Harnessing Innovation in Bladder Cancer Care: Strategies for Effectively Implementing Modern Therapeutic Advances Across the Disease Continuum

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PVI, PeerView Institute for Medical Education

Chair and Presenters, Neal D. Shore, MD, FACS, Ashish M. Kamat, MD, MBBS, and Joshua J. Meeks, MD, PhD, discuss bladder cancer in this CME/MOC/NCPD/AAPA/IPCE activity titled “Harnessing Innovation in Bladder Cancer Care: Strategies for Effectively Implementing Modern Therapeutic Advances Across the Disease Continuum.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/3PH0RVQ. CME/MOC/NCPD/AAPA/IPCE credit will be available until June 2, 2025.

Health & Medicine

Harnessing Innovation in Bladder Cancer Care: Strategies for Effectively Implementing Modern Therapeutic Advances Across the Disease Continuum

Co-Chairs, Stephen Salloway, MD, MS, and Sharon J. Sha, MD, MS, prepared useful Practice Aids pertaining to Alzheimer's disease for this CME/MOC/NCPD/AAPA activity titled “Preparing Your Practice for the New Era of Amyloid-Targeting Therapies in Alzheimer's Disease: Expert Insights on Key Evidence, Administrative and Clinical Considerations, and Best Practices for Individualized, Patient-Centered Care.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at https://bit.ly/3twjpAt. CME/MOC/NCPD/AAPA credit will be available until June 19, 2025.

Preparing Your Practice for the New Era of Amyloid-Targeting Therapies in Alz...

PVI, PeerView Institute for Medical Education

Co-Chairs, Stephen Salloway, MD, MS, and Sharon J. Sha, MD, MS, discuss Alzheimer's disease in this CME/MOC/NCPD/AAPA activity titled “Preparing Your Practice for the New Era of Amyloid-Targeting Therapies in Alzheimer's Disease: Expert Insights on Key Evidence, Administrative and Clinical Considerations, and Best Practices for Individualized, Patient-Centered Care.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at https://bit.ly/3twjpAt. CME/MOC/NCPD/AAPA credit will be available until June 19, 2025.

Candid Conversations on Modern Urothelial Cancer Management: Personalizing Pa...

PVI, PeerView Institute for Medical Education

Chair and Presenters, Andrea Necchi, MD, Matthew D. Galsky, MD, Shilpa Gupta, MD, and Michiel S. van der Heijden, MD, PhD, prepared useful Practice Aids pertaining to bladder cancer for this CME/MOC/NCPD/AAPA/IPCE activity titled “Candid Conversations on Modern Urothelial Cancer Management: Personalizing Patient Care Using the Latest Evidence and Innovative Therapeutic Strategies.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/4cDsBog. CME/MOC/NCPD/AAPA/IPCE credit will be available until June 30, 2025.

Candid Conversations on Modern Urothelial Cancer Management: Personalizing Pa...

PVI, PeerView Institute for Medical Education

Chair and Presenters, Andrea Necchi, MD, Matthew D. Galsky, MD, Shilpa Gupta, MD, and Michiel S. van der Heijden, MD, PhD, discuss bladder cancer in this CME/MOC/NCPD/AAPA/IPCE activity titled “Candid Conversations on Modern Urothelial Cancer Management: Personalizing Patient Care Using the Latest Evidence and Innovative Therapeutic Strategies.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/4cDsBog. CME/MOC/NCPD/AAPA/IPCE credit will be available until June 30, 2025.

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PVI, PeerView Institute for Medical Education

Chair and Presenters, Sumanta Kumar Pal, MD, FASCO, Nizar M. Tannir, MD, FACP, and Tian Zhang, MD, MHS, prepared useful Practice Aids pertaining to renal cell carcinoma for this CME/MOC/NCPD/AAPA/IPCE activity titled “A Roadmap for Modern RCC Care: Navigating Personalized Treatment Selection and Sequencing.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/3xgpDpY. CME/MOC/NCPD/AAPA/IPCE credit will be available until July 2, 2025.

A Roadmap for Modern RCC Care: Navigating Personalized Treatment Selection an...

PVI, PeerView Institute for Medical Education

Chair and Presenters, Sumanta Kumar Pal, MD, FASCO, Nizar M. Tannir, MD, FACP, and Tian Zhang, MD, MHS, discuss renal cell carcinoma in this CME/MOC/NCPD/AAPA/IPCE activity titled “A Roadmap for Modern RCC Care: Navigating Personalized Treatment Selection and Sequencing.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/3xgpDpY. CME/MOC/NCPD/AAPA/IPCE credit will be available until July 2, 2025.

Taking a Closer Look at Each Patient: Exploring Novel Biomarker and Imaging S...

