1) The document provides an overview of common upper extremity injuries, including fractures of the clavicle, scapula, humerus, elbow, forearm, and wrist.
2) It describes the anatomy, mechanisms of injury, clinical features, diagnosis, and treatment approaches for each type of fracture. Conservative treatment involves splinting or casting while surgical treatment uses plates, screws, or other internal fixation devices.
3) Complications of these injuries include nonunion, malunion, stiffness, nerve damage, and in some cases may require further surgery if not properly treated.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
3. INTRODUCTION
• Upper extremity injuries are routinely encountered in the ED
• Adequate assessment and proper handling significantly
reduces morbidity
• Approach to patients should be designed based on their
specific injury
4. “A broken bone can heal, but
the wound a word opens can
fester forever.”
—Jessamyn West
6. • An s shaped bone
• Mid portion is the thinnest having no accompanying ligamentous or
muscular attachment
• Injury can occur following
• Fall on an outstretched hand
• Blow to the clavicle
• Birth trauma
• Common in young individuals who participate in sports like bicycling
and frequent violent collisions.
Clavicle
8. Clinical features
Fracture and crepitus might be palpated
Arm is slumped inward and
downward
Limited range of motion
Swelling, deformity and tenderness
Sagging, shortening, tenting
10. Imaging
• Best initial test: X- ray in two projections (AP
and 45 degree cephalic tilt view)
• CT/MRI when associated injuries are
suspected or inconclusive x- rays.
• Arteriography in suspected vascular injury
• U/S in suspected fracture in children
12. Treatment contd….
• Conservative treatment similar to group 1
fractures
• Severe cases might need surgical
correction
• It is vital to assess for the presence
of intrathoracic trauma
• If present emergency intervention is
required
Medial (Group 3 fractures)
15. • A flat bone triangularly shaped
• Can be injured due to
• High energy trauma to the
shoulder, esp polytrauma
• Fall from outstretched hand
• Fractures occur relatively infrequently
• Account only 0.4-0.9% of all fractures
Scapula
17. Clinical features
Arm is held in adduction
Assosciated injury of ipsilateral
lung & thoracic cage
Localized tenderness over the scapula
Fracture of the ribs
18. Imaging
• Chest x-ray
- Overlying structures obscure the scapula
• Scapular series
- AP, lateral and axillary view
• CT scan
- For associated injuries
22. • The head of the humerus is larger than the shallow glenoid fossa,
• Trauma (e.g., falling on an outstretched arm)
• Predisposing factors for recurrent shoulder dislocation
a. Loose joint capsule
b. Damage to the glenohumeral ligament
c. Rotator cuff tear
d. Bankart lesion and Hill-Sachs lesion
• For posterior dislocation: uncoordinated muscle contraction
(e.g., seizure, electrical shock)
Glenohumeral joint
24. Clinical features
A palpaple dent present at point where humerus lies
Inability to move the shoulder
Empty glenoid fossa
Severe shoulder pain
25. Clinical features
Humeral head palpated below coracoid process
Arm held in external rotation and slight abduction
Posterior
inferior
Antereor
Prominenence of posterior shoulder with ant flattening
Prominent coracoid process
Arm held above the head, pt unable to adduct arm
Neurologic dysfunction, especially in involvment of
axillay nerve
27. Shoulder X-ray
• AP and lateral view to confirm dislocation
and exclude fracture
• For posterior dislocation
- axillary + scapular lateral views
• Light bulb sign – diagnostic of posterior
dislocation
28. Hill Sachs lesion
• Seen in 35-40% of patients with
anterior dislocation
• Is an indentation of the posterolateral
surface of the humeral head
• Best detected by MRI
Bankart lesion
• Injury of the anterior inferior tip of the
glenoid labrum
• Occurs due to traumatic anterior
shoulder dislocation
29. Treatment
Immobilisation of joint with a splint/sling
Analgesia
Emergent management
Closed reduction indicated in
• Inferior dislocation and most anterior dislocation
• Uncomplicated posterior dislocation presenting
early
• Cases with no evidence of major arterial injury or
assosciated injury and fracture
Conservative management
30. Techniques of reduction
Gentle external rotation or outward pressure
on the proximal humerus may aid
reduction
Traction counter trachtion
method
34. Treatment
indicated in
• Unsuccessful closed reduction
• Concomitant dislocated fracture of humerus,
clavicle or scapula
• Displaced bankart lestion
• Recurrent shoulder dislocations
• To prevent recurrent dislocation in the future
Surgical management
Continious neurovascular monitoring before and after reduction to detect axillary nerve
and artery damage
37. • Can result from direct or indirect trauma
• Fall with axial loading on an outstretched hand
• Motor vehicle accidents
• Violent seizures
• Direct blow to the back of the humerus
• Pathologic fractures
• Pagets disease
• Metastatic bone disease
Humerus
39. Proximal humerus fracture
• Common in the elderly
• Has four major segments
• Anatomical neck
• Humeral shaft
• The greater tuberosity
• Lesser tuberosity
• Neer classification : based on
displacement of these segments
40. Neer Classification
One part fracture : line involves 1-4 parts but no part displaced
Two part fracture : line involves 2-4 parts and 1 part is displaced
Three part fracture: line involve 3-4 parts and 2 part are displaced
Four part fracture: line involve 4 part 3 part are displaced
41.
