Many of the major disruptions in media and communications have been driven by nimble, entrepreneurial companies, coming out of nowhere to completely decimate established business models. Companies that spin into existence to solve one problem or commercialize a single idea can scale almost instantly if they find a solution that sticks. That’s what’s happening all over the marketing industry today: hundreds of tech-savvy startups are reinventing business from the bottom up.
For Life Sciences, the Future of Master Data Management is in the CloudCognizant
Cloud-based MDM is cost-effective and easily implemented; it is scalable, robust and mature; and it has the flexibility required to enable and support the evolving transformation of life sciences commercial operations.
Accenture Digital Health Technology Vision 2018accenture
Explore Accenture's Digital Health Tech Vision 2018 report, showcasing five health IT trends that are going to redefine how intelligent enterprises of the future will work.
Dare to be Different: Revamping Collaboration in Life Sciences Contract Manuf...accenture
Contract Manufacturing Organizations expansion has made the supply chain harder to manage for both life sciences companies and contract suppliers. Advanced digital technologies can enable a new era of supply chain collaboration. Visit https://accntu.re/2UVVP9F to learn more.
Many of the major disruptions in media and communications have been driven by nimble, entrepreneurial companies, coming out of nowhere to completely decimate established business models. Companies that spin into existence to solve one problem or commercialize a single idea can scale almost instantly if they find a solution that sticks. That’s what’s happening all over the marketing industry today: hundreds of tech-savvy startups are reinventing business from the bottom up.
For Life Sciences, the Future of Master Data Management is in the CloudCognizant
Cloud-based MDM is cost-effective and easily implemented; it is scalable, robust and mature; and it has the flexibility required to enable and support the evolving transformation of life sciences commercial operations.
Accenture Digital Health Technology Vision 2018accenture
Explore Accenture's Digital Health Tech Vision 2018 report, showcasing five health IT trends that are going to redefine how intelligent enterprises of the future will work.
Dare to be Different: Revamping Collaboration in Life Sciences Contract Manuf...accenture
Contract Manufacturing Organizations expansion has made the supply chain harder to manage for both life sciences companies and contract suppliers. Advanced digital technologies can enable a new era of supply chain collaboration. Visit https://accntu.re/2UVVP9F to learn more.
Biopharma is facing compressive disruption that could impact traditional approaches. Find out how New Science can reshape the biopharma landscape and patient care. Visit http://www.accenture.com/newscience to learn more.
The 2016 Strategic Hospital Priorities Study examines the current direction of the industry and, in particular, how Medtech companies can capitalize on the many needs of hospital administrators.
While the healthcare market has steadily evolved since L.E.K. Consulting issued its first hospital study in 2010, many of the same trends remain in place — among them consolidation, non-acute care integration, accountability, technology enhancements and novel pricing schemes.
This Executive Insights addresses a number of key topics, including:
Hospital administrator’s chief priorities
Most valuable medtech services
Focus on IT spending
Outlook for outsourcing
Accenture's six-country survey among 180 C-level health executives says adoption of AI is measured, but real.
The survey assessed beliefs about market maturity, practical and clinical challenges to the adoption of AI in healthcare.
Enthusiasm for AI (artificial intelligence) is high among health executives, with people skills the most important implementation success factor.
Sufficient staff training/ expertise is rated the most important success factors for AI implementation (ranked in top three by 73 percent of execs).
Visit https://accntu.re/2T4KuXb to learn more.
2019 Accenture Global Financial Services Consumer Study: Persona Infographicaccenture
Are your financial consumers Pioneers, Pragmatists, Skeptics or Traditionalists? View our infographic for an illustration of each persona. Our latest research surveyed 47,000 customers to uncover the consumer trends affecting banks and insurers today. Want to know what banking and insurance customers value? What differentiates them and how they want to engage with their financial providers? Download our report to learn more: https://accntu.re/2F9sPFS
Our INTIENT Clinical suite of tools provides simplified collection, cleansing and management of clinical data, as well as faster, improved access through smart analytics and intelligent data flow. Visit https://accntu.re/2Eaov8N to learn more.
Accenture 2015 Global Risk Management Study: Risk Masters infographicaccenture
Accenture’s 2015 Global Risk Management Study explored the risk management function across all financial services industries, finding some characteristics that are common among the top 10 percent of risk leaders—known as risk masters.
Faster and Cheaper Clinical Trials: The Benefit of Synthetic Dataaccenture
Take the innovation leap: Four things pharma companies can do now for a synthetic data-driven approach to clinical trial design. https://accntu.re/3vjVjVs
The Industry’s Move Toward Digitally Connected Clinical TrialsVeeva Systems
The rapid adoption of decentralized trials is causing significant challenges – sites are burdened by too many technologies and the use of multiple patient-facing applications adds complexity for patients.
