Co-Chairs, Dr. Toby A. Eyre, MBChB, DipMedEd, MRCP, FRCPath, MD, and Anthony R. Mato, MD, MSCE, discuss B-cell cancers in this CME activity titled “Upgrading the Sequential Therapy Tool Kit for B-Cell Malignancies: New Evidence on the Individualized Use of BTK Inhibitors in Relapsed/Refractory CLL/SLL and MCL.” For the full presentation, downloadable Practice Aids, and complete CME information, and to apply for credit, please visit us at https://bit.ly/3x2TlMR. CME credit will be available until August 14, 2023.