During the 15th and 16th centuries, Portugal established a large colonial trading empire beginning with the conquest of Ceuta in 1415. Key figures like Vasco de Gama and Prince Henry the Navigator helped expand Portuguese trade and exploration, reaching India and rounding the Cape of Good Hope. In 1500, Portugal claimed Brazil for King Manuel I. Sugarcane farming and the African slave trade then grew significantly in colonial Brazil as sugar became the most important crop.