In these slides, we discuss the implications of decentralized trials, share findings from the Veeva Digital Clinical Trials Survey, and explore how clinical leaders are accelerating digital transformation to make studies more site and patient-centric.
Access the Veeva Digital Clinical Trials Survey Report (https://bit.ly/35eAeDn) for additional insights from more than 280 clinical leaders worldwide on the industry’s progress toward digital trial strategies, lessons learned, and what lies ahead.
Unleashing Innovation: A Closer Look at Impacts & Benefitsaccenture
Using our Innovation Framework, Accenture conducted a global study of government innovation. Here we focus on the Strategy pillar of Impact & Benefits. Learn more: https://accntu.re/2IzGkSP
Losing the Cyber Culture War in Healthcare: Accenture 2018 Healthcare Workfor...accenture
Accenture surveyed employees of provider and payer organizations in the United States and Canada to understand health employee attitudes and behaviors related to cybersecurity practices.
AstraZeneca: A Vision for a Collaborative Clinical EnvironmentVeeva Systems
Slides from AstraZeneca's 2019 Veeva R&D Summit presentation.
After receiving the 2018 Eagle Award for the best sponsor by the Society for Clinical Research Sites (SCRS), AstraZeneca is on an ongoing quest to remain a sponsor of choice for 2019 and beyond. Learn how they are leveraging technology, a unified clinical trial platform, and other strategies to simplify trial conduct at sites.
Your cognitive future: How next-gen computing changes the way we live and workIBM in Healthcare
The healthcare industry is undergoing significant change driven by six disruptive forces - rapid digitization, changing consumer expectations, regulatory complexities, increasing healthcare demand, shortage of skilled resources and elevating healthcare costs. To meet the implication of these forces, healthcare organizations must excel in engaging with consumers, discovering new ideas and taking effective decisions
Currently, traditional analytics capabilities are unable to exploit maximum value from the ever increasing data resource constraining organization’s achievements and performance. But cognitive computing has the ability to bridge this gap and can open up fresh opportunities for the healthcare industry. It is already helping healthcare organizations to provide personalized care, effective decisions and more innovative solutions.
Regulatory Compliance: Automated Digital Assistantaccenture
Accenture’s Regulatory and Compliance Automated Digital Assistant identifies an employee using facial recognition and provides them real-time access to a compliance knowledge base. Read our brochure.
Healthcare Innovation Technology Group MeetingDavid Voran
Presentation to a Kansas City Healthcare Innovation Technology Group Meeting on June 28, 2011.
Describes Innovation processes, needs, some examples and advice for those creating innovative technology products to be used in Healthcare.
Data-driven Healthcare for ManufacturersLindaWatson19
Medical Device Equipment and Hospital Supplies Manufacturers also face increased pressure to comply with strict regulatory procedures to ensure patient safety. Product transparency and efficient end-to-end processes that optimize the manufacturing process and decision making are very important.
Biopharma is facing compressive disruption that could impact traditional approaches. Find out how New Science can reshape the biopharma landscape and patient care. Visit http://www.accenture.com/newscience to learn more.
The 2016 Strategic Hospital Priorities Study examines the current direction of the industry and, in particular, how Medtech companies can capitalize on the many needs of hospital administrators.
While the healthcare market has steadily evolved since L.E.K. Consulting issued its first hospital study in 2010, many of the same trends remain in place — among them consolidation, non-acute care integration, accountability, technology enhancements and novel pricing schemes.
This Executive Insights addresses a number of key topics, including:
Hospital administrator’s chief priorities
Most valuable medtech services
Focus on IT spending
Outlook for outsourcing
Accenture's six-country survey among 180 C-level health executives says adoption of AI is measured, but real.
The survey assessed beliefs about market maturity, practical and clinical challenges to the adoption of AI in healthcare.
Enthusiasm for AI (artificial intelligence) is high among health executives, with people skills the most important implementation success factor.
Sufficient staff training/ expertise is rated the most important success factors for AI implementation (ranked in top three by 73 percent of execs).
Visit https://accntu.re/2T4KuXb to learn more.
2019 Accenture Global Financial Services Consumer Study: Persona Infographicaccenture
Are your financial consumers Pioneers, Pragmatists, Skeptics or Traditionalists? View our infographic for an illustration of each persona. Our latest research surveyed 47,000 customers to uncover the consumer trends affecting banks and insurers today. Want to know what banking and insurance customers value? What differentiates them and how they want to engage with their financial providers? Download our report to learn more: https://accntu.re/2F9sPFS
Our INTIENT Clinical suite of tools provides simplified collection, cleansing and management of clinical data, as well as faster, improved access through smart analytics and intelligent data flow. Visit https://accntu.re/2Eaov8N to learn more.
