Interferential Current or therapy for Physiotherapy studentsSaurab Sharma
This lecture intends to provide general outline about the uses, parameters, precautions and contraindications of interferential current for undergraduate physiotherapy students at Kathmandu University School of Medical Sciences, Nepal. After the lecture, students will explore the evidences about current practices on the uses of IFT in various musculoskeletal pain conditions, critically appraise them and present the evidences to the class.
Interferential Current or therapy for Physiotherapy studentsSaurab Sharma
This lecture intends to provide general outline about the uses, parameters, precautions and contraindications of interferential current for undergraduate physiotherapy students at Kathmandu University School of Medical Sciences, Nepal. After the lecture, students will explore the evidences about current practices on the uses of IFT in various musculoskeletal pain conditions, critically appraise them and present the evidences to the class.
Theralase Technologies Inc., founded in 1995, designs, develops, manufactures and markets patented, superpulsed laser technology utilized in biostimulation and biodestruction applications. Theralase technology is safe and effective in treating pain, inflammation and for tissue regeneration of neural muscular skeletal conditions and wound healing. As well, these applications extend to the care of animals by veterinarians. Theralase complies with FDA, Health Canada, CE, ISO-13485 and CSA-601 regulatory approvals to ensure efficacy, safety and quality in manufacture. Theralase is currently developing patented Photo Dynamic Compounds (PDCs) that are able to target and destroy cancers, bacteria and viruses when light activated by Theralase’s proprietary and patented laser technology.
LASER SURGERY
Class 4 > 500 mW Surgical lasers
Introduction
Surgery using a laser to cut tissue instead of a scalpel
Laser scalpel
Highly focused laser beam efficiently ablates (either vaporize or chip away) the living tissue.
At the same time, it seals (welds) capillaries, small blood vessels, lymphatics, and nerve endings, with significant benefits to both patients and surgeons.
MECHANISM OF ACTION
Photovaporolysis
Char – remnant of non-fluid cellular component.
Photoplasmolysis
Crater
Zone of carbonization- the limit of vaporization
Zone of coagulation and thermal necrosis- Slightly farther away from the center. This zone will eventually die.
Zone of hyperthermia- Farthest from the center. Beyond these zones there is no effect Depth of the crater and the diameter of these zones are directly related to power density.
20-watt Carbon Dioxide laser with plume evacuator
Highly absorbed by water, making it perfect for tissue cutting, vaporization and acoustical destruction.
Thermal injury to surrounding tissue is very superficial.
Lateral thermal injury of 0.05 mm to 0.1 mm
Because there is such minimal lateral thermal damage, injury to surrounding tissues is limited to what you see during application of the laser energy.
General parameters for CO2 laser use
Routine incision: Spot Diameter: 0.4 mm
Power Setting: 6 to 10 W
Routine ablation/vaporization Spot Diameter: 0.8 mm
Power Setting: 10 to 20 W
Delicate location incision: Spot Diameter: 0.3 to 0.4 mm
Power Setting: 3 to 6 W
Routine excision: Spot Diameter: 0.8 mm
Power Setting: 8 to 15 W
LASER USES
Less Pain - The laser seals nerve endings as it cuts. So the patient will have less pain.
Less Bleeding - The laser seals small blood vessels during surgery and speeds up surgery by minimizing bleeding.
Less Swelling - No physical contact except the invisible laser beam. The tissue will not be crushed.
Sterilization - The laser sterilizes the surgical site as it cuts. Bacteria and viruses are vaporized by the laser during laser surgery.
Faster Recovery - Less bleeding and swelling will result in faster healing.
Precision - The beam direction and power can be controlled precisely to remove thin layers of tissue and produce minimal side effects on the surrounding healthy tissue.
Reduced hospitalization time - All above factor will greatly reduce the procedure time.
Laser surgery benefits for surgeons
Unique surgical capabilities: Laser surgery improves many surgical procedures by making them simpler and reducing risk. This enables surgeries that are not practical with conventional methods.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Educational seminar presenting the facts of High Power Laser Medicine and how it is used to stop pain—without surgery and without drugs. Property of AvicennaLaser.com.
