This document provides information about laser photo therapy (LPT), including: 1) LPT uses non-thermal laser radiation to treat pain, inflammation, and accelerate wound healing in areas like joints, injuries, and wounds. 2) It has been shown to increase ATP production and stimulate collagen production, improving tissue regeneration. Over 3000 clinical publications and 160 randomized controlled studies provide scientific evidence of its effectiveness. 3) Different laser types are used depending on the intended application or treatment depth needed. LPT is considered very safe with few side effects like minor tingling and has a broad range of potential indications.

2. The Quality System
ISO 9001:2008
&
ISO 13485:2003
This is certified and checked
yearly
by the German mdc GmbH,
Stuttgart
All products are CE compliant.

3. Definition of LPT
LPT is the abbreviation for Laser Photo Therapy,
which means the treatment of symptoms like pain,
inflammation or wound healing with non-thermal
laser radiaion, LPT is used in various fields like:
Pain / inflammation: Wound healing:
- Arthrosis - Burns
- Epicondylitis - Scars / Keloids
- Carpal Tunnel Syndrom - Ulcus cruris
- Diabetic foot
Sport Injuries: Others:
- Luxation - Tinnitus
- Distortion - Acne
- Fracture - Facial Paresis
- Shoulder-Arm-Syndrom - Zoster

4. Example on tissue regeneration
After 2 weeks

5. Accelerated wound healing

6. History of LPT
In 1963 Endre Mester performed the first trreatment
of lasers on mice. He found a stimulation of hair
growth on the treated spots.*
In later studies he found also an increased
epithelization of wounds.**
* Endre Mester, B.Szende u.a.: The effect of laser beams on
the growth of hair in mice. In: Radiobiol Radiother. 9/1968,
S.621-626
** Endre Mester: Laser - induced stimulation of the
vascularisation of the healing wound. In: Separat.Exp.
30/1974, S.341-345

7. Scientific Evidence
Is there scientific evidence for LPT?
The answer is clearly: YES
- More than 3000 scientifical and clinical
publications listed in PubMed*
- More than 160 randomized placebo controlled
double blind studies**
* **: December 2011

8. Different laser types used in medicine
Different lasers for different indications:
Tatoo & hair removal – 694 nm Ruby laser (crystal)‫‏‬
Hair removal, bone cutting – 755 Alexandrite (crystal)‫‏‬
Tumor coagulation – 1064 nm NdYAG (crystal)‫‏‬
Kidney stone treatment – tunable (liquid dye laser)‫‏‬
Eye surgery – 193 nm, 248 nm, 308 nm Excimer laser (gas)‫‏‬
Dermatology – 10.600 nm CO2 laser (gas)‫‏‬
Biostimulation: LaserCat / PalmLaser / SilkLite
HeNe: 633 nm red (gas)‫‏‬
InGaAlP: 630 nm – 685 nm red (semiconductor, diode)‫‏‬
GaAlAs: 780-820-870 nm IR (semiconductor, diode)‫‏‬
GaAs: 904, 905 nm IR (semiconductor, diode)‫‏‬

9. Laser Light and Biophotons
A laser emits a special sort of light which is
monochromatic
(only one colour ==> highest power intensity)
and
• coherent
(all waves oscillate parallel to each other)‫‏‬
Biophotons of the body emit also
coherent light*
Wave peaks and wave troughs are parallel to
each other
* Prof. Dr. Fritz-Albert Popp,
Int. Institute for Biophysics, Neuss
www.biophotonen-online.de

10. The meaning of coherency
Non-coherent light
Coherent light

11. UV – Visible - IR

12. UV – Visible - IR

13. Wavelength dependent treatment depth

14. Spectrum and Penetration depth
Spectrum of radiation
* **
Visible light
UV light IR light
x-rays Thermal radiation
Cosmic radiation
TV Radio
MedSolution LPT devices:
•‫‏‬Wavelength:‫‏‬combination‫‏‬of‫‏‬
red* & infrared**
Red: for indications on the surface
infrared: for deep laying indications

