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The most common symptom of gout is pain that is very severe. The affected area is going to be red, tender, and swollen. These are the physical signs that gout may be developing in that area of the body.
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There are two different styles of treatment that you want to look at. The first is prevention and the other is taking care of it at the first sign so that it isn’t full blown and become painful.
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Not only does gout toe look terrible, it is very painful. The redness and throbbing can last for days. The pain is excruciating.
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The most common first time gout-symptoms are inflammation and pain in the big toe joint of one foot.
Note that the big toe is not the only joint that can be affected by gout symptoms. Pain can appear in many joints, including fingers, wrists, elbows, knees, ankles and feet.
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Ankle gout involves that part of the body swelling up and becoming very painful. It typically will affect the ankle joint bones, tendons and ligaments and that makes it very hard to walk
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The foot can swell up dramatically when someone has gout. The pain associated with gout is unbelievable and many people say it feels like someone is burning them with a hot fireplace poker.
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There are two different styles of treatment that you want to look at. The first is prevention and the other is taking care of it at the first sign so that it isn’t full blown and become painful.
http://curegoutpainnow.com
Not only does gout toe look terrible, it is very painful. The redness and throbbing can last for days. The pain is excruciating.
http://curegoutpainnow.com
The most common first time gout-symptoms are inflammation and pain in the big toe joint of one foot.
Note that the big toe is not the only joint that can be affected by gout symptoms. Pain can appear in many joints, including fingers, wrists, elbows, knees, ankles and feet.
http://curegoutpainnow.com
Ankle gout involves that part of the body swelling up and becoming very painful. It typically will affect the ankle joint bones, tendons and ligaments and that makes it very hard to walk
http://curegoutpainnow.com
The foot can swell up dramatically when someone has gout. The pain associated with gout is unbelievable and many people say it feels like someone is burning them with a hot fireplace poker.
http://curegoutpainnow.com
What causes gout? In the majority of cases the answer to this question is quite simple. An excess of uric acid in your body.
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Gout occurs when uric acid crystals form in the joint areas.This is a form of arthritis and it can affect people when they are very young.
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The pain during an attack of gout is caused by the deposit of urate crystals. While gout pain will often show up in the big toe area, this is not the only place that it can be found.
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When a person has acute gout, they will have sudden pain that develops in one of their joints. This typically in the elbow, the big toe, or the ankle but gout can attack any of the joints in the body.
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There are many different gout remedies available to the gout patient. The one you choose will depend on your doctor’s advice and also your own preferences.
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In order to successfully treat gout and move on with your life you need to be able to find ways to reduce that amount of acid.
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To prevent gout you are going to have to be realistic about your lifestyle. Healthy eating is the best method of prevention.
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There is no cure for gout that a doctor or other professional can offer you. They will typically try to help a person reduce uric acid and control pain.
Who does have believed that merely using various herbs as well as spices in order to flavor as well as enhance your own foods you are able to boost the vitamins and minerals of meals and obtain amazing many benefits as nicely? For more info visit now: http://www.healthwithherbs.org
Tips for Living with Rheumatoid Arthritismanoj singh
Living with rheumatoid arthritis can be made easier, by changing your lifestyle. It simply means to prevent the disease from worsening, by taking proper diet and medication and staying active, as well as having plenty of rest.
Do you really want fat free belly and permanent weight loss solution -KashifaParveen1
It’s natural for anyone trying to lose weight to want to lose it very quickly. But people who lose weight gradually and steadily (about 1 to 2 pounds per week) are more successful at keeping weight off. Healthy weight loss isn’t just about a “diet” or “program”. It’s about an ongoing lifestyle that includes long-term changes in daily eating and exercise habits.
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Many people don’t realize that gout is a type of arthritis. It causes the joint tissue to swell and that puts pressure in that area causing pain.
http://curegoutpainnow.com
What causes gout? In the majority of cases the answer to this question is quite simple. An excess of uric acid in your body.
http://curegoutpainnow.com
Gout occurs when uric acid crystals form in the joint areas.This is a form of arthritis and it can affect people when they are very young.
http://curegoutpainnow.com
The pain during an attack of gout is caused by the deposit of urate crystals. While gout pain will often show up in the big toe area, this is not the only place that it can be found.
http://curegoutpainnow.com
When a person has acute gout, they will have sudden pain that develops in one of their joints. This typically in the elbow, the big toe, or the ankle but gout can attack any of the joints in the body.
http://curegoutpainnow.com
There are many different gout remedies available to the gout patient. The one you choose will depend on your doctor’s advice and also your own preferences.
http://curegoutpainnow.com
In order to successfully treat gout and move on with your life you need to be able to find ways to reduce that amount of acid.
http://curegoutpainnow.com
To prevent gout you are going to have to be realistic about your lifestyle. Healthy eating is the best method of prevention.
http://curegoutpainnow.com
There is no cure for gout that a doctor or other professional can offer you. They will typically try to help a person reduce uric acid and control pain.
Who does have believed that merely using various herbs as well as spices in order to flavor as well as enhance your own foods you are able to boost the vitamins and minerals of meals and obtain amazing many benefits as nicely? For more info visit now: http://www.healthwithherbs.org
Tips for Living with Rheumatoid Arthritismanoj singh
Living with rheumatoid arthritis can be made easier, by changing your lifestyle. It simply means to prevent the disease from worsening, by taking proper diet and medication and staying active, as well as having plenty of rest.