42. Humeral shaft fracture
• Classification according to location
- Proximal third
- Middle third
- Distal third
• Classification according to communition
- Type A (No communition)
- Type B (Butterfly fragment)
- Type C (communition present)
43. Distal humerus fracture
• According to anatomical site
- Lateral / medial fractures
- Supracondylar fractures
- transverse and above the epicondyles
- The most common pediatric elbow #
• AO classification
• Type A: extra-articular fracture
• Type B : Partial articular
• Type C: Complete articular
44. Clinical features
Local swelling, deformity, crepitus
Events like radial nerve palsy
Severe local pain
Exacerbated during palpation or movement
Shortening of the arm
Especially in fractures of the middle third(mid shaft)
of humerus
45. Diagnosis
X-ray
• AP and lateral views of the humerus will
show radiographic features of fractures
CT
• if x-ray is not diagnostic
MRI
• If pathologic fracture is suspected
• To evaluate rotator cuff injury
46. Treatment
For non-displaced closed fractures
Hanging arm cast and sling for 1-2 weeks then follow up then brace
Early physical therapy to restore function
Conservative management
Indicated in
• Open fractures
• Displaced fractures that cant be reduced
• Assosciated injuries (nerve & vessles)
• Floating elbow (humerus + forearm)
Surgical management
47. Treatment
Procedures include
• Internal fixation – especially in supracondylar
fracture
• External fixation (Open fractures and polytrauma)
• Arthroplasty of humeral head or elbow (complex
fractures)
- Especially in elderly patients
Surgical management
52. Distal Humeral Fractures
• Classified according to anatomical site
• Supracondylar – most common pediatric elbow fracture
• Transcondylar
• Intercondylar
• Condylar
• Epicondylar
• Capitellum
• Trochlear
53. Supracondylar fracture
• Occurs just above the two condyles of the lower humerus
• Commonly seen in Children between the age of 5-10years
• Two types
1. Posterior angulation or
displacement (extension) -
95%
2. Anterior angulation or
displacement (flexion)
54. Clinical features
• Pain and swollen elbow
• S – deformity of elbow
• Dimple sign
• Arm is short
55.
56. Diagnosis
• AP and lateral X-ray of elbow
• Also important to check for adequacy of reduction
• AP view measurements – Baumann’s Angle
• Lateral view measurements and signs
– Fat pad sign (ant &post)
- Anterior humeral line (displaced)
57. • Baumann’s angle:
• Useful to assess the accuracy of distal
fragment reduction
• Line on the longitudinal axis of humeral
shaft and line through the coronal axis of
the capitellar physis
• Normally 90 degrees
• if < 90 – cubitus valgus -
• > 90 cubitus varus -
58. Management
1. Conservative therapy
• Indication: nondisplaced, closed fractures
• Procedures
• Hanging-arm cast or coaptation splint and sling for approx. one to
two weeks with subsequent follow-up x-ray and brace
• Early physical therapy to restore function
59. 2. Surgical treatment
• Indication: open fractures, displaced fractures that cannot be
reduced, associated injuries (nerves, blood vessels), floating
elbow (simultaneous humerus and forearm fracture),
• Procedures
• Internal fixation using plates and screws, or intramedullary
implants (especially supracondylar fractures)
• External fixation (e.g., open fracture, polytrauma)
• Arthroplasty of humeral head or elbow (e.g., in complex
fractures), especially in elderly patients
60. Complications
• Early= Compartment syndrome
Brachial Artery injury
Nerve Injury : Median, Ulnar or Radial
• Late= Stiffness
Volkmann's Ischemic contracture refusal to open hand, pain
with passive extension of fingers, and forearm pain out of
proportion
Mal-Union
61.