15. Treatment depth versus treatment time

16. The ATP synthesis
ATP (Adenosine-Tri-Phosphate): the
molecular energy for each cell of the body
and the skin.
It is built in the mitochondria, the power
station in each cell. The light is absorbed
by components of the cellular respiratory
chain namely cytochrome c oxidase (COX).
If there is too less ATP available, the cell Mitochondria
cannot follow its functions 100%
LaserCat & PalmLaser bring energy to the
mitochondria where it is used to produce
more ATP - which means new energy for
the cell.
Regeneration of the cell, the tissue and the
body can be seen already after a few
treatments.

17. Biochemical effects
• LPT increases the ATP synthesis min 150 %
==> biostimulation / regeneration of tissue
==> reduction of inflammation
==> relief of pain
•‫‏‬LPT‫‏‬stimulates‫‏‬the‫‏‬collagen‫‏‬production‫‏>==‏‬improved‫‏‬tissue‫‏‬regeneration
•‫‏‬LPT‫‏‬supports‫‏‬the‫‏‬blood‫‏‬flow,‫‏‬lymphatic‫‏‬flow‫‏‬and‫‏‬metabolism‫‏>==‏‬more‫‏‬nutrients,‫‏‬more‫‏‬oxygen,‫‏‬
more blood cells are available for an increased healing and regeneration, swellings are reduced
•‫‏‬LPT‫‏‬stimulates‫‏‬the‫‏‬RNA-, DNA- & protein synthesis ==> improved cell regeneration

18. Enhancement of ATP production

19. Arndt-Schultz-Law
Biphasic dose response in measured difference in integrated area
under the curve of time course of wound size compared to no
treatment control, with a clear maximum seen at 2 J/cm2, and the high
dose of 50 J/cm2 gave a worsening of the wound healing time
*Dose Response. 2009; 7(4): 358–383.
Published online 2009 September 1. doi: 10.2203/dose-response.09-
027.Hamblin, PMCID: PMC2790317
Biphasic Dose Response in Low Level Light Therapy
Ying-Ying Huang, Aaron C.-H. Chen, James D. Carroll, Michael R.

20. Pain versus time
Pain
Time

21. Effects on wound healing
- Enhanced DNA and RNA synthesis *
- Stimulation of mitosis **
- Accelerated tissue regeneration ***
* M.Dyson, S.Young: Effect of laser therapy on wound contraction and cellularity an mice. In:
Lasers Med.Sci. 1/1982, S.125-130
* Tiina Karu: Molecular mechanism of the therapeutic effect of low-intensity laser irradiation. In:
Lasers Life Sci. 2/1988, S.53-74
* V.Manteifel u.a.: Activation of transcription in lymphocytes after exposure to a He-Ne laser. In:
Mol.Biol. 24/1990, S.860-867
*,G.Danhof: Biological effects of the laser beam. In: Lasers in Medicine and Dentistry. Zagreb
2000, S.127-152
** Tiina Karu: Mechanisms of Low-Power Laser Light Action on cellular Level In: Lasers in
Medicine and Dentistry.Zagreb 2000, S.97-125
** O.A. Tiphlova und Tiina Karu: Role of primary photoacceptors in low-power laser
effects:action of He-Ne Laser radiation on bacteriophage T4 - Escheria coli interaction. In:
Lasers Surg.Med. 9/1989, S.67-69
*** N.Ben-Dov. u.a.: Low-energy laser irradiation affect satellite cellproliferation and
differentiation in vitro. In: Biochem.Biophys.Acta. 3/1999, S.372-380
*** A.Mester u.a.: Open wound healing - bed sores, ulcus cruris, burns - with systemic effects of
LLLT. In: Lasers in Medicine and Dentistry. Zagreb 2000
*** V.d.Veen, P.Lievens: Low level laser therapy (LLLT): the influence on the proliferation of
fibroblasts and the Influence on the regeneration process of lymphatic, muscular and cartilage
tissue. In: Lasers in Medicine and Dentistry. Zagreb 2000, S.187-217