Accenture 2015 Global Risk Management Study: Risk Masters infographicaccenture
Accenture’s 2015 Global Risk Management Study explored the risk management function across all financial services industries, finding some characteristics that are common among the top 10 percent of risk leaders—known as risk masters.
Faster and Cheaper Clinical Trials: The Benefit of Synthetic Dataaccenture
Take the innovation leap: Four things pharma companies can do now for a synthetic data-driven approach to clinical trial design. https://accntu.re/3vjVjVs
The Industry’s Move Toward Digitally Connected Clinical TrialsVeeva Systems
The rapid adoption of decentralized trials is causing significant challenges – sites are burdened by too many technologies and the use of multiple patient-facing applications adds complexity for patients.
In these slides, we discuss the implications of decentralized trials, share findings from the Veeva Digital Clinical Trials Survey, and explore how clinical leaders are accelerating digital transformation to make studies more site and patient-centric.
Access the Veeva Digital Clinical Trials Survey Report (https://bit.ly/35eAeDn) for additional insights from more than 280 clinical leaders worldwide on the industry’s progress toward digital trial strategies, lessons learned, and what lies ahead.
Unleashing Innovation: A Closer Look at Impacts & Benefitsaccenture
Using our Innovation Framework, Accenture conducted a global study of government innovation. Here we focus on the Strategy pillar of Impact & Benefits. Learn more: https://accntu.re/2IzGkSP
Losing the Cyber Culture War in Healthcare: Accenture 2018 Healthcare Workfor...accenture
Accenture surveyed employees of provider and payer organizations in the United States and Canada to understand health employee attitudes and behaviors related to cybersecurity practices.
AstraZeneca: A Vision for a Collaborative Clinical EnvironmentVeeva Systems
Slides from AstraZeneca's 2019 Veeva R&D Summit presentation.
After receiving the 2018 Eagle Award for the best sponsor by the Society for Clinical Research Sites (SCRS), AstraZeneca is on an ongoing quest to remain a sponsor of choice for 2019 and beyond. Learn how they are leveraging technology, a unified clinical trial platform, and other strategies to simplify trial conduct at sites.
Your cognitive future: How next-gen computing changes the way we live and workIBM in Healthcare
The healthcare industry is undergoing significant change driven by six disruptive forces - rapid digitization, changing consumer expectations, regulatory complexities, increasing healthcare demand, shortage of skilled resources and elevating healthcare costs. To meet the implication of these forces, healthcare organizations must excel in engaging with consumers, discovering new ideas and taking effective decisions
Currently, traditional analytics capabilities are unable to exploit maximum value from the ever increasing data resource constraining organization’s achievements and performance. But cognitive computing has the ability to bridge this gap and can open up fresh opportunities for the healthcare industry. It is already helping healthcare organizations to provide personalized care, effective decisions and more innovative solutions.
Regulatory Compliance: Automated Digital Assistantaccenture
Accenture’s Regulatory and Compliance Automated Digital Assistant identifies an employee using facial recognition and provides them real-time access to a compliance knowledge base. Read our brochure.
Healthcare Innovation Technology Group MeetingDavid Voran
Presentation to a Kansas City Healthcare Innovation Technology Group Meeting on June 28, 2011.
Describes Innovation processes, needs, some examples and advice for those creating innovative technology products to be used in Healthcare.
Data-driven Healthcare for ManufacturersLindaWatson19
Medical Device Equipment and Hospital Supplies Manufacturers also face increased pressure to comply with strict regulatory procedures to ensure patient safety. Product transparency and efficient end-to-end processes that optimize the manufacturing process and decision making are very important.
Data-Driven Healthcare for Manufacturers Amit Mishra
Data-driven healthcare empowers the providers with a common data platform to discover untapped data-driven opportunities. Healthcare data and its impact on the patient care decision process via accurate, real-time, reliable data from disparate sources is creating a digital health revolution. Physician groups, nursing facilities, hospitals, pharmaceutical companies, clinical researchers, and medical equipment manufacturers are all churning out vast amounts of data during their daily operations. This data has tremendous value and can revolutionize patient care, diagnosis, real-time decisions and help deliver new, unimagined innovations with quality of patient care. Know more about data-driven healthcare at https://www.solix.com/solutions/data-driven-solutions/healthcare/
The Randomized Controlled Trial: The Gold Standard of Clinical Science and a ...marcus evans Network
Tim Fayram, St. Jude Medical Inc. - Speaker at the marcus evans Medical Device R&D Summit Fall 2013, held in Palm Beach, FL delivered his presentation entitled The Randomized Controlled Trial: The Gold Standard of Clinical Science and a Barrier to Innovation?
