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 Williamsburg, Nov 2014 
Technical Developments in 
Cardiovascular Imaging 
Heinrich Kolem, Forchheim, Germany
Conflict of Interest 
Heinrich Kolem is employee of Siemens 
Healthcare
Content 
Imaging in Interventional Cardiology 
2D, Dose, FFR 
Imaging in Structural Heart Disease 
3D, Echo+Angio combination 
Imaging in the EP Lab 
Multimodality Approach
Interventional Cardiology: 
Not much will change 
Proximal LAD stenosis – before and after succesful PCI
Current and (potential) Future Developments in IC 
 Integration of Angio and IVUS 
 Better tools for CTO 
 Limited use of „Imaging based“ FFR 
 Dose considerations
Demonstration of CFD 
(Computational Fluid Dynamic) 
 Calculate flow based 
on patient specific 
parameter 
 Calculate Functional 
Flow Reserve (FFR) 
based on these data
Dose 
 Biggest Influence on Dose is by User 
(frames/s, filtering, collimation) 
 Besides User Support the only Way to improve is new 
Technology 
 Look at all Dose Calculations with Common Sense: 
natural yearly dose 1-10 mSv (avg. 2.5mSv) 
1mSv=1 000 000 nSv 
 All Dose values can be calculated based on ABSOLUT 
VALUES (nGy/frame)
Crystalline Silicon Sensor for ultra low dose fluoroscopy 
Page 8 
Amorphous Silicon 
Passive Matrix 
Sensor 
Scintillator 
Low Dose X_Ray 
Electronic Noise 
electronic noise 
visible 
in low dose imaging 
Amplifier
Crystalline Silicon sensor for ultra low dose fluoroscopy (CMOS technology) 
Page 9 
Crystalline Silicon 
Active Matrix 
On Pixel Amplification Electronic Noise 
On Pixel Amplifier 
Sensor 
Scintillator 
less electronic noise 
Ultra Low Dose X_Ray 
visible 
in low dose imaging
Amorphous silicon detector Crystalline silicon detector 
Visualization of transseptal needle with ultra-low-dose fluoroscopy at 1 nGy, 
zoom 16 cm 
PaPgaeg 1e0 1 0 
© Siemens AG 2012. All rights reserved. HIM-AX-12-13-063 
Crystalline silicon detector 
For imaging at ultra-low-dose levels 
November 2012 Siemens Healthcare, Angiography & Interventional X-Ray Systems
Dose Reduction using CMOS detector technology 
© Siemens AG 2012. All rights reserved. Created for HAKM 2012. 
For internal use only – note that certain products and/or product claims may not be available for use in every country. 
Page 11 
40 nGy 6 nGy 
Courtesy of University Hospital Basel
Structural Heart Disease 
3D and Multimodality Applications 
Page 12 2014-10-20
Aortic Valve Replacement
Fusion with Trans-Esophageal Echo (TEE) 
Real-Time Fusion 
Fusion
The Electro Physiology Lab 
 3D, Special Dose Saving, Multimodality Combinations
Intern © Siemens AG 20XX Alle Rechte vorbehalten. 
