Ultrasound image presentation Tim Hartshorne
•Download as PPTX, PDF•
1 like•930 views
Tim Hartshorne opened the AAA CST Information & Support Day in London on April 27th 2018. Questions were raised about what constitutes an acceptable ultrasound image and accurate aortic diameter measurement, and whether all CSTs provide the same level of feedback on image quality and quality assurance. While automated peer review seems promising, it is not currently suitable for AAA screening due to challenges in analyzing abdominal ultrasound images and confirming accurate measurements. Alternative ways of assessing sonographer performance using scatter plots and Bland-Altman plots of longitudinal and transverse diameter measurements were presented.
Report
Share
Report
Share
Recommended
Quality Assurance Programme in Computed Tomography
Introduction to Computed Tomography
Basic description of the components of a CT System
Introduction to Quality Assurance
Quality Assurance and Quality Control Tests in Computed Tomography base on frequency
Objective of QA/QC Test
Igrt And Resp Gating Final Version
1) IGRT uses cone beam CT (CBCT) imaging to improve patient positioning accuracy and account for interfraction motion, allowing for dose escalation and hypofractionated treatments.
2) Respiratory gating uses external surrogates and binning to characterize tumor motion over the respiratory cycle and gate treatment to specific phases to reduce motion-induced targeting errors.
3) The combination of IGRT and respiratory gating can help oncologists see and hit moving tumors, enabling safer dose escalation for treatments like SBRT.
Ct scan
CT-SCAN provides concise summaries of medical documents. This document discusses the history and evolution of computed tomography (CT) scanning technology. It begins with definitions of CT scanning and diagrams of early CT scanner designs. It then summarizes the key developments, including the invention of CT scanning by Godfrey Hounsfield in 1971, the installation of the first CT prototype, and improvements in processing time. The document outlines the generations of CT scanners from first to fifth generation and describes advances in multi-slice and multi-detector array technologies. It concludes with examples of clinical applications and cases imaged with various CT techniques.
Image guided radiation therapy (2011)
Image Guided Radiation Therapy (IGRT) uses imaging technologies to reduce uncertainties in radiation therapy delivery and improve targeting accuracy. IGRT involves acquiring images of the treatment area to capture position and guide corrections. Technologies include 2D kV/MV imaging, 2.5D tomotherapy, and 3D kV-CBCT and MVCT. Future directions include 4D imaging during treatment and combined MR-Linac systems. The clinic plans to implement IGRT starting with basic 2D/3D CBCT capabilities and work towards standardized protocols, automated corrections, and quality assurance programs.
Image Guided Radiotherapy
1. Dr. Sheetal R Kashid presented on the use of IGRT for head and neck cancers and central nervous system tumors at TMH.
2. IGRT uses image guidance to precisely position patients and correct for setup errors, allowing for accurate radiation delivery while minimizing dose to surrounding healthy tissues.
3. At TMH, IGRT is performed using CBCT, EPID, and offline protocols to correct for systematic and random errors in head and neck and neuro-oncology patients.
Radiomics Analysis of Pulmonary Nodules in Low Dose CT for Early Detection of...
Purpose: To predict the histopathologic subtypes with poor surgery prognosis in early stage lung adenocarcinomas using CT and PET radiomics.
Methods: We retrospectively enrolled 53 patients with stage I lung adenocarcinoma who underwent both diagnostic CT and 18F-fluorodeoxyglucose (FDG) PET/CT before complete surgical resection of the tumors. Tumor segmentation was manually contoured by a physician on both the diagnostic CT and the attenuation CT of PET/CT.A total of 170 radiomics features were extracted on both PET and CT images to design predictive models for two histopathologic endpoints: (1) tumors with solid or micropapillary predominant subtype (aggressiveness), and (2) tumors with micropapillary component more than 5% (MIP5). We used least absolute shrinkage and selection operator (LASSO) as a model building method coupled with a class separability feature selection (CSFS) method. For an unbiased model estimate, a 10-fold cross validation approach was used. The area under the curve (AUC) and prediction accuracy were employed to evaluate the performance of the model. P-values were computed using Wilcoxon rank-sum test.
Results: Of the 53 patients, 9 and 15 had tumors with aggressiveness and MIP5, respectively. For both endpoints, LASSO models with two PET radiomics features achieved the best performance. For aggressiveness, the LASSO model with PET Cluster Shade and PET 2D Variance resulted in 77.6±2.3% accuracy and 0.71±0.02 AUC (P = 0.011). For MIP5, the LASSO model with PET Eccentricity and PET Cluster Shade resulted in 69.6±3.1% accuracy and 0.68±0.04 AUC (P=0.014). The PET Cluster Shade was commonly selected in both models. Cluster shade is a texture feature that measures the skewness of the co-occurrence matrix. Higher PET cluster shade predicted that the tumor was more aggressive and more likely MIP5.
Conclusion: We showed that PET/CT radiomics features can predict tumor aggressiveness.
Funding Support, Disclosures, and Conflict of Interest: This work was supported in part by the National Cancer Institute Grants R01CA172638.
Lior_Computed Tomography Angiography a Review and Technical Update 2016
This document discusses computed tomography angiography (CTA) and provides an overview of its basic principles and technical developments. It explains that CTA involves acquiring a high-resolution volumetric CT data set during peak arterial contrast enhancement and using image post-processing techniques. The principles of CTA have remained the same but technical advances have expanded its capabilities. These include improvements in CT scanner hardware like x-ray tubes and detectors that have allowed faster, higher quality imaging. Understanding contrast medium dynamics and optimizing injection protocols based on injection rate and duration is also important for achieving sufficient arterial enhancement.
4D-CBCT (Symmetry) - a useful tool to verify and treat traditional ITV withou...
