This document describes a portable vascular lab called the Vicorder that can perform a variety of arterial and venous tests. It summarizes that the Vicorder is a palm-sized device that uses advanced digital technology to provide high resolution measurements of vascular parameters like ankle-brachial index, pulse wave velocity, and central aortic pressure. It is positioned as an innovative alternative to bulkier, more expensive previous technology for vascular testing and assessment.

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Your CompleteYour Complete
Vascular LabVascular Lab
Welcome!

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Your Complete Vascular Lab
Most comprehensive
Arterial and venous testing
Vascular stiffness testing - central aortic pressures
Photo-Plethysmography
Pulse Volume Recording
Spectral CW Doppler
Bilateral testing
Totally portable
Fast USB-adapter to PC/notebook
No external power supply needed
Size of a palm
Weight 0.6 kg
Integrated remote control
Complete system with notebook fits into one normal briefcase
Configurations tailored to your application

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Most Important Arterial Tests
Ankle-Brachial-Index (ABI)
Most significant in peripheral obstructive disease (PAD)
Bilateral test in less than 5 minutes
No operator dependence – easily done by tech or nurse
Segmental Pressures
Bilateral arm, thigh, ankle, toe pressure
Choice of PPG or Doppler test modalities
Protocols for upper and lower body, fingers and toes
Pulse Volume Recording (PVR)
Recording of plethysmographic pulse wave
Superior resolution of waves
Protocols for upper and lower body, fingers and toes

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Most Important Arterial Tests
Doppler Sonography
Peripheral vascular and cerebro-vascular testing
High resolution spectral analysis
5 or 8 MHz CW probes
Pulse Wave Velocity
Early indicator of arterial stiffness
Indispensable in cardio-vascular risk assessment
Direct measurement, highly reproducible in all ages
No operator dependence – easily done by tech or nurse
Central Aortic Pulse Wave Analysis
Determination of central aortic pressures
Generalized Transfer Function from brachial pressures
Augmentation pressures and Augmentation Index
Diastolic perfusion (SEVR)
Cardiac output, stroke volume

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Additional Arterial Testing Capabilities
Toe pressures and wave forms
ABI with PPG, iPPG, oscillometry, Doppler
Stress testing
Provocation testing
Penile pressures
Reactive testing (Raynaud Syndrome)
Testing of Thoracic Outlet Syndrome

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Most Important Venous Tests
Bilateral venous reflux test
Testing of venous flap patency
Venous outflow test
Testing of venous obstructive disease
Plethysmographic test unilateral
Venous Doppler augmentation test

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Ankle-Brachial-Index ABI
1, 2, 3 - finished
Place cuff at arm
Place PPG on index finger
Place cuff at ankle
Place PPG sensor on toe
Start Test
Cuff will inflate
When target pressure is reached
cuffs will deflate
Press space bar
Read and document ABI
2 min
1 min
3 min
4 min

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ABI Clinical Relevance
Most important parameter in the detection of
peripheral artery occlusive disease PAOD
Prevalence in German private office patients is
18%
(n=6880, age>65 yrs, ABI<0.9)
After 1 year mortality was 2.8% in PAOD patients
(ABI<0.9) and 0.9 in all other patients
After 3 years risk of death was 3.6 times higher
with ABI<0.5 as compared to ABI≥1.1Literature:
Diem, getABI Study, Eur Heart J 2006

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Pulse Wave Velocity
1, 2, 3 - finished
Place neck pad* or arm cuff
Place cuff at thigh
*Only contains a small bladder placed above the carotid artery.
Start Test
Cuffs will inflate
Wave form will be displayed
Press space bar
Enter distance
Read, save or document PWV
2 min
1 min
3 min
4 min

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Pulse Wave Analysis – Central Aortic Pressure
1, 2, 3 - finished
Place cuff at arm.
Start test.
Cuff inflates.
Watch Pulse Wave on screen.
Wait for several beats.
Stop Test. Cuff will deflate.
Watch test results on screen.
Document results.
2 min
1 min
3 min

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Past Vascular Testing Technology
Bulky equipment
Hybrid technology
Analogue signal conditioning
Low resolution analog/digital
conversion (12 bit ADC)
Constant rate bleed valve
Sensitive strain gauge sensors
Expensive
Investment
Service
No PWV or PWA

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Innovative Vicorder Technology
Palm size instrument
Digital technology
Most advanced sensor technology
Mini-electronics
High resolution analogue/digital
conversion (22 bit ADC)
Fast switching “digital” valves
Inexpensive
Fair investment
Practically no service
Combines conventional tests with
PWV and optional PWA

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Most Advanced Signal Conditioning
22 bit signal resolution >4 million points
More than 1,000 better than conventional 12 bit AD
60.0
60.1
mmHG
0
Conventional resolution 1-2 bit
Vicorder resolution >1.000 bit
Conventional devices
require complex electronic signal switching
require analog/electronic signal gain
need analog filtering
Vicorder
no electronic signal switching or amplification
optimum signal condition at all times
digital signal filtering only
Result:
Best Oscillometry
available today

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Wave Form Resolution
Vicorder original tracing
Example: Sphygmocor original tracing
Resolution x 1000Resolution x 1000
ca. 50 mmHg

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Most Advanced Design
High speed valves
Juddering allows for digital control
Bleeding rate adjustable
Extremely reliable
Less moving parts
Service friendly – fewer down times
Lower service cost
Mini-Electronics
No analog signal conditioning
No analog gain control
Fewer (manual) switches
More reliable - fewer down times
Reliable Sensors
Solid state high resolution pressure transducer
Novel photo pulse plethysmograph PPG
No strain gauge sensor needed – less service cost

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Model Configurations
Vascular ModelVascular Model Art. Stiffness -Art. Stiffness -
Central PressuresCentral Pressures
ModelModel
Vascular CompleteVascular Complete
InstrumentInstrument
Peripheral Arterial Tests
Venous Tests
Doppler Option
Art. Stiffness
Central Pressures
Option
Art. Stiffness
Central Pressures
Tests
Peripheral Vascular
Doppler
Option
Art. Stiffness
Central Pressures
Tests
Peripheral Arterial Tests
Venous Tests
Doppler

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Vicorder Markets
Conventional Vascular Markets
Angiology – part of Internal Medicine
Vascular Lab
Phlebology
Vascular Surgery
Epidemiology
Main Competitors
Elcat, Vasolab 5000
Spead, Angiolab 2

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Vicorder Markets
Hypertension/Vascular Stiffness
Cardiology
Hypertensiology
Diabetology
Nephrology – Adult and Pediatric
Public and Corporate Health Programs
Epidemiology
Pulmonary Medicine
Main Competitors
Atcor, Sphygmocor
Tensiomed, Arteriograph
Enverdis, Vascular Explorer
Diatecne, PulsePen