1. Production, marketing and distribution of the TLC-1000 and TLC-2000 Theralase Superpulsed Laser Technology for sale to healthcare practitioners nationally and internationally, interested in the safe and effective treatment of neuromuscular skeletal conditions through the elimination of pain and inflammation and the accelerated regeneration of tissue.
2. Commercialization of the patented TLC-3000 Laser and Photo Dynamic Compound Technology platform through preclinical research, FDA clinical trials and new technology development in the direct destruction of cancers for oncological applications and in the destruction of bacteria for sterilization of medical and food processing facilities.
Theralase Technologies Inc., founded in 1995, designs, develops, manufactures and markets patented, superpulsed laser technology utilized in biostimulation and biodestruction applications. Theralase technology is safe and effective in treating pain, inflammation and for tissue regeneration of neural muscular skeletal conditions and wound healing. As well, these applications extend to the care of animals by veterinarians. Theralase complies with FDA, Health Canada, CE, ISO-13485 and CSA-601 regulatory approvals to ensure efficacy, safety and quality in manufacture. Theralase is currently developing patented Photo Dynamic Compounds (PDCs) that are able to target and destroy cancers, bacteria and viruses when light activated by Theralase’s proprietary and patented laser technology.
LASER SURGERY
Class 4 > 500 mW Surgical lasers
Introduction
Surgery using a laser to cut tissue instead of a scalpel
Laser scalpel
Highly focused laser beam efficiently ablates (either vaporize or chip away) the living tissue.
At the same time, it seals (welds) capillaries, small blood vessels, lymphatics, and nerve endings, with significant benefits to both patients and surgeons.
MECHANISM OF ACTION
Photovaporolysis
Char – remnant of non-fluid cellular component.
Photoplasmolysis
Crater
Zone of carbonization- the limit of vaporization
Zone of coagulation and thermal necrosis- Slightly farther away from the center. This zone will eventually die.
Zone of hyperthermia- Farthest from the center. Beyond these zones there is no effect Depth of the crater and the diameter of these zones are directly related to power density.
20-watt Carbon Dioxide laser with plume evacuator
Highly absorbed by water, making it perfect for tissue cutting, vaporization and acoustical destruction.
Thermal injury to surrounding tissue is very superficial.
Lateral thermal injury of 0.05 mm to 0.1 mm
Because there is such minimal lateral thermal damage, injury to surrounding tissues is limited to what you see during application of the laser energy.
General parameters for CO2 laser use
Routine incision: Spot Diameter: 0.4 mm
Power Setting: 6 to 10 W
Routine ablation/vaporization Spot Diameter: 0.8 mm
Power Setting: 10 to 20 W
Delicate location incision: Spot Diameter: 0.3 to 0.4 mm
Power Setting: 3 to 6 W
Routine excision: Spot Diameter: 0.8 mm
Power Setting: 8 to 15 W
LASER USES
Less Pain - The laser seals nerve endings as it cuts. So the patient will have less pain.
Less Bleeding - The laser seals small blood vessels during surgery and speeds up surgery by minimizing bleeding.
Less Swelling - No physical contact except the invisible laser beam. The tissue will not be crushed.
Sterilization - The laser sterilizes the surgical site as it cuts. Bacteria and viruses are vaporized by the laser during laser surgery.
Faster Recovery - Less bleeding and swelling will result in faster healing.
Precision - The beam direction and power can be controlled precisely to remove thin layers of tissue and produce minimal side effects on the surrounding healthy tissue.
Reduced hospitalization time - All above factor will greatly reduce the procedure time.
Laser surgery benefits for surgeons
Unique surgical capabilities: Laser surgery improves many surgical procedures by making them simpler and reducing risk. This enables surgeries that are not practical with conventional methods.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Educational seminar presenting the facts of High Power Laser Medicine and how it is used to stop pain—without surgery and without drugs. Property of AvicennaLaser.com.
1. Production, marketing and distribution of the TLC-1000 and TLC-2000 Theralase Superpulsed Laser Technology for sale to healthcare practitioners nationally and internationally, interested in the safe and effective treatment of neuromuscular skeletal conditions through the elimination of pain and inflammation and the accelerated regeneration of tissue.