4D-CBCT is latest software gadget in field of radiation oncology. It will calculate breathing movement during treatment of lung cancer and help in delineate the target better.
This presentation will convince you that even if you do not have 4D-CT simulation, you can confidently use 4D-CBCT at optimal level.
Recommended
Quality Assurance Programme in Computed Tomography
Introduction to Computed Tomography
Basic description of the components of a CT System
Introduction to Quality Assurance
Quality Assurance and Quality Control Tests in Computed Tomography base on frequency
Objective of QA/QC Test
Igrt And Resp Gating Final Version
1) IGRT uses cone beam CT (CBCT) imaging to improve patient positioning accuracy and account for interfraction motion, allowing for dose escalation and hypofractionated treatments.
2) Respiratory gating uses external surrogates and binning to characterize tumor motion over the respiratory cycle and gate treatment to specific phases to reduce motion-induced targeting errors.
3) The combination of IGRT and respiratory gating can help oncologists see and hit moving tumors, enabling safer dose escalation for treatments like SBRT.
Ct scan
CT-SCAN provides concise summaries of medical documents. This document discusses the history and evolution of computed tomography (CT) scanning technology. It begins with definitions of CT scanning and diagrams of early CT scanner designs. It then summarizes the key developments, including the invention of CT scanning by Godfrey Hounsfield in 1971, the installation of the first CT prototype, and improvements in processing time. The document outlines the generations of CT scanners from first to fifth generation and describes advances in multi-slice and multi-detector array technologies. It concludes with examples of clinical applications and cases imaged with various CT techniques.
Image guided radiation therapy (2011)
Image Guided Radiation Therapy (IGRT) uses imaging technologies to reduce uncertainties in radiation therapy delivery and improve targeting accuracy. IGRT involves acquiring images of the treatment area to capture position and guide corrections. Technologies include 2D kV/MV imaging, 2.5D tomotherapy, and 3D kV-CBCT and MVCT. Future directions include 4D imaging during treatment and combined MR-Linac systems. The clinic plans to implement IGRT starting with basic 2D/3D CBCT capabilities and work towards standardized protocols, automated corrections, and quality assurance programs.
Image Guided Radiotherapy
1. Dr. Sheetal R Kashid presented on the use of IGRT for head and neck cancers and central nervous system tumors at TMH.
2. IGRT uses image guidance to precisely position patients and correct for setup errors, allowing for accurate radiation delivery while minimizing dose to surrounding healthy tissues.
3. At TMH, IGRT is performed using CBCT, EPID, and offline protocols to correct for systematic and random errors in head and neck and neuro-oncology patients.
Radiomics Analysis of Pulmonary Nodules in Low Dose CT for Early Detection of...
Purpose: To predict the histopathologic subtypes with poor surgery prognosis in early stage lung adenocarcinomas using CT and PET radiomics.
Methods: We retrospectively enrolled 53 patients with stage I lung adenocarcinoma who underwent both diagnostic CT and 18F-fluorodeoxyglucose (FDG) PET/CT before complete surgical resection of the tumors. Tumor segmentation was manually contoured by a physician on both the diagnostic CT and the attenuation CT of PET/CT.A total of 170 radiomics features were extracted on both PET and CT images to design predictive models for two histopathologic endpoints: (1) tumors with solid or micropapillary predominant subtype (aggressiveness), and (2) tumors with micropapillary component more than 5% (MIP5). We used least absolute shrinkage and selection operator (LASSO) as a model building method coupled with a class separability feature selection (CSFS) method. For an unbiased model estimate, a 10-fold cross validation approach was used. The area under the curve (AUC) and prediction accuracy were employed to evaluate the performance of the model. P-values were computed using Wilcoxon rank-sum test.
Results: Of the 53 patients, 9 and 15 had tumors with aggressiveness and MIP5, respectively. For both endpoints, LASSO models with two PET radiomics features achieved the best performance. For aggressiveness, the LASSO model with PET Cluster Shade and PET 2D Variance resulted in 77.6±2.3% accuracy and 0.71±0.02 AUC (P = 0.011). For MIP5, the LASSO model with PET Eccentricity and PET Cluster Shade resulted in 69.6±3.1% accuracy and 0.68±0.04 AUC (P=0.014). The PET Cluster Shade was commonly selected in both models. Cluster shade is a texture feature that measures the skewness of the co-occurrence matrix. Higher PET cluster shade predicted that the tumor was more aggressive and more likely MIP5.
Conclusion: We showed that PET/CT radiomics features can predict tumor aggressiveness.
Funding Support, Disclosures, and Conflict of Interest: This work was supported in part by the National Cancer Institute Grants R01CA172638.
Lior_Computed Tomography Angiography a Review and Technical Update 2016
This document discusses computed tomography angiography (CTA) and provides an overview of its basic principles and technical developments. It explains that CTA involves acquiring a high-resolution volumetric CT data set during peak arterial contrast enhancement and using image post-processing techniques. The principles of CTA have remained the same but technical advances have expanded its capabilities. These include improvements in CT scanner hardware like x-ray tubes and detectors that have allowed faster, higher quality imaging. Understanding contrast medium dynamics and optimizing injection protocols based on injection rate and duration is also important for achieving sufficient arterial enhancement.
4D-CBCT (Symmetry) - a useful tool to verify and treat traditional ITV withou...
4D-CBCT is latest software gadget in field of radiation oncology. It will calculate breathing movement during treatment of lung cancer and help in delineate the target better.
This presentation will convince you that even if you do not have 4D-CT simulation, you can confidently use 4D-CBCT at optimal level.
Towards diagnosis of rotator cuff tears in 3-D MRI using 3-D convolutional ne...
