This document summarizes a presentation on myofascial web and fibromyalgia. It discusses how fibromyalgia pain is generated from hypersensitive central nervous system processing and muscle tissue. Fascia, the connective tissue surrounding muscles, plays an important role as it becomes inflamed, tense and prone to "knotting up" in the form of myofascial trigger points in fibromyalgia patients. Treatments discussed include myofascial release therapy, trigger point injections, and self-care. A study found myofascial release therapy significantly improved fibromyalgia pain and tender points and the effects persisted over time compared to sham ultrasound. Another study found patients receiving myofascial release therapy experienced greater improvements in a fibromyalgia impact questionnaire than those receiving massage.