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Ankle gout involves that part of the body swelling up and becoming very painful. It typically will affect the ankle joint bones, tendons and ligaments and that makes it very hard to walk
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The foot can swell up dramatically when someone has gout. The pain associated with gout is unbelievable and many people say it feels like someone is burning them with a hot fireplace poker.
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The most common symptom of gout is pain that is very severe. The affected area is going to be red, tender, and swollen. These are the physical signs that gout may be developing in that area of the body.
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Not only does gout toe look terrible, it is very painful. The redness and throbbing can last for days. The pain is excruciating.
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There are two different styles of treatment that you want to look at. The first is prevention and the other is taking care of it at the first sign so that it isn’t full blown and become painful.
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The most common first time gout-symptoms are inflammation and pain in the big toe joint of one foot.
Note that the big toe is not the only joint that can be affected by gout symptoms. Pain can appear in many joints, including fingers, wrists, elbows, knees, ankles and feet.
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The foot can swell up dramatically when someone has gout. The pain associated with gout is unbelievable and many people say it feels like someone is burning them with a hot fireplace poker.
http://curegoutpainnow.com
The most common symptom of gout is pain that is very severe. The affected area is going to be red, tender, and swollen. These are the physical signs that gout may be developing in that area of the body.
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Not only does gout toe look terrible, it is very painful. The redness and throbbing can last for days. The pain is excruciating.
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There are two different styles of treatment that you want to look at. The first is prevention and the other is taking care of it at the first sign so that it isn’t full blown and become painful.
http://curegoutpainnow.com
The most common first time gout-symptoms are inflammation and pain in the big toe joint of one foot.
Note that the big toe is not the only joint that can be affected by gout symptoms. Pain can appear in many joints, including fingers, wrists, elbows, knees, ankles and feet.
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When a person has acute gout, they will have sudden pain that develops in one of their joints. This typically in the elbow, the big toe, or the ankle but gout can attack any of the joints in the body.
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Gout occurs when uric acid crystals form in the joint areas.This is a form of arthritis and it can affect people when they are very young.
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What causes gout? In the majority of cases the answer to this question is quite simple. An excess of uric acid in your body.
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The pain during an attack of gout is caused by the deposit of urate crystals. While gout pain will often show up in the big toe area, this is not the only place that it can be found.
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There are many different gout remedies available to the gout patient. The one you choose will depend on your doctor’s advice and also your own preferences.
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In order to successfully treat gout and move on with your life you need to be able to find ways to reduce that amount of acid.
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There is no cure for gout that a doctor or other professional can offer you. They will typically try to help a person reduce uric acid and control pain.
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To prevent gout you are going to have to be realistic about your lifestyle. Healthy eating is the best method of prevention.
Tips for Living with Rheumatoid Arthritismanoj singh
Living with rheumatoid arthritis can be made easier, by changing your lifestyle. It simply means to prevent the disease from worsening, by taking proper diet and medication and staying active, as well as having plenty of rest.
Residing A Complete Lifestyle With Diabetic issues Sicknesshobert86dan
Experiencing diabetic issues can be tough for many. When people are initially diagnosed with diabetes mellitus, they generally turn out to be scared and they are uncertain the actual way it will have an effect on their existence. With enough time, knowing, and knowledge, managing diabetes mellitus can be easier. When you are coping with diabetic issues and want it to be much less tough, then follow the ideas in this post.
Going Gluten-Free: Celiac Disease vs. Gluten SensitivityAli Ghahary
Before you decide to go gluten-free as part of your dietary plan, it is important to know about the common misconceptions that surround gluten-free diets, in addition to the great benefits.
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Caused by high levels of uric acid in the blood this disorder causes incredibly painful joints, often starting with the big toe then spreading to other joints.
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When a person has acute gout, they will have sudden pain that develops in one of their joints. This typically in the elbow, the big toe, or the ankle but gout can attack any of the joints in the body.
http://curegoutpainnow.com
Gout occurs when uric acid crystals form in the joint areas.This is a form of arthritis and it can affect people when they are very young.
http://curegoutpainnow.com
What causes gout? In the majority of cases the answer to this question is quite simple. An excess of uric acid in your body.
http://curegoutpainnow.com
The pain during an attack of gout is caused by the deposit of urate crystals. While gout pain will often show up in the big toe area, this is not the only place that it can be found.
http://curegoutpainnow.com
There are many different gout remedies available to the gout patient. The one you choose will depend on your doctor’s advice and also your own preferences.
http://curegoutpainnow.com
In order to successfully treat gout and move on with your life you need to be able to find ways to reduce that amount of acid.
http://curegoutpainnow.com
There is no cure for gout that a doctor or other professional can offer you. They will typically try to help a person reduce uric acid and control pain.
http://curegoutpainnow.com
To prevent gout you are going to have to be realistic about your lifestyle. Healthy eating is the best method of prevention.
Tips for Living with Rheumatoid Arthritismanoj singh
Living with rheumatoid arthritis can be made easier, by changing your lifestyle. It simply means to prevent the disease from worsening, by taking proper diet and medication and staying active, as well as having plenty of rest.
Residing A Complete Lifestyle With Diabetic issues Sicknesshobert86dan
Experiencing diabetic issues can be tough for many. When people are initially diagnosed with diabetes mellitus, they generally turn out to be scared and they are uncertain the actual way it will have an effect on their existence. With enough time, knowing, and knowledge, managing diabetes mellitus can be easier. When you are coping with diabetic issues and want it to be much less tough, then follow the ideas in this post.
