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TRANSGENIC
ORGANISMS
By: Olivia Stanton
What is a transgenic organism?
            ~ a transgenic, or genetically modified, organism
            is one that has been altered through
            recombinant DNA technology, which involves
            either the combining of DNA from different
            genomes or the insertion of foreign DNA into a
            genome




                                                GloFish
http://en.wikipedia.org/wiki/File:GloFish.jpg
How transgenic organisms
work…
Three Main Methods…
   DNA Microinjection
       A foreign gene is directly injected into a fertilized egg that is put into a
        female animal that acts as a surrogate mother for the egg.
   Retrovirus-Mediated Gene Transfer
       A retrovirus is a virus that attaches to an organism’s DNA and changes it
        to include a new characteristic. Scientists expose ordinary cells to a
        retrovirus when they are trying to create transgenic animals.
   Embryonic Stem Cell-Mediated Gene Transfer
       Stem cells are blank cells that can turn into any type of cell. Scientists
        modify these cells, and then add them to an embryo, which is a fertilized
        egg that develops and grows until it hatches or is born.
ADVANTAGES                               DISADVANTAGES
   Agriculture
       Breeding
           Quickly produce animals with desired
            traits
       Quality
           Cows that produce more milk, pigs and
            cattle that have more meat, sheep that
            grow more wool, etc.
       Disease Resistant
   Medicine
       Xenotransplantation
           Animals produce organs that can be
            used in transplants
       Nutritional Supplements
       Pharmaceuticals
       Human Gene Therapy
   Industry
       Production of useful materials
           Ex] Spider Goat ~ makes silk
Spider Goat
The spider goat produces large amounts of silk, with this silk industries
are able to create light, tough, flexible material that can be used in such
applications as military uniforms, medical microstructures, and tennis
racket strings.

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Transgenic organismspp

  • 2. What is a transgenic organism? ~ a transgenic, or genetically modified, organism is one that has been altered through recombinant DNA technology, which involves either the combining of DNA from different genomes or the insertion of foreign DNA into a genome GloFish http://en.wikipedia.org/wiki/File:GloFish.jpg
  • 3. How transgenic organisms work… Three Main Methods…  DNA Microinjection  A foreign gene is directly injected into a fertilized egg that is put into a female animal that acts as a surrogate mother for the egg.  Retrovirus-Mediated Gene Transfer  A retrovirus is a virus that attaches to an organism’s DNA and changes it to include a new characteristic. Scientists expose ordinary cells to a retrovirus when they are trying to create transgenic animals.  Embryonic Stem Cell-Mediated Gene Transfer  Stem cells are blank cells that can turn into any type of cell. Scientists modify these cells, and then add them to an embryo, which is a fertilized egg that develops and grows until it hatches or is born.
  • 4. ADVANTAGES DISADVANTAGES  Agriculture  Breeding  Quickly produce animals with desired traits  Quality  Cows that produce more milk, pigs and cattle that have more meat, sheep that grow more wool, etc.  Disease Resistant  Medicine  Xenotransplantation  Animals produce organs that can be used in transplants  Nutritional Supplements  Pharmaceuticals  Human Gene Therapy  Industry  Production of useful materials  Ex] Spider Goat ~ makes silk
  • 5. Spider Goat The spider goat produces large amounts of silk, with this silk industries are able to create light, tough, flexible material that can be used in such applications as military uniforms, medical microstructures, and tennis racket strings.