22. Application in Medicine - examples
Dermatology / General Medicine Dental Medicine
plastic surgery Acute injuries Acid & Grinding Trauma
Abrasions Arthrosis Aphtae
Acute injuries Gout Dentitio difficilis
Allergies Neuralgiform pain Extraction wounds
Burns Panarteriitis Lockjaw
Decubiti Tinnitus Nausea
Fresh scars & keloids Trigeminusneuralgi Paradontosis
Hematoma after surgery a Stomatitis
Wounds Temporomandibular- jaw
Herpes Zoster, H.
pain
Labialis Orthopaedics Dental root hyper-
Post surgical pain Carpal Tunnel Syndrome sensibilities
Ulcus Cruris Distortion
Urticaria Epicondylitis
Wounds Fibromyalgia
Ischialgia
Lumbago
Muscular Induration
Post surgical pain
Shoulder-Arm-Syndrome

23. Contraindications / Precautions
 Patientes with cardiac pacemaker in the area of the thorax
 Pregnant women in the area of the abdomen
 Patients with cancer
 Skin diseases without diagnose
 Epilepsy patients
no radiation on:
 Open eyes
 Thyroid gland
 Solar Plexus
 Child's epiphysis
 Open fontanel of infants

24. Side effects
The Laser Photo Therapy has only very few side effects:
The treatment effect can be:
• A little tingeling in the treated area
• A warm feeling in the treated area (blood flow!)‫‏‬
• A higher sensitivity in open wounds
• If too much energy is used, a surpressing effect can take place
Further there can be
• Some tiredness
• Increased sweating

25. Why should I start using LPT – New Paradigma
Very broad indication range of LPT
&
No or negligible side effects
->
Trade off between beneficial effect and side effects
always in favour of treatment
->
Therapy possible without secure diagnosis

26. Safety considerations
Eye protection
Parallel laser beams are of great danger for the
eyes. The beam can be focused by the eyes and
damage the retina irreparable ! (Class 3b & 4
lasers)‫‏‬
Laser light which is coming through the closed
eyes is not dangerous as the light is not focused, it
is diffuse.
PalmLaser are class 1M lasers and emit a
divergent beam, which becomes only danger, by
looking into it directly for more than 100 seconds.
A divergent beam can not be re-focused by the
eyes. Therefore PalmLaser are much safer than
class 3b lasers.
There are no precaution actions necessary for a
class 1M laser.

27. Specification of PalmLaser
PalmLaser:
combination of cw lasers
red & IR
Laser 1
Power Red laser 650 nm, 20 mW
in mW
cw = continuous wave
Time in nsec
Laser 2
Power
in mW IR laser 785 nm, 80 mW
cw = continuous wave
Time in nsec

28. PL - Safety
Laserclass 1M:
 No protection goggle
 No laser safety course
 No special precautions required

29. PalmLaser
•If the red battery control LED
lights up, PalmLaser needs to
be charged. There are approx 5
minutes left to finish the
treatment.
•During charging PalmLaser, a
green LED lights up till the
charging process is finished.
Charging time - approx. 3 h
Treatment time - approx. 1 h

30. PL & PL professional - accessories
PalmLaser / PalmLaser professional comes with the following
accessory:
•PalmLaser
•Operation manual
•Battery charger
•Case
•Accumulators (inside PalmLaser)‫‏‬