Do you really want fat free belly and permanent weight loss solution -KashifaParveen1
It’s natural for anyone trying to lose weight to want to lose it very quickly. But people who lose weight gradually and steadily (about 1 to 2 pounds per week) are more successful at keeping weight off. Healthy weight loss isn’t just about a “diet” or “program”. It’s about an ongoing lifestyle that includes long-term changes in daily eating and exercise habits.
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Many people don’t realize that gout is a type of arthritis. It causes the joint tissue to swell and that puts pressure in that area causing pain.
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Caused by high levels of uric acid in the blood this disorder causes incredibly painful joints, often starting with the big toe then spreading to other joints.
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Gout is caused by hyperuricemia. This high concentration leads to the formation of urate crystals, as a result the joints become inflamed and stiff, which causes significant pain.
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There are many different gout remedies available to the gout patient. The one you choose will depend on your doctor’s advice and also your own preferences.
What are the signs of gout? Gout is a painful condition, often affecting the toes, but it can affect many other joints as well. If left alone it can get worse, turn into a chronic problem and even cause permanent damage
Losing weight can be dangerous. 10 Possible Reasons for Weight Losssohail
Losing weight can be dangerous. 10 Possible Reasons for Weight Loss
Check if you need to see a doctor.
The word “weight loss”, similar to “fat burning” and many other similar terms that imply weight loss (usually due to the fat component), is usually associated with something useful, healthy, correct and necessary for everyone and everyone.
http://curegoutpainnow.com - Gout is a painful condition, often affecting the toes, but it can affect many other joints as well. If left alone it can get worse, turn into a chronic problem and even cause permanent damage. Gout and uric acid levels in the body are inextricably intertwined as the uric acid leads to the gout problems
http://curegoutpainnow.com - Gout is a painful condition, often affecting the toes, but it can affect many other joints as well. If left alone it can get worse, turn into a chronic problem and even cause permanent damage. Gout sufferers need to realise that there may also be other underlying health problems
Isadiet Plus is a food supplement for diarrhea treatment, constipation treatment, piles treatment, gastric disorder treatment. Ispaghula husk present in Isadiet Plus is the best form of fiber that regulates water absorption in the intestine in small intestine & large intestine thereby allowing the stool to pass easily. Isadiet Plus is prepared with Lactitol Monohydrate with Ispaghula husk granules.
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There are plenty of delicious tasting gout recipes that you will be able to try. By eating right you will be taking assertive action towards reducing your chances of problems with gout in the future.
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Finding gout relief fast is very important. Try to consume lots of fresh berries as they can work very fast to help neutralize the uric acid in the body.
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Uric acid crystals are the underlying problem causing gout pain and inflammation. When there is too much uric acid being produced in the body some of it will form hard microscopic crystals which build up in joint areas.
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The best long term results are obtained by eating a properly planned uric acid diet. Any diet plan that is prescribed for gout patients must be able to reduce the level of uric acid in the blood.
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If you eat too many purines, you may find that you have increased uric acid levels. The body only needs so many purines to function
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Gout is a form of arthritis, usually first characterised in an acute attack in the joint of the big toe.
Gout generally affects middle-aged and overweight men, but can affect other people too.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
2. Understanding gout symptoms and causes is very important. When you know what to look for you can take early action to counter an attack.
3. This means your gout problems can be reduced instead of allowing them to escalate to full blown pain and swelling that will last for more than a week.
4. You don’t want to get into a constant cycle with gout though.
5. This is why you need to learn the underlying causes of gout. By doing so you can take control over your future with it.
6. You won’t feel like you are just at the mercy of trying to get through it when a gout attack occurs. The most common symptom of gout is pain that is very severe.
7. The affected area is going to be red, tender, and swollen. These are the physical signs that gout may be developing in that area of the body.
8. For many people the pain is very different than anything else they have ever experienced in their life.
9. The gout problems may be associated with a fever but it isn’t always going to be one of the symptoms that a person experiences.
10. A diet that is high purine is often associated with causing gout. This type of diet results in the body producing too much uric acid.
11. Then it isn’t properly being flushed out of the body. Hard crystals of the acid forms in various joints of the body.
12. The crystals are very sharp and that is why there is so much pain associated with gout. The body eliminates uric acid when urinating.
13. Some people have jobs where they have trained their bodies to last for many hours without stopping to urinate.
14. This includes those working in factories, offices, and even truck drivers. The problem though is that this can allow high levels of uric acid to develop in the body.
15. Individuals with kidney problems can also be at a high risk for gout. This is because the body isn’t filtering out the uric acid and other elements from the body like it needs to.
16. Studies show that people with high blood pressure are also at risk. The continually use of diuretics can also cause someone to develop gout symptoms and problems.
17. If you have a family history of gout then you are at a high risk of it occurring too. It affects both men and women.
18. This type of arthritis can also start at an early age. Eating right, staying at a healthy weight, and getting exercise daily will help to reduce that genetic risk that may be present.
19. Studies show that alcoholics are more likely to have it too. This is one of the gout symptoms and causes that are often overlooked.
20. There are many health problems associated with heavy drinking. Today there are various in-house and out-patient programs that can assist with making changes to that type of lifestyle.
21. The gout symptoms and causes can be very different from one person to the next. That is why you need to have a good idea of what could occur.
22. You also need to pay attention to your own body and how it reacts
23. For example you may find that gout is most likely to occur when you aren’t eating right. Once you know the situation though you can aggressively pursue natural means of ending it.