PVI, PeerView Institute for Medical Education

Co-Chairs, Amit Bar-Or, MD, FRCPC, and Jiwon Oh, MD, PhD, FRCPC, prepared useful Practice Aids pertaining to multiple sclerosis for this CME/NCPD/CPE/IPCE activity titled “Taking a Closer Look at Each Patient: Exploring Novel Biomarker and Imaging Strategies in MS.” For the full presentation, downloadable Practice Aids, and complete CME/NCPD/CPE/IPCE information, and to apply for credit, please visit us at https://bit.ly/3IyZJQh. CME/NCPD/CPE/IPCE credit will be available until June 29, 2025.

Taking a Closer Look at Each Patient: Exploring Novel Biomarker and Imaging S...

PVI, PeerView Institute for Medical Education

Co-Chairs, Amit Bar-Or, MD, FRCPC, and Jiwon Oh, MD, PhD, FRCPC, discuss multiple sclerosis in this CME/NCPD/CPE/IPCE activity titled “Taking a Closer Look at Each Patient: Exploring Novel Biomarker and Imaging Strategies in MS.” For the full presentation, downloadable Practice Aids, and complete CME/NCPD/CPE/IPCE information, and to apply for credit, please visit us at https://bit.ly/3IyZJQh. CME/NCPD/CPE/IPCE credit will be available until June 29, 2025.

Chair and Presenter, Manish A. Shah, MD, FASCO, Ronan J. Kelly, MD, MBA, FASCO, and Prof. Dr. Markus Moehler, discuss gastric cancer in this CME/MOC/NCPD/AAPA activity titled “Catalysts for Change in Gastric & GEJ Cancer: Digesting New Evidence & Future Directions of Care With Innovative Immunotherapy & Targeted Platforms.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at https://bit.ly/3VHpl55. CME/MOC/NCPD/AAPA credit will be available until July 2, 2025.

Unlocking the Power of Modern Therapeutic Regimens for Prostate Cancer: Exper...

PVI, PeerView Institute for Medical Education

Chair and Presenters, Karim Fizazi, MD, PhD, Pedro C. Barata, MD, MSc, FACP, Kim N. Chi, MD, FRCPC, and Alicia K. Morgans, MD, MPH, discuss prostate cancer in this CME/MOC/NCPD/AAPA/IPCE activity titled “Unlocking the Power of Modern Therapeutic Regimens for Prostate Cancer: Experts Put the Pressure on Key Evidence and Real-World Strategies to Optimize Patient Care.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/3VqHUKU. CME/MOC/NCPD/AAPA/IPCE credit will be available until July 1, 2025.

Precision Tactics in HER2-Positive GI Malignancies: Capitalizing on HER2-Targ...

PVI, PeerView Institute for Medical Education

Chair and Presenters, Yelena Y. Janjigian*, MD, Shubham Pant, MD, and John Strickler, MD, discuss HER2+ GI malignancies in this CME/MOC/NCPD/AAPA/IPCE activity titled “Precision Tactics in HER2-Positive GI Malignancies: Capitalizing on HER2-Targeted Regimens to Improve Outcomes for Gastric/GEJ Cancers, CRC, and BTC.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/49K4Qcb. CME/MOC/NCPD/AAPA/IPCE credit will be available until June 30, 2025.

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PVI, PeerView Institute for Medical Education

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PVI, PeerView Institute for Medical Education

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PVI, PeerView Institute for Medical Education

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Safeguarding Patients With HR+, HER2-, High-Risk, Early Breast Cancer: A Prac...

PVI, PeerView Institute for Medical Education

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Safeguarding Patients With HR+, HER2-, High-Risk, Early Breast Cancer: A Prac...

PVI, PeerView Institute for Medical Education

Chair and Presenters Professor Stephen Johnston, MA, PhD, Patrick Neven, MD, PhD, and Joyce O’Shaughnessy, MD, discuss breast cancer in this CME/MOC/CPD/NCPD/CPE/AAPA activity titled “Safeguarding Patients With HR+, HER2-, High-Risk, Early Breast Cancer: A Practical Roadmap for CDK4/6 Inhibition in the Adjuvant Setting.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/CPD/NCPD/CPE/AAPA information, and to apply for credit, please visit us at https://bit.ly/49HZ5fH. CME/MOC/CPD/NCPD/CPE/AAPA credit will be available until June 21, 2025.

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PVI, PeerView Institute for Medical Education

Chair, Javier Morales, MD, FACP, FACE, discusses Type 2 diabetes in this CME/CE/AAPA activity titled “Cases in the Community: Optimizing Treatment and Considering Weight Management as a Primary Goal in People with T2DM.” For the full presentation, downloadable Practice Aids, and complete CME/CE/AAPA information, and to apply for credit, please visit us at . CME/CE/AAPA credit will be available until June 11, 2025.

Redefining Frontlines in CLL: Key Questions on the Role of CIT, BTKi Standard...

PVI, PeerView Institute for Medical Education

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PVI, PeerView Institute for Medical Education

Co-Chairs, Val J. Lowe, MD, and Cyrus A. Raji, MD, PhD, discuss Alzheimer’s disease in this CME/AAPA activity titled “Alzheimer’s Disease Case Conference: Gearing Up for the Expanding Role of Neuroradiology in Diagnosis and Treatment.” For the full presentation, downloadable Practice Aids, and complete CME/AAPA information, and to apply for credit, please visit us at https://bit.ly/3PvVY25. CME/AAPA credit will be available until June 28, 2025.