2. Commercialization of the patented TLC-3000 Laser and Photo Dynamic Compound Technology platform through preclinical research, FDA clinical trials and new technology development in the direct destruction of cancers for oncological applications and in the destruction of bacteria for sterilization of medical and food processing facilities.
Theralase Technologies Inc. designs, manufactures and markets patented, superpulsed laser technology used in healing injured tissue and destroying cancer. Theralase technology is safe and effective in eliminating pain, reducing inflammation and accelerating tissue regeneration of numerous nerve, muscle and joint injuries in both humans and animals. Theralase complies with all FDA, Health Canada, CE and international regulatory approvals to ensure effective, safe and high quality products. Theralase is actively developing patented Photo Dynamic Compound (PDC) technology that is able to target and destroy cancers, bacteria and viruses when light activated by Theralase's proprietary and patented laser technologies.
Low Level Laser Therapy (LLLT) is a fast growing field of medicine recognized by every major industrialized nation in the world, offering painless, non-invasive and highly effective drug-free solutions. Able to treat a plethora of neural muscular skeletal conditions, LLLT is often the only solution that is available to the highly trained practitioner to control disease when conventional therapies have come up lacking.
Theralase Technologies Inc., founded in 1995, designs, develops, manufactures and markets patented, superpulsed laser technology utilized in biostimulation and biodestruction applications. Theralase technology is safe and effective in treating pain, inflammation and for tissue regeneration of neuro musculoskeletal conditions and wound healing. Theralase is currently developing proprietary Photo Dynamic Compounds (PDCs) that are able to target and destroy cancers, bacteria and viruses when light activated by Theralase’s proprietary and patented laser technology.
Theralase Technologies Inc., founded in 1995, designs, develops, manufactures and markets patented, superpulsed laser technology utilized in biostimulation and biodestruction applications. Theralase technology is safe and effective in treating pain, inflammation and for tissue regeneration of neural muscular skeletal conditions and wound healing. As well, these applications extend to the care of animals by veterinarians. Theralase is currently developing patented Photo Dynamic Compounds (PDCs) that are able to target and destroy cancers, bacteria and viruses when light activated by Theralase’s proprietary laser technology.
Theralase Technologies Inc., founded in 1995, designs, develops, manufactures and markets patented, superpulsed laser technology utilized in biostimulation and biodestruction applications. Theralase technology is safe and effective in treating pain, inflammation and for tissue regeneration of neural muscular skeletal conditions and wound healing. Theralase is currently developing patented Photo Dynamic Compounds (PDCs) that are able to target and destroy cancers, bacteria and viruses when light activated by Theralase’s proprietary and patented laser technology.
Theralase is currently developing patented Photo Dynamic Compounds (PDCs) that are able to target and destroy cancers, bacteria and viruses when light activated by Theralase’s proprietary and patented laser technology.
Theralase's Photo Dynamic Therapy (PDT) Division, announced today study results proving that its patented Photo Dynamic Compounds (PDCs) were significantly more effective in destroying a human urinary bladder carcinoma cell line than a FDA approved photosensitizer, aminolevulinic acid (ALA).
Theralase Technologies Inc. (TSX-V: TLT) announced today the successful results of preclinical studies (in-vitro and in-vivo) demonstrating significant destruction of various brain and colon cancer cell lines. The new proprietary Theralase treatment sharply delayed the tumour progression, when attacked by the Theralase patented light activated Photo Dynamic Compounds (PDCs), signifying a new and broadly promising approach to cancer treatment. When treated with the Theralase PDCs, cancerous mice survived cancer-free for more than 100 days post-treatment, a highly significant milestone.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
1. Healing at the Speed of Light
COLD LASER THERAPY
Cold Laser Healing
2. Pg.2
THERALASE
Founded in 1994, Theralase
builds the finest therapeutic
medical laser On the market
Theralase designs, develops and
manufactures patented, super-pulsed
laser technology utilized in biostimulation
and bio-destruction applications. The
technology is safe and effective in the
treatment of chronic pain, neural muscular
skeletal conditions, and wound care for
human, equine, and companion animals.
