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[object Object],D-r Mitova MU-Sofia
Poliomyelitis ,[object Object],[object Object],[object Object],[object Object]
Poliovirus ,[object Object],[object Object],[object Object],[object Object]
Poliomyelitis Pathogenesis ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
 
Poliovirus Epidemiology ,[object Object],[object Object],[object Object]
Poliovirus Vaccine ,[object Object],[object Object],[object Object],[object Object],[object Object]
Inactivated Polio Vaccine ,[object Object],[object Object],[object Object],[object Object]
Oral Polio Vaccine ,[object Object],[object Object],[object Object],[object Object]
Inactivated Polio Vaccine ,[object Object],[object Object],[object Object],[object Object]
Oral Polio Vaccine ,[object Object],[object Object],[object Object],[object Object]
Polio Vaccination Recommendations, 1996-1999 ,[object Object],[object Object],[object Object]
Polio Vaccination Recommendations ,[object Object],[object Object],[object Object]
Polio Vaccination Schedule  Vaccine OPV OPV OPV OPV OPV Age 2 months 3 months 4 months 16months 6 years Minimum Interval --- 4 wks 4 wks
[object Object],Vaccine IPV IPV IPV IPV Age 2 months 4 months 6-18 months 4-6 years Minimum Interval --- 4 wks 4 wks 4 wks
Schedules that Include  Both IPV and OPV ,[object Object],[object Object],[object Object]
Polio Vaccination of Adults ,[object Object],[object Object]
Polio Vaccination of Unvaccinated Adults ,[object Object],[object Object],[object Object]
Polio Vaccination of Previously Vaccinated Adults ,[object Object],[object Object],[object Object],[object Object],[object Object]
Polio Vaccine Adverse Reactions ,[object Object],[object Object],[object Object]
Vaccine-Associated Paralytic Polio ,[object Object],[object Object],[object Object],[object Object],[object Object]
Vaccine-Associated Paralytic Polio (VAPP) 1980-1998 ,[object Object],[object Object],[object Object],[object Object]
Polio Vaccine Contraindications and Precautions ,[object Object],[object Object]
Polio Eradication ,[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object]
Distribution of laboratory-confirmed wild poliovirus type 1 cases (N = 476) European Region, 2010 (458 in Tajikistan, 14 in Russia, three in Turkmenistan, and one in Kazakhstan)
Rubella ,[object Object],[object Object],[object Object],[object Object]
Rubella Virus ,[object Object],[object Object],[object Object],[object Object]
Rubella Pathogenesis ,[object Object],[object Object],[object Object],[object Object]
Rubella Clinical Features ,[object Object],[object Object],[object Object],[object Object]
 
Rubella Complications Arthralgia or arthritis children adult female Thrombocytopenic  purpura Encephalitis Neuritis Orchitis rare up to 70% 1/3000 cases 1/6,000 cases rare rare
Congenital Rubella Syndrome ,[object Object],[object Object],[object Object],[object Object]
Congenital Rubella Syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rubella Laboratory Diagnosis ,[object Object],[object Object],[object Object]
Rubella Epidemiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Measles ,[object Object],[object Object],[object Object],[object Object]
Measles Virus ,[object Object],[object Object],[object Object],[object Object]
Measles Pathogenesis ,[object Object],[object Object],[object Object],[object Object]
Measles Clinical Features ,[object Object],[object Object],[object Object],[object Object],Prodrome
Measles Clinical Features ,[object Object],[object Object],[object Object],[object Object],[object Object],Rash
 
 
Condition Diarrhea Otitis media Pneumonia Encephalitis Hospitalization Death Percent reported 8 7 6 0.1 18 0.2 Measles Complications Based on 1985-1992 surveillance data
Measles Laboratory Diagnosis ,[object Object],[object Object],[object Object]
Measles Epidemiology ,[object Object],[object Object],[object Object],[object Object]
Mumps ,[object Object],[object Object],[object Object],[object Object]
Mumps Virus ,[object Object],[object Object],[object Object],[object Object]
Mumps Pathogenesis ,[object Object],[object Object],[object Object],[object Object]
Mumps Clinical Features ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Mumps Complications CNS involvement Orchitis Pancreatitis Deafness Death 15% of clinical cases 20%-50% in post- pubertal males 2%-5% 1/20,000  1-3/10,000
Mumps Laboratory Diagnosis ,[object Object],[object Object],[object Object],[object Object]
Mumps Epidemiology ,[object Object],[object Object],[object Object],[object Object]
Measles Mumps Rubella Vaccine ,[object Object],[object Object],[object Object]
MMR  Indications ,[object Object],[object Object],[object Object]
Second Dose Recommendation ,[object Object],[object Object],[object Object]
MMR Adverse Reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],MMR Vaccine Contraindications and Precautions
MMR Vaccine and Autism ,[object Object],[object Object]
Measles and Mumps Vaccines and Egg Allergy ,[object Object],[object Object],[object Object]
Measles Vaccine and HIV Infection ,[object Object],[object Object],[object Object]
PPD and Measles Vaccine ,[object Object],[object Object],[object Object]

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Vaccine3 polio

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  • 15. Polio Vaccination Schedule Vaccine OPV OPV OPV OPV OPV Age 2 months 3 months 4 months 16months 6 years Minimum Interval --- 4 wks 4 wks
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  • 28. Distribution of laboratory-confirmed wild poliovirus type 1 cases (N = 476) European Region, 2010 (458 in Tajikistan, 14 in Russia, three in Turkmenistan, and one in Kazakhstan)
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  • 34. Rubella Complications Arthralgia or arthritis children adult female Thrombocytopenic purpura Encephalitis Neuritis Orchitis rare up to 70% 1/3000 cases 1/6,000 cases rare rare
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  • 46. Condition Diarrhea Otitis media Pneumonia Encephalitis Hospitalization Death Percent reported 8 7 6 0.1 18 0.2 Measles Complications Based on 1985-1992 surveillance data
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  • 54. Mumps Complications CNS involvement Orchitis Pancreatitis Deafness Death 15% of clinical cases 20%-50% in post- pubertal males 2%-5% 1/20,000 1-3/10,000
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Editor's Notes

  1. Increased risk of VAPP in immunodeficient children and persons >18 years of age.