The Work Ahead in Life Sciences: Cures at the Speed of DigitalCognizant
Life sciences businesses have accelerated their digital-first journey to operate in a world where time-to-everything matters more than any other strategic imperative, according to our study.
Why is Pharmacovigilance required in pharmaceutical markets for all countries? Majorly it is due to adverse drug reactions (ADR) that lead to severe illness, permanent side effects, and even death.
Integrate RWE into clinical developmentIMSHealthRWES
With greater application of RWE throughout the pharmaceutical
lifecycle, learnings are emerging that offer guidance for
approaches to derive the maximum value. This article captures
the author’s experience at a leading international biotech, with
insights for smoothing RWE assimilation into clinical
development and realizing the benefits it brings.
A hybrid approach to data management is emerging in healthcare as organizations recognize the value of an enterprise data warehouse in combination with a data lake.
In this SlideShare, we discuss data lakes in healthcare and we:
Provide an overview of a Hadoop-based data lake architecture and integration platform, and its application in machine learning, predictive modeling, and data discovery
Discuss several key use cases driving the adoption of data lakes for both providers and health plans
Discuss available data storage forms and the required tools for a data lake environment
Detail best practices for conducting data lake assessments and review key implementation considerations for healthcare
The FDA Digital Health Center of Excellence and the Advancement of Digital He...Greenlight Guru
The FDA Digital Health Center of Excellence is part of the planned evolution of the digital health program with the intent to drive synergy for digital health efforts, align strategy with implementation, prepare the FDA for the digital health future, and protect patients and maintain the FDA standards of safety and effectiveness.
Ultimately, the program works to strategically advance science and evidence for digital health technologies that meets the needs of
stakeholders.
This free in-depth webinar, presented by Matthew DiamondChief Medical Officer, Digital Health Center of Excellence, will cover the digital health landscape and areas of application, goals and outcomes, planned services and launch plan, and the current areas of focus - including AI/ML-Based SaMD.
This presentation originally aired during the 2021 State of Medical Device Virtual Summit.
Clinical trial data wants to be free: Lessons from the ImmPort Immunology Dat...Barry Smith
Presentation to the Clinical and Research Ethics Seminar, Clinical and Translational Science Center, Buffalo, January 21, 2014
https://immport.niaid.nih.gov/
http://youtu.be/booqxkpvJMg
MPG Life Sciences Software Market Snapshot October 2020Madison Park Group
We are pleased to present our life sciences software market snapshot for October 2020.
Madison Park Group is a unique investment banking firm that takes a "strategy first" approach to advising software companies. Our partners have developed and advised numerous successful companies as operators, investors and investment bankers.
Rohan Khanna, Jonathan Adler and James Tomasullo spearhead the firm's efforts in the space.
Similar to The power of a digital thread in life sciences (20)
Engineering Services: con gli ingegneri per creare valore sostenibileaccenture
Collaboriamo con gli ingegneri di aziende capital intensive per combinare tecnologie innovative con un approccio pragmatico che aiuti a raggiungere risultati aziendali migliori.
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
UiPath Test Automation using UiPath Test Suite series, part 3DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 3. In this session, we will cover desktop automation along with UI automation.
Topics covered:
UI automation Introduction,
UI automation Sample
Desktop automation flow
Pradeep Chinnala, Senior Consultant Automation Developer @WonderBotz and UiPath MVP
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdfPaige Cruz
Monitoring and observability aren’t traditionally found in software curriculums and many of us cobble this knowledge together from whatever vendor or ecosystem we were first introduced to and whatever is a part of your current company’s observability stack.
While the dev and ops silo continues to crumble….many organizations still relegate monitoring & observability as the purview of ops, infra and SRE teams. This is a mistake - achieving a highly observable system requires collaboration up and down the stack.
I, a former op, would like to extend an invitation to all application developers to join the observability party will share these foundational concepts to build on:
Encryption in Microsoft 365 - ExpertsLive Netherlands 2024Albert Hoitingh
In this session I delve into the encryption technology used in Microsoft 365 and Microsoft Purview. Including the concepts of Customer Key and Double Key Encryption.
UiPath Test Automation using UiPath Test Suite series, part 4DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 4. In this session, we will cover Test Manager overview along with SAP heatmap.
The UiPath Test Manager overview with SAP heatmap webinar offers a concise yet comprehensive exploration of the role of a Test Manager within SAP environments, coupled with the utilization of heatmaps for effective testing strategies.