Founded in 1994, Theralase is committed
to cutting edge quantitative research to
remain the most clinically and technically
researched therapeutic medical laser in
the market.
The highly trained Theralase team
continuously strives to bring our valued
customers the latest technology,
superior customer support (technical
and marketing) and training, in order to
contribute to the success of their practice.
Used by thousands of medical practitioners worldwide
and improving the lives of human patients for over
17 years the award winning Theralase TLC-1000
laser technology is now being offered to DVMs as a
modern way to treat Equine and Companion animals
without the risk of injury or discomfort.
3. Pg.3
NEURO/MUSCULO/SKELETAL
MANAGING PAIN AND INFLAMMATION
Neuro-musculoskeletal conditions are common in people. We’ve all had aches and pains, muscle stiffness and
soreness and sprains that just won’t go away. We can even cause repetitive stress injury at work or from things
in our lives we do everyday. Pain and inflammation are things we’ve grown to accept as something we probably
will just have to endure, until now. Practitioners across North America have discovered a modern treatment
tool that heals injuries on a cellular level using the Theralase line of therapeutic laser products.
The Theralase superpulsed laser system can deeply penetrate through skin to promote cellular regeneration
at the source of the injury. Laser light energy helps to repair damaged cells by accelerating the body’s natural
healing mechanisms. Depending on the severity of the injury or condition your patient can return to an active
lifestyle or just be pain free within a few weeks versus a few months of rest.
4. Pg.4
THE SCIENCE BEHIND THE PRODUCT
Super pulsed 905nm
technology Able to
penetrate 4” into tissue
Safe and Effective
Theralase’s Superpulsed 905 nm near infrared and 660nm visible red laser technology accelerates healing by
reducing pain and inflammation while staying below the Maximal Permissible Exposure (MPE) tolerance for
human and animal cells.
100MW 5MW 100MW
SUPER PULSED CONTINUOUS CONTINUOUS
(INSTANTANEOUS) WAVE WAVE
50,000 5 mW 100
mW / Cm² Cm² mW/Cm²
TISSUE SURFACE
1/4” Penetration Depth 18,450 mW / Cm² 1.8 mW / Cm² 37 mW / Cm²
1” Penetration Depth 6,810 mW / Cm² 0.7 mW / Cm² 14 mW / Cm²
4” Penetration Depth 2,510 mW / Cm² 0.3 mW / Cm² 5 mW / Cm²
True Laser Diodes vs. LED
Theralase utilizes True laser diodes in its probes which focus 100% of the light where you are applying the
laser. The light points where it is directed much like a flashlight beam in the dark. LED light projects light in
all directions with only 5-6% directed in a forward manner. Think of an old fashioned light bulb that lights
up a room but isn’t focused. Theralase’s collimated lasers directs all of their light where you need it, at the
application site.
Laser 100% of light energy in the forward direction
100 mW LASER 100 mW
LED - 5 to 6 % of light energy in the forward direction
15 mw 0.9 mW
5. Pg.5
THE SCIENCE BEHIND THE PRODUCT
the only laser that activates all
three known cellular pathways
660 nm - Accelerated Healing (Adenosine Triphosphate
(ATP) Pathway
Cells that lack energy are unable to participate in the healing process. Light
energy is delivered to injured cells which in turn absorbs the light and converts
it into food energy and uses it to replenish themselves. Once cells are fully
recharged they are able to replicate and divide and build upon one another
to heal the injured area. Theralase stimulates the mitochondria of the cell
to produce more ATP (energy) to be used to repair damaged tissue through
Oxidative Phosphorylization.
905 nm - Inflammation (Nitric Oxide (NO) Pathway)
When tissue injury occurs, the inflammatory process is initiated to immobilize
the area and prevent further damage, which acts as a signal that the body is
hurt. This process is usually associated with pain caused by pressuring nerve
endings. In order to reabsorb this interstitial fluid and decrease inflammation
in the region the body produces Nitric Oxide (NO) which has been proven
to relax the limphatic system and increase the diameter of capillaries, This
process not only reduces inflammation but brings much needed oxygen and
other metabolites to the injured tissue aiding in their natural healing.
