favor of the security, privacy and quality
necessary for improved health
● Product development is increasingly aligned with
health needs
● A theoretical framework for sustained behavior
change is established and adopted
Convening role
Galvanising collective action
Policy & advocacy
Raising the bar & monitoring progress
13
Strategic Role #1: Thought Leadership
14. Approach Strategic Roles Desired Outcomes & Outputs
Thought
Leadership
Coordination &
Collaboration
Awareness &
Understanding
Thought leadership
● PCHA is the go-to convener, collaborator and
coordinator between government, different
private industries and consumers who need to
collaborate to maximize the impact of personal
connected health
● Strong public-private partnerships are formed
● The research agenda and innovation pipeline are
effectively facilitated
● The voices of individuals and their caregivers are
increasingly appreciated
● Industry consensus on best practices for health-
related connectivity is achieved
● Personal connected health is mainstreamed into
both the health and technology fields
Convening
Galvanising collective action
Policy & advocacy
Raising the bar & monitoring progress
Strategic Role #2: Convening
14
15. Approach Strategic Roles Desired Outcomes & Outputs
Thought
Leadership
Coordination &
Collaboration
Awareness &
Understanding
Thought leadership
● Robust, rapid research community or
“accelerator” pursuing thought leadership
strategy
● The focus of technology community on public
and community health needs (e.g. aging)
increases
● Support for policy innovation and reform expands
● Acceptance of Continua’s open source
framework as the industry standard for health-
related connectivity grows
● Health outcomes-based business models are
established
● Doctors seamlessly receive and use data
generated by individuals
● People are motivated to take better care of
themselves through technology
Convening role
Galvanising collective action
Policy & advocacy
Raising the bar & monitoring progress
15
Strategic Role #3: Galvanising Collective Action
16. Approach Strategic Roles Desired Outcomes & Outputs
Thought
Leadership
Coordination &
Collaboration
Awareness &
Understanding
Thought leadership
● The number of policies supportive of personal
connected health increases
● Health literacy and numeracy improves as
individuals understand how to use their own data
generated by personal connected health
technologies
● Incentives for long-lasting adoption of personal
connected health technologies are recognized
● The value placed on, and demand for, data
sharing and interoperability grows
● The number of certified devices increases
● More countries adopting Continua standards at
the national level
Convening role
Galvanising collective action
Policy & advocacy
Raising the bar & monitoring progress
16
Strategic Role #4: Policy & Advocacy
17. Approach Strategic Roles Desired Outcomes & Outputs
Thought
Leadership
Coordination &
Collaboration
Awareness &
Understanding
Thought leadership
● Personal connected health innovation market
better matches the health needs of individual’s
and their caregivers
● Industry has the information it needs to more
closely align product development and
distribution with individual needs
● Adoption of personal connected devices grows
● Level of personal ownership over health
increases
Convening role
Galvanising collective action
Policy & advocacy
Raising the bar & monitoring progress
17
Strategic Role #5: Raising the Bar & Monitoring Progress
18. Year One Activities
Thought Leadership Activities
In this role, PCHA will
develop a thought
leadership strategy to
identify key health
needs where personal
connected health
already is—or could
be—making a world of
difference.
● Personal connected health definition and
Wikipedia page
● Thought Leadership Strategy examines one
topic in the first year (such as Ageing) and lays
the foundation for subsequent work over the
next four years to establish PCHA as a trusted
source of value demonstration given rapidly
changing technology.
● Publication series (3-4 per year) such as: “The
State of Personal Connected Health” report; a
“Ten Year Look Back to Look Ahead” of
standards and interoperability; and a
publication to come out of collaborative
thought leadership strategy such as
“Opportunities for Personal Connected Health
and Ageing.”
Year Two Activities
● Assess state of personal
connected health and thought
leadership priorities to keep
pace with rapidly changing
field
● Framework models for
innovation pipeline linked to
health needs engagement.
● Framework models for
behavior change linked to
personal connected health
devices.
18
19. In this role, PCHA will
convene gatherings
and participate in
events that help to
set the agenda and
advance learning,
best practices and
education in the field.
19
Convening Activities
Active participation and engagement in
health and technology events to
advance personal connected health
field, such as:
● Aging 2.0
● AARP meetings
● One or two of the following: CES,
SxSW, Aspen Institute, and Mobile
World Congress
● Wireless Health Research
conferences
Convening large, medium, and small
gatherings related to personal connected
health, including:
● Connected Health Conference in
Washington, DC - December 11-13,
2016
● Personal Connected Health content at
HIMSS17
● African Digital Health Summit with
HealthEnabled
● 2-3 Continua member working group
meetings (in Europe, Asia and
Washington, DC)
● Collaborative technology creation
events convened by Continua (such as
Plugfests, Connectathons)
20. Galvanizing Collective Action
20
Year One Activities
Year-long collaborations to promote the adoption and effective use of personal
connected health devices by individuals and providers will further reinforce
PCHA’s thought leadership and advocacy roles.
● Develop framework for collective action
related to personal connected health and
launch two initiatives at the Connected
Health Summit in Dec 2016: Country
Adoption of Continua Guidelines and
Aging.
● Begin to implement the framework for
action and cultivate new initiatives.
Year Two Activities
● Initiate a program related to
one or two health issues for
which the Continua standards
are already and can further
make an important
contribution to improved health
outcomes (i.e. hypertension,
diabetes, congestive heart
failure, etc.)
In this role, PCHA
will galvanize
collective action
around innovation
and research
linked to prioritized
health needs.
21. Policy & Advocacy Activities
In this role, PCHA
will provide the
information, and
produce the
increased
awareness, on the
part of all
stakeholders, that is
necessary to bring
about real change.
21
Public Policy
● Collaborating with advocacy groups and
policy makers to proactively overcome
barriers to adoption and address risks
and concerns.
● Align existing US and European policy
advocacy working groups with updated
PCHA strategy, maintaining
interoperability focus in first year,
expanding into additional issues
thereafter.
● Collaboratively develop an overarching
media strategy with HIMSS Media.
Public Education
● Social media campaigns and public
awareness to engage consumers in
more effective use of technology to
promote better health: Prioritize one
(TBD) activity in this area that aligns
with our year-long collaboration topic
(e.g., aging.)
● Creation of strategy and content to
educate public and key stakeholders
on benefits and risks related to
personal connected health: Prioritize
one (TBD) activity in this area.
22. Year One Activities Ongoing Analysis
● Annual report on the state of
connected health technology
adoption around the world,
celebrating progress, and
identifying opportunities to
accelerate adoption.
● Work with HIMSS Analytics to
collaboratively design a market
analysis platform in Year One.
● Begin implementation in Year Two.
● “Consumer Reports” for personal
connected health: explore partnership
opportunities with Consumer Reports.
● Survey on personal ownership over
health and role of technology: explore
partnership opportunities with Pew.
● Explore other partnerships that could
increase collective understanding of
“the individual” and their needs in
addition to the industry and its needs.
● Expand Continua certification levels
and activities.
In this role, PCHA will
collaboratively
develop resources and
frameworks to help
monitor and measure
progress in the
personal connected
health field, raising the
bar for all.
22
Raising the Bar & Monitoring Progress