Participants will gain insights into the responsibilities, challenges, and best practices associated with test management in SAP projects. Additionally, the webinar delves into the significance of heatmaps as a visual aid for identifying testing priorities, areas of risk, and resource allocation within SAP landscapes. Through this session, attendees can expect to enhance their understanding of test management principles while learning practical approaches to optimize testing processes in SAP environments using heatmap visualization techniques
What will you get from this session?
1. Insights into SAP testing best practices
2. Heatmap utilization for testing
3. Optimization of testing processes
4. Demo
Topics covered:
Execution from the test manager
Orchestrator execution result
Defect reporting
SAP heatmap example with demo
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
Welocme to ViralQR, your best QR code generator.ViralQR
Welcome to ViralQR, your best QR code generator available on the market!
At ViralQR, we design static and dynamic QR codes. Our mission is to make business operations easier and customer engagement more powerful through the use of QR technology. Be it a small-scale business or a huge enterprise, our easy-to-use platform provides multiple choices that can be tailored according to your company's branding and marketing strategies.
Our Vision
We are here to make the process of creating QR codes easy and smooth, thus enhancing customer interaction and making business more fluid. We very strongly believe in the ability of QR codes to change the world for businesses in their interaction with customers and are set on making that technology accessible and usable far and wide.
Our Achievements
Ever since its inception, we have successfully served many clients by offering QR codes in their marketing, service delivery, and collection of feedback across various industries. Our platform has been recognized for its ease of use and amazing features, which helped a business to make QR codes.
Our Services
At ViralQR, here is a comprehensive suite of services that caters to your very needs:
Static QR Codes: Create free static QR codes. These QR codes are able to store significant information such as URLs, vCards, plain text, emails and SMS, Wi-Fi credentials, and Bitcoin addresses.
Dynamic QR codes: These also have all the advanced features but are subscription-based. They can directly link to PDF files, images, micro-landing pages, social accounts, review forms, business pages, and applications. In addition, they can be branded with CTAs, frames, patterns, colors, and logos to enhance your branding.
Pricing and Packages
Additionally, there is a 14-day free offer to ViralQR, which is an exceptional opportunity for new users to take a feel of this platform. One can easily subscribe from there and experience the full dynamic of using QR codes. The subscription plans are not only meant for business; they are priced very flexibly so that literally every business could afford to benefit from our service.
Why choose us?
ViralQR will provide services for marketing, advertising, catering, retail, and the like. The QR codes can be posted on fliers, packaging, merchandise, and banners, as well as to substitute for cash and cards in a restaurant or coffee shop. With QR codes integrated into your business, improve customer engagement and streamline operations.
Comprehensive Analytics
Subscribers of ViralQR receive detailed analytics and tracking tools in light of having a view of the core values of QR code performance. Our analytics dashboard shows aggregate views and unique views, as well as detailed information about each impression, including time, device, browser, and estimated location by city and country.
So, thank you for choosing ViralQR; we have an offer of nothing but the best in terms of QR code services to meet business diversity!
Builder.ai Founder Sachin Dev Duggal's Strategic Approach to Create an Innova...Ramesh Iyer
In today's fast-changing business world, Companies that adapt and embrace new ideas often need help to keep up with the competition. However, fostering a culture of innovation takes much work. It takes vision, leadership and willingness to take risks in the right proportion. Sachin Dev Duggal, co-founder of Builder.ai, has perfected the art of this balance, creating a company culture where creativity and growth are nurtured at each stage.
Le nuove frontiere dell'AI nell'RPA con UiPath Autopilot™UiPathCommunity
In questo evento online gratuito, organizzato dalla Community Italiana di UiPath, potrai esplorare le nuove funzionalità di Autopilot, il tool che integra l'Intelligenza Artificiale nei processi di sviluppo e utilizzo delle Automazioni.
📕 Vedremo insieme alcuni esempi dell'utilizzo di Autopilot in diversi tool della Suite UiPath:
Autopilot per Studio Web
Autopilot per Studio
Autopilot per Apps
Clipboard AI
GenAI applicata alla Document Understanding
👨🏫👨💻 Speakers:
Stefano Negro, UiPath MVPx3, RPA Tech Lead @ BSP Consultant
Flavio Martinelli, UiPath MVP 2023, Technical Account Manager @UiPath
Andrei Tasca, RPA Solutions Team Lead @NTT Data
PHP Frameworks: I want to break free (IPC Berlin 2024)Ralf Eggert
In this presentation, we examine the challenges and limitations of relying too heavily on PHP frameworks in web development. We discuss the history of PHP and its frameworks to understand how this dependence has evolved. The focus will be on providing concrete tips and strategies to reduce reliance on these frameworks, based on real-world examples and practical considerations. The goal is to equip developers with the skills and knowledge to create more flexible and future-proof web applications. We'll explore the importance of maintaining autonomy in a rapidly changing tech landscape and how to make informed decisions in PHP development.
