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Vascular anomalies
•
Vascular anomalies
• Abnormal swellings made up of blood
vessels.
Vascular anomalies:
Classification
Two-
• Hemangioma
• Vascular Malformations
1.High Flow -AV fistula
2.Low flow
– capillary malformation - port-wine stains
– venous malformations Cavernous hemangioma.
– Lymphatic malformations
Hemangioma
• Vascular tumor-like structure
• Present at or around birth or appeared later
in life.
• Self-involuting
• Growing faster than body of patient
• Eventually disappear
Vascular Malformations
• Enlarged or abnormal vessels
• present at birth
• Grow with rest of the body of patient
• Essentially permanent.
Etiology
Etiology
• Congenital
– Mostly sporadic
– Rarely autosomal dominant
• Traumatic
• Infections /Infestation
• Autoimmunity
• Neoplastic (Benign/Malignant)
• Degenerative
Etiology
• Congenital
– Mostly sporadic
– Rarely autosomal dominant
• Traumatic
• Infections /Infestation
• Autoimmunity
• Neoplastic (Benign/Malignant)
• Degenerative
Clinical Features
Clinical Features
• Demography
• Symptoms
• Signs
• Complications
Demography
Demography
• Common in whites 10% of live births
Symptoms:
Symptoms: site
• Head and neck (59%)
• Trunk (24%)
• Lower extremities (10%)
• Upper extremities (7%)
• Liver and other viscra
Symptoms: Appearance
• Colored congenital lesion
• Vary from a hypopigmented macule to a
bruiselike macule.
• Lymphangioma-Soft doughy masses that
are located in the head and neck region,
Symptoms:Natural history
• Proliferative postnatal growth phase that
lasts for 3-9 months
• Gradual involution that occurs over 2-6
years.
• Involution is usually complete by age 7-10
years.
Symptoms:Complications
• In some cases, hemangiomas can be life-
threatening or severely problematic,
interfering with eating, breathing, seeing,
hearing, and speaking.
Diagnostic Studies
• MRI
• USG
Management
Management
• Watchful waiting
• Capillary malformations - argon laser or a
flashlamp-pumped pulsed dye laser (PDL).
• Lymphangiomas -surgical excision
• Systemic glucocorticoids
• Beta blocker propranolol
• Triamcinolone
• Interferon alfa-2a
• Ethanol sclerotherapy for venous
malformation
Associated syndromes
Associated syndromes
• Klippel-Trenaunay-Weber syndrome
• Sturge-Weber syndrome
Klippel-Trenaunay-Weber
syndrome
• Triad
– Vascular tumors of the limbs, trunk, or
perineum;
– Varicose veins
– Hypertrophy of the extremities
Sturge-Weber syndrome
• Facial lesion
• Epileptic seizures
• Hemiplegia
• Visual field defects
• Glaucoma.
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Editor's Notes

  1. drpradeeppande@gmail.com 7697305442
  2. The terminology used to define, describe and categorize vascular anomalies, abnormal lumps made up of blood vessels, has changed. The term hemangioma originally described any vascular tumor-like structure, whether it was present at or around birth or appeared later in life. Mulliken et al. categorized these conditions into two families: one of self-involuting tumors, growing lesions that eventually disappear, and another of malformations, enlarged or abnormal vessels present at birth and essentially permanent. The importance of this distinction is that it makes it possible for early-in-life differentiation between lesions that will resolve versus those that are permanent. Examples of permanent malformations include port-wine stains (capillary vascular malformation) and masses of abnormal swollen veins(venous malformations).[3] The Mulliken categorisation has received major confirmation following discovery of the Glut-1 marker.[citation needed]
  3. The terminology used to define, describe and categorize vascular anomalies, abnormal lumps made up of blood vessels, has changed. The term hemangioma originally described any vascular tumor-like structure, whether it was present at or around birth or appeared later in life. Mulliken et al. categorized these conditions into two families: one of self-involuting tumors, growing lesions that eventually disappear, and another of malformations, enlarged or abnormal vessels present at birth and essentially permanent. The importance of this distinction is that it makes it possible for early-in-life differentiation between lesions that will resolve versus those that are permanent. Examples of permanent malformations include port-wine stains (capillary vascular malformation) and masses of abnormal swollen veins(venous malformations).[3] The Mulliken categorisation has received major confirmation following discovery of the Glut-1 marker.[citation needed]
  4. Vascular malformations - These are subdivided into high-flow (arterial, arteriovenous) malformations and slow-flow (venous, capillary, lymphatic) malformations;