Seite 16 XX.XX.20XX 
Autor / Abteilung 
Cardiac 4D roadmap
Electro-Magnetic Tracking 
gMPS – guided Medical Positioning System 
MPS sensor
X-ray proof of catheter tip position Radiation-free navigation with gMPS 
 Record one flouro scene 
with ECG and 
respiratory signal 
 Play continuously back 
triggered by ECG 
 Overlay catheter tips 
localized by 
electromagnetic tracking
Development and Clinical Evaluation of Multi-Modality 
Applications – 
Evolution of Multi-Modality
of Multi-Modality Applications – 
Evolution of Multi-Modality
Summary 
Imaging in Interventional Cardiology: 
2D will stay, Improvements in Dose, FFR 
Imaging in Structural Heart Disease 
3D, Echo+Angio combination 
Imaging in the EP Lab 
Smart Dose Reduction, Multimodality Approach

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Technical Developments in Cardiovascular Imaging

  • 1.  Williamsburg, Nov 2014 Technical Developments in Cardiovascular Imaging Heinrich Kolem, Forchheim, Germany
  • 2. Conflict of Interest Heinrich Kolem is employee of Siemens Healthcare
  • 3. Content Imaging in Interventional Cardiology 2D, Dose, FFR Imaging in Structural Heart Disease 3D, Echo+Angio combination Imaging in the EP Lab Multimodality Approach
  • 4. Interventional Cardiology: Not much will change Proximal LAD stenosis – before and after succesful PCI
  • 5. Current and (potential) Future Developments in IC  Integration of Angio and IVUS  Better tools for CTO  Limited use of „Imaging based“ FFR  Dose considerations
  • 6. Demonstration of CFD (Computational Fluid Dynamic)  Calculate flow based on patient specific parameter  Calculate Functional Flow Reserve (FFR) based on these data
  • 7. Dose  Biggest Influence on Dose is by User (frames/s, filtering, collimation)  Besides User Support the only Way to improve is new Technology  Look at all Dose Calculations with Common Sense: natural yearly dose 1-10 mSv (avg. 2.5mSv) 1mSv=1 000 000 nSv  All Dose values can be calculated based on ABSOLUT VALUES (nGy/frame)
  • 8. Crystalline Silicon Sensor for ultra low dose fluoroscopy Page 8 Amorphous Silicon Passive Matrix Sensor Scintillator Low Dose X_Ray Electronic Noise electronic noise visible in low dose imaging Amplifier
  • 9. Crystalline Silicon sensor for ultra low dose fluoroscopy (CMOS technology) Page 9 Crystalline Silicon Active Matrix On Pixel Amplification Electronic Noise On Pixel Amplifier Sensor Scintillator less electronic noise Ultra Low Dose X_Ray visible in low dose imaging
  • 10. Amorphous silicon detector Crystalline silicon detector Visualization of transseptal needle with ultra-low-dose fluoroscopy at 1 nGy, zoom 16 cm PaPgaeg 1e0 1 0 © Siemens AG 2012. All rights reserved. HIM-AX-12-13-063 Crystalline silicon detector For imaging at ultra-low-dose levels November 2012 Siemens Healthcare, Angiography & Interventional X-Ray Systems
  • 11. Dose Reduction using CMOS detector technology © Siemens AG 2012. All rights reserved. Created for HAKM 2012. For internal use only – note that certain products and/or product claims may not be available for use in every country. Page 11 40 nGy 6 nGy Courtesy of University Hospital Basel
  • 12. Structural Heart Disease 3D and Multimodality Applications Page 12 2014-10-20
  • 14. Fusion with Trans-Esophageal Echo (TEE) Real-Time Fusion Fusion
  • 15. The Electro Physiology Lab  3D, Special Dose Saving, Multimodality Combinations
  • 16. Intern © Siemens AG 20XX Alle Rechte vorbehalten. Seite 16 XX.XX.20XX Autor / Abteilung Cardiac 4D roadmap
  • 17. Electro-Magnetic Tracking gMPS – guided Medical Positioning System MPS sensor
  • 18. X-ray proof of catheter tip position Radiation-free navigation with gMPS  Record one flouro scene with ECG and respiratory signal  Play continuously back triggered by ECG  Overlay catheter tips localized by electromagnetic tracking
  • 19. Development and Clinical Evaluation of Multi-Modality Applications – Evolution of Multi-Modality
  • 20. of Multi-Modality Applications – Evolution of Multi-Modality
  • 21. Summary Imaging in Interventional Cardiology: 2D will stay, Improvements in Dose, FFR Imaging in Structural Heart Disease 3D, Echo+Angio combination Imaging in the EP Lab Smart Dose Reduction, Multimodality Approach