This talk is aimed at encouraging a more independent approach to using PHP frameworks, moving towards a more flexible and future-proof approach to PHP development.
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
Quantum Computing: Current Landscape and the Future Role of APIs
The power of a digital thread in life sciences
1. October 13, 2021
Stuart Henderson
Dan Sheeran
Barry Heavey
Chris Kopinski
The power of
a digital thread
in life sciences
2. Setting a new pace of change
The lessons of the last
year can help power
the discovery,
development and
delivery of new
treatments for all health
conditions. • Phase II and III protocol procedures have
increased 44% since 2009,
• Patient stratification and novel
biomarkers/endpoints driving a rise in trial
complexity.
More treatments
in development
+ market
stratification
• AI-based methodologies reduce time spent for
discovery from 4.5 years to a year.
• Virtual clinical trials grew by over 50%
in 2020.
• Average treatment duration of decentralized
trials was 36% (140 days) faster
Treatments are
coming to market
faster than ever
• Driving 81% of biopharma revenue growth and
61% of all revenues (2021-2026).
• The average NPV of New Science treatments to
be launched from 2022-2026 will exceed
traditional counterparts by 69%.
New Science
is more important
than ever
3. COVID-19 highlighted many orthodoxies
within life sciences that have now been dispelled
Orthodoxy 1
We can’t change the
way we discover
medicine
Orthodoxy 2
We can’t deviate from
in-person clinical
trials, at premier sites
Orthodoxy 3
We can’t rapidly scale
manufacturing for new
modalities
4. What if we could…
Accelerate
early process
development
Accelerate filing
and approval of the
CMC dossier
Execute flawless
tech transfer of
manufacturing process
between teams
Optimize and speed
the manufacturing
process
5. Digital thread
in life sciences
A digital solution thataccelerates thescale up in
supply of complex treatmentsfrom clinical trials
through commercial launch and production.
By building upon established tools, this creates
better collaboration for faster decisions and lower
risk of non-compliance or under-performance in
supply.
6. Putting the digital thread in life sciences (DTLS)
to use
A biopharma client with one of the
most exciting pipelines in the
industry.
Looking to create a digital bridge
between R&D through
manufacturing to enhance new
product launch capability.
New product introduction and
technology transfer is historically
paper driven, time and effort
intensive and error prone.
This creates risk of delays in
product launch and ripple effects
in wider portfolio.
Leveraged and enhanced existing
IT platforms to create a digital
product profile and digitization of
the manufacturing control
strategy.
Initial pilot on a biologic tech
transfer resulted in more than 20%
reduction in effort.
The
opportunity
The typical
challenges
The DTLS
outcome
7. Migrate and
free-up resources
Accelerating the digital thread with cloud
Adopt modern
application
development
practices
Gain faster,
deeper insights
with analytics
Ensure security,
compliance
and resiliency
Organize for
speed and agility
Bridge skills
and experience
gaps rapidly
8. Technical
Outcomes
Creating end-to-end integration with DTLS
Rapid drug discovery and
accelerated clinical
development
Smart factories for small
and large molecule drugs
Holistic view
of data
Interconnected
global network
Lifesaving treatments
reach more patients
Rapidly scale up manufacturing to support new clinical
and commercial launches
Quickly evaluate manufacturing feasibility with rapid feedback to
development cycle
Create end-to-end visibility by integrating operational manufacturing
information from disparate systems
Seamlessly bring data together across data lakes and source
systems to enable additional processing or transfer of information
9. The unique business relationship
between Accenture and AWS delivers deep
technicalexpertise, extensive life sciences domain
experience and investments in breakthrough
innovations
Powering the new frontier of a connected data-
driven life sciences industry.
What makes our
partnership special?
Helping clients achieve a new level of innovation
and efficiency across their operations and value
chain.
Access to a vast portfolio of cloud services combined
with unmatched reliability, security and data
privacy.
10. Multi-disciplinary engagement can help drive end-to
end innovation and transformation in life sciences
How do I get started?
Connect with your Accenture
and AWS team to co-create a
solution for an industry-wide
challenge.
Am I right for this?
We are looking for those
responsible for clinical supply,
tech operations, commercial
supply and CMC regulation.