Alzheimer’s Disease Case Conference: Gearing Up for the Expanding Role of Neu...

PVI, PeerView Institute for Medical Education

Co-Chairs, Val J. Lowe, MD, and Cyrus A. Raji, MD, PhD, prepared useful Practice Aids pertaining to Alzheimer’s disease for this CME/AAPA activity titled “Alzheimer’s Disease Case Conference: Gearing Up for the Expanding Role of Neuroradiology in Diagnosis and Treatment.” For the full presentation, downloadable Practice Aids, and complete CME/AAPA information, and to apply for credit, please visit us at https://bit.ly/3PvVY25. CME/AAPA credit will be available until June 28, 2025.

Adapting HIV Treatment for People With Substance Use Disorder

PVI, PeerView Institute for Medical Education

Chair, Monica Gandhi, MD, MPH, prepared useful Practice Aids pertaining to HIV for this CME/MOC/CE/AAPA activity titled “Adapting HIV Treatment for People With Substance Use Disorder.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/CE/AAPA information, and to apply for credit, please visit us at https://bit.ly/49hgPxT. CME/MOC/CE/AAPA credit will be available until June 4, 2025.

Adapting HIV Treatment for People With Substance Use Disorder

PVI, PeerView Institute for Medical Education

Aligning Clinical Practice With Emerging Evidence: Navigating the Rapidly Evo...

PVI, PeerView Institute for Medical Education

Chair, Carla M. Nester, MD, MSA, FASN, discusses glomerular kidney disease in this CME activity titled “Aligning Clinical Practice With Emerging Evidence: Navigating the Rapidly Evolving Landscape of Glomerular Kidney Disease Management.” For the full presentation, downloadable Practice Aids, and complete CME information, and to apply for credit, please visit us at https://bit.ly/3wJPTs1. CME credit will be available until June 4, 2025.

Experts vs AI: Who Is Better at Monitoring and Treating MASLD and MASH?

PVI, PeerView Institute for Medical Education

Chair and Presenter Rohit Loomba, MD, MHSc, and Alina M. Allen, MD, MS, discuss metabolic dysfunction–associated steatohepatitis in this CME activity titled “Experts vs AI: Who Is Better at Monitoring and Treating MASLD and MASH?.” For the full presentation, downloadable Practice Aids, and complete CME information, and to apply for credit, please visit us at https://bit.ly/3O53xMy. CME credit will be available until June 19, 2025.

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PVI, PeerView Institute for Medical Education

Co-Chairs, Prof. Mohamad Mohty, MD, PhD, and Caitlin Costello, MD, discuss refractory multiple myeloma in this CME/CPD activity titled “Five Steps for Integrating BCMA Bispecific Innovations: From Clinical Data to Clinical Practice in RRMM.” For the full presentation, downloadable Practice Aids, and complete CME/CPD information, and to apply for credit, please visit us at https://bit.ly/3UFL0dt. CME/CPD credit will be available until 5 June 2025.

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PVI, PeerView Institute for Medical Education

Co-Chairs, Doreen J. Addrizzo-Harris, MD, and Cedric "Jamie" Rutland, MD, discuss non-cystic fibrosis bronchiectasis in this CME/MOC/AAPA activity titled “Stories Behind the Science in Non-Cystic Fibrosis Bronchiectasis: Understanding Disease Burden, Diagnosing Early, and Looking Toward New Management Options.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/AAPA information, and to apply for credit, please visit us at https://bit.ly/3KlxjL9. CME/MOC/AAPA credit will be available until June 19, 2025.

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PVI, PeerView Institute for Medical Education

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Bridging the Gap to Improved Outcomes in Non-Cystic Fibrosis Bronchiectasis: ...

PVI, PeerView Institute for Medical Education

Co-Chairs, Brett Elicker, MD, and David E. Griffith, MD, ATSF, ACCP, OFRSM, prepared useful Practice Aids pertaining to non-cystic fibrosis bronchiectasis for this CME/MOC activity titled “Bridging the Gap to Improved Outcomes in Non-Cystic Fibrosis Bronchiectasis: Ensuring Prompt Diagnosis Through Accurate Interpretation of CT Imaging.” For the full presentation, downloadable Practice Aids, and complete CME/MOC information, and to apply for credit, please visit us at https://bit.ly/48WUULu. CME/MOC credit will be available until June 4, 2025.

SENSORY NEEDS B.SC. NURSING SEMESTER II.

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Breast cancer: Post menopausal endocrine therapy

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Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options. Diagnosis and Staging The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells. Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions. Treatment Options Endocrine Therapy Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include: Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events. Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen. Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops. Combination Therapies Combining endocrine therapy with other treatments enhances efficacy. Examples include: Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer. Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors. Chemotherapy Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.

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