Independent research shows that the proprietary Theralase 905nm super-
pulsed technology increases the production of NO by 700% (Published in
Lasers in Surgery and Medicine 03/2009).
905 nm - Pain (Lipid Absorption Pathway)
Pain results when a stimulus causes action potentials to rapidly propogate
along a nerve cell. These actions potentials are primarily due to an expulsion
of positively charged sodium ions (Na+) and an influx of potassium (K+) ions
into the nerve cell altering the electrical potential across the membrane. The
peak absorption of lipids occurs in the 905 nm to 910 nm range Laser light
is thus directly absorbed by receptors within the bi-lipid cellular membrane
of nerve cells. Once absorbed, the laser light will increase the porosity of the
cellular membrane allowing for reabsorption of sodium ions and an expulsion of
potassium ions across the membrane rebalancing the sodium-potassium pump
and removing the pain signal.
Photons with wavelengths of 905nm effectively removes the pain signal at the
source by rebalancing the sodium potassium pathway.
7. Pg.7
TREATMENT
Efficacy rates of up to 90%
with no side effects
1. Decrease / eliminate pain
2. Reduce inflammation
3. Promote new blood vessels and tissue growth
4. Promote nerve axon growth
5. Faster wound healing and closure
6. Non-Invasive / No Side Effects
7. Extremely Safe / Drug Free
8. Highly Effective for Patient (90% efficacy rates)
9. Alternative to other treatments; such as Analgesics, NSAID’s,
Cox-2 Inhibitors, TENS, Ultrasound, Inferential
Acute Sub-acute CHRONIC
CONDITIONS CONDITIONS CONDITIONS
5 Treatment sessions 10 Treatment sessions 20 Treatment sessions
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BUT DON’T TAKE OUR WORD FOR IT...
HERE’S WHAT YOUR COLLEAGUES
ARE SAYING ABOUT THERALASE
DR. ALBERT SCALES DC
“I first purchased a therapeutic unit 2 years ago. The laser system quickly doubled my referrals within a few
weeks. Initially I used it to complement my other treatment modalities including ultrasound and electrotherapy.
I have recently upgraded to a more powerful system and now use it as a stand alone therapy that has replaced
all other modalities. I’m averaging 200 laser treatments per month. The cost of the upgrade was offset within
3 months.”
DR. JOYCE ALLMAN, DC
“I bought a laser only 4 weeks ago. Once I finally learned how to turn it on, I have not stopped! In this short
time of owning it, it’s generating a fair bit of income for me along with a great deal of renewed enthusiasm in
myself, my staff and the patients. I’m glad I didn’t wait to purchase. This is the healing tool of the future!”
DR. STEVEN CHUI DC
“The Theralase laser has been a great addition to my practice at providing fast results through many of the
extremity injuries. I have had to use ultrasound and tens previously. This laser is amazing for both acute and
chronic injuries.”
GEORGE POULIS AND DAVE ABRAHAM
“The Theralase® Laser is the most effective technology we have ever used. Our players now rely on Theralase®
to keep them healthy and playing at their peak.”
DR. DAVID WEST DC
“I am most impressed with our clinical results using the Theralase therapeutic laser system. We have successfully
treated TMJ, rotator cuff tendonitis, carpal tunnel syndrome and discogenic conditions of the spine.”
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CLINICAL PROOF
LASER CAN BE UTILIZED TO TREAT
A NUMBER OF CONDITIONS
EFFICACY OF LOW-LEVEL LASER THERAPY IN THE MANAGEMENT OF NECK PAIN:
a SYSTEMIC REVIEW AND META-ANALYSIS OF RANDOMIZED PLACEBO OR ACTIVE
TREATMENT CONTROLLED TRIALS
Roberta T Chow, Mark I Johnson, Rodrigo A B Lopes-Martins, Jans M Bjorndal. The Lancet. 10.1016/S0140-
6736(09)61522-1. Nov 2009
We identified 16 randomized controlled clinical trials including a total of 820 patients. In acute neck pain,
results of two trials showed a relative risk (RR) of 1-69 (95% CI 1.22 - 2.33) for pain improvement of LLLT
versus placebo. Five trials of chronic pain reporting categorial data showed an RR for pain improvement of
4.05 (2.74 - 5.98) of LLLT. Patients in 11 trials reporting changes in visual analog scale had pain intensity
reduced by 19.86mm (10.04-29.68). Seven trials provided follow up data for 1-22 weeks after completion of
treatment with short term pain relief persisting in the medium term with a reduction of 22.07 mm(17.42-26.72).