Accenture.com/DigitalThread
Editor's Notes
MODERATOR (1MIN)
STUART (4MIN)
1 min: Introduction (Why are we here and what do we want to leave you as as take-home message)
Acceleration in pace of innovation is great but purpose of this talk is to discuss how we can help avoid bottlenecks in the E2E journey from bench-to-beside
We will “lean in” particularly to the potential challenges in supply (clinical and commercial) and propose approaches to avoid supply being on the critical path of continued innovation
1 min: Talking points on the “lessons of last year”
We moved on from sequencing of the CoronaVirus to developing and supplying a multitude of diagnostics, vaccines and therapeutics
We saw the validation of an entirely novel modality in the form of mRNA
2 min Talking points on the pace of innovation:
New Science is here and driving growth (81%), revenue (61%) and ROI (69% higher NPV – in part due to speed and higher success rates) (beyond Covid, look at what is happening in Oncology, Alzheimers, Inflammatory disease and gene therapy for rare diseases)
Number of treatment candidates in clinical trials are increasing (44%) and trials are becoming more complex as use of biomarkers and novel endpoints become more common
Evidence of acceleration everywhere: AI in drug discovery reduces time from 4.5 years to 1 year, virtual clinical trials increased by 50% and treatment duration decreaing by 36%
STUART (3MIN)
The pharma industry has long-held orthodoxies around the time and cost required to bring new treatments to patients buit we are seeing these orthodoxies challenged
Drug discovery is being enabled by AI tools that help a) more completely understand the complex biology of disease and b) identify the most promising target and candidate molecules to impact on the biology
Example 1:
Example 2:
2) Clinical trials can be moved away from in-person settings and can be orchestrated away from premier sites through, for example, use of advanced remote patient monitoring technology
Example 1
3) Many doubted whether, even if a vaccine was approved it could be scaled up fast enough for the pandemic, based on previous experience in scale up of supply.
But through a Herculanean effort we have seen administration of over 3.6Bn doses of vaccine
However
Vaccine supply has not been without challenges for all the players with successfully approved products and
we have seen a number of strains in the launch and supply of other novel treatments (such as Car-T cells, novel recombinant protein-based treatments and gene therapies) in the years running up to and through the pandemic .
While we believe that the industry can do more to challenge and disprove all these orthodoxies, today we will focus primarily on how we can continue to challenge orthodoxy three – utilize digityal tools to accelerating the clinical and commercial supply of novel treatments
Barry is now going to talk you through some of the ongoing challenges, opportunities and progress in orthodoxy 3 in more detail
BARRY (2MIN)
Thanks Stuart…. etc
Accelerate development: Moderna’s scientists could rapidly design mRNA candidates coding for different parts of the covid spike protein and put them into production and testing.
What if we could routinely do similar rapid early development and scale up of a wide variety of products across the spectrum of modalities
To do this we need to utilize data to better understand and control the complexity of the products attributes and how ther are impacted by the process parameters
Optimise process
Biology in the manufacturing process brings complexity, but also enormous potential for improvements. Companies who have led in using data to control the biology of their manufacturing processes (like Regeneron, Amgen, Sanofi) are starting to achieve 500-1000% higher yield of drug from their manufacturing processes compared to industry laggards. Imagine if a car company reported that could increase productivity ten fold from a facility through digitalisation!
Accelerate filing
In 2019 The FDA launched an initiative called KASA, (knowledge aided assessment & structured applications) to help pharma companies interact in a more digital way with the FDA in submission of dossiers and on topics like manufacturing/quality controls and risks. This is a great example of a regulatory body embracing innovation and really being ahead of industry. Many companies are now envisioning a “turbo-tax” like approach to making their filings on the manufacturing and control of their processes but they are still being held back in achieving this by the large amount of paper and static documents that their various teams use
Tech Transfer is a common stress point in the industry where a delicately controlled process is moved to a new location and a new team (even new companies), creating risks that subtle changes or poor exchange of knowledge may create unforeseen impacts on productivity or product quality. The more complex the process the greater the risk. In contrast, the greater the depth & sharing of knowledge of the process and all its interdependent variables, the lower the risk of unforeseen problems
BARRY (2MIN)
Digital Thread for life sciences is a tool that can help achieve all of these goals by helping to the appropriate teams (internal and third party) to collate and share deep knowledge on the product and process from the very start of R&D through scale up approval, launch and ever maturing supply
This is about harnessing enormous complex and disparate scientific and engineering data around the product and the process, surfacing insights on how the process influences the product quality and ensuring this data and knowledge is available to all the relevant personas
However we are not talking about a new “magic bullet” piece of technology but rather about more effectively harnessing existing investments in well-established tools in the industry such as ERP and GxP systems like manufacturing and quality management systems combining them with modern digital tools like AI/ML and cloud computing.