Towards diagnosis of rotator cuff tears in 3-D MRI using 3-D convolutional neural networks. Paper presented at the Workshop on Computational Biology at the International Conference on Machine Learning, Long Beach, USA, 2019.
7200 35328
This document provides an overview of CT simulation components and processes. It discusses the key elements of a CT simulator, including the CT scanner components like bore size and image quality, virtual simulation software features like contouring and image display, and other essentials like laser positioning and DICOM connectivity. CT simulation has advanced radiation therapy planning by providing detailed volumetric patient images to design customized treatment plans while reducing dose to healthy tissues.
Subjective assignment 2
The document discusses measurement systems and displacement transducers. It defines measurement and outlines the objectives of instrumentation. It describes the general configuration of measurement systems and their functional elements. It also discusses the static and dynamic performance characteristics of measuring instruments, sources of error, and classification and elimination of errors. Finally, it examines various transducers used to measure displacement, including piezoelectric, inductive, capacitive, resistance, ionization and photoelectric transducers.
1.2
This document discusses measurement and uncertainties in physics. It introduces standard SI units which are used for measurement in most countries. Fundamental quantities like length, time and mass cannot be measured in simpler terms and form the basis of other derived units. Accuracy refers to how close a measurement is to the accepted value, while precision refers to the agreement between multiple measurements. Random and systematic errors can affect measurements and need to be accounted for using techniques like taking multiple readings and estimating uncertainties. Graphs are useful for analyzing experimental data and determining relationships between variables.
Individually Optimized Contrast-Enhanced 4D-CT for Radiotherapy Simulation in...
To develop an individually optimized contrast-enhanced (CE) 4D-CT for radiotherapy simulation in pancreatic ductal adenocarcinomas (PDA).
http://scitation.aip.org/content/aapm/journal/medphys/43/6/10.1118/1.4958261
4 D Igrt
4D-IGRT involves accounting for tumor motion during radiation therapy delivery. It uses 4D computed tomography (4D CT) imaging, which captures tumor position at different respiratory phases. This allows delineation of an internal target volume (ITV) that encompasses the full range of tumor motion. Treatment can then be delivered over the entire respiratory cycle or gated to a specific phase such as end-exhalation using respiratory tracking systems. The goal is to ensure accurate radiation delivery while minimizing doses to surrounding healthy tissues.
Assessment of Femoral Tunnel Placement in ACL Reconstruction
This study reviews the literature on tunnel placement in anterior cruciate ligament reconstruction, and assess the ability of experienced physicians and surgeons to evaluate the tunnel position using x-rays.
Ct urinary system in radiology
CT scans use X-rays and computer calculations to produce detailed cross-sectional images of the body's internal structures. A CT scan of the urinary system can detect tumors, masses, stones, or cysts. The test is performed in a radiology department where the patient lies on a table that slides into a CT scanner. Dye may be injected into the patient's vein to enhance image quality. CT scans can distinguish between solid and liquid tissues and provide valuable information for examining kidney tumors and other abnormalities of the urinary tract. Risks of CT scanning are generally low but may include minor reactions to dye in rare cases more severe complications.
Fundación EPIC _ "TAC para planificar el procedimiento e impresión 3D: es rea...
This document discusses the use of CT scans and 3D printing to characterize the left atrial appendage (LAA) anatomy prior to LAA occlusion procedures. It notes that the complex structure of the LAA makes sizing and implantation of closure devices challenging when relying solely on 2D TEE imaging. The document outlines how pre-procedural CT scans can provide detailed information on LAA dimensions, bends, lobes and surrounding structures to aid in device selection and planning fluoroscopy angles. It also discusses how 3D printing of the LAA can allow for rehearsal of the procedure and sizing agreement with implanted devices in over 95% of cases compared to 45% when using TEE alone.
Reject film Analysis
The document discusses reject film analysis in radiology. Reject film analysis measures actual quality against standards and identifies necessary corrective actions. It aims to minimize patient exposure, reduce costs, improve throughput and image quality. Common reasons for rejected films include positioning errors, under/over exposure, and patient movement. Analyzing reject films helps address equipment issues and identifies areas for improved training.
CST presentation Colin Nice Tim Hartshorne
This document discusses developing a standardized process for assessing image quality in abdominal aortic aneurysm ultrasound screening. It proposes a 10-point scoring system and benchmarking exercise with 50 cases to test reliability and reproducibility. Feedback from screeners noted optimal depth shows the aorta occupying 15-25% of the image and calliper placement deviation less than 10 degrees from perpendicular as thresholds. Next steps include applying for approvals to conduct a larger study comparing this criteria to an alternative 10-point scale with multiple screeners. The goal is to improve quality assurance of ultrasound images in the screening program.
Survival report of 76 breast cancer patients under three different treatments
Aim of the Project- An application of the Kaplan-Meier estimator, Lifetable Analysis and a clinical data, the survival time of 76 breast cancer patients categorized under three different treatments, which is presented with respected lifetables along with survival and hazard function for comparison.
Statistical techniques Used- Kaplan-Meier estimator, Lifetable Analysis
Software Used- SAS, Excel
Do we need new definitions for CTO PCI
CTO definitions: Do we need a new consensus?
Gerald S. Werner, Darmstadt, Germany
10th Experts „Live“ CTO Workshop - Day1
Biostat_Chapter6_Part3.pdf Bio Statistics
This document provides an overview of the Kaplan-Meier estimator for survival analysis and includes two examples. It defines the Kaplan-Meier estimator and assumptions. Example 1 derives the Kaplan-Meier estimate from study data on time to death and finds the probability of surviving past 10 years is 85%, the minimum years for 75% survival is 13, and median survival is 18 years. Example 2 estimates survival functions for a clinical trial comparing a treatment to placebo and shows higher survival for the treatment group.
