Marieb. E.N. (2001) explains that gonads begin to form until the eighth week of embryonic development. During the early stages of human development, embryonic reproductive structures of males and females are alike and said to be in indifferent stage.
The presence of male and female structures depends on the presence of testosterone.
Any intervention with the normal pattern of sex hormone production in the embryo results in strange abnormalities.
Puberty is the period of life, generally between the ages of 10 to 15 years old, when the reproductive -organs grow to their adult size and become functional under the influence of rising levels of gonadal hormones (testosterone on males and estrogen on females).
In males, as they reach the age of 13, puberty is characterized by the increased in the size of the reproductive organs followed by the appearance of hair in the public area, axillary, and face.
In females, the budding of their breast usually occurring at the age of 11. Menarche is the first menstrual of females which happens two years after the start of puberty.
Freud's psychoanalytic theory of developmentZat Tero Jr.
Sigmund Freud: Freud developed the psychoanalytic theory of personality development, which argued that personality is formed through conflicts among three fundamental structures of the human mind: the id, ego, and superego.
Marieb. E.N. (2001) explains that gonads begin to form until the eighth week of embryonic development. During the early stages of human development, embryonic reproductive structures of males and females are alike and said to be in indifferent stage.
The presence of male and female structures depends on the presence of testosterone.
Any intervention with the normal pattern of sex hormone production in the embryo results in strange abnormalities.
Puberty is the period of life, generally between the ages of 10 to 15 years old, when the reproductive -organs grow to their adult size and become functional under the influence of rising levels of gonadal hormones (testosterone on males and estrogen on females).
In males, as they reach the age of 13, puberty is characterized by the increased in the size of the reproductive organs followed by the appearance of hair in the public area, axillary, and face.
In females, the budding of their breast usually occurring at the age of 11. Menarche is the first menstrual of females which happens two years after the start of puberty.
Freud's psychoanalytic theory of developmentZat Tero Jr.
Sigmund Freud: Freud developed the psychoanalytic theory of personality development, which argued that personality is formed through conflicts among three fundamental structures of the human mind: the id, ego, and superego.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
2. 1. During the oral stage, the infant's primary source of
interaction occurs through the mouth, so the rooting
and sucking reflex is especially important. The mouth is
vital for eating, and the infant derives pleasure from
oral stimulation through gratifying activities such as
tasting and sucking.
The Oral Stage
3. The Anal Stage
2. During the anal stage, Freud
believed that the primary focus of
the libido was on controlling
bladder and bowel movements. The
major conflict at this stage is toilet
training—the child has to learn to
control their bodily needs.
Developing this control leads to a
sense of accomplishment and
independence.
AGE RANGE: 1-3 YEARS OLD
4. The Phallic Stage
Freud suggested that during the phallic
stage, the primary focus of the libido is on
the genitals. At this age, children also begin
to discover the differences between males
and females.
5. The Latent Part
The latent period is a time of exploration in which the sexual
energy is repressed or dormant. This energy is still present, but it
is sublimated into other areas such as intellectual pursuits and
social interactions. This stage is important in the development of
social and communication skills and self-confidence.
6. The Genital Stage
The onset of puberty causes the libido to become active once again.
During the final stage of psychosexual development, the individual
develops a strong sexual interest in the opposite sex. This stage begins
during puberty but last throughout the rest of a person's life.
Where in earlier stages the focus was solely on individual needs, interest in
the welfare of others grows during this stage. The goal of this stage is to
establish a balance between the various life areas.
7.
8. Male Reproductive System
a. 4. Testis – is the most important part of male reproductive organ. It is the source
of
Spermatozoa (male germ cell)
b. Scrotum – it is a sac of skin where the two testes are enveloped; directly below and
outside of the abdomen.
c. 5. Prostate glands – it is a gland that carries out both urine and seminal fluid. It is
connected by sperm ducts from sperm ducts joining into single tube called urethra.
9. Female Reproductive System
1. Ovary – It is a pair of small, oval organs which produces ova (ovum; female germ
cells).