This approach provides a exciting opportunity to lower complexity and risk so lets talk about an example …
BARRY (4MIN)
Earlier I discussed the challenges and risks around tech transfer and this is a case study of a client who had become something of a victim of the success of their R&D pipeline - which was regarded as one of the hottest in the industry
(they have had a number of shortlisted by our Friends in Fierce Pharma as “most exciting” new launches in recent years
The wanted to enhance and digitalise the bridge/handoff between R&D because historically that process was paper based and extremely labor intensive, distracting both teams from day-to-day activities as they tried to mitigate risks
We worked with a multidisciplinary team in the client from R&D, regulatory affairs, manufacturing, quality. We utilized their existing ERP and manufacturing and quality systems and took account of the regulatory guidance emerging from the international congress of harmonization to convert a Quality Target Product Profile to a digital product profile. We utilized the S88 standard for batch manufacturing process control processes to create a digital process profile.
CHRIS (2MIN)
For those of you in Clinical Development, CMC, or Manufacturing, you know the importance of focusing on strategic value drivers that are most important to your organization’s success whether it be accelerating clinical development, speeding up your filings and approvals, optimizing and creating more efficient manufacturing operations, or executing flawless tech transfer between team. COVID has proven we can move quickly as an industry; however, portfolio and product complexity and the pace of new product introduction is demanding a new paradigm or new way of operating. The digital tools and capability that enable that now exists that 5-10 years ago were not even possible.
Customers that innovate with digital thread do so by leveraging the best that cloud brings. By moving to cloud, our customers are able to Migrate applications such as LIMS, MES, and QMS to free up IT resources. This additional capacity allows your teams to ceate an environment of innovation, such that you leverage data generated in the process of bringing new therapies to market in order to scale your manufacturing process globally while ensuring the necessary security, compliance and resiliency measures are in place. In doing so, companies are able to evolve their business policies in order to help break down silos between functions and create and end-to-end data strategy.
CHRIS & DAN (8 MIN)
Barry shared earlier the story of Moderna and what they were able to achieve in accelerated development. This is an incredible story. But this is only half the story. This same company is on track to make and distribute over a billion doses in just 1 year. If someone told you this 2 years ago, you would have said this is impossible? While there are many factors that contributed to the success of the industry’s response to COVID-19, companies that start by basing their technology stack in the cloud, give their teams a competitive advantage by accessing technologies that provide the agility, scalability, and responsiveness that’s needed to capitalize on such market changes.
Our customers are innovating across the value chain, which is enhanced by the Digital Thread. Of the half-dozen or so leading COVID vaccine, anti-viral, and therapeutic companies supporting the pandemic, AWS is playing a key role with two of these companies in scaling key parts of their SAP environment in order to meet the scale and volume anticipated for their production. This not only helps these companies quickly respond to the market changes, but also creates a path for introducing new approaches such as an integrated digital product profile linking clinical development to technical operations to commercial supply.
AWS is also working with companies that are specializing in new science, such as CAR-T or Biologics, where manufacturability is often on the critical path. At one of our customers, AWS is helping their clinical development team combine near real-time data capture with machine learning to quickly evaluate manufacturing feasibility in order to rapidly feedback critical information needed for establishing control strategies so that scientists can improve the process in just a fraction of the time that’s needed than with the traditional scale-up approaches.
And its not only the Biotechs and Startups. AWS is also working with established, multi-nationals, who have a broad portfolio of small molecule to gene and cell therapy and development and manufacturing facilities around the world. AWS is helping two of the top 10 Biopharma companies integrate their supply chain to create visibility from start-to-end, from raw materials to shop floor operations to commercial demand in order to predict outcomes such as batch performance or be able to mitigate risks resulting from deviations to normal operations which can have a significant impact on delays or incur unwanted costs.
A vast majority of our customers are preparing for the new normal by bringing data together across data sources within their own silos and across partners to allow data scientists to work with process scientists in order to co-create the solutions needed to deliver new product introductions with speed from benchtop to bedside
DAN -
DAN (3MIN)
We bring together Accenture’s mastery in combining technology and human ingenuity to drive extraordinary outcomes with AWS’s pioneering platform technologies to accelerate the path to value for life sciences companies. Accenture’s strength across the value chain matched with AWS’s experience creating innovative solutions matched with each of our deep technical expertise, extensive life sciences domain experience and investments in breakthrough innovations makes this partnership so special.
There is no compression algorithm for experience. There is clear advantage of working with the Life Sciences experience of Accenture and AWS versus risking it on your own. The Accenture AWS Business Group is committed to our customer obsession in helping you and patients in only successful outcomes. Think about where you are in your journey to solving more patient diseases or therapies. Think about the power of what you heard today to speed those goals. And then, contact a business partner at Accenture or AWS to enable your plan.
DAN (5MIN)
If you are responsible for 1) clinical supply, 2) technical operations, 3) commercial supply or 4) CMC regulatory affairs and are feeling excitement and trepidation from developments in New Science ... then we want to collaborate with you and multidisciplinary teams from your company