62. Radial Head Fractures
• Most common fractures of the elbow
• Mechanism of Injury
• FOOSH with elbow extended and the forearm pronated ( causes impaction of
the radial head against the capitulum
• In children more likely to fracture neck of radius
Clinical Features
• Pain on supination and pronation
• Local tenderness posterolateral to the proximal end
63. Diagnosis
• AP and Lateral x-ray
Complications
• Joint stiffness
• Osteoarthritis
• Recurrent instability (if MCL is injured and radial head excised)
64.
65. • Management
• Adults
• Nondisplaced fractures – supporting the elbow in a collar and cuff
• Displaced – ORIF
• Comminuted – reconstruct the radial head
• Children
• Collar and cuff and exercises commenced after 1 week
• Displacement of >30 degrees – closed reduction
• If fails – open reduction
66. Elbow Dislocation
• Highest incidence in the young 10-20 years and usually sports injuries
• Posterior dislocations most common
• Mechanism of injury – fall on outstretched hand
• CP – Patients typically present guarding the injured extremity
- limited range of motion: inability to flex or extend the elbow
- Usually has gross deformity (Prominent olecranon posteriorly)
and swelling
- Limb length discrepency
- nerve injury (10%), rarely brachial artery
67. Diagnosis
• X-ray of the elbow joint
• AP view and lateral view to confirm dislocation and exclude fracture
• Posterior fat pad sign: seen in patients with
concomitant fractures (usually of the humerus/radial head)
68. Management
• Conservative – closed reduction
• can be done by single person or two people
• Operative – open reduction and stabilization
• Associated fractures
69.
70. • After reduction
• Palpable “clunk” is heard
• Post reduction film
• Move elbow in all directions and assess stability
• Splint in long arm posterior splint
71. Associated Injuries
• Fracture of radial head (5-11%)
• Fracture of coronoid process (5-10%)
• Fracture of medial or lateral epicondyle (12-34%)
• Fracture of olecranon
74. Fracture of the Forearm bones
• The radius and ulna are commonly fractured together
• Highest ratio of open to closed
• More common in males than females
• Mechanisms of Injury
• MVA, falls from height, or direct blow
• Clinical features
• Typically present with gross deformity of the forearm with pain, swelling and
loss of function at the hand
75. • Diagnosis
• AP and Lateral view of the forearm with
the entire elbow and joints
76. • Management
• Conservative
• In children, closed treatment is usually succcessful because the
tough periosteum tends to guide and then control
• Full length cast – from axilla to metacarpal shaft
• Operative
• All adults unless the fragments are in close apposition
• Most fractures heal within 8-12 weeks
77. Monteggia’s Fracture-Dislocation
• Fracture of the proximal third of the ulna with dislocation of the
proximal head of radius
• Mechanism of Injury – FOOSH with forced pronaiton
• Clinical Features
• Pain and swelling at the elbow
• Angular deformity of the forearm
• Shortened arm
• Dislocated head of radius maybe masked by swelling
78. • Diagnosis
• AP and Lateral X-ray
• Ulnar fracture may be obvious and distract
from the radial dislocation
• Management
• ORIF with plate and screws
• Radial head usually reduced once the ulna
has been fixed
79. Galeazzi’s Fracture-Dislocation
• Fracture of the distal third of the radial shaft accompanied by a
dislocation of the distal radioulnar joint
• Mechanism of action- FOOSH with
hyperpronated forearm
• Clinical features
• Tenderness over the lower end of ulna
• Management
• ORIF
82. Colles’ Fracture
• Most common fracture in Osteoporotic bones (elderly/post-menopausal women)
• Distal radial metaphysis fracture that is dorsally angulated and displaced
proximally and dorsally
• Clinical features
• Dinner fork deformity
86. Smith fracture/ Reverse Colles
• Fracture of the distal radius with ventral displacement
• Clinical features
• Garden spade deformity
• Diagnosis
• PA and lateral film of the wrist
87.
88.
89. Scaphoid Fracture
• Most common carpal bone fractured.