Side effects from LLLT were mild and not different from those of placebo.
We show that LLLT reduces pain immediately after treatment in acute neck pain and up to 22 weeks after
completion of treatment in patients with chronic pain.
Effects of 904 Nm low-level laser therapy in the management of
lateral epicondylitis: a randomized Controlled trial
Lam LK, Cheing GL., Photomedicine and Laser Surgery. 2007 April, 25(2):65-71.
The aim of this study was to evalute the effectivenesss of 904nm low-level laser therapy (LLLT) in the
management of lateral epicondylitis. 39 patients with lateral epicondylitis were randomly assigned to be treated
with a low-level laser or placebo for 9 sessions. Mechanical pain threshold, maximum grip strength using
VAS and DASH evaluation techniques. The study revealed that LLLT in addition to exercise is effective in
improving the grip strength and subjective rating of physical function of patients with lateral epicondylitis.
efficacy of 904 nm gallium arsinide low level laser therapy in the
management of chronic myofascial pain in the neck: a double blind
and randomized controlled trial
Ali Gur, MD., Aysegul Jale Serac, Renzi Cevik, Ozlem Altindag and Serdar Sarac. Lasers in Surgery and
Medicine 2004;35(3):229-35
A prospective, double blind, randomized and controlled trial was conducted in patients with chronic myofascial
pain syndrome (MPS) in the neck to evaluate the effects of infrared low level 904nm Gallium Arsenide (Ga-
as) laser therapy (LLLT) on clinical and quality of life. 60 MPS patients were were randomly assigned to two
groups; laser treatment and placebo treatment. All patients received treatment every day except weekends foir
two weeks and were followed up at 2,3 and 12 weeks. Patients were assessed by pain at rest, pain at movement,
number of trigger points, NPAD, BDI and the Nottingham Health Profile. Results showed that the laser group
experienced a significant improvement in pain at all outcome measures (p<0.01) over the placebo group.
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SPECIFICATIONS
TLC-1000 Cold laser
BEST IN CLASS
Laser System:
Class 3 B
Laser Source:
Indium Galium Arsenide (InGaAs)
Laser Diodes
Peak Power :
50,000 mW
Wavelengths:
905 nm Near Infrared,
660 nm Visible
Delivery System:
Superpulsed
Number of Diodes: Treatment Area Size:
Multiple Probe: 9 - 5 x 905 nm, 4 x 660 nm Multiple Probe: 20 cm 2
Triple Probe: 3 - 1 x 905 nm, 2 x 660 nm Triple Probe: 1 cm 2 2
Single Probe: 1-905 nm with Collimated Beam Single Probe: 0.2 cm
Approvals:
Health Canada • FDA •CE • ISO 13485:2003
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A TURN-KEY SOLUTION
product, support and clinical
Knowledge to grow your practice
Interactive Training Resources Clinical Support
Theralase provides operation and basic use through Theralase provides ongoing clinical support through
interactive training resources available online or via “free” monthly webinars and on staff clinicians who
DVD. Simply watch the videos to see how to safely are available to discuss patient treatment plans and
and effectively update your Theralase laser. protocols.
Marketing Support
Theralase offers a number of highly efective
marketing products FREE of Charge. An online
repository of professionally developed marketing
materials is accessible 24/7 exclusively to Theralase
customers.
Extended Warranty
Should your system require maintenance or
calibration while under warranty. Theralase offers a
loaner program while your system is being serviced.
*Extended warranty options are available with every
system to ensure on-going use of this revolutionary
technology.
12. CALL TODAY FOR A FREE DEMONSTRATION
Experience the Theralase TLC 1000 Therapeutic Laser
WANT MORE INFO?
Phone 1 866 843 5273
Online www.theralase.com
E-Mail sales@theralase.com