Thousands of ova will mature and will be taken up to the fallopian tube through the
uterus by the time of puberty.
2. 6. Fallopian Tube – are pair of thin tubes that leads from ovaries to the uterus.
3. Uterus – (womb) it is a hollow pear-shaped elastic muscular structure where
fertilized
10. 7. Erogenous Zone
These are part of the body that particularly sensitive to touch, pressure and vibration
which contributes to sexual arousal. Identifying erogenous zone (“hot spots”) gives different
reaction and effect to a person. For one, these could bring sexual satisfaction, also, improves
sexual health and stimulating different spots may produce different reaction to the body. Female
and male erogenous zone are reproductive organ (vagina, penis, scrotum & clitoris), mouth
Physiological
Aspects of Sexual
Excitement
11. Phases of Sexual Response
Although, erogenous zone brings us to sexual arousal which is unique to
each individual, people
sharessame basic aspects of sexual responsiveness. According to Johnson
& Master (1966), sexual
response follows a regular pattern consisting of four (4) phases: arousal,
plateau, orgasm and
resolution.
12. The arousal phase is a subjective sense of sexual pleasure. The physiological sign in
males is penile tumescence (erection) and vasocongestion to female leads to vaginal
lubrication and nipple erection.
The plateau phase is a brief period of time before the orgasm. It is the body’s
preparation for orgasm
The orgasm phase is an intense, highly pleasurable experience. When this phase is
reached, rhythmic muscular contractions occur in the genitals. In male, the contractions expel
semen, a fluid containing sperm, a process called ejaculation. For women and men, breathing
and heart rates reach maximum.
Last stage of sexual arousal, the resolution stage where the decrease of arousal
(particularly in male) happens. Genitals resume their unaroused state and shape; blood
pressure, breathing and heart rate return to normal.
13. Sexual behavior transcends in different forms. It may be
influenced by not only the basic
physiological aspect of sexuality but also by different
expectations, attitudes, beliefs and state of
medical and biological knowledge. It made sexual behavior take a
more diverse forms such as
Diversity of Sexual Behavior
14. 10. What is sexual orientation?
Sexual orientation is about who you’re
attracted to and want to have relationships
with. Sexual orientations include gay,
lesbian, straight, bisexual, and asexual.
15. Sexual orientation is different from gender
and gender identity.
Sexual orientation is about who you’re
attracted to and who you feel drawn to
romantically, emotionally, and sexually. It’s
different than gender identity. Gender
identity isn’t about who you’re attracted to,
but about who you ARE — male, female,
genderqueer, etc.
16. 11. Heterosexuality
Is a sexual attraction and behavior directed to
other sex. More than male-female
intercourse, it involves kissing, petting, caressing,
massaging and other form of sexual
activities.
17. Homosexuality and Bisexuality
Homosexualsisa romantic and/or sexual attraction
between members of same sex.
Bisexuals are person who can be romantically or
sexually attracted to same sex and the other
sex. Some male homosexuals prefer the term Gay
and some female homosexual prefer the
term Lesbian. Gays and Lesbian as preference for a
terminology refer not only to their sexual
preference but also as Gender preference. These by
which refer to a broader array of attitudes
and lifestyle of the individual than the sexuality
itself.
18. Transsexuality
These are people who believed they were born with the
body of the other gender. Men
transsexuals believe that they are men in a women’s
body and women transsexuals believe that
they are women in a men’s body. Transsexuals
sometimes seek sex exchange operations,
which undergo several steps such as intensive sexual
19. What does queer mean?
The term queer can include a variety of
sexual identities and gender identities that
are anything other than straight and
cisgender.
20. 13. What’s asexuality?
People who identify as asexual don’t really feel sexual attraction
towards anyone. They may think other people are physically
attractive, or they may want to be in romantic relationships with
people — but they’re not interested in having sex or doing sexual
things with other people. Asexual people sometimes use the word
“ace” for short.