31. PL & PL professional - Application
•‫‏‬Muscle-lesions •‫‏‬Arthrosis
•‫‏‬Edema •‫‏‬Rheumatoid arthritis
•‫‏‬Swellings •‫‏‬Myalgia
•‫‏‬Bursitis •‫‏‬Decubitus ulcers, Pressure sores
•‫‏‬Tendinopathies •‫‏‬Circulatory disorder
•‫‏‬Tenosynovitis •‫‏‬Diabetic foot
•‫‏‬Distortions, contusions, sprains •‫‏‬Ulcus cruris, Leg ulcers
•‫‏‬Capsulo-ligamentar lesions •‫‏‬Back pain
•‫‏‬Abrasions •‫‏‬Shoulder-arm-syndrome, Frozen
•‫‏‬Fractures shoulder
•‫‏‬Iliotibial‫‏‬band‫‏‬syndrome‫(‏‬runner‘s‫‏‬ •‫‏‬Tension, stiffness
knee) •‫‏‬Carpal-tunnel-syndrome
•‫‏‬Traumas •‫‏‬Fall-related injuries

32. Application
CTS Knee Shoulder
Head

33. Application

34. Application

35. Application

36. PalmLaser– Application Dr. Rarreck
The application is as
easy as with LaserCat.
After adjusting the time
due to the
recommendations in the
manual
Or against own
experience, the diffusor Dr. Rarreck, FC Schalke 04
can be set on the skin
and
The treatment can be
started.
The diffusor shall stay
in contact with the skin
to avoid too much
loss by reflections.
Exception: open
Jörg Blüthmann, Physiotherapist
wounds.
Hertha BSC Berlin
PalmLaser shall be
moved slowly over the

37. PL– Application Schalke 04

38. PL – Application Schalke 04

39. PL– Application Schalke 04

40. Self-Treatment

41. Veterinary use

42. Advantages of LPT with LaserCat &
PalmLaser
Easy operation
Two wavelength in one machine
Class 1M laser
Pre-set program in LaserCat
Mobile use with PalmLaser & SilkLite
No protection goggle needed
No harm to the skin/tissue, no heat
For acute & chronic diseases

43. Advantages for the doctor´s
practice using LPT
•‫‏‬Highly‫‏‬profitable‫‏‬already‫‏‬with‫ 3-2‏‬patients
PalmLaser delivers highly effective laser- phototherapy and represents a lucrative
proposition to professionals. Performing regular therapy sessions on 2 -3 patients per
month breaks the threshold of profitability.
•‫‏‬Patient‫‏‬loyalty‫‏‬and‫‏‬acquisition‫‏‬tool
Offering and delivering effective and safe innovative therapies elevates the image of
the practice, leading to long term patient loyalty and patient recommendation based
increase in popularity.
•‫‏‬Using‫‏‬your‫‏‬assistant‫‏‬to‫‏‬the‫‏‬full‫‏‬potential
PalmLaser treatment is easy to perform and can be delegated to less qualified, but well
trained‫‏‬assistants,‫‏‬thus‫‏‬freeing‫‏‬the‫‏‬valuable‫‏‬doctor‘s‫‏‬time‫‏‬for‫‏‬other‫‏‬duties‫‏‬and‫‏‬tasks.
The assistants can dedicate more time to the patients, thoroughly explaining the thera-
py and providing as much personal care and attention as the patients desire.
Further the motivation and qualification of the assistant will increase.
•‫‏‬Enhancing‫‏‬your‫‏‬therapy‫‏‬systems
Ability to perform laser-phototherapy guarantees a real USP advantage for your practice.
Despite its proven efficacy and safety, laser-phototherapy is not yet widely spread
due to the past difficulties with early lasers (i.e. complexity, size and high costs).
PalmLaser from MedSolution provides a practical and affordable solution to the pro-
blems of the past, making laser-phototherapy accessible, affordable and well within
your reach!
As a part of modern therapeutic approach PalmLaser is an effective and safe therapeu-
tic solution to many health problems.

