The document describes a thesis submitted for a Doctor of Philosophy degree that investigated optical time-division multiplexing (OTDM) techniques for high-speed local and wide area network interconnects. Specifically, it demonstrated a 40 Gbit/s optical TDMA network establishing 2.5 Gbit/s connections between computer workstations using single-mode fiber. The thesis explored different optical pulse sources for OTDM including gain-switched distributed feedback lasers and electroabsorption modulators. It also investigated techniques for pulse compression, modulation, multiplexing, and demultiplexing to enable fast reconfigurable high-bandwidth interconnects.