Going Gluten-Free: Celiac Disease vs. Gluten SensitivityAli Ghahary
Before you decide to go gluten-free as part of your dietary plan, it is important to know about the common misconceptions that surround gluten-free diets, in addition to the great benefits.
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Caused by high levels of uric acid in the blood this disorder causes incredibly painful joints, often starting with the big toe then spreading to other joints.
Ibuprofen overdose occurs when someone accidentally or intentionally takes more than the normal or recommended amount of this medication. See also: Pain ...http://www.ibuprofen200mg.com
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There are many different gout remedies available to the gout patient. The one you choose will depend on your doctor’s advice and also your own preferences.
http://curegoutpainnow.com - Gout is a painful condition, often affecting the toes, but it can affect many other joints as well. If left alone it can get worse, turn into a chronic problem and even cause permanent damage. Gout sufferers need to realise that there may also be other underlying health problems
http://curegoutpainnow.com - Gout is a painful condition, often affecting the toes, but it can affect many other joints as well. Gout knee is particularly painful. If left alone it can get worse, turn into a chronic problem and even cause permanent damage.
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Many people don’t realize that gout is a type of arthritis. It causes the joint tissue to swell and that puts pressure in that area causing pain.
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Diabetes has already reached global epidemic proportions. Pills aren't the long-term solution and diet alone doesn't work. The missing piece is exercise. But what if you hurt when you walk? Read this presentation to find the answer.
http://curegoutpainnow.com - Gout is a painful condition, often affecting the toes, but it can affect many other joints as well. If left alone it can get worse, turn into a chronic problem and even cause permanent damage. Gout symptoms have to be understood and treated.
Osteoarthritis is the most common form of arthritis. It is caused by the breakdown of cartilage, Ayurveda has the best treatment for all type of arthritis.
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Adult Incontinence is a problem that affects millions of people around the world, and those that are affected by it are spending thousands a year to help manage their conditions. Incontinence can be divided into various parts and Urinary incontinence is one such part affecting men and women. In order to help you in understanding what is Urinary incontinence, what are the types and causes and is there any way to prevent this condition, We have created this video which will tell you everything about Urinary incontinence. Hope you enjoy and like this. For more information on incontinence problems, visit http://wellnessbriefs.com/
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There are plenty of delicious tasting gout recipes that you will be able to try. By eating right you will be taking assertive action towards reducing your chances of problems with gout in the future.
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Finding gout relief fast is very important. Try to consume lots of fresh berries as they can work very fast to help neutralize the uric acid in the body.
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Uric acid crystals are the underlying problem causing gout pain and inflammation. When there is too much uric acid being produced in the body some of it will form hard microscopic crystals which build up in joint areas.
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The best long term results are obtained by eating a properly planned uric acid diet. Any diet plan that is prescribed for gout patients must be able to reduce the level of uric acid in the blood.
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Gout is caused by hyperuricemia. This high concentration leads to the formation of urate crystals, as a result the joints become inflamed and stiff, which causes significant pain.
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If you eat too many purines, you may find that you have increased uric acid levels. The body only needs so many purines to function
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Gout is a form of arthritis, usually first characterised in an acute attack in the joint of the big toe.
Gout generally affects middle-aged and overweight men, but can affect other people too.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
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Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
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NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
2. As you can probably guess from the name, ankle gout involves that part of the body swelling up and becoming very painful.
3. It typically will affect the ankle joint bones, tendons and ligaments and that makes it very hard to walk. Even the toes can swell up and then it can be impossible to get a pair of shoes on.
4. The big toe is the most common location where gout will occur but often it will then spread to the ankles.
5. Typically ankle gout will only affect one leg or the other but some people do have problems with it on both legs at the same time.
6. Not everyone gets gout on the toe though - it may go right to the ankle.
7. That is why people who walk often or who exercise may think that they have sprained or twisted their ankle.
8. This is because the pain and the swelling can come on very suddenly.
9. Someone may be going about their daily activities one moment and begin to feel tightness and some pain.
10. Within hours they can be in the middle of a full blown gout attack. Because it comes on suddenly some people may simply assume that they stepped wrong.
11. These people may treat the area with that in mind and so they likely won’t even go to the doctor for treatment. It can take several days or even weeks for the ankle to stop hurting and for the pain to go away
12. With the wrong type of care though the pain and agony of the situation can linger much longer.
13. Never assume that you know what the problem is — seek medical attention for a proper diagnosis.
14. Ankle gout occurs when there is too much uric acid being created in the body and stored.
15. If you do seek medical attention, an inspection of the affected area of the body, blood testing and urine testing can help determine if gout is present or not.
16. Such testing will show that there are higher than normal levels of uric acid present in the body. If you take high blood pressure medication it could increase your risk of developing gout.
17. Ankle gout is said to be among the most painful types of outbreaks.
18. It is important to make sure you eat a well balanced diet, get exercise, and take action to reduce the chances of future outbreaks.
19. Take a close look at what you eat. Do you consume fresh fruits and vegetables daily? Do you drink enough water?
20. Studies show that the antioxidants found in fruits and vegetables can help to eliminate the build up of uric acid in the body.