44. Advantages for the patient using LPT
•‫‏‬Highly‫‏‬efficient
PalmLaser delivers highly powerful and potent laser therapy for acute or chronic medical
conditions. PalmLaser supports an array of healing processes at cellular level and signifi-
cantly accelerates regeneration. Pain and inflammation reduce swiftly.
•‫‏‬No‫‏‬side‫‏‬effects‫ –‏‬highly efficient treatment method
Today‘s patient is well informed and demands interventions that are effective,safe and
without side effects or treatment related harms. Therapy with PalmLaser is safe and pain-
less. Side effects have never been noted. PalmLaser is a stand alone therapeutic modality
or can be used in synergy with other therapies, such as physiotherapy or prescription
medicines. In some conditions, PalmLaser can entirely replace or largely reduce the need
for other therapeutic interventions.
•‫‏‬Fast‫‏‬recovery
Laser-phototherapy helps athletes to return to training or competition faster or without
excessively long delay. Portability of PalmLaser allows the treatment to commence
immediately after the trauma has occurred – The immediate post trauma application of
laser therapy is the most effective way of dealing with injuries for optimum healing and
fast recovery.
•‫‏‬Premium‫‏‬therapy‫‏‬for‫‏‬supporting‫‏‬the‫‏‬somatic‫‏‬self-healing mechanisms
Laser-phototherapy is a natural and modern therapy that is recognised and appreciated
by many people. Older and the elderly patients in particular value the features and the
benefits of laser-phototherapy. Laser-phototherapy is effective, yet gentle and non-trau-
matising. It activates self healing, regeneration and restoration. Improvements achieved
with PalmLaser phototherapy can be life changing and giving new leases to

45. Example – diabetic foot ulcer
LaserWorld Guest Editorial, Nr 13 - 2000.
The mangement of diabetic neuropathic
ulceration by HeNe laser.
The following photo sequence has been contributed by Dr.
Ali Abaci, Turkey
The main effects of the LLLT helps the patient in terms of
-> skin regeneration
-> wound healing
-> blood circulation
Treatment parameters for the diabetic neuropathic ulceration are given below : He-Ne Laser,
wavelength 632 nm. Continuous Wave Beam Area(cm2)= Diameter(cm)2 x 0.7854 = (3.1 x 3.1)
x 0.7854 = 7.547 cm2 Laser Output Power = 5 mW= 0.005 W Laser Output Power(W) Power
Density(W/cm2)= Beam Area(cm2) 0.005 == 0.0006625 W/cm2 7.547 Energy Density(J/cm2)=
Power Density(W/cm2) x Time(sec) = 0.0006625 x 600 = 0.3975 J/cm2 = ~ 0.4 J/cm2.
Treatments were given once a day, 5 days a week, totally for 4 weeks

46. Example – Diabetic Foot Surgery I
Chief Surgeon & SAFDAP: Dr. Abdulazizi Al-Qannass
Podiatry Surgery Team – Riyadhh:
SAFDAP Assistant Ms. Jazwa Al-Otaibi
Mr. Matthew Mallon
Mr. Mumdoh Mnwar
Case: 42 old Male, suffering
from Obesity and Diabetic
Type II. Come to the clinic
with highly affected toe in the
right foot, amputation needed
for the fifth toe. On
medication Hypo Glacimic,
after amputation started on
Insulin.
Foot after fourth session
with PalmLaser:
Pus from tunnel wound
Dry tissue and dark color
Wound is closing

47. Example – Diabetic Foot Surgery II
The after amputation wound was under treatment with antibiotic for 3
months, wound did not heal and foot skin color was dark and did not get
well, the patient was under stress and pain.
Low Level Laser Therapy was
decided to be applied by
PalmLaser, 5min, each
session, day after day,
3sessions per week. The time
frame of treatment set to 30
Days.
Foot afer 13 sessions with
PL:
Tissue and skin heal from
necrotic stage.
Wound completely heal from
infection and wound is close
with no pain.
Foot tissue and blood
circulation are back to
normal.