• Pain along the radial aspect of the wrist
• Pain with active movement of the thumb
• Snuffbox tenderness
Assess for compartments syndrome with the 6 pp’s: pain, pallor, pulselessness, paresthesia, paralysis, and poikilothermia
Weak pulses : possible injury to subcclavian artery
Dysfun of distal nerve: possible injury to the brachial plexus
Massive swelling and discoloration : possible injury to subclavian vein
Assess for compartments syndrome with the 6 pp’s: pain, pallor, pulselessness, paresthesia, paralysis, and poikilothermia
Weak pulses : possible injury to subcclavian artery
Dysfun of distal nerve: possible injury to the brachial plexus
Massive swelling and discoloration : possible injury to subclavian vein
For posterior other views may be unreliable because they may not reveal posterior humeral head displacement and can give the false impression that there is dislocation
As humeral head dislocates posteriorly, it is forced to internal rotation and appears circular like a light bulb
Assess for compartments syndrome with the 6 pp’s: pain, pallor, pulselessness, paresthesia, paralysis, and poikilothermia
Weak pulses : possible injury to subcclavian artery
Dysfun of distal nerve: possible injury to the brachial plexus
Massive swelling and discoloration : possible injury to subclavian vein
Fractured is said to be displaced when the angle bn segments is >45 degree or distance bn them is greater than 1 cm
Fractured is said to be displaced when the angle bn segments is >45 degree or distance bn them is greater than 1 cm
Fractured is said to be displaced when the angle bn segments is >45 degree or distance bn them is greater than 1 cm
Assess for compartments syndrome with the 6 pp’s: pain, pallor, pulselessness, paresthesia, paralysis, and poikilothermia
Weak pulses : possible injury to subcclavian artery
Dysfun of distal nerve: possible injury to the brachial plexus
Massive swelling and discoloration : possible injury to subclavian vein
Olecranon fracture
Elbow dislocation
Radial head fracture
Adults – high velocity injury
Mechanism – 1. FOOSH
2. Direct violence/blow while elbow is flexed
One of the spikes of proximal fragment penetrating the muscle and tethering the skin
Definition of cubitus valgus and cubitus varus
(most serious compartment syndrome of the hand)
conservatively with immobilization and early range of motion exercises, ice, elevation, analgesics and ortho in 1 week
On the lateral view, both ulna and radius are displaced posteriorly
Assess
Two person: position forearm supine.
While an assistant applies a stabilzing countertraction force on the upper arm, use one hand to apply longitudnal traction on the wrist and forearm. With the other hand manipulate elbow to correct medial, lateral displacement. Then apply slow and steady downward pressure to the proximal forearm to disengage the coronoid processs from the olecranon fossa. Continue distal traction and flex elbow
1. The patient may also be supine with the arm adducted across the torso and the elbow slightly flexed (Figure 270-10). Have an assistant apply
longitudinal traction on the wrist and forearm. Then, grasp the elbow, positioning both thumbs on the olecranon, and apply firm pressure
against the olecranon to push it up and over the trochlea and back into anatomic position. Apply countertraction with the fingers against the
distal humerus.
2. Single-person reduction technique with the patient in a seated position (Figure 270-11).
Place an elbow in the patient’s antecubital fossa, then grasp the patient’s hand or wrist. Flex the patient’s forearm while leveraging a force into the
antecubital fossa to bring the olecranon back into anatomic position.
Solitary fracture is uncommon
High energy injury
Symptoms and signs
Swelling, deformity and tenderness
Nerve injury – uncommon with closed injuries
Vascular injury – not usually a concern due to the excellent collateral ciruclation
Torus fracture, also known as a buckle fracture is the most common occurrence following a fall, as the wrist absorbs most of the impact
Torus or Greenstick
Minimal angulation long arm splint
Angulation > 15 degrees closed reduction and cast immobilization
Surgical intervention
Failure of closed reduction
Non-displaced fractures in adults
Immobilization with long arm splint
Ortho within 1-2 days
Piano key sign
Lateral view best for angulation
FOOSH on dorsiflexed hand
AP and later view
Ortho consult
Open
Neurovascular injury
Unstable
>20 degrees of angulation
Intra articular involvement
Marked comminution
>1cm shortening
Management
Similar to colles
Difference in closed reduced
Pressure is applied on the volar side
Scaphoid tubercle tenderness
Pain with active movement of the thumb
Snuffbox tenderness
Snuffbox: triangular depression on the lateral aspect of the dorsum of the hand.
Scaphoid view for subtle fractures, view with ulnar deviation of the wrist and full