Using megatrends to understand future opportunities and challenges is crucial for business success. Megatrends are major long-term shifts in society with wide-ranging consequences. They can impact businesses in both obvious and unexpected ways. To assess megatrends, companies should identify key trends, discuss their potential impacts internally in a multidisciplinary way, and draw conclusions to inform strategy. Understanding megatrends helps companies innovate their business models, strategies, and operations to thrive in the future.