Radiomics and Deep Learning for Lung Cancer Screening
The document summarizes research on using radiomics and deep learning approaches for lung cancer screening. It describes:
1) Using radiomic features like shape, texture, and intensity from lung nodules on CT scans and an SVM-LASSO model to classify nodules with 87.9% sensitivity and 78.2% specificity, outperforming the Lung-RADS system.
2) A deep learning model developed for a Kaggle competition that achieved 67.4% accuracy on nodule classification but only ranked 99th due to overfitting issues without enough data.
3) Future work could integrate quantification of nodule characteristics like spiculation with plasma biomarkers to improve diagnostic accuracy.
Cyto 2015 Forensic Flow Cytometry Tutorial
Troubleshooting flow cytometry data. (Please excuse any formatting issues that arose in the slideshare translation of this powerpoint presentation.)
4dct (2012)
Four Dimensional Computed Tomography in Radiation Therapy - basic principles and implementation in a radiation oncology setting
Measurement system analysis Presentation.ppt
Measurement system analysis, Quality and Operation Module.
Digital Image Processing Assessment in Multi Slice CT Angiogram using Liner, ...
Nowadays with heart diseases most of peoples are dying lock process to find problem agile fashion in remote areas. In this research help to peoples who are staying remote also to find problem in heart on which location and how much problem to near and finally gives best analysis methodology for automated analysis for MultiSlice CT Angiogram images. Multi slice CT scanner is used to identify heart disease. Multi-detector CT is considered convenient and reliable non-invasive imaging modality for assessment of human angiogram 3D images. Automatic hart segmentation from Computed Tomography (CT) is highly demanded. Accurate hart segmentation is a crucial for computer-aided heart disease diagnosis and treatment planning. After segmentation and future extraction then identify whether the patient angiogram waveform has disease or not. For that, Support Vector Machine method is used to confirm the presence of disease. Neural Networks can solve different types of nonlinear problems in image classification and retrieval process. After that majorly focus on research learning methodologies for improve performance of the Multi Slice CT Angiogram images. So, in this research is summarizing the problem with liner of RBF neural network, Non-Liner SVM and RBF NN with liner and non-liner. Final, RBF NN with liner and non-liner provided more value and proved as best compare with other existing methodologies. This methodology consumes less time for both learning as well as testing comparatively than any other methods like back propagation. This issue drastically improves the estimation efficiency and accuracy for real time 128, 256 slices CT scan angiogram images.
NHS screening leaflet short urls and qr codes PDF
This document provides short URLs and QR codes for digital information leaflets about various NHS screening programs in the UK, including antenatal and newborn, AAA, bowel cancer, breast cancer, cervical cancer, and diabetic eye screening. Short URLs and QR codes are included to easily direct people to online collections of digital information leaflets for each screening program through mobile devices.
NHS screening leaflet short urls and qr codes
This document provides short URLs and QR codes for digital information leaflets about various NHS screening programs in the UK, including antenatal and newborn, AAA, bowel cancer, breast cancer, cervical cancer, and diabetic eye screening. Short URLs and QR codes are included to easily direct people to online collections of digital information leaflets for each screening program through mobile devices.
More Related Content
Similar to Ultrasound image presentation Tim Hartshorne
Towards diagnosis of rotator cuff tears in 3-D MRI using 3-D convolutional ne...
Towards diagnosis of rotator cuff tears in 3-D MRI using 3-D convolutional neural networks. Paper presented at the Workshop on Computational Biology at the International Conference on Machine Learning, Long Beach, USA, 2019.
7200 35328
This document provides an overview of CT simulation components and processes. It discusses the key elements of a CT simulator, including the CT scanner components like bore size and image quality, virtual simulation software features like contouring and image display, and other essentials like laser positioning and DICOM connectivity. CT simulation has advanced radiation therapy planning by providing detailed volumetric patient images to design customized treatment plans while reducing dose to healthy tissues.
Subjective assignment 2
The document discusses measurement systems and displacement transducers. It defines measurement and outlines the objectives of instrumentation. It describes the general configuration of measurement systems and their functional elements. It also discusses the static and dynamic performance characteristics of measuring instruments, sources of error, and classification and elimination of errors. Finally, it examines various transducers used to measure displacement, including piezoelectric, inductive, capacitive, resistance, ionization and photoelectric transducers.
1.2
This document discusses measurement and uncertainties in physics. It introduces standard SI units which are used for measurement in most countries. Fundamental quantities like length, time and mass cannot be measured in simpler terms and form the basis of other derived units. Accuracy refers to how close a measurement is to the accepted value, while precision refers to the agreement between multiple measurements. Random and systematic errors can affect measurements and need to be accounted for using techniques like taking multiple readings and estimating uncertainties. Graphs are useful for analyzing experimental data and determining relationships between variables.
Individually Optimized Contrast-Enhanced 4D-CT for Radiotherapy Simulation in...
To develop an individually optimized contrast-enhanced (CE) 4D-CT for radiotherapy simulation in pancreatic ductal adenocarcinomas (PDA).
http://scitation.aip.org/content/aapm/journal/medphys/43/6/10.1118/1.4958261
4 D Igrt
4D-IGRT involves accounting for tumor motion during radiation therapy delivery. It uses 4D computed tomography (4D CT) imaging, which captures tumor position at different respiratory phases. This allows delineation of an internal target volume (ITV) that encompasses the full range of tumor motion. Treatment can then be delivered over the entire respiratory cycle or gated to a specific phase such as end-exhalation using respiratory tracking systems. The goal is to ensure accurate radiation delivery while minimizing doses to surrounding healthy tissues.
Assessment of Femoral Tunnel Placement in ACL Reconstruction
This study reviews the literature on tunnel placement in anterior cruciate ligament reconstruction, and assess the ability of experienced physicians and surgeons to evaluate the tunnel position using x-rays.
Ct urinary system in radiology
CT scans use X-rays and computer calculations to produce detailed cross-sectional images of the body's internal structures. A CT scan of the urinary system can detect tumors, masses, stones, or cysts. The test is performed in a radiology department where the patient lies on a table that slides into a CT scanner. Dye may be injected into the patient's vein to enhance image quality. CT scans can distinguish between solid and liquid tissues and provide valuable information for examining kidney tumors and other abnormalities of the urinary tract. Risks of CT scanning are generally low but may include minor reactions to dye in rare cases more severe complications.
Fundación EPIC _ "TAC para planificar el procedimiento e impresión 3D: es rea...
This document discusses the use of CT scans and 3D printing to characterize the left atrial appendage (LAA) anatomy prior to LAA occlusion procedures. It notes that the complex structure of the LAA makes sizing and implantation of closure devices challenging when relying solely on 2D TEE imaging. The document outlines how pre-procedural CT scans can provide detailed information on LAA dimensions, bends, lobes and surrounding structures to aid in device selection and planning fluoroscopy angles. It also discusses how 3D printing of the LAA can allow for rehearsal of the procedure and sizing agreement with implanted devices in over 95% of cases compared to 45% when using TEE alone.
Reject film Analysis
The document discusses reject film analysis in radiology. Reject film analysis measures actual quality against standards and identifies necessary corrective actions. It aims to minimize patient exposure, reduce costs, improve throughput and image quality. Common reasons for rejected films include positioning errors, under/over exposure, and patient movement. Analyzing reject films helps address equipment issues and identifies areas for improved training.
CST presentation Colin Nice Tim Hartshorne
This document discusses developing a standardized process for assessing image quality in abdominal aortic aneurysm ultrasound screening. It proposes a 10-point scoring system and benchmarking exercise with 50 cases to test reliability and reproducibility. Feedback from screeners noted optimal depth shows the aorta occupying 15-25% of the image and calliper placement deviation less than 10 degrees from perpendicular as thresholds. Next steps include applying for approvals to conduct a larger study comparing this criteria to an alternative 10-point scale with multiple screeners. The goal is to improve quality assurance of ultrasound images in the screening program.
Survival report of 76 breast cancer patients under three different treatments
Aim of the Project- An application of the Kaplan-Meier estimator, Lifetable Analysis and a clinical data, the survival time of 76 breast cancer patients categorized under three different treatments, which is presented with respected lifetables along with survival and hazard function for comparison.
Statistical techniques Used- Kaplan-Meier estimator, Lifetable Analysis
Software Used- SAS, Excel
Do we need new definitions for CTO PCI
CTO definitions: Do we need a new consensus?
Gerald S. Werner, Darmstadt, Germany
10th Experts „Live“ CTO Workshop - Day1
Biostat_Chapter6_Part3.pdf Bio Statistics
This document provides an overview of the Kaplan-Meier estimator for survival analysis and includes two examples. It defines the Kaplan-Meier estimator and assumptions. Example 1 derives the Kaplan-Meier estimate from study data on time to death and finds the probability of surviving past 10 years is 85%, the minimum years for 75% survival is 13, and median survival is 18 years. Example 2 estimates survival functions for a clinical trial comparing a treatment to placebo and shows higher survival for the treatment group.
Radiomics and Deep Learning for Lung Cancer Screening
The document summarizes research on using radiomics and deep learning approaches for lung cancer screening. It describes:
1) Using radiomic features like shape, texture, and intensity from lung nodules on CT scans and an SVM-LASSO model to classify nodules with 87.9% sensitivity and 78.2% specificity, outperforming the Lung-RADS system.
2) A deep learning model developed for a Kaggle competition that achieved 67.4% accuracy on nodule classification but only ranked 99th due to overfitting issues without enough data.
3) Future work could integrate quantification of nodule characteristics like spiculation with plasma biomarkers to improve diagnostic accuracy.
Cyto 2015 Forensic Flow Cytometry Tutorial
Troubleshooting flow cytometry data. (Please excuse any formatting issues that arose in the slideshare translation of this powerpoint presentation.)
4dct (2012)
Four Dimensional Computed Tomography in Radiation Therapy - basic principles and implementation in a radiation oncology setting
Measurement system analysis Presentation.ppt
Measurement system analysis, Quality and Operation Module.
Digital Image Processing Assessment in Multi Slice CT Angiogram using Liner, ...
Nowadays with heart diseases most of peoples are dying lock process to find problem agile fashion in remote areas. In this research help to peoples who are staying remote also to find problem in heart on which location and how much problem to near and finally gives best analysis methodology for automated analysis for MultiSlice CT Angiogram images. Multi slice CT scanner is used to identify heart disease. Multi-detector CT is considered convenient and reliable non-invasive imaging modality for assessment of human angiogram 3D images. Automatic hart segmentation from Computed Tomography (CT) is highly demanded. Accurate hart segmentation is a crucial for computer-aided heart disease diagnosis and treatment planning. After segmentation and future extraction then identify whether the patient angiogram waveform has disease or not. For that, Support Vector Machine method is used to confirm the presence of disease. Neural Networks can solve different types of nonlinear problems in image classification and retrieval process. After that majorly focus on research learning methodologies for improve performance of the Multi Slice CT Angiogram images. So, in this research is summarizing the problem with liner of RBF neural network, Non-Liner SVM and RBF NN with liner and non-liner. Final, RBF NN with liner and non-liner provided more value and proved as best compare with other existing methodologies. This methodology consumes less time for both learning as well as testing comparatively than any other methods like back propagation. This issue drastically improves the estimation efficiency and accuracy for real time 128, 256 slices CT scan angiogram images.
Similar to Ultrasound image presentation Tim Hartshorne (20)
Towards diagnosis of rotator cuff tears in 3-D MRI using 3-D convolutional ne...
Towards diagnosis of rotator cuff tears in 3-D MRI using 3-D convolutional ne...
Individually Optimized Contrast-Enhanced 4D-CT for Radiotherapy Simulation in...
Individually Optimized Contrast-Enhanced 4D-CT for Radiotherapy Simulation in...
Assessment of Femoral Tunnel Placement in ACL Reconstruction
Assessment of Femoral Tunnel Placement in ACL Reconstruction
Fundación EPIC _ "TAC para planificar el procedimiento e impresión 3D: es rea...
Fundación EPIC _ "TAC para planificar el procedimiento e impresión 3D: es rea...
Survival report of 76 breast cancer patients under three different treatments
Survival report of 76 breast cancer patients under three different treatments
Radiomics and Deep Learning for Lung Cancer Screening
Radiomics and Deep Learning for Lung Cancer Screening
Digital Image Processing Assessment in Multi Slice CT Angiogram using Liner, ...
Digital Image Processing Assessment in Multi Slice CT Angiogram using Liner, ...
More from PHEScreening
NHS screening leaflet short urls and qr codes PDF
This document provides short URLs and QR codes for digital information leaflets about various NHS screening programs in the UK, including antenatal and newborn, AAA, bowel cancer, breast cancer, cervical cancer, and diabetic eye screening. Short URLs and QR codes are included to easily direct people to online collections of digital information leaflets for each screening program through mobile devices.
NHS screening leaflet short urls and qr codes
This document provides short URLs and QR codes for digital information leaflets about various NHS screening programs in the UK, including antenatal and newborn, AAA, bowel cancer, breast cancer, cervical cancer, and diabetic eye screening. Short URLs and QR codes are included to easily direct people to online collections of digital information leaflets for each screening program through mobile devices.
PHE screening inequalities conference final slides
This document outlines plans for a conference on addressing inequalities in screening. The aims of the conference are to share information on actions being taken to tackle inequalities, seek expert input on further steps, and discuss successes and new learning. The document provides background on PHE's screening inequalities strategy, examples of data showing inequalities, and initiatives underway like the FIT screening implementation and health equity audit toolkit. Speakers will discuss evidence-based practices to address inequalities including effective invitee interventions and potential program-level changes. The final section covers accessing screening data to support inequalities work while complying with information governance.
AAA screening nurses inequalities presentation final
1) The document discusses health inequalities and screening inequalities, noting that uptake rates tend to be lower for those in more deprived socioeconomic groups and for certain minority populations.
2) It provides an overview of the Public Health England's Screening Division Inequalities Strategy, which aims to increase uptake in the most deprived areas by 10% by addressing barriers to screening.
3) The strategy involves tools to help services analyze uptake data and identify groups with lower participation, as well as guidance on improving access for populations such as those with severe mental illness.
AAA screening technicians inequalities presentation final
The document discusses health inequalities in cancer screening programs. It aims to familiarize screening technicians with health inequalities, update them on initiatives to address inequalities from the UK Public Health England screening division, and explore further actions that could be taken. It notes that screening inequalities exist for groups experiencing economic deprivation, minority ethnic groups, people with disabilities, and other protected groups. Addressing inequalities requires understanding differences in participation within and between screening programs and targeting groups at higher risk who are less likely to participate. Actions discussed include analyzing screening data to identify inequalities, making programs more accessible, and establishing collaboration groups to share information.
AAA Technicians - Screening Inequalities
1) The document discusses health inequalities in cancer screening programs. It notes that uptake rates tend to be lower for populations experiencing economic deprivation, belonging to minority ethnic groups, or having disabilities.
2) Data is presented showing gaps in life expectancy between deprived and affluent areas of up to 9 years for males. Screening coverage and outcomes also tend to be lower for disadvantaged groups.
3) Actions are proposed to improve accessibility of screening for people with disabilities or severe mental illness through targeted outreach and accommodations. Establishing collaborations through online platforms and sharing work at program board meetings is encouraged.
AAA Nurses - Screening Inequalities
This document discusses health inequalities and screening inequalities. It aims to refresh knowledge on health inequalities, update on the Public Health England screening division's inequalities strategy, and explore actions screening nurses can take to tackle inequalities. It provides data showing screening uptake disparities based on factors like learning disabilities, ethnicity, and socioeconomic status. It also outlines guidance and tools to help screening services increase uptake in deprived areas and make screening more accessible for groups facing inequalities.
AAA Screening : Extending the screener role
This document describes extending the role of screening technicians in an abdominal aortic aneurysm (AAA) screening program to include basic physical health checks. It provides details on the current and proposed screening models, including the additional training and guidance technicians receive to take blood pressure and seek nurse advice. An example is given of how a high blood pressure reading was identified during screening and subsequently treated, benefiting both the patient and their GP. Feedback from patients and GPs is positive about the expanded technician role in detecting other health issues alongside AAA screening.
AAA Screening : Extending the screener role for nurses
The document discusses extending the role of screening technicians in an abdominal aortic aneurysm (AAA) screening program to include basic physical health checks. The program saw a decline in eligible men for screening over time as the population grew. The extended screener role would have technicians take basic observations like blood pressure and seek nurse practitioner advice if needed. Patients would receive education materials and follow up calls. Nurses would conduct further assessments over the phone. The changes aim to catch other health issues and assure quality through training, audits, and patient and doctor feedback. The feedback received has been positive.
AAA screening national programme update September 2019: Lisa Summers
This document provides a national update on the AAA screening programme in the UK. It discusses updates to clinical leads, screening figures, key performance indicators, standards and guidance, IT systems, equipment evaluation, rationale for modifying surveillance intervals, and initiatives across the four nations and to address inequalities in screening.
Improving outcomes of patients on AAA surveillance Adam Haque
This document discusses improving outcomes for patients undergoing abdominal aortic aneurysm (AAA) surveillance through exercise interventions. It presents evidence that cardiovascular fitness, as measured by cardiopulmonary exercise testing (CPET), is a key determinant of outcomes for AAA patients. A trial is proposed to evaluate the effects of a 24-week patient-directed exercise program on CPET measures of fitness for AAA surveillance patients compared to standard advice. The goal is to determine if objective measures of cardiovascular fitness can be improved through a scalable and deliverable exercise program to provide benefits like reduced peri-operative risk and improved survival for AAA patients.
AAA nurses training: programme boards presentation September 2019
This document discusses programme boards for screening quality assurance. It notes that nurses rarely attend all programme boards due to small team sizes and priority being given to patient assessments. Programme boards ensure screening programmes meet national standards and involve multiple stakeholder organizations. They discuss performance against quality standards, learning from incidents, and service improvement initiatives. The most discussed topics include performance metrics, incidents and lessons learned, quality assurance visit outcomes, and risks/mitigation plans. Nursing contributions could involve audits on access, uptake, and waiting times. Key messages from boards should be communicated to nursing teams.
AAA screeners LGBT awareness training September 2019
The document discusses LGBTQ+ awareness in abdominal aortic aneurysm screening programs, including definitions of key terms like sexual orientation, gender identity, and pronouns. It also notes potential health inequalities faced by LGBTQ+ people and how current AAA screening procedures and invitations may need improvements to be more inclusive of transgender and non-binary individuals.
Digital screening information event 2 October 2019
Slides from the event for antenatal screening co-ordinators in Birmingham on 2 October 2019 to discuss the plans for moving to digital screening information.
NHS Breast Screening Programme & Association of Breast Surgery Audit
The document describes the NHS Breast Screening Programme (NHSBSP) and Association of Breast Surgery (ABS) audit. The audit compares surgical data to quality assurance standards to assess performance. It analyzes data on all breast cancers detected through screening in the UK each year. The annual audit has three parts - the main audit examines the most recent year's data, the adjuvant audit examines treatment data from the prior year, and the survival audit examines 5-year survival rates. The document provides guidance on extracting data from the NBSS database system, checking the data for errors or missing information, and resolving issues by updating records in NBSS before uploading the data to the Breast Screening System Information System (BSIS
IDPS programme update Sharon Webb
This document provides an update on the Infectious Diseases in Pregnancy Screening (IDPS) Programme in the UK. It discusses the aims of the programme, which include enabling early detection and treatment of infections in pregnancy to reduce mother-to-child transmission. It summarizes screening activity data which shows high uptake rates of over 99% for HIV, hepatitis B, and syphilis screening. It also discusses efforts to improve laboratory quality, establish screening standards and outcomes data, and provide education resources to professionals and the public. Specific updates are provided on actions relating to HIV, syphilis, hepatitis B, and developing seamless maternal and neonatal pathways between screening and immunization programs.
10. Siobhan O'callaghan findings from QA activities
The QA advisor summarizes findings from 30 QA visits reports between September 2017 and July 2018. A total of 786 QA recommendations were made across various themes. The top theme was infectious diseases in pregnancy, receiving 218 recommendations. Of these, 61 recommendations were specific to the laboratory, focusing on issues like properly identifying and tracking antenatal samples, notifying screening results, and ensuring UKAS accreditation. Generic recommendations that appeared across themes included formalizing governance, managing incidents, and meeting standards for staff training and turnaround times.
9. Judith Timms HIV screening incidents
This document discusses false positive HIV results that can occur during HIV screening. The main causes of false positives are wrong blood in the tube or laboratory error. Laboratory error is found to be the most common cause, responsible for false positives in 8 of 9 cases reviewed from 2014 to 2017. Specific cases of laboratory errors are presented, including possible contamination during automated testing processes and issues with old laboratory equipment. The implications of false positive results, such as distress to patients, are also covered.
8. Nadia Permalloo learning from incidents
This document summarizes themes from quarterly incident reports of a screening program covering October 2015 to December 2017. Key issues identified include screening without informed consent, insufficient samples not being repeated in a timely manner, tracking and communication failures leading to unreported positive screening results, delays when using reference laboratories, and unconfirmed screening results being communicated to patients. The document concludes with a checklist of questions around improving processes to address these issues.
7. Tom Lewis Getting it right for pathology presentation
This document summarizes a presentation on the Getting It Right First Time (GIRFT) program and its workstream focused on pathology. GIRFT aims to reduce unwarranted variation in clinical care through data collection, identifying best practices, and promoting changes. The pathology workstream is led by four clinical leads and aims to measure current variability in pathology services, create a vision for the future, and test changes. Key activities will include collecting data through questionnaires and site visits to understand variations and identify opportunities for improvement.
More from PHEScreening (20)
PHE screening inequalities conference final slides
PHE screening inequalities conference final slides
AAA screening nurses inequalities presentation final
AAA screening nurses inequalities presentation final
AAA screening technicians inequalities presentation final
AAA screening technicians inequalities presentation final
AAA Screening : Extending the screener role for nurses
AAA Screening : Extending the screener role for nurses
AAA screening national programme update September 2019: Lisa Summers
AAA screening national programme update September 2019: Lisa Summers
Improving outcomes of patients on AAA surveillance Adam Haque
Improving outcomes of patients on AAA surveillance Adam Haque
AAA nurses training: programme boards presentation September 2019
AAA nurses training: programme boards presentation September 2019
AAA screeners LGBT awareness training September 2019
AAA screeners LGBT awareness training September 2019
Digital screening information event 2 October 2019
Digital screening information event 2 October 2019
NHS Breast Screening Programme & Association of Breast Surgery Audit
NHS Breast Screening Programme & Association of Breast Surgery Audit
10. Siobhan O'callaghan findings from QA activities
10. Siobhan O'callaghan findings from QA activities
7. Tom Lewis Getting it right for pathology presentation
7. Tom Lewis Getting it right for pathology presentation
Recently uploaded
vonoprazan A novel drug for GERD presentation
Vonoprazan, a new potassium acid channel blocker used in the conditions of GERD and gastric ulcer, duodenal ulcer ....
Adhd Medication Shortage Uk - trinexpharmacy.com
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
Ketone bodies and metabolism-biochemistry
This slide consists of all the topics of ketone . This can be used for exam purpose for writing about Diabetic keto acidosis etc . Thank you
10 Benefits an EPCR Software should Bring to EMS Organizations
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
NARCOTICS- POLICY AND PROCEDURES FOR ITS USE
This document outlines policies and procedures for handling narcotic and controlled drugs in NABH accredited hospitals.
Histololgy of Female Reproductive System.pptx
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Acute Gout Care & Urate Lowering Therapy .pdf
In this document , the management of acute gout attacks and a description of urate lowering therapy is mentioned.
CLEAR ALIGNER THERAPY IN ORTHODONTICS .pptx
Dr. ZANAB FARHEEN FAYAZ ,MDS(ORTHODONTICS & DENTOFACIAL ORTHOPEDICS ).
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.Travel Clinic Cardiff: Health Advice for International Travelers
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
une 2024 Oncology Cartoons By Dr Kanhu Charan Patro
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Do you have abnormal smell after periods? It may be vaginitis. Do not worry, herbal medicine Fuyan Pill can help you get a cure.
Recently uploaded (20)
Muscles of Mastication by Dr. Rabia Inam Gandapore.pptx
Muscles of Mastication by Dr. Rabia Inam Gandapore.pptx
10 Benefits an EPCR Software should Bring to EMS Organizations
10 Benefits an EPCR Software should Bring to EMS Organizations
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Outbreak management including quarantine, isolation, contact.pptx
Outbreak management including quarantine, isolation, contact.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
Travel Clinic Cardiff: Health Advice for International Travelers
Travel Clinic Cardiff: Health Advice for International Travelers
Cell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune Disease
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Ultrasound image presentation Tim Hartshorne
- 1. AAA CST Information & Support Day London 27th April 2018 1: Tim Hartshorne 2: Colin Nice 3: Questions, comments and feedback
- 3. Equipment. 1
- 4. ‘Paper clip’ test Quick and easy to assess element damage Equipment. 2
- 5. It’s a representation of the reflection and scattering of ultrasound waves caused by variation in acoustic impedance (dependent on speed of sound and density) of an aneurysm. What is this?
- 6. Variation in image quality
- 7. Should this pass image QA?
- 8. Transverse image Longitudinal image (4 images ‘stitching’ together the length of the abdominal aorta) Should this pass image QA?
- 9. Being objective? As CST’s do we all agree what constitutes an acceptable ultrasound image and accurate measurement of aortic diameter? As CST’s do we all provide the same level of feedback regarding image quality and image QA?
- 10. We can’t be absolutely certain Subjectively, we probably do but can we improve guidance and provide a clearer definition/description of what is an acceptable image? Before handing over to Colin Nice there are two other brief points to share
- 11. Is there another way of undertaking image QA?
- 12. Why not automate the process?
- 13. ScanNav® automated peer review • ScanNav® is used during the FASP Fetal Anomaly Scan at 18+0 to 20+6 weeks • ScanNav® gives real time feedback on whether paused images are fit for purpose and whether the protocol has been followed. Prototype in use in John Radcliffe Hospital Oxford since June 2015
- 14. Images of the aorta or often much more variable in quality than those obtained during FAS due to bowel gas and depth (particularly high BMI) The system also appears to analyse frozen images rather than live images The system would need to be ‘trained’ with input from sonographers on thousands of aortic images There are structures in the abdomen such as the IVC that can mimic the aorta How would the screeners work with the system in screening clinics and would it add significantly to the length of the examination? Would the system be able to assess the accuracy of calliper placement and also confirm that the widest diameter of the aorta has been measured? Automated peer review not currently appropriate for AAA
- 15. Other ways of looking at performance
- 16. 0 1 2 3 4 5 012345 L T 0 1 2 3 4 5 6 7 -0.6 -0.4 -0.2 0.0 0.2 0.4 0.6 1011 (L+T)/2 T-L n =988 (94%) n =60 (6%) Scatter plot Bland Altman Plot Longitudinal diam Using data? Slide kindly provided by Dave Wright
- 17. 0 1 2 3 4 5 6 7 -0.6 -0.4 -0.2 0.0 0.2 0.4 0.6 1945 (L+T)/2 T-L n =202 (88%) spread = 0.0779 n =28 (12%) Slide kindly provided by Dave Wright Very few 2.5 to 2.9cm aortas?
- 18. 0 1 2 3 4 5 6 7 -0.6 -0.4 -0.2 0.0 0.2 0.4 0.6 1011 (L+T)/2 T-L n =988 (94%) n =60 (6%) Slide kindly provided by Dave Wright Diameter between 2.5-2.9cm
- 19. 0 1 2 3 4 5 6 7 -0.6 -0.4 -0.2 0.0 0.2 0.4 0.6 9036 (L+T)/2 T-L n =1853 (98%) n =34 (2%) Slide kindly provided by Dave Wright Less variation between TS and LS diameter
- 20. ‘Pushing’ the